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PMC:7172841 / 20179-21220 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T115 108-115 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T196 146-154 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T197 146-150 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T198 287-299 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T199 371-379 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T200 924-933 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T185 3-4 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T186 610-620 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T95 65-75 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T96 87-89 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T98 108-115 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T99 460-462 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T101 653-655 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T103 799-801 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T105 865-867 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T28 287-299 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T155 0-157 Sentence denotes As a next step, we measured circulating concentrations of TNF-α, interferon-γ (IFN-γ), IL-6, and C-reactive protein (CRP) in patients infected by SARS-CoV-2.
T156 158-300 Sentence denotes IFN-γ was below the limit of detection in all patients (data not shown), indicating that Th1 responses do not contribute to over-inflammation.
T157 301-446 Sentence denotes No differences of circulating TNF-α concentrations were found between COVID-19 patients at the three states of immune classification (Figure 4J).
T158 447-641 Sentence denotes In contrast, IL-6 and CRP concentrations were significantly higher among patients with immune dysregulation than among patients at an intermediate state of immune activation (Figures 4K and 4L).
T159 642-870 Sentence denotes Given that IL-6 was below the limit of detection in some patients with immune dysregulation, we divided them into two groups as follows: seven patients with IL-6 below the limit of detection and 14 patients with detectable IL-6.
T160 871-1041 Sentence denotes Their severity was similar given that SOFA score and pneumonia severity indexes were similar (p values of comparisons were 0.937 and 0.877, respectively; data not shown).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T76 534-554 Phenotype denotes immune dysregulation http://purl.obolibrary.org/obo/HP_0002958
T77 713-733 Phenotype denotes immune dysregulation http://purl.obolibrary.org/obo/HP_0002958
T78 924-933 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T603 58-63 PR:000000134 denotes TNF-α
T604 65-77 PR:000000017 denotes interferon-γ
T605 79-84 PR:000000017 denotes IFN-γ
T606 87-91 PR:000001393 denotes IL-6
T607 146-156 SP_7 denotes SARS-CoV-2
T608 158-163 PR:000000017 denotes IFN-γ
T609 331-336 PR:000000134 denotes TNF-α
T610 371-379 SP_7 denotes COVID-19
T611 412-418 UBERON:0002405 denotes immune
T612 460-464 PR:000001393 denotes IL-6
T613 534-540 UBERON:0002405 denotes immune
T614 541-554 GO:0065007 denotes dysregulation
T615 603-609 UBERON:0002405;GO:0006955 denotes immune
T616 610-620 GO:0006955 denotes activation
T617 653-657 PR:000001393 denotes IL-6
T618 713-719 UBERON:0002405 denotes immune
T619 720-733 GO:0065007 denotes dysregulation
T620 799-803 PR:000001393 denotes IL-6
T621 865-869 PR:000001393 denotes IL-6
T16441 2-15 GO:0065007 denotes a next step,
T31883 59-65 UBERON:0001969 denotes NF-α,
T77094 73-81 SP_7 denotes on-γ (IF
T99527 130-134 PR:000001393 denotes nts
T28022 140-150 GO:0010467 denotes ed by SARS
T24351 154-157 PR:000029150 denotes -2.
T74929 164-168 PR:000001889 denotes was
T46931 169-178 CL:0000576 denotes elow the
T14905 205-213 SP_7 denotes atients
T90612 214-220 UBERON:0001969 denotes data n
T22798 240-245 UBERON:0002405 denotes g tha
T25127 246-259 GO:0065007 denotes Th1 response
T87755 271-277 UBERON:0001969 denotes tribut
T23660 313-318 UBERON:0002405 denotes es of
T93288 400-404 PR:000001393 denotes e st
T38704 413-425 DG_35 denotes mmune classi
T60768 449-459 GO:0010467 denotes contrast,
T92597 463-466 PR:000029150 denotes 6 a
T91530 473-482 CL:0000576 denotes concentra
T73742 504-509 UBERON:0002405 denotes ly hi
T87416 510-523 GO:0065007 denotes her among pat
T12256 561-572 DG_35 denotes mong patien
T9459 634-644 CL:0000542 denotes nd 4L). Gi
T64763 645-650 UBERON:0000178 denotes en th
T60340 692-696 PR:000001393 denotes n so
T71836 721-725 PR:000001889 denotes ysre
T30333 726-735 CL:0000576 denotes ulation,
T21056 750-753 PR:000001004 denotes in
T60701 786-799 GO:0065007 denotes atients with
T44794 810-820 SP_7 denotes the limit
T48151 836-840 PR:000001393 denotes 14
T4688 873-878 UBERON:0001977 denotes eir s
T69065 890-894 PR:000001393 denotes simi
T73241 937-941 PR:000001889 denotes erit
T37140 942-951 CL:0000576 denotes indexes

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
822 58-63 Gene denotes TNF-α Gene:7124
823 65-77 Gene denotes interferon-γ Gene:3458
824 79-84 Gene denotes IFN-γ Gene:3458
825 87-91 Gene denotes IL-6 Gene:3569
826 97-115 Gene denotes C-reactive protein Gene:1401
827 117-120 Gene denotes CRP Gene:1401
828 158-163 Gene denotes IFN-γ Gene:3458
829 331-336 Gene denotes TNF-α Gene:7124
830 460-464 Gene denotes IL-6 Gene:3569
831 469-472 Gene denotes CRP Gene:1401
832 653-657 Gene denotes IL-6 Gene:3569
833 799-803 Gene denotes IL-6 Gene:3569
834 865-869 Gene denotes IL-6 Gene:3569
835 125-133 Species denotes patients Tax:9606
836 146-156 Species denotes SARS-CoV-2 Tax:2697049
837 204-212 Species denotes patients Tax:9606
838 380-388 Species denotes patients Tax:9606
839 520-528 Species denotes patients Tax:9606
840 566-574 Species denotes patients Tax:9606
841 699-707 Species denotes patients Tax:9606
842 785-793 Species denotes patients Tax:9606
843 840-848 Species denotes patients Tax:9606
844 134-142 Disease denotes infected MESH:D007239
845 287-299 Disease denotes inflammation MESH:D007249
846 371-379 Disease denotes COVID-19 MESH:C000657245
847 924-933 Disease denotes pneumonia MESH:D011014