| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T96 |
0-21 |
Sentence |
denotes |
Certainty of Evidence |
| T97 |
22-152 |
Sentence |
denotes |
Certainty of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) framework. |
| T98 |
153-239 |
Sentence |
denotes |
The certainty of evidence was categorized into 4 levels ranging from very low to high. |
| T99 |
240-541 |
Sentence |
denotes |
Within the GRADE framework, evidence from randomized controlled trials (RCTs) starts as high-certainty evidence and observational studies start out as low-certainty evidence, but can be rated down for the following reasons: risk of bias, inconsistency, indirectness, imprecision, and publication bias. |
| T100 |
542-697 |
Sentence |
denotes |
Additionally, evidence from well-conducted observational studies start as low-certainty evidence, but can be rated up for large effects or dose–response.14 |
