PMC:7205724 / 26104-26941
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 920 | 23-27 | Gene | denotes | ACE2 | Gene:59272 |
| 921 | 32-38 | Chemical | denotes | copper | MESH:D003300 |
| 935 | 70-99 | Gene | denotes | angiotensin-converting enzyme | Gene:24310 |
| 936 | 101-104 | Gene | denotes | ACE | Gene:24310 |
| 937 | 238-242 | Gene | denotes | ACE2 | Gene:59272 |
| 938 | 244-254 | Gene | denotes | E-cadherin | Gene:999 |
| 939 | 256-262 | Gene | denotes | ABCB-1 | Gene:5243 |
| 940 | 268-273 | Gene | denotes | IRF-8 | Gene:3394 |
| 941 | 471-477 | Gene | denotes | ICAM-1 | Gene:3383 |
| 942 | 482-488 | Gene | denotes | VCAM-1 | Gene:7412 |
| 943 | 198-202 | Species | denotes | rats | Tax:10116 |
| 944 | 185-197 | Disease | denotes | hypertensive | MESH:D006973 |
| 945 | 306-317 | Disease | denotes | hyperplasia | MESH:D006965 |
| 946 | 332-344 | Disease | denotes | inflammation | MESH:D007249 |
| 947 | 539-560 | Disease | denotes | vascular inflammation | MESH:D007249 |
| 953 | 768-773 | Species | denotes | quail | Tax:9091 |
| 954 | 562-568 | Chemical | denotes | Copper | MESH:D003300 |
| 955 | 644-650 | Chemical | denotes | copper | MESH:D003300 |
| 956 | 825-831 | Chemical | denotes | copper | MESH:D003300 |
| 957 | 608-624 | Disease | denotes | viral infections | MESH:D001102 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T185 | 167-172 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T186 | 244-254 | Body_part | denotes | E-cadherin | http://purl.org/sig/ont/fma/fma61792 |
| T187 | 380-390 | Body_part | denotes | leukocytes | http://purl.org/sig/ont/fma/fma62852 |
| T188 | 405-409 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T189 | 471-475 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T190 | 524-534 | Body_part | denotes | leukocytes | http://purl.org/sig/ont/fma/fma62852 |
| T191 | 584-597 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T27 | 167-172 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T28 | 405-409 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T29 | 584-597 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T30 | 670-679 | Body_part | denotes | eggshells | http://purl.obolibrary.org/obo/UBERON_0005079 |
| T31 | 718-726 | Body_part | denotes | eggshell | http://purl.obolibrary.org/obo/UBERON_0005079 |
| T32 | 761-764 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/UBERON_0007379 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T193 | 306-317 | Disease | denotes | hyperplasia | http://purl.obolibrary.org/obo/MONDO_0005043 |
| T194 | 332-344 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T195 | 548-560 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T196 | 608-624 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T295 | 117-124 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T296 | 145-148 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T297 | 167-172 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T298 | 167-172 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T299 | 246-254 | http://purl.obolibrary.org/obo/PR_000001327 | denotes | cadherin |
| T300 | 296-304 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T301 | 584-597 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T302 | 626-627 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T303 | 748-751 | http://purl.obolibrary.org/obo/CLO_0003417 | denotes | g/g |
| T304 | 788-791 | http://purl.obolibrary.org/obo/CLO_0003417 | denotes | g/g |
| T305 | 833-835 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T214 | 32-38 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
