PMC:7301188 / 3533-4837 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T30","span":{"begin":88,"end":94},"obj":"NCBITaxon:859912"},{"id":"T31","span":{"begin":399,"end":408},"obj":"UBERON:0002048"},{"id":"T32","span":{"begin":482,"end":499},"obj":"UBERON:0000065"},{"id":"T33","span":{"begin":514,"end":523},"obj":"UBERON:0002048"},{"id":"T34","span":{"begin":605,"end":616},"obj":"UBERON:0001004"},{"id":"T35","span":{"begin":707,"end":715},"obj":"UBERON:0001637"},{"id":"T36","span":{"begin":874,"end":883},"obj":"UBERON:0002048"},{"id":"T37","span":{"begin":967,"end":978},"obj":"UBERON:0001004"},{"id":"T38","span":{"begin":1075,"end":1080},"obj":"UBERON:0000062"},{"id":"T39","span":{"begin":1298,"end":1303},"obj":"GO:0016265"},{"id":"T55122","span":{"begin":88,"end":94},"obj":"NCBITaxon:859912"},{"id":"T25183","span":{"begin":399,"end":408},"obj":"UBERON:0002048"},{"id":"T28285","span":{"begin":482,"end":499},"obj":"UBERON:0000065"},{"id":"T87513","span":{"begin":514,"end":523},"obj":"UBERON:0002048"},{"id":"T92813","span":{"begin":605,"end":616},"obj":"UBERON:0001004"},{"id":"T4800","span":{"begin":707,"end":715},"obj":"UBERON:0001637"},{"id":"T31469","span":{"begin":874,"end":883},"obj":"UBERON:0002048"},{"id":"T70684","span":{"begin":967,"end":978},"obj":"UBERON:0001004"},{"id":"T87749","span":{"begin":1075,"end":1080},"obj":"UBERON:0000062"},{"id":"T90276","span":{"begin":1298,"end":1303},"obj":"GO:0016265"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":482,"end":499},"obj":"Body_part"},{"id":"T5","span":{"begin":1075,"end":1080},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma265130"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma67498"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":482,"end":499},"obj":"Body_part"},{"id":"T4","span":{"begin":1075,"end":1080},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PubTator","denotations":[{"id":"106","span":{"begin":210,"end":216},"obj":"Species"},{"id":"107","span":{"begin":811,"end":819},"obj":"Species"},{"id":"108","span":{"begin":652,"end":658},"obj":"Chemical"},{"id":"109","span":{"begin":736,"end":742},"obj":"Chemical"},{"id":"110","span":{"begin":750,"end":756},"obj":"Chemical"},{"id":"111","span":{"begin":772,"end":776},"obj":"Chemical"},{"id":"112","span":{"begin":88,"end":113},"obj":"Disease"},{"id":"113","span":{"begin":399,"end":408},"obj":"Disease"},{"id":"114","span":{"begin":472,"end":477},"obj":"Disease"},{"id":"115","span":{"begin":482,"end":508},"obj":"Disease"},{"id":"116","span":{"begin":514,"end":523},"obj":"Disease"},{"id":"117","span":{"begin":605,"end":625},"obj":"Disease"},{"id":"118","span":{"begin":967,"end":986},"obj":"Disease"},{"id":"119","span":{"begin":1075,"end":1088},"obj":"Disease"},{"id":"121","span":{"begin":1155,"end":1162},"obj":"Disease"},{"id":"123","span":{"begin":1298,"end":1303},"obj":"Disease"}],"attributes":[{"id":"A106","pred":"tao:has_database_id","subj":"106","obj":"Tax:9606"},{"id":"A107","pred":"tao:has_database_id","subj":"107","obj":"Tax:9606"},{"id":"A108","pred":"tao:has_database_id","subj":"108","obj":"MESH:D010100"},{"id":"A109","pred":"tao:has_database_id","subj":"109","obj":"MESH:D010100"},{"id":"A110","pred":"tao:has_database_id","subj":"110","obj":"MESH:D010100"},{"id":"A112","pred":"tao:has_database_id","subj":"112","obj":"MESH:C000657245"},{"id":"A113","pred":"tao:has_database_id","subj":"113","obj":"MESH:D011014"},{"id":"A114","pred":"tao:has_database_id","subj":"114","obj":"MESH:D005334"},{"id":"A115","pred":"tao:has_database_id","subj":"115","obj":"MESH:D012140"},{"id":"A116","pred":"tao:has_database_id","subj":"116","obj":"MESH:D011014"},{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"MESH:D012128"},{"id":"A118","pred":"tao:has_database_id","subj":"118","obj":"MESH:D012131"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"MESH:D009102"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"MESH:D002908"},{"id":"A123","pred":"tao:has_database_id","subj":"123","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":88,"end":113},"obj":"Disease"},{"id":"T42","span":{"begin":399,"end":408},"obj":"Disease"},{"id":"T43","span":{"begin":514,"end":523},"obj":"Disease"},{"id":"T44","span":{"begin":967,"end":986},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0021113"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T37","span":{"begin":95,"end":100},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T38","span":{"begin":690,"end":691},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T39","span":{"begin":707,"end":715},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T40","span":{"begin":707,"end":715},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T41","span":{"begin":862,"end":864},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T42","span":{"begin":1075,"end":1080},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T25","span":{"begin":627,"end":629},"obj":"Chemical"},{"id":"T26","span":{"begin":652,"end":658},"obj":"Chemical"},{"id":"T27","span":{"begin":736,"end":742},"obj":"Chemical"},{"id":"T28","span":{"begin":750,"end":756},"obj":"Chemical"}],"attributes":[{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_73811"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-sentences","denotations":[{"id":"T37","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T38","span":{"begin":5,"end":29},"obj":"Sentence"},{"id":"T39","span":{"begin":31,"end":37},"obj":"Sentence"},{"id":"T40","span":{"begin":38,"end":57},"obj":"Sentence"},{"id":"T41","span":{"begin":58,"end":114},"obj":"Sentence"},{"id":"T42","span":{"begin":115,"end":810},"obj":"Sentence"},{"id":"T43","span":{"begin":811,"end":1135},"obj":"Sentence"},{"id":"T44","span":{"begin":1137,"end":1143},"obj":"Sentence"},{"id":"T45","span":{"begin":1144,"end":1162},"obj":"Sentence"},{"id":"T46","span":{"begin":1163,"end":1304},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":399,"end":408},"obj":"Phenotype"},{"id":"T4","span":{"begin":472,"end":477},"obj":"Phenotype"},{"id":"T5","span":{"begin":514,"end":523},"obj":"Phenotype"},{"id":"T6","span":{"begin":605,"end":625},"obj":"Phenotype"},{"id":"T7","span":{"begin":967,"end":986},"obj":"Phenotype"},{"id":"T8","span":{"begin":1035,"end":1040},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0002878"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0031273"}],"text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death."}