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PMC:7118659 / 17014-18430 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T8 474-485 https://glytoucan.org/Structures/Glycans/G81533KY denotes Sialic acid
T9 500-511 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T10 654-665 https://glytoucan.org/Structures/Glycans/G81533KY denotes Sialic acid
T11 680-691 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T12 764-775 https://glytoucan.org/Structures/Glycans/G81533KY denotes Sialic acid
T13 918-929 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T102 334-349 Body_part denotes Heparan sulfate http://purl.org/sig/ont/fma/fma63023
T103 334-341 Body_part denotes Heparan http://purl.org/sig/ont/fma/fma67110
T104 392-395 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T105 442-450 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T106 641-644 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T107 781-784 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T108 792-801 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T109 1186-1190 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T110 1240-1247 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T111 1288-1295 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T112 1403-1410 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p76585s9 897-910 MPA denotes glycosylation
p76585s14 925-942 MPA denotes acid biosynthesis

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T104 519-527 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T105 747-755 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 1275-1283 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T216 8-13 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T217 118-123 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T218 786-791 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T219 811-812 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T220 846-847 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T221 1038-1040 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T222 1186-1190 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T223 1217-1225 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T224 1310-1320 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T225 1383-1393 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T184 80-91 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T185 293-304 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T186 334-349 Chemical denotes Heparan sulfate http://purl.obolibrary.org/obo/CHEBI_28815
T187 342-349 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T188 442-450 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T189 481-485 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T190 487-511 Chemical denotes O-acetylated sialic acid http://purl.obolibrary.org/obo/CHEBI_28879
T191 500-511 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T192 507-511 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T193 530-541 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T194 661-665 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T195 667-691 Chemical denotes O-acetylated sialic acid http://purl.obolibrary.org/obo/CHEBI_28879
T196 680-691 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T197 687-691 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T198 771-775 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T199 802-809 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T200 848-859 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T201 918-929 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T202 925-929 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T203 1240-1247 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T204 1288-1295 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T205 1403-1410 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T45 897-910 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T46 930-942 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 334-349 GlycoEpitope denotes Heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
532 250-266 Gene denotes Aminopeptidase N Gene:290
533 268-271 Gene denotes APN Gene:290
534 293-324 Gene denotes Angiotensin-converting enzyme 2 Gene:59272
535 326-330 Gene denotes ACE2 Gene:59272
536 530-561 Gene denotes Angiotensin-converting enzyme 2 Gene:59272
537 563-567 Gene denotes ACE2 Gene:59272
538 569-576 Gene denotes DC-SIGN Gene:30835
539 577-582 Gene denotes CD209 Gene:30835
540 584-592 Gene denotes DC-SIGNr Gene:10332
541 594-601 Gene denotes DC-SIGN Gene:30835
542 707-729 Gene denotes Dipeptidyl peptidase 4 Gene:1803
543 731-735 Gene denotes DPP4 Gene:1803
544 142-153 Species denotes Coronavirus Tax:11118
545 240-249 Species denotes HCoV-229E Tax:11137
546 283-292 Species denotes HCoV-NL63 Tax:277944
547 365-380 Species denotes Betacoronavirus Tax:694002
548 382-391 Species denotes HCoV-OC43 Tax:31631
549 519-527 Species denotes SARS-CoV Tax:694009
550 631-640 Species denotes HCoV-HKU1 Tax:290028
551 696-704 Species denotes MERS-CoV Tax:1335626
552 747-757 Species denotes SARS-CoV-2 Tax:2697049
553 764-775 Chemical denotes Sialic acid MESH:D019158
557 8-25 Species denotes Human coronavirus Tax:694448
558 27-31 Species denotes HCoV Tax:694448
559 80-91 Chemical denotes chloroquine MESH:D002738
561 786-791 Species denotes human Tax:9606
565 891-895 Gene denotes ACE2 Gene:59272
566 848-859 Chemical denotes Chloroquine MESH:D002738
567 918-929 Chemical denotes sialic acid MESH:D019158
574 1230-1235 Gene denotes spike Gene:43740568
575 1324-1335 Gene denotes cathepsin L Gene:1514
576 1368-1373 Gene denotes furin Gene:5045
577 1252-1265 Species denotes coronaviruses Tax:11118
578 1275-1283 Species denotes SARS-CoV Tax:694009
579 1345-1353 Species denotes MERS-CoV Tax:1335626

