PMC:7258756 / 28202-29302 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7258756","sourcedb":"PMC","sourceid":"7258756","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7258756","text":"Supplementary Table IV Conformational B-cell epitopes predicted using the modelled structure of the spike protein (template used: 6ACC.PDB; 87.29% identity). (A) Ellipro server (using a protusion Index threshold of 0.9) (B) DiscoTope server\nA. Ellipro epitope prediction\nEpitope number Epitope residues Epitope score\n1 244-RSYLTPGDSSSGW-256 0.95\n2 347S, 349Y, 419Y, 441-SKVGGNYNYLYRLFR-455, 457S, 465-DISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTN -499 0.943\n3 1074 TTAPAICHDGKAHFPR 1089, 1094-VSNGTHWFV-1102, 1110- PQIITTDNTFVSGNCDVVIGIVNNTV-1135 0.934\n4 144-HKNNKSWMESE-154 0.912\n5 72-GTNGTK-77 0.907\nB. DiscoTope epitope prediction\nG72, T73, N74, G75, K145, N146, N147, K148, S149, L174, E178, K180, Q181, G182, 183, V211, S245, Y246, L247, T248, P249, G250, D251, S252, S253, K415, N438, S441, K442, V443, G444, G445, N446, Y447, N448, K456, S457, N458, K460, A473, G474, S475, S492, G494, Q496, P497, T498, N499, G500, V501, Y503, N554, K556, L558, P559, I567, Q675, T676, N677, S678, P679, R680, R681, A682, R683, S702, V703, A704, Y705, T714, P791, P807, S808, K809, P810, E916, Q1069, 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