PMC:7219429 / 19457-19838
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T112 | 35-42 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T113 | 60-65 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T114 | 87-99 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T115 | 373-380 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T72 | 356-359 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T193 | 7-9 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T194 | 58-59 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T195 | 200-202 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T196 | 326-327 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T344 | 7-9 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
| T345 | 25-28 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T348 | 35-42 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T349 | 60-65 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T350 | 83-86 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T353 | 87-99 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T354 | 123-134 | Chemical | denotes | cholesterol | http://purl.obolibrary.org/obo/CHEBI_16113 |
| T355 | 136-140 | Chemical | denotes | chol | http://purl.obolibrary.org/obo/CHEBI_16113 |
| T356 | 150-163 | Chemical | denotes | sphingomyelin | http://purl.obolibrary.org/obo/CHEBI_17636|http://purl.obolibrary.org/obo/CHEBI_64583 |
| T358 | 165-167 | Chemical | denotes | SM | http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_74817|http://purl.obolibrary.org/obo/CHEBI_17636 |
| T361 | 169-175 | Chemical | denotes | lipids | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T362 | 200-202 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
| T363 | 286-297 | Chemical | denotes | Cholesterol | http://purl.obolibrary.org/obo/CHEBI_16113 |
| T364 | 302-315 | Chemical | denotes | sphingomyelin | http://purl.obolibrary.org/obo/CHEBI_17636|http://purl.obolibrary.org/obo/CHEBI_64583 |
| T366 | 337-340 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T369 | 373-380 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T21 | 25-28 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T22 | 83-86 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T23 | 337-340 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T143 | 0-78 | Sentence | denotes | Fig. 6 MD simulations of GM1-spike protein interaction in a lipid raft domain. |
| T144 | 79-176 | Sentence | denotes | Two GM1 gangliosides were merged with eight cholesterol (chol) and two sphingomyelin (SM) lipids. |
| T145 | 177-240 | Sentence | denotes | After initial docking, MD simulations were performed for 50 ns. |
| T146 | 241-285 | Sentence | denotes | Two distinct views of the complex are shown. |
| T147 | 286-381 | Sentence | denotes | Cholesterol and sphingomyelin stabilize a dimer of GM1 clamped by the NTD of the spike protein. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 457 | 367-372 | Gene | denotes | spike | Gene:43740568 |
| 458 | 25-28 | Chemical | denotes | GM1 | MESH:D005677 |
| 459 | 60-65 | Chemical | denotes | lipid | MESH:D008055 |
| 460 | 83-86 | Chemical | denotes | GM1 | MESH:D005677 |
| 461 | 87-99 | Chemical | denotes | gangliosides | MESH:D005732 |
| 462 | 123-134 | Chemical | denotes | cholesterol | MESH:D002784 |
| 463 | 136-140 | Chemical | denotes | chol | MESH:D002784 |
| 464 | 150-163 | Chemical | denotes | sphingomyelin | MESH:D013109 |
| 465 | 165-167 | Chemical | denotes | SM | MESH:D013109 |
| 466 | 169-175 | Chemical | denotes | lipids | MESH:D008055 |
| 467 | 286-297 | Chemical | denotes | Cholesterol | MESH:D002784 |
| 468 | 302-315 | Chemical | denotes | sphingomyelin | MESH:D013109 |
| 469 | 337-340 | Chemical | denotes | GM1 | MESH:D005677 |