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T97 0-141 Sentence denotes Table 1 Human coronavirus (HCoV) receptors/co-receptors as possible targets for chloroquine-induced inhibition of the virus replication cycle
T98 142-221 Sentence denotes Coronavirus Receptora May also bind Replication cycle inhibited by chloroquineb
T99 222-238 Sentence denotes Alphacoronavirus
T100 239-281 Sentence denotes  HCoV-229E Aminopeptidase N (APN)/CD13 Yes
T101 282-333 Sentence denotes  HCoV-NL63 Angiotensin-converting enzyme 2 (ACE2) ?
T102 334-364 Sentence denotes Heparan sulfate proteoglycansc
T103 365-380 Sentence denotes Betacoronavirus
T104 381-517 Sentence denotes  HCoV-OC43 HLA class Id, IFN-inducible transmembrane (IFITM) proteins in endocytic vesiclese Sialic acid (O-acetylated sialic acid)f Yes
T105 518-629 Sentence denotes  SARS-CoV-1 Angiotensin-converting enzyme 2 (ACE2) DC-SIGN/CD209, DC-SIGNr, DC-SIGN-related lectin LSECting Yes
T106 630-694 Sentence denotes  HCoV-HKU1 HLA class Ih Sialic acid (O-acetylated sialic acid) ?
T107 695-745 Sentence denotes  MERS-CoV i Dipeptidyl peptidase 4 (DPP4)/CD26 Yes
T108 746-776 Sentence denotes  SARS-CoV-2 ACE2i Sialic acid?
T109 777-780 Sentence denotes Yes
T110 781-810 Sentence denotes HLA, human leukocyte antigen.
T111 811-845 Sentence denotes a Adapted from Graham et al. [91].
T112 846-943 Sentence denotes b Chloroquine could interfere with receptor (ACE2) glycosylation and/or sialic acid biosynthesis.
T113 944-980 Sentence denotes c According to Milewska et al. [92].
T114 981-1009 Sentence denotes d According to Collins [93].
T115 1010-1042 Sentence denotes e According to Zhao et al. [94].
T116 1043-1077 Sentence denotes f According to Vlasak et al. [95].
T117 1078-1111 Sentence denotes g According to Huang et al. [96].
T118 1112-1144 Sentence denotes h According to Chan et al. [97].
T119 1145-1416 Sentence denotes i It is worth noting that different host cell proteases are required to activate the spike (S) protein for coronaviruses, such as SARS-CoV-1 S protein that requires activation by cathepsin L [89], or MERS-CoV that requires furin-mediated activation of the S protein [98].

2_test

Id Subject Object Predicate Lexical cue
32171740-24217413-48148591 841-843 24217413 denotes 91
32171740-25187545-48148592 976-978 25187545 denotes 92
32171740-8505072-48148593 1005-1007 8505072 denotes 93
32171740-24753610-48148594 1038-1040 24753610 denotes 94
32171740-3380803-48148595 1073-1075 3380803 denotes 95
32171740-25926653-48148596 1107-1109 25926653 denotes 96
32171740-18987136-48148597 1140-1142 18987136 denotes 97
32171740-21435673-48148598 1337-1339 21435673 denotes 89
32171740-25288733-48148599 1412-1414 25288733 denotes 98
T82592 841-843 24217413 denotes 91
T9803 976-978 25187545 denotes 92
T63293 1005-1007 8505072 denotes 93
T56770 1038-1040 24753610 denotes 94
T98705 1073-1075 3380803 denotes 95
T76945 1107-1109 25926653 denotes 96
T10080 1140-1142 18987136 denotes 97
T19530 1337-1339 21435673 denotes 89
T61032 1412-1414 25288733 denotes 98