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PMC:7219429 / 12084-13415 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T64 32-39 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T65 51-62 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T66 136-147 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T67 348-356 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T68 604-615 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T69 818-829 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T70 975-986 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T71 1009-1020 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T72 1085-1088 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T73 1184-1191 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T74 1325-1330 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T4 83-86 Body_part denotes tip http://purl.obolibrary.org/obo/UBERON_2001840
T5 719-722 Body_part denotes tip http://purl.obolibrary.org/obo/UBERON_2001840
T6 1228-1244 Body_part denotes attachment sites http://purl.obolibrary.org/obo/UBERON_4200047

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T40 15-23 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T41 94-97 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T43 232-240 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 546-549 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T46 567-570 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T119 49-50 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 133-134 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T121 374-379 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T122 571-574 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T123 575-576 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T124 781-784 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T125 785-786 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T126 816-817 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 1069-1076 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T128 1175-1176 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T129 1276-1277 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 1325-1330 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T216 32-39 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T217 51-62 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T218 125-128 Chemical denotes ATM http://purl.obolibrary.org/obo/CHEBI_2955
T219 136-147 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T220 348-356 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T221 392-398 Chemical denotes corona http://purl.obolibrary.org/obo/CHEBI_37409
T222 413-421 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T223 604-615 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T224 818-829 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T225 975-986 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T226 1009-1020 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T227 1122-1133 Chemical denotes neurotoxins http://purl.obolibrary.org/obo/CHEBI_50910
T228 1184-1191 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T4 1309-1324 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into host

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T88 0-200 Sentence denotes Given that the SARS-CoV-2 spike protein displays a ganglioside-binding site at the tip of its NTD [10], the possibility that ATM, as a “ganglioside mimic”, could also bind to this site was considered.
T89 201-305 Sentence denotes The structural features of the SARS-CoV-2 spike in the prefusion conformation [20] are shown in Fig. 1c.
T90 306-440 Sentence denotes It consists of three interdigitated spike proteins that provide the virus its typical corona-like shape in electron microscopy images.
T91 441-562 Sentence denotes In each subunit, the most distant part from the viral envelope is divided into two separate domains, the NTD and the RBD.
T92 563-742 Sentence denotes The NTD has a flat surface available for ganglioside binding [10], and this process is independent from the ACE-2 receptor recognition, which occurs at the tip of the RBD [11,20].
T93 743-858 Sentence denotes When seen from above, the viral spike has a typical triangle shape, with a ganglioside-binding domain at each apex.
T94 859-998 Sentence denotes Thus, the spike central area is devoted to ACE-2 binding, leaving three peripheric flat surface areas available for ganglioside attachment.
T95 999-1139 Sentence denotes Such dual ganglioside/receptor binding is commonly used by pathogenic viruses such as HIV-1 [28], [29], [30] and bacterial neurotoxins [16].
T96 1140-1331 Sentence denotes By combining the high affinity for a single protein receptor with multiple low affinity attachment sites, these pathogens have selected a very efficient pathway to gain entry into host cells.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
350 26-31 Gene denotes spike Gene:43740568
351 671-676 Gene denotes ACE-2 Gene:59272
352 902-907 Gene denotes ACE-2 Gene:59272
353 869-874 Gene denotes spike Gene:43740568
354 775-780 Gene denotes spike Gene:43740568
355 342-347 Gene denotes spike Gene:43740568
356 243-248 Gene denotes spike Gene:43740568
357 15-25 Species denotes SARS-CoV-2 Tax:2697049
358 232-242 Species denotes SARS-CoV-2 Tax:2697049
359 51-62 Chemical denotes ganglioside MESH:D005732
360 136-147 Chemical denotes ganglioside MESH:D005732
361 604-615 Chemical denotes ganglioside MESH:D005732
362 818-829 Chemical denotes ganglioside MESH:D005732
363 1009-1020 Chemical denotes ganglioside MESH:D005732
364 975-997 Disease denotes ganglioside attachment MESH:D005733
365 1085-1133 Disease denotes HIV-1 [28], [29], [30] and bacterial neurotoxins MESH:D016920

2_test

Id Subject Object Predicate Lexical cue
32405156-32075877-48151023 280-282 32075877 denotes 20
32405156-32132184-48151024 735-737 32132184 denotes 11
32405156-32075877-48151025 738-740 32075877 denotes 20
32405156-31431523-48151026 1135-1137 31431523 denotes 16
T54896 280-282 32075877 denotes 20
T86066 735-737 32132184 denotes 11
T70176 738-740 32075877 denotes 20
T42537 1135-1137 31431523 denotes 16