PMC:7161517 / 8406-8758 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T42","span":{"begin":58,"end":62},"obj":"Body_part"},{"id":"T43","span":{"begin":112,"end":121},"obj":"Body_part"},{"id":"T44","span":{"begin":138,"end":149},"obj":"Body_part"},{"id":"T45","span":{"begin":150,"end":156},"obj":"Body_part"},{"id":"T46","span":{"begin":151,"end":153},"obj":"Body_part"},{"id":"T47","span":{"begin":159,"end":161},"obj":"Body_part"},{"id":"T48","span":{"begin":165,"end":173},"obj":"Body_part"},{"id":"T49","span":{"begin":190,"end":197},"obj":"Body_part"},{"id":"T50","span":{"begin":252,"end":256},"obj":"Body_part"}],"attributes":[{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T30","span":{"begin":252,"end":256},"obj":"Body_part"}],"attributes":[{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T45","span":{"begin":267,"end":289},"obj":"Disease"},{"id":"T46","span":{"begin":277,"end":289},"obj":"Disease"}],"attributes":[{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005149"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T97","span":{"begin":165,"end":173},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T98","span":{"begin":252,"end":256},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T99","span":{"begin":252,"end":256},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T100","span":{"begin":316,"end":318},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T101","span":{"begin":336,"end":338},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T84","span":{"begin":151,"end":153},"obj":"Chemical"},{"id":"T86","span":{"begin":159,"end":161},"obj":"Chemical"},{"id":"T88","span":{"begin":190,"end":197},"obj":"Chemical"}],"attributes":[{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A85","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A87","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T29","span":{"begin":218,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-sentences","denotations":[{"id":"T57","span":{"begin":0,"end":352},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":277,"end":289},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0000822"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T261","span":{"begin":42,"end":46},"obj":"G_3;PG_10;PR:000003622"},{"id":"T262","span":{"begin":47,"end":51},"obj":"PR:000036013"},{"id":"T263","span":{"begin":66,"end":76},"obj":"GO:0065007"},{"id":"T264","span":{"begin":81,"end":91},"obj":"GO:0010467"},{"id":"T265","span":{"begin":131,"end":136},"obj":"PR:000000134"},{"id":"T266","span":{"begin":159,"end":163},"obj":"PR:000001393"},{"id":"T267","span":{"begin":165,"end":173},"obj":"CL:0000576;PR:000002122"},{"id":"T268","span":{"begin":174,"end":199},"obj":"PR:000002122"},{"id":"T269","span":{"begin":205,"end":233},"obj":"PR:000000046"},{"id":"T270","span":{"begin":237,"end":244},"obj":"UBERON:0000948"},{"id":"T271","span":{"begin":252,"end":256},"obj":"UBERON:0002048"},{"id":"T272","span":{"begin":267,"end":276},"obj":"UBERON:0002048"},{"id":"T20825","span":{"begin":11,"end":16},"obj":"PR:000036013"},{"id":"T14954","span":{"begin":24,"end":28},"obj":"PR:000003622;G_3;PG_10"},{"id":"T39929","span":{"begin":50,"end":53},"obj":"PR:000001563"},{"id":"T49406","span":{"begin":106,"end":110},"obj":"G_3;PG_10;PR:000003622"},{"id":"T29031","span":{"begin":111,"end":115},"obj":"PR:000036013"},{"id":"T97645","span":{"begin":182,"end":187},"obj":"PR:000013883"},{"id":"T54224","span":{"begin":214,"end":218},"obj":"PR:000001251"},{"id":"T94906","span":{"begin":223,"end":227},"obj":"PR:000003622;G_3;PG_10"},{"id":"T80849","span":{"begin":241,"end":247},"obj":"PR:000036009"},{"id":"T57333","span":{"begin":259,"end":263},"obj":"PR:000001251"},{"id":"T66538","span":{"begin":287,"end":291},"obj":"PR:000003622;G_3;PG_10"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"LitCovid-PubTator","denotations":[{"id":"406","span":{"begin":42,"end":46},"obj":"Gene"},{"id":"407","span":{"begin":47,"end":53},"obj":"Gene"},{"id":"408","span":{"begin":131,"end":136},"obj":"Gene"},{"id":"409","span":{"begin":138,"end":157},"obj":"Gene"},{"id":"410","span":{"begin":159,"end":163},"obj":"Gene"},{"id":"411","span":{"begin":165,"end":199},"obj":"Gene"},{"id":"412","span":{"begin":205,"end":233},"obj":"Gene"},{"id":"424","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"425","span":{"begin":267,"end":289},"obj":"Disease"}],"attributes":[{"id":"A406","pred":"tao:has_database_id","subj":"406","obj":"Gene:70008"},{"id":"A407","pred":"tao:has_database_id","subj":"407","obj":"Gene:11727"},{"id":"A408","pred":"tao:has_database_id","subj":"408","obj":"Gene:7124"},{"id":"A409","pred":"tao:has_database_id","subj":"409","obj":"Gene:3552"},{"id":"A410","pred":"tao:has_database_id","subj":"410","obj":"Gene:3569"},{"id":"A411","pred":"tao:has_database_id","subj":"411","obj":"Gene:6347"},{"id":"A412","pred":"tao:has_database_id","subj":"412","obj":"Gene:7124"},{"id":"A424","pred":"tao:has_database_id","subj":"424","obj":"MESH:D005355"},{"id":"A425","pred":"tao:has_database_id","subj":"425","obj":"MESH:D006976"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}

{"project":"2_test","denotations":[{"id":"32305401-16024575-55252940","span":{"begin":316,"end":318},"obj":"16024575"},{"id":"32305401-19715669-55252941","span":{"begin":320,"end":322},"obj":"19715669"},{"id":"32305401-17098828-55252942","span":{"begin":324,"end":326},"obj":"17098828"},{"id":"32305401-21952934-55252943","span":{"begin":328,"end":330},"obj":"21952934"},{"id":"32305401-19246717-55252944","span":{"begin":332,"end":334},"obj":"19246717"},{"id":"32305401-19564552-55252945","span":{"begin":336,"end":338},"obj":"19564552"}],"text":"Other studies highlighted the role of the ACE2/Ang1-7/Mas axis in modulating the expression of pro-inflammatory cytokines, such as TNF-α, interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1, and transforming growth factor-β in cardiac and/or lung fibrosis, pulmonary hypertension, and vascular remodeling (36, 37, 38, 39, 40, 41) (Figure 1 )."}