. Combinational therapy may help to reduce the effective concentration of compounds below the therapeutic plasma concentrations and provide better clinical benefits.

Highlights
•  Remdesivir inhibits SARS-CoV-2 replication in Vero-E6 cells with EC50 at 23.15 μM.
•  Lopinavir but not ritonavir inhibits SARS-CoV-2 replication with EC50