| T216 | 70-81 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T217 | 117-124 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T218 | 292-295 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
| T219 | 454-463 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T220 | 562-568 | Chemical | denotes | Copper | http://purl.obolibrary.org/obo/CHEBI_28694 |
| T221 | 644-650 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
| T223 | 825-831 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
LitCovid-sample-MedDRA
| Id | Subject | Object | Predicate | Lexical cue | meddra_id |
|---|---|---|---|---|---|
| T28 | 70-99 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | angiotensin-converting enzyme | http://purl.bioontology.org/ontology/MEDDRA/10050289 |
| T29 | 101-104 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | ACE | http://purl.bioontology.org/ontology/MEDDRA/10050289 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T123 | 167-172 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T124 | 380-390 | http://purl.obolibrary.org/obo/CL_0000738 | denotes | leukocytes |
| T125 | 524-534 | http://purl.obolibrary.org/obo/CL_0000738 | denotes | leukocytes |
| T126 | 614-624 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infections |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T134 | 32-38 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
| T136 | 70-81 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T137 | 117-124 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T138 | 292-295 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
| T139 | 562-568 | Chemical | denotes | Copper | http://purl.obolibrary.org/obo/CHEBI_28694 |
| T140 | 644-650 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
| T142 | 825-831 | Chemical | denotes | copper | http://purl.obolibrary.org/obo/CHEBI_28694|http://purl.obolibrary.org/obo/CHEBI_30052 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T237 | 198-202 | Species | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T240 | 692-697 | Species | denotes | birds | NCBItxid:8782 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T213 | 0-38 | Sentence | denotes | 8 Eggs for increasing ACE2 and copper |
| T214 | 39-208 | Sentence | denotes | Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. |
| T215 | 209-391 | Sentence | denotes | Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. |
| T216 | 392-561 | Sentence | denotes | On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation. |
| T217 | 562-625 | Sentence | denotes | Copper might help the immune system to combat viral infections. |
| T218 | 626-698 | Sentence | denotes | A High-content of copper exists in eggs and eggshells of domestic birds. |
| T219 | 699-837 | Sentence | denotes | In particular, the eggshell of pigeon (4 ± 0.29 μg/g) and the egg of quail (4.67 ± 1.08 μg/g) contains high concentrations of copper [34]. |
LitCovid-sample-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T27 | 167-172 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T28 | 405-409 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T29 | 584-597 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T30 | 670-679 | Body_part | denotes | eggshells | http://purl.obolibrary.org/obo/UBERON_0005079 |
| T31 | 718-726 | Body_part | denotes | eggshell | http://purl.obolibrary.org/obo/UBERON_0005079 |
| T32 | 761-764 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/UBERON_0007379 |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 920 | 23-27 | Gene | denotes | ACE2 | Gene:59272 |
| 921 | 32-38 | Chemical | denotes | copper | MESH:D003300 |
| 935 | 70-99 | Gene | denotes | angiotensin-converting enzyme | Gene:24310 |
