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PMC:7160614 / 14329-18413 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
194 716-724 Disease denotes COVID-19 MESH:C000657245
195 734-742 Disease denotes COVID-19 MESH:C000657245
199 666-674 Species denotes patients Tax:9606
200 678-686 Disease denotes COVID-19 MESH:C000657245
201 695-703 Disease denotes COVID-19 MESH:C000657245
203 2181-2184 Chemical denotes GGO
209 3795-3813 Gene denotes C-reactive protein Gene:1401
210 2510-2518 Disease denotes COVID-19 MESH:C000657245
211 2528-2536 Disease denotes COVID-19 MESH:C000657245
212 3011-3020 Disease denotes Dry cough MESH:D003371
213 3056-3063 Disease denotes Fatigue MESH:D005221
217 2460-2468 Species denotes patients Tax:9606
218 2472-2480 Disease denotes COVID-19 MESH:C000657245
219 2489-2497 Disease denotes COVID-19 MESH:C000657245
225 24-32 Species denotes patients Tax:9606
226 50-58 Disease denotes COVID-19 MESH:C000657245
227 381-388 Disease denotes fatigue MESH:D005221
228 572-580 Disease denotes COVID-19 MESH:C000657245
229 608-616 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T23 393-409 Body_part denotes white blood cell http://purl.org/sig/ont/fma/fma62852
T24 405-409 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T25 2703-2708 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T26 2774-2779 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T27 2894-2899 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T28 3103-3109 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T29 3184-3188 Body_part denotes nose http://purl.org/sig/ont/fma/fma46472
T30 3217-3233 Body_part denotes White blood cell http://purl.org/sig/ont/fma/fma62852
T31 3229-3233 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T32 3285-3301 Body_part denotes White blood cell http://purl.org/sig/ont/fma/fma62852
T33 3297-3301 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T34 3418-3428 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T35 3476-3486 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T36 3606-3616 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T37 3667-3677 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T38 3806-3813 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T19 399-404 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T20 2070-2076 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T21 2703-2708 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T22 2774-2779 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T23 2894-2899 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T24 3103-3109 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T25 3184-3188 Body_part denotes nose http://purl.obolibrary.org/obo/UBERON_0000004
T26 3223-3228 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T27 3291-3296 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T61 50-58 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 572-580 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 608-616 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 678-686 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T65 695-703 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 716-724 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T67 734-742 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 2472-2480 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 2489-2497 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 2510-2518 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 2528-2536 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T72 3098-3109 Disease denotes Sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T73 3178-3188 Disease denotes Runny nose http://purl.obolibrary.org/obo/MONDO_0003014

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T80 80-82 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T81 194-196 http://purl.obolibrary.org/obo/CLO_0002861 denotes E3
T82 399-404 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T83 405-409 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T84 512-513 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T85 1744-1746 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T86 2013-2015 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T87 2048-2050 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T88 2070-2076 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T89 2157-2159 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T90 2404-2408 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T91 2426-2430 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T92 2560-2564 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T93 2560-2564 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T94 2578-2580 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T95 2599-2605 http://purl.obolibrary.org/obo/UBERON_0003100 denotes Female
T96 2703-2708 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T97 2703-2708 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T98 2774-2779 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T99 2774-2779 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T100 2894-2899 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T101 2894-2899 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T102 2894-2899 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T103 2894-2899 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T104 3034-3036 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T105 3076-3078 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T106 3184-3188 http://www.ebi.ac.uk/efo/EFO_0000828 denotes nose
T107 3223-3228 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T108 3229-3233 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T109 3291-3296 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T110 3297-3301 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T111 3364-3366 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T112 3553-3555 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T113 3965-3969 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T114 3987-3991 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T115 4014-4018 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T10 581-586 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T11 617-622 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T12 3806-3813 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T3 2833-2844 http://purl.obolibrary.org/obo/GO_0045333 denotes Respiration
T4 2833-2844 http://purl.obolibrary.org/obo/GO_0007585 denotes Respiration

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T15 381-388 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T16 1963-1981 Phenotype denotes Pleural thickening http://purl.obolibrary.org/obo/HP_0031944
T17 3011-3020 Phenotype denotes Dry cough http://purl.obolibrary.org/obo/HP_0031246
T18 3056-3063 Phenotype denotes Fatigue http://purl.obolibrary.org/obo/HP_0012378
T19 3098-3109 Phenotype denotes Sore throat http://purl.obolibrary.org/obo/HP_0033050
T20 3178-3188 Phenotype denotes Runny nose http://purl.obolibrary.org/obo/HP_0031417

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T121 0-205 Sentence denotes The differences between patients with and without COVID-19 for all 67 features (41 imaging and 26 critical clinical features) are shown in Tables 1 and 2 and the Supplementary Materials (Tables E3 and E4).
