PMC:7299399 / 28296-28677 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T116","span":{"begin":159,"end":163},"obj":"Body_part"},{"id":"T117","span":{"begin":159,"end":161},"obj":"Body_part"},{"id":"T118","span":{"begin":168,"end":179},"obj":"Body_part"},{"id":"T119","span":{"begin":277,"end":285},"obj":"Body_part"},{"id":"T120","span":{"begin":289,"end":300},"obj":"Body_part"}],"attributes":[{"id":"A116","pred":"fma_id","subj":"T116","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A117","pred":"fma_id","subj":"T117","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A118","pred":"fma_id","subj":"T118","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A119","pred":"fma_id","subj":"T119","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A120","pred":"fma_id","subj":"T120","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T272","span":{"begin":19,"end":28},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T273","span":{"begin":233,"end":238},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T211","span":{"begin":159,"end":161},"obj":"Chemical"},{"id":"T213","span":{"begin":192,"end":196},"obj":"Chemical"},{"id":"T214","span":{"begin":221,"end":229},"obj":"Chemical"}],"attributes":[{"id":"A211","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A212","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A213","pred":"chebi_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/CHEBI_74768"},{"id":"A214","pred":"chebi_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/CHEBI_60809"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T34","span":{"begin":5,"end":18},"obj":"http://purl.obolibrary.org/obo/GO_0045087"},{"id":"T35","span":{"begin":19,"end":28},"obj":"http://purl.obolibrary.org/obo/GO_0023052"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}

{"project":"LitCovid-PubTator","denotations":[{"id":"427","span":{"begin":128,"end":133},"obj":"Gene"},{"id":"428","span":{"begin":159,"end":164},"obj":"Gene"},{"id":"429","span":{"begin":233,"end":238},"obj":"Species"},{"id":"430","span":{"begin":90,"end":92},"obj":"Chemical"},{"id":"431","span":{"begin":192,"end":196},"obj":"Chemical"}],"attributes":[{"id":"A427","pred":"tao:has_database_id","subj":"427","obj":"Gene:114548"},{"id":"A428","pred":"tao:has_database_id","subj":"428","obj":"Gene:3552"},{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"Tax:9606"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"MESH:C000628730"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}

{"project":"2_test","denotations":[{"id":"32519842-26389709-158518","span":{"begin":180,"end":182},"obj":"26389709"}],"text":" the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism. These results suggest that nanomaterial"}