| 936 | 101-104 | Gene | denotes | ACE | Gene:24310 |
| 944 | 185-197 | Disease | denotes | hypertensive | MESH:D006973 |
| 943 | 198-202 | Species | denotes | rats | Tax:10116 |
| 937 | 238-242 | Gene | denotes | ACE2 | Gene:59272 |
| 938 | 244-254 | Gene | denotes | E-cadherin | Gene:999 |
| 939 | 256-262 | Gene | denotes | ABCB-1 | Gene:5243 |
| 940 | 268-273 | Gene | denotes | IRF-8 | Gene:3394 |
| 945 | 306-317 | Disease | denotes | hyperplasia | MESH:D006965 |
| 946 | 332-344 | Disease | denotes | inflammation | MESH:D007249 |
| 941 | 471-477 | Gene | denotes | ICAM-1 | Gene:3383 |
| 942 | 482-488 | Gene | denotes | VCAM-1 | Gene:7412 |
| 947 | 539-560 | Disease | denotes | vascular inflammation | MESH:D007249 |
| 954 | 562-568 | Chemical | denotes | Copper | MESH:D003300 |
| 957 | 608-624 | Disease | denotes | viral infections | MESH:D001102 |
| 955 | 644-650 | Chemical | denotes | copper | MESH:D003300 |
| 953 | 768-773 | Species | denotes | quail | Tax:9091 |
| 956 | 825-831 | Chemical | denotes | copper | MESH:D003300 |
LitCovid-sample-UniProt
| Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
|---|---|---|---|---|---|
| T2446 | 43-57 | Protein | denotes | ovotransferrin | https://www.uniprot.org/uniprot/P85895|https://www.uniprot.org/uniprot/P56410|https://www.uniprot.org/uniprot/P02789 |
| T2449 | 70-99 | Protein | denotes | angiotensin-converting enzyme | https://www.uniprot.org/uniprot/Q9VJV3|https://www.uniprot.org/uniprot/Q9TX66|https://www.uniprot.org/uniprot/Q9NKE4|https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6Q4G4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q27572|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q10715|https://www.uniprot.org/uniprot/Q10714|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/A4V0P3 |
| T2481 | 101-104 | Protein | denotes | ACE | https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3 |
| T2506 | 244-254 | Protein | denotes | E-cadherin | https://www.uniprot.org/uniprot/Q9UII8|https://www.uniprot.org/uniprot/Q9R0T4|https://www.uniprot.org/uniprot/Q9JIV9|https://www.uniprot.org/uniprot/Q91709|https://www.uniprot.org/uniprot/Q6R8F2|https://www.uniprot.org/uniprot/Q61377|https://www.uniprot.org/uniprot/Q5RAX1|https://www.uniprot.org/uniprot/Q4PJ14|https://www.uniprot.org/uniprot/Q16194|https://www.uniprot.org/uniprot/Q15855|https://www.uniprot.org/uniprot/Q14216|https://www.uniprot.org/uniprot/Q13799|https://www.uniprot.org/uniprot/P30944|https://www.uniprot.org/uniprot/P12830|https://www.uniprot.org/uniprot/P09803|https://www.uniprot.org/uniprot/P08641|https://www.uniprot.org/uniprot/O35794|https://www.uniprot.org/uniprot/F1PAA9|https://www.uniprot.org/uniprot/A8K1U7 |
| T2525 | 268-273 | Protein | denotes | IRF-8 | https://www.uniprot.org/uniprot/Q90871|https://www.uniprot.org/uniprot/Q02556|https://www.uniprot.org/uniprot/P23611|https://www.uniprot.org/uniprot/A0AV82 |
| T2529 | 471-477 | Protein | denotes | ICAM-1 | https://www.uniprot.org/uniprot/Q96B50|https://www.uniprot.org/uniprot/Q95132|https://www.uniprot.org/uniprot/Q61828|https://www.uniprot.org/uniprot/Q5NKW2|https://www.uniprot.org/uniprot/Q5NKV9|https://www.uniprot.org/uniprot/Q5NKV7|https://www.uniprot.org/uniprot/Q5NKV6|https://www.uniprot.org/uniprot/Q5NKV4|https://www.uniprot.org/uniprot/Q28806|https://www.uniprot.org/uniprot/Q28291|https://www.uniprot.org/uniprot/Q00238|https://www.uniprot.org/uniprot/P33729|https://www.uniprot.org/uniprot/P13597|https://www.uniprot.org/uniprot/P05362|https://www.uniprot.org/uniprot/B2R6M3 |