T122 206-353 Sentence denotes The differences between the primary cohort and validation cohort for the same features are shown in the Supplementary Materials (Tables E5 and E6).
T123 354-511 Sentence denotes All characteristics except fatigue and white blood cell count in the CR model presented no significant difference between the primary and validation cohorts.
T124 512-623 Sentence denotes A total of 1745 lesions were identified, with 1062 from the COVID-19 group and 683 from the non-COVID-19 group.
T125 624-703 Sentence denotes Table 1 Radiological semantic features of patients in COVID-19 and non-COVID-19
T126 704-759 Sentence denotes Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value
T127 760-778 Sentence denotes Number of pure GGO
T128 779-831 Sentence denotes   Total# 1.00 (0.00, 5.05) 3.50 (0.95, 8.05) 0.018b*
T129 832-894 Sentence denotes   Peripheral area# 1.00 (0.00, 4.05) 2.00 (0.00, 6.05) 0.032b*
T130 895-982 Sentence denotes   Central/both peripheral and central area# 0.00 (0.00, 0.00) 0.00 (0.00, 2.00) 0.001b*
T131 983-1002 Sentence denotes Number of mixed GGO
T132 1003-1055 Sentence denotes   Total# 1.00 (0.00, 3.05) 3.00 (1.00, 9.00) 0.001b*
T133 1056-1120 Sentence denotes   Peripheral area# 0.00 (0.00, 2.00) 2.50 (1.00, 6.00) < 0.001b*
T134 1121-1207 Sentence denotes   Central/both peripheral and central area# 0.00 (0.00, 1.05) 0.00 (0.00, 2.00) 0.657b
T135 1208-1237 Sentence denotes Total number of consolidation
T136 1238-1298 Sentence denotes   Consolidation# 1.00 (0.00, 3.00) 0.00 (0.00, 0.05) 0.001b*
T137 1299-1363 Sentence denotes   Pure solid nodules# 0.00 (0.00, 0.00) 0.00 (0.00, 0.00) 0.309b
T138 1364-1433 Sentence denotes   Solid nodules with GGO# 0.00 (0.00, 0.00) 0.00 (0.00, 1.00) 0.033b*
T139 1434-1457 Sentence denotes Total number of lesions
T140 1458-1520 Sentence denotes   Peripheral area# 5.00 (2.00, 9.05) 7.00 (2.00, 13.00) 0.112b
T141 1521-1579 Sentence denotes   Central area# 0.00 (0.00, 3.00) 0.00 (0.00, 1.05) 0.960b
T142 1580-1658 Sentence denotes   Both peripheral and central area# 0.00 (0.00, 2.00) 0.00 (0.00, 2.05) 0.582b
T143 1659-1697 Sentence denotes Interlobular septal thickening 0.009a*
T144 1698-1732 Sentence denotes   Negative 44 (66.67%) 31 (44.29%)
T145 1733-1767 Sentence denotes   Positive 22 (33.33%) 39 (55.71%)
T146 1768-1798 Sentence denotes Crazy paving pattern < 0.001a*
T147 1799-1833 Sentence denotes   Negative 60 (90.91%) 32 (45.71%)
T148 1834-1866 Sentence denotes   Positive 6 (9.09%) 38 (54.29%)
T149 1867-1893 Sentence denotes Tree-in-bud sign < 0.001a*
T150 1894-1928 Sentence denotes   Negative 37 (56.06%) 61 (87.14%)
T151 1929-1962 Sentence denotes   Positive 29 (43.94%) 9 (12.86%)
T152 1963-1989 Sentence denotes Pleural thickening 0.030a*
T153 1990-2024 Sentence denotes   Negative 46 (69.70%) 36 (51.43%)
T154 2025-2059 Sentence denotes   Positive 20 (30.30%) 34 (48.57%)
T155 2060-2110 Sentence denotes Offending vessel augmentation in lesions < 0.001a*
T156 2111-2145 Sentence denotes   Negative 55 (83.33%) 17 (24.29%)
T157 2146-2180 Sentence denotes   Positive 11 (16.67%) 53 (75.71%)
T158 2181-2207 Sentence denotes GGO ground-glass opacities
