PMC:7294857 / 3591-4351 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T57","span":{"begin":118,"end":126},"obj":"SP_10"},{"id":"T58","span":{"begin":131,"end":139},"obj":"SP_9"},{"id":"T59","span":{"begin":157,"end":162},"obj":"G_3;PG_10;PR:000003622"},{"id":"T60","span":{"begin":177,"end":189},"obj":"GO:0009986"},{"id":"T61","span":{"begin":213,"end":225},"obj":"CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T62","span":{"begin":257,"end":262},"obj":"NCBITaxon:10239"},{"id":"T63","span":{"begin":268,"end":276},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T64","span":{"begin":294,"end":326},"obj":"GO:0042611"},{"id":"T65","span":{"begin":328,"end":331},"obj":"GO:0042611"},{"id":"T66","span":{"begin":341,"end":348},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T67","span":{"begin":367,"end":370},"obj":"PR:000004122"},{"id":"T68","span":{"begin":384,"end":392},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T69","span":{"begin":430,"end":441},"obj":"CL:0000542"},{"id":"T70","span":{"begin":482,"end":487},"obj":"UBERON:0001443"},{"id":"T71","span":{"begin":498,"end":503},"obj":"UBERON:0001443"},{"id":"T72","span":{"begin":580,"end":592},"obj":"UBERON:0005169"},{"id":"T73","span":{"begin":625,"end":630},"obj":"UBERON:0000170"},{"id":"T10319","span":{"begin":118,"end":126},"obj":"SP_10"},{"id":"T82872","span":{"begin":131,"end":139},"obj":"SP_9"},{"id":"T62155","span":{"begin":157,"end":162},"obj":"G_3;PG_10;PR:000003622"},{"id":"T17817","span":{"begin":177,"end":189},"obj":"GO:0009986"},{"id":"T2158","span":{"begin":213,"end":225},"obj":"CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T92164","span":{"begin":257,"end":262},"obj":"NCBITaxon:10239"},{"id":"T37102","span":{"begin":268,"end":276},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T75181","span":{"begin":294,"end":326},"obj":"GO:0042611"},{"id":"T51529","span":{"begin":328,"end":331},"obj":"GO:0042611"},{"id":"T51592","span":{"begin":341,"end":348},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T96320","span":{"begin":367,"end":370},"obj":"PR:000004122"},{"id":"T73219","span":{"begin":384,"end":392},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T21612","span":{"begin":430,"end":441},"obj":"CL:0000542"},{"id":"T74785","span":{"begin":482,"end":487},"obj":"UBERON:0001443"},{"id":"T33890","span":{"begin":498,"end":503},"obj":"UBERON:0001443"},{"id":"T29748","span":{"begin":580,"end":592},"obj":"UBERON:0005169"},{"id":"T58313","span":{"begin":625,"end":630},"obj":"UBERON:0000170"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T8","span":{"begin":177,"end":189},"obj":"Body_part"},{"id":"T9","span":{"begin":177,"end":181},"obj":"Body_part"},{"id":"T10","span":{"begin":213,"end":225},"obj":"Body_part"},{"id":"T11","span":{"begin":294,"end":326},"obj":"Body_part"},{"id":"T12","span":{"begin":328,"end":331},"obj":"Body_part"},{"id":"T13","span":{"begin":341,"end":365},"obj":"Body_part"},{"id":"T14","span":{"begin":360,"end":365},"obj":"Body_part"},{"id":"T15","span":{"begin":430,"end":441},"obj":"Body_part"},{"id":"T16","span":{"begin":468,"end":473},"obj":"Body_part"},{"id":"T17","span":{"begin":482,"end":487},"obj":"Body_part"},{"id":"T18","span":{"begin":498,"end":503},"obj":"Body_part"},{"id":"T19","span":{"begin":625,"end":630},"obj":"Body_part"}],"attributes":[{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma67653"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma84079"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma84079"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma273565"},{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma68877"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T5","span":{"begin":482,"end":487},"obj":"Body_part"},{"id":"T6","span":{"begin":498,"end":503},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T24","span":{"begin":118,"end":122},"obj":"Disease"}],"attributes":[{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T38","span":{"begin":177,"end":181},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T39","span":{"begin":257,"end":262},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T40","span":{"begin":360,"end":365},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T41","span":{"begin":468,"end":473},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T42","span":{"begin":482,"end":487},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T43","span":{"begin":498,"end":503},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T44","span":{"begin":625,"end":630},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":213,"end":225},"obj":"Chemical"},{"id":"T13","span":{"begin":268,"end":276},"obj":"Chemical"},{"id":"T14","span":{"begin":341,"end":348},"obj":"Chemical"},{"id":"T15","span":{"begin":367,"end":370},"obj":"Chemical"},{"id":"T16","span":{"begin":384,"end":392},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_80551"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":10,"end":22},"obj":"http://purl.obolibrary.org/obo/GO_0009405"},{"id":"T2","span":{"begin":294,"end":326},"obj":"http://purl.obolibrary.org/obo/GO_0046776"},{"id":"T3","span":{"begin":328,"end":331},"obj":"http://purl.obolibrary.org/obo/GO_0046776"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-sentences","denotations":[{"id":"T30","span":{"begin":0,"end":233},"obj":"Sentence"},{"id":"T31","span":{"begin":234,"end":372},"obj":"Sentence"},{"id":"T32","span":{"begin":373,"end":478},"obj":"Sentence"},{"id":"T33","span":{"begin":479,"end":656},"obj":"Sentence"},{"id":"T34","span":{"begin":657,"end":760},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}

{"project":"LitCovid-PubTator","denotations":[{"id":"108","span":{"begin":157,"end":162},"obj":"Gene"},{"id":"109","span":{"begin":118,"end":126},"obj":"Species"},{"id":"110","span":{"begin":131,"end":139},"obj":"Species"},{"id":"111","span":{"begin":459,"end":467},"obj":"Disease"}],"attributes":[{"id":"A108","pred":"tao:has_database_id","subj":"108","obj":"Gene:59272"},{"id":"A109","pred":"tao:has_database_id","subj":"109","obj":"Tax:694009"},{"id":"A110","pred":"tao:has_database_id","subj":"110","obj":"Tax:1335626"},{"id":"A111","pred":"tao:has_database_id","subj":"111","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The exact pathogenesis is currently unknown; however, it is suggested that it is most likely to be similar to that of SARS CoV and MERS CoV, which attach to ACE 2 enzyme on the cell surface with the help of their glycoprotein spikes. After the entry of the virus, its antigens are presented to major histocompatibility complex (MHC) via the antigen-presenting cells (APC). Then these antigens are recognized by specific cytotoxic lymphocytes that destroy the infected cells [4]. On chest X-ray and chest computed tomography (CT), ground-glass opacities, patchy consolidation, and interstitial changes at the periphery of the lungs are typical findings [7]. Real-time polymerase chain reaction (RT-PCR) is used to make the diagnosis of the suspected cases [4]. "}