| T2544 | 482-488 | Protein | denotes | VCAM-1 | https://www.uniprot.org/uniprot/Q6NUP8|https://www.uniprot.org/uniprot/Q63669|https://www.uniprot.org/uniprot/Q5FVS3|https://www.uniprot.org/uniprot/Q28260|https://www.uniprot.org/uniprot/P29534|https://www.uniprot.org/uniprot/P29533|https://www.uniprot.org/uniprot/P19320|https://www.uniprot.org/uniprot/E9PDD1|https://www.uniprot.org/uniprot/B4DKS4|https://www.uniprot.org/uniprot/A8K6R7 |
LitCovid-sample-Enju
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T33004 | 0-1 | CD | denotes | 8 |
| T58581 | 3-7 | NNS | denotes | Eggs |
| T97114 | 8-11 | IN | denotes | for |
| T27689 | 12-22 | VBG | denotes | increasing |
| T63081 | 23-27 | NN | denotes | ACE2 |
| T72667 | 28-31 | CC | denotes | and |
| T79511 | 32-38 | NN | denotes | copper |
| T38004 | 39-42 | NN | denotes | Egg |
| T27506 | 43-57 | NN | denotes | ovotransferrin |
| T37276 | 58-66 | VBZ | denotes | contains |
| T34098 | 67-69 | DT | denotes | an |
| T97147 | 70-92 | JJ | denotes | angiotensin-converting |
| T86608 | 93-99 | NN | denotes | enzyme |
| T66871 | 100-101 | -LRB- | denotes | ( |
| T13854 | 101-104 | NN | denotes | ACE |
| T64698 | 104-105 | -RRB- | denotes | ) |
| T83677 | 106-116 | JJ | denotes | inhibitory |
| T66003 | 117-124 | NN | denotes | peptide |
| T77918 | 124-125 | -COMMA- | denotes | , |
| T89508 | 126-131 | VBN | denotes | known |
| T88322 | 132-134 | IN | denotes | as |
| T66546 | 135-138 | NNP | denotes | IRW |
| T45851 | 138-139 | -COMMA- | denotes | , |
| T60984 | 140-144 | WDT | denotes | that |
| T46693 | 145-148 | VBZ | denotes | has |
| T76296 | 149-154 | VBN | denotes | shown |
| T28156 | 155-157 | TO | denotes | to |
| T90573 | 158-166 | VB | denotes | decrease |
| T38759 | 167-172 | NN | denotes | blood |
| T21018 | 173-181 | NN | denotes | pressure |
| T30544 | 182-184 | IN | denotes | in |
| T99198 | 185-197 | JJ | denotes | hypertensive |
| T98401 | 198-202 | NNS | denotes | rats |
| T50903 | 203-204 | -LRB- | denotes | [ |
| T33947 | 204-206 | CD | denotes | 33 |
| T14997 | 206-207 | -RRB- | denotes | ] |
| T50077 | 209-216 | IN | denotes | Through |
| T34549 | 217-220 | DT | denotes | the |
| T35438 | 221-234 | NN | denotes | up-regulation |
| T84846 | 235-237 | IN | denotes | of |
| T82446 | 238-242 | NN | denotes | ACE2 |
| T51616 | 242-243 | -COMMA- | denotes | , |
| T55154 | 244-254 | NN | denotes | E-cadherin |
| T8679 | 254-255 | -COMMA- | denotes | , |
| T45090 | 256-262 | NN | denotes | ABCB-1 |
| T32702 | 262-263 | -COMMA- | denotes | , |
| T32352 | 264-267 | CC | denotes | and |
| T2901 | 268-273 | NN | denotes | IRF-8 |
| T24097 | 273-274 | -COMMA- | denotes | , |
| T97074 | 275-278 | NNP | denotes | IRW |
| T68802 | 279-282 | MD | denotes | can |
| T39838 | 283-291 | VB | denotes | decrease |
| T60149 | 292-295 | NN | denotes | RAS |
| T50074 | 296-304 | NN | denotes | activity |
| T49953 | 304-305 | -COMMA- | denotes | , |
| T70369 | 306-317 | NN | denotes | hyperplasia |
| T91445 | 317-318 | -COMMA- | denotes | , |
| T20067 | 319-322 | CC | denotes | and |
| T30801 | 323-331 | JJ | denotes | vascular |
| T51592 | 332-344 | NN | denotes | inflammation |
| T28168 | 345-348 | CC | denotes | and |
| T93235 | 349-352 | NN | denotes | aid |
| T43180 | 353-365 | JJ | denotes | differential |
| T82201 | 366-376 | NN | denotes | regulation |
| T72254 | 377-379 | IN | denotes | of |
| T87852 | 380-390 | NNS | denotes | leukocytes |
| T80434 | 392-394 | IN | denotes | On |
| T8306 | 395-398 | DT | denotes | the |
| T52921 | 399-404 | JJ | denotes | other |
| T81543 | 405-409 | NN | denotes | hand |
| T20825 | 409-410 | -COMMA- | denotes | , |
| T78284 | 411-413 | IN | denotes | by |