T159 2208-2351 Sentence denotes #Results are median with interquartile range in parentheses, and the remainder results are measurements with corresponding ratio in parentheses
T160 2352-2413 Sentence denotes *Data with statistical significance. pa: chi-square test, pb:
T161 2414-2430 Sentence denotes Student’s t test
T162 2431-2497 Sentence denotes Table 2 Clinical features of patients in COVID-19 and non-COVID-19
T163 2498-2553 Sentence denotes Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value
T164 2554-2557 Sentence denotes Sex
T165 2558-2596 Sentence denotes   Male# 43 (65.15%) 41 (58.57%) 0.430a
T166 2597-2630 Sentence denotes   Female# 23 (34.85%) 29 (41.43%)
T167 2631-2679 Sentence denotes   Age (years) 46.73 ± 25.00 42.93 ± 13.32 0.275b
T168 2680-2691 Sentence denotes Vital signs
T169 2692-2761 Sentence denotes   Systolic blood pressure (mmHg) 126.92 ± 23.07 127.07 ± 15.16 0.965b
T170 2762-2830 Sentence denotes   Diastolic blood pressure (mmHg) 77.74 ± 15.72 80.39 ± 10.51 0.254b
T171 2831-2891 Sentence denotes   Respiration rate (bpm) 25.20 ± 7.29 19.86 ± 1.90 < 0.001b*
T172 2892-2949 Sentence denotes   Heart rate (bpm) 101.59 ± 20.36 86.06 ± 13.34 < 0.001b*
T173 2950-3002 Sentence denotes   Temperature (°C) 37.61 ± 1.06 37.12 ± 0.83 0.003b*
T174 3003-3008 Sentence denotes Signs
T175 3009-3053 Sentence denotes   Dry cough# 56 (84.85%) 48 (68.57%) 0.025a*
T176 3054-3095 Sentence denotes   Fatigue# 8 (12.12%) 22 (31.43%) 0.007a*
T177 3096-3138 Sentence denotes   Sore throat# 6 (9.09%) 9 (12.86%) 0.483a
T178 3139-3175 Sentence denotes   Stuffy# 4 (6.06%) 2 (2.86%) 0.623a
T179 3176-3216 Sentence denotes   Runny nose# 3 (4.55%) 3 (4.29%) 0.731a
T180 3217-3284 Sentence denotes White blood cell count (× 109/L) 11.48 ± 5.36 5.27 ± 2.33 < 0.001b*
T181 3285-3326 Sentence denotes White blood cell count category < 0.001c*
T182 3327-3353 Sentence denotes   Low# 0 (0.00%) 2 (2.86%)
T183 3354-3387 Sentence denotes   Normal# 27 (40.91%) 63 (90.00%)
T184 3388-3417 Sentence denotes   High# 39 (59.09%) 5 (7.14%)
T185 3418-3475 Sentence denotes Lymphocyte count (× 109/L) 1.57 ± 1.33 1.25 ± 0.68 0.086b
T186 3476-3511 Sentence denotes Lymphocyte count category < 0.001c*
T187 3512-3542 Sentence denotes   Low# 24 (36.36%) 32 (45.71%)
T188 3543-3576 Sentence denotes   Normal# 35 (53.03%) 37 (52.86%)
T189 3577-3605 Sentence denotes   High# 7 (10.61%) 1 (1.43%)
T190 3606-3666 Sentence denotes Neutrophil count (× 109/L) 8.97 ± 4.90 3.53 ± 2.17 < 0.001b*
T191 3667-3702 Sentence denotes Neutrophil count category < 0.001c*
T192 3703-3730 Sentence denotes   Low# 3 (4.55%) 8 (11.43%)
T193 3731-3764 Sentence denotes   Normal# 23 (34.85%) 59 (84.29%)
T194 3765-3794 Sentence denotes   High# 40 (60.61%) 3 (4.29%)
T195 3795-3858 Sentence denotes C-reactive protein (mg/L) 69.30 ± 65.88 26.37 ± 30.97 < 0.001b*
T196 3859-3912 Sentence denotes Procalcitonin (ng/mL) 3.36 ± 8.98 0.26 ± 0.84 0.007b*
T197 3913-3974 Sentence denotes *Data with statistical significance. pa: chi-square test, pb:
T198 3975-3996 Sentence denotes Student’s t test. pc:
T199 3997-4018 Sentence denotes Kruskal-Wallis H test
T200 4019-4084 Sentence denotes #Results are measurements with corresponding ratio in parentheses