PMC:7294857 / 3591-4351 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7294857","sourcedb":"PMC","sourceid":"7294857","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7294857","text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases 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