| T10667 | 414-417 | DT | denotes | the |
| T59443 | 418-433 | NN | denotes | down-regulation |
| T14412 | 434-436 | IN | denotes | of |
| T13570 | 437-453 | JJ | denotes | pro-inflammatory |
| T20179 | 454-463 | NNS | denotes | molecules |
| T42843 | 463-464 | -COMMA- | denotes | , |
| T68303 | 465-469 | FW | denotes | e.g. |
| T5913 | 469-470 | -COMMA- | denotes | , |
| T53611 | 471-477 | NN | denotes | ICAM-1 |
| T22569 | 478-481 | CC | denotes | and |
| T86123 | 482-488 | NN | denotes | VCAM-1 |
| T88206 | 488-489 | -COMMA- | denotes | , |
| T14786 | 490-493 | NN | denotes | IRW |
| T56782 | 494-497 | MD | denotes | can |
| T84385 | 498-504 | VB | denotes | reduce |
| T54198 | 505-508 | DT | denotes | the |
| T53586 | 509-520 | NN | denotes | recruitment |
| T18273 | 521-523 | IN | denotes | of |
| T25763 | 524-534 | NNS | denotes | leukocytes |
| T50471 | 535-538 | CC | denotes | and |
| T39944 | 539-547 | JJ | denotes | vascular |
| T95815 | 548-560 | NN | denotes | inflammation |
| T32229 | 562-568 | NN | denotes | Copper |
| T37620 | 569-574 | MD | denotes | might |
| T49191 | 575-579 | VB | denotes | help |
| T32412 | 580-583 | DT | denotes | the |
| T49707 | 584-590 | JJ | denotes | immune |
| T77430 | 591-597 | NN | denotes | system |
| T78509 | 598-600 | TO | denotes | to |
| T84428 | 601-607 | VB | denotes | combat |
| T52262 | 608-613 | JJ | denotes | viral |
| T25569 | 614-624 | NNS | denotes | infections |
| T85825 | 626-627 | DT | denotes | A |
| T86532 | 628-640 | NN | denotes | High-content |
| T37905 | 641-643 | IN | denotes | of |
| T38135 | 644-650 | NN | denotes | copper |
| T5313 | 651-657 | VBZ | denotes | exists |
| T26683 | 658-660 | IN | denotes | in |
| T69996 | 661-665 | NNS | denotes | eggs |
| T88154 | 666-669 | CC | denotes | and |
| T28753 | 670-679 | NNS | denotes | eggshells |
| T68700 | 680-682 | IN | denotes | of |
| T82775 | 683-691 | JJ | denotes | domestic |
| T68554 | 692-697 | NNS | denotes | birds |
| T12507 | 699-701 | IN | denotes | In |
| T63866 | 702-712 | JJ | denotes | particular |
| T96163 | 712-713 | -COMMA- | denotes | , |
| T60294 | 714-717 | DT | denotes | the |
| T93066 | 718-726 | NN | denotes | eggshell |
| T75912 | 727-729 | IN | denotes | of |
| T52328 | 730-736 | NN | denotes | pigeon |
| T61958 | 737-738 | -LRB- | denotes | ( |
| T56156 | 738-739 | CD | denotes | 4 |
| T26914 | 740-741 | NN | denotes | ± |
| T94273 | 742-751 | NN | denotes | 0.29 μg/g |
| T66624 | 751-752 | -RRB- | denotes | ) |
| T87690 | 753-756 | CC | denotes | and |
| T47055 | 757-760 | DT | denotes | the |
| T46042 | 761-764 | NN | denotes | egg |
| T48696 | 765-767 | IN | denotes | of |
| T59365 | 768-773 | NN | denotes | quail |
| T45935 | 774-775 | -LRB- | denotes | ( |
| T43374 | 775-779 | CD | denotes | 4.67 |
| T68174 | 780-781 | CC | denotes | ± |
| T58925 | 782-791 | NN | denotes | 1.08 μg/g |
| T41203 | 791-792 | -RRB- | denotes | ) |
| T68835 | 793-801 | VBZ | denotes | contains |
| T5139 | 802-806 | JJ | denotes | high |
| T58590 | 807-821 | NNS | denotes | concentrations |
| T50194 | 822-824 | IN | denotes | of |
| T95116 | 825-831 | NN | denotes | copper |
| T90276 | 832-833 | -LRB- | denotes | [ |
| T72554 | 833-835 | CD | denotes | 34 |
| T34750 | 835-836 | -RRB- | denotes | ] |
| R71284 | T58581 | T33004 | arg1Of | Eggs,8 |
| R44940 | T58581 | T97114 | arg1Of | Eggs,for |
| R35818 | T27689 | T97114 | arg2Of | increasing,for |
| R37332 | T72667 | T27689 | arg2Of | and,increasing |
| R82740 | T63081 | T72667 | arg1Of | ACE2,and |
| R72853 | T79511 | T72667 | arg2Of | copper,and |
| R28892 | T27506 | T38004 | arg1Of | ovotransferrin,Egg |
