PMC:7247521 / 38545-39448 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"633","span":{"begin":108,"end":142},"obj":"Gene"},{"id":"634","span":{"begin":250,"end":254},"obj":"Gene"},{"id":"635","span":{"begin":305,"end":309},"obj":"Gene"},{"id":"636","span":{"begin":365,"end":373},"obj":"Gene"},{"id":"637","span":{"begin":428,"end":436},"obj":"Gene"},{"id":"639","span":{"begin":61,"end":70},"obj":"Species"},{"id":"641","span":{"begin":888,"end":891},"obj":"Disease"}],"attributes":[{"id":"A634","pred":"tao:has_database_id","subj":"634","obj":"Gene:43740578"},{"id":"A635","pred":"tao:has_database_id","subj":"635","obj":"Gene:43740578"},{"id":"A636","pred":"tao:has_database_id","subj":"636","obj":"Gene:164045"},{"id":"A637","pred":"tao:has_database_id","subj":"637","obj":"Gene:164045"},{"id":"A639","pred":"tao:has_database_id","subj":"639","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T581","span":{"begin":61,"end":70},"obj":"SP_7"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T147","span":{"begin":71,"end":79},"obj":"Body_part"},{"id":"T148","span":{"begin":260,"end":263},"obj":"Body_part"},{"id":"T149","span":{"begin":318,"end":321},"obj":"Body_part"},{"id":"T150","span":{"begin":497,"end":501},"obj":"Body_part"},{"id":"T151","span":{"begin":741,"end":748},"obj":"Body_part"},{"id":"T152","span":{"begin":801,"end":808},"obj":"Body_part"}],"attributes":[{"id":"A147","pred":"fma_id","subj":"T147","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A148","pred":"fma_id","subj":"T148","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A149","pred":"fma_id","subj":"T149","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma84120"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T329","span":{"begin":90,"end":93},"obj":"http://purl.obolibrary.org/obo/CLO_0007875"},{"id":"T330","span":{"begin":90,"end":93},"obj":"http://purl.obolibrary.org/obo/CLO_0052410"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T324","span":{"begin":71,"end":79},"obj":"Chemical"},{"id":"T325","span":{"begin":374,"end":377},"obj":"Chemical"},{"id":"T328","span":{"begin":741,"end":748},"obj":"Chemical"},{"id":"T329","span":{"begin":801,"end":808},"obj":"Chemical"},{"id":"T330","span":{"begin":809,"end":812},"obj":"Chemical"}],"attributes":[{"id":"A324","pred":"chebi_id","subj":"T324","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A325","pred":"chebi_id","subj":"T325","obj":"http://purl.obolibrary.org/obo/CHEBI_16761"},{"id":"A326","pred":"chebi_id","subj":"T325","obj":"http://purl.obolibrary.org/obo/CHEBI_456216"},{"id":"A327","pred":"chebi_id","subj":"T325","obj":"http://purl.obolibrary.org/obo/CHEBI_73342"},{"id":"A328","pred":"chebi_id","subj":"T328","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A329","pred":"chebi_id","subj":"T329","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A330","pred":"chebi_id","subj":"T330","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T103","span":{"begin":809,"end":820},"obj":"http://purl.obolibrary.org/obo/GO_0022831"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-sentences","denotations":[{"id":"T285","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T286","span":{"begin":81,"end":128},"obj":"Sentence"},{"id":"T287","span":{"begin":129,"end":185},"obj":"Sentence"},{"id":"T288","span":{"begin":186,"end":249},"obj":"Sentence"},{"id":"T289","span":{"begin":250,"end":304},"obj":"Sentence"},{"id":"T290","span":{"begin":305,"end":364},"obj":"Sentence"},{"id":"T291","span":{"begin":365,"end":427},"obj":"Sentence"},{"id":"T292","span":{"begin":428,"end":490},"obj":"Sentence"},{"id":"T293","span":{"begin":491,"end":545},"obj":"Sentence"},{"id":"T294","span":{"begin":546,"end":606},"obj":"Sentence"},{"id":"T295","span":{"begin":607,"end":675},"obj":"Sentence"},{"id":"T296","span":{"begin":676,"end":738},"obj":"Sentence"},{"id":"T297","span":{"begin":739,"end":798},"obj":"Sentence"},{"id":"T298","span":{"begin":799,"end":866},"obj":"Sentence"},{"id":"T299","span":{"begin":867,"end":895},"obj":"Sentence"},{"id":"T300","span":{"begin":896,"end":903},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T8","span":{"begin":121,"end":124},"obj":"GlycoEpitope"}],"attributes":[{"id":"A8","pred":"glyco_epitope_db_id","subj":"T8","obj":"http://www.glycoepitope.jp/epitopes/AN0690"}],"text":"Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.\nMolecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1\nMain Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4\nPapain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3\nRdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5\nRdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1\nHelicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8\nHelicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5\nNsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1\nNsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7\nNsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6\nNsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2\nN protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9\nE protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8\nM: MXSG, S: SGMH, X: XCH, O: Others."}