PMC:7127386 / 957-1294 JSONTXT

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Combinational therapy may help to reduce the effective concentration of compounds below the therapeutic plasma concentrations and provide better clinical benefits.\n\nHighlights\n• Remdesivir inhibits SARS-CoV-2 replication in Vero-E6 cells with EC50 at 23.15 μM.\n• Lopinavir but not ritonavir inhibits SARS-CoV-2 replication with EC50 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