| R58662 | T27506 | T37276 | arg1Of | ovotransferrin,contains |
| R39377 | T66003 | T37276 | arg2Of | peptide,contains |
| R23607 | T66003 | T34098 | arg1Of | peptide,an |
| R50549 | T66003 | T97147 | arg1Of | peptide,angiotensin-converting |
| R85317 | T66003 | T86608 | arg1Of | peptide,enzyme |
| R98182 | T66003 | T66871 | arg1Of | peptide,( |
| R25886 | T13854 | T66871 | arg2Of | ACE,( |
| R46910 | T64698 | T66871 | arg3Of | ),( |
| R16058 | T66003 | T83677 | arg1Of | peptide,inhibitory |
| R44712 | T66003 | T77918 | arg1Of | peptide,"," |
| R80780 | T66003 | T89508 | arg2Of | peptide,known |
| R26520 | T89508 | T88322 | arg1Of | known,as |
| R25376 | T66546 | T88322 | arg2Of | IRW,as |
| R32436 | T66546 | T45851 | arg1Of | IRW,"," |
| R75655 | T60984 | T46693 | arg1Of | that,has |
| R36556 | T76296 | T46693 | arg2Of | shown,has |
| R43573 | T60984 | T76296 | arg1Of | that,shown |
| R41497 | T66546 | T76296 | arg2Of | IRW,shown |
| R82274 | T90573 | T28156 | arg1Of | decrease,to |
| R80657 | T76296 | T28156 | modOf | shown,to |
| R98509 | T21018 | T90573 | arg2Of | pressure,decrease |
| R15336 | T21018 | T38759 | arg1Of | pressure,blood |
| R35365 | T21018 | T30544 | arg1Of | pressure,in |
| R92187 | T98401 | T30544 | arg2Of | rats,in |
| R18068 | T98401 | T99198 | arg1Of | rats,hypertensive |
| R28884 | T90573 | T50903 | arg1Of | decrease,[ |
| R78348 | T33947 | T50903 | arg2Of | 33,[ |
| R16983 | T14997 | T50903 | arg3Of | ],[ |
| R11025 | T39838 | T50077 | arg1Of | decrease,Through |
| R25499 | T35438 | T50077 | arg2Of | up-regulation,Through |
| R59897 | T35438 | T34549 | arg1Of | up-regulation,the |
| R72877 | T35438 | T84846 | arg1Of | up-regulation,of |
| R88924 | T32352 | T84846 | arg2Of | and,of |
| R12153 | T82446 | T51616 | arg1Of | ACE2,"," |
| R51576 | T55154 | T51616 | arg2Of | E-cadherin,"," |
| R16601 | T51616 | T8679 | arg1Of | ",","," |
| R37157 | T45090 | T8679 | arg2Of | ABCB-1,"," |
| R94582 | T32352 | T32702 | arg1Of | and,"," |
| R31240 | T8679 | T32352 | arg1Of | ",",and |
| R83427 | T2901 | T32352 | arg2Of | IRF-8,and |
| R25441 | T39838 | T24097 | arg1Of | decrease,"," |
| R8936 | T97074 | T68802 | arg1Of | IRW,can |
| R16195 | T39838 | T68802 | arg2Of | decrease,can |
| R23820 | T97074 | T39838 | arg1Of | IRW,decrease |
| R90193 | T28168 | T39838 | arg2Of | and,decrease |
| R23718 | T50074 | T60149 | arg1Of | activity,RAS |
| R84268 | T50074 | T49953 | arg1Of | activity,"," |
| R5174 | T70369 | T49953 | arg2Of | hyperplasia,"," |
| R56950 | T20067 | T91445 | arg1Of | and,"," |
| R62126 | T49953 | T20067 | arg1Of | ",",and |
| R50828 | T51592 | T20067 | arg2Of | inflammation,and |
| R79137 | T51592 | T30801 | arg1Of | inflammation,vascular |
| R32916 | T20067 | T28168 | arg1Of | and,and |
| R9640 | T82201 | T28168 | arg2Of | regulation,and |
| R39252 | T82201 | T93235 | arg1Of | regulation,aid |
| R17282 | T82201 | T43180 | arg1Of | regulation,differential |
| R40689 | T82201 | T72254 | arg1Of | regulation,of |
| R2805 | T87852 | T72254 | arg2Of | leukocytes,of |
| R97116 | T84385 | T80434 | arg1Of | reduce,On |
| R66699 | T81543 | T80434 | arg2Of | hand,On |
| R49039 | T81543 | T8306 | arg1Of | hand,the |
| R80362 | T81543 | T52921 | arg1Of | hand,other |
| R33807 | T84385 | T20825 | arg1Of | reduce,"," |
| R69781 | T84385 | T78284 | arg1Of | reduce,by |
| R59552 | T59443 | T78284 | arg2Of | down-regulation,by |
| R42808 | T59443 | T10667 | arg1Of | down-regulation,the |
| R37642 | T59443 | T14412 | arg1Of | down-regulation,of |
| R60032 | T20179 | T14412 | arg2Of | molecules,of |
| R10382 | T20179 | T13570 | arg1Of | molecules,pro-inflammatory |
| R8517 | T59443 | T42843 | arg1Of | down-regulation,"," |
| R90023 | T59443 | T68303 | arg1Of | down-regulation,e.g. |
| R73050 | T59443 | T5913 | arg1Of | down-regulation,"," |
| R94229 | T22569 | T5913 | arg2Of | and,"," |
| R34146 | T53611 | T22569 | arg1Of | ICAM-1,and |
| R33352 | T86123 | T22569 | arg2Of | VCAM-1,and |
| R76335 | T84385 | T88206 | arg1Of | reduce,"," |
| R60787 | T14786 | T56782 | arg1Of | IRW,can |
| R45141 | T84385 | T56782 | arg2Of | reduce,can |
| R90684 | T14786 | T84385 | arg1Of | IRW,reduce |
| R50238 | T53586 | T84385 | arg2Of | recruitment,reduce |
| R32875 | T53586 | T54198 | arg1Of | recruitment,the |
| R63068 | T53586 | T18273 | arg1Of | recruitment,of |
| R40020 | T50471 | T18273 | arg2Of | and,of |
| R12291 | T25763 | T50471 | arg1Of | leukocytes,and |
| R70229 | T95815 | T50471 | arg2Of | inflammation,and |
| R62455 | T95815 | T39944 | arg1Of | inflammation,vascular |
| R23347 | T32229 | T37620 | arg1Of | Copper,might |
| R14025 | T49191 | T37620 | arg2Of | help,might |
| R59988 | T32229 | T49191 | arg1Of | Copper,help |
| R60777 | T77430 | T49191 | arg2Of | system,help |
| R87747 | T84428 | T49191 | arg3Of | combat,help |
| R43998 | T77430 | T32412 | arg1Of | system,the |
| R30131 | T77430 | T49707 | arg1Of | system,immune |
| R14331 | T84428 | T78509 | arg1Of | combat,to |
| R9364 | T77430 | T84428 | arg1Of | system,combat |
| R94399 | T25569 | T84428 | arg2Of | infections,combat |
| R89041 | T25569 | T52262 | arg1Of | infections,viral |
| R35214 | T86532 | T85825 | arg1Of | High-content,A |
| R88878 | T86532 | T37905 | arg1Of | High-content,of |
| R60596 | T38135 | T37905 | arg2Of | copper,of |
| R88306 | T86532 | T5313 | arg1Of | High-content,exists |
| R99347 | T5313 | T26683 | arg1Of | exists,in |
| R60659 | T88154 | T26683 | arg2Of | and,in |
| R82327 | T69996 | T88154 | arg1Of | eggs,and |
| R81333 | T28753 | T88154 | arg2Of | eggshells,and |
| R72922 | T88154 | T68700 | arg1Of | and,of |
| R79591 | T68554 | T68700 | arg2Of | birds,of |
| R53731 | T68554 | T82775 | arg1Of | birds,domestic |
| R74556 | T68835 | T12507 | arg1Of | contains,In |
| R67328 | T63866 | T12507 | arg2Of | particular,In |
| R76331 | T68835 | T96163 | arg1Of | contains,"," |
| R17857 | T93066 | T60294 | arg1Of | eggshell,the |
| R24501 | T93066 | T75912 | arg1Of | eggshell,of |
| R22893 | T52328 | T75912 | arg2Of | pigeon,of |
| R45343 | T52328 | T61958 | arg1Of | pigeon,( |
| R7081 | T94273 | T61958 | arg2Of | 0.29 μg/g,( |
| R48879 | T66624 | T61958 | arg3Of | ),( |
| R39708 | T94273 | T56156 | arg1Of | 0.29 μg/g,4 |
| R66187 | T94273 | T26914 | arg1Of | 0.29 μg/g,± |
| R85080 | T93066 | T87690 | arg1Of | eggshell,and |
| R94130 | T46042 | T87690 | arg2Of | egg,and |
| R57912 | T46042 | T47055 | arg1Of | egg,the |
| R76562 | T46042 | T48696 | arg1Of | egg,of |
| R84018 | T59365 | T48696 | arg2Of | quail,of |
| R11905 | T59365 | T45935 | arg1Of | quail,( |
| R9046 | T68174 | T45935 | arg2Of | ±,( |
| R2971 | T41203 | T45935 | arg3Of | ),( |
| R95143 | T43374 | T68174 | arg1Of | 4.67,± |
| R47055 | T58925 | T68174 | arg2Of | 1.08 μg/g,± |
| R31237 | T87690 | T68835 | arg1Of | and,contains |
| R82243 | T58590 | T68835 | arg2Of | concentrations,contains |
| R37940 | T58590 | T5139 | arg1Of | concentrations,high |
| R31078 | T58590 | T50194 | arg1Of | concentrations,of |
| R6977 | T95116 | T50194 | arg2Of | copper,of |
| R10854 | T68835 | T90276 | arg1Of | contains,[ |
| R6370 | T72554 | T90276 | arg2Of | 34,[ |
| R13035 | T34750 | T90276 | arg3Of | ],[ |
LitCovid-sample-PD-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 39-42 | http://purl.obolibrary.org/obo/MAT_0000213 | denotes | Egg |
| T11 | 167-172 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T12 | 167-172 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T13 | 405-409 | http://purl.obolibrary.org/obo/MAT_0000091 | denotes | hand |
| T14 | 661-665 | http://purl.obolibrary.org/obo/MAT_0000213 | denotes | eggs |
| T15 | 761-764 | http://purl.obolibrary.org/obo/MAT_0000213 | denotes | egg |
LitCovid-sample-PD-GO-BP-0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T49 | 224-234 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T50 | 332-344 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T51 | 366-376 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T52 | 423-433 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T53 | 548-560 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T54 | 608-624 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T185 | 167-172 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T186 | 244-254 | Body_part | denotes | E-cadherin | http://purl.org/sig/ont/fma/fma61792 |
| T187 | 380-390 | Body_part | denotes | leukocytes | http://purl.org/sig/ont/fma/fma62852 |
| T188 | 405-409 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T189 | 471-475 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T190 | 524-534 | Body_part | denotes | leukocytes | http://purl.org/sig/ont/fma/fma62852 |
| T191 | 584-597 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T183 | 306-317 | Disease | denotes | hyperplasia | http://purl.obolibrary.org/obo/MONDO_0005043 |
| T184 | 332-344 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T185 | 548-560 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T186 | 608-624 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
LitCovid-sample-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T44 | 224-234 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T45 | 332-344 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T46 | 366-376 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T47 | 423-433 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T48 | 548-560 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T49 | 608-624 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T44 | 224-234 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T45 | 332-344 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T46 | 366-376 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T47 | 423-433 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T48 | 548-560 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T49 | 608-624 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T213 | 0-38 | Sentence | denotes | 8 Eggs for increasing ACE2 and copper |
| T214 | 39-208 | Sentence | denotes | Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. |
| T215 | 209-391 | Sentence | denotes | Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. |
| T216 | 392-561 | Sentence | denotes | On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation. |
| T217 | 562-625 | Sentence | denotes | Copper might help the immune system to combat viral infections. |
| T218 | 626-698 | Sentence | denotes | A High-content of copper exists in eggs and eggshells of domestic birds. |
| T219 | 699-837 | Sentence | denotes | In particular, the eggshell of pigeon (4 ± 0.29 μg/g) and the egg of quail (4.67 ± 1.08 μg/g) contains high concentrations of copper [34]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32413736-26016560-48112979 | 204-206 | 26016560 | denotes | 33 |
| 32413736-18936883-48112980 | 833-835 | 18936883 | denotes | 34 |
| T22851 | 204-206 | 26016560 | denotes | 33 |
| T59191 | 833-835 | 18936883 | denotes | 34 |