PMC:7103735 / 35554-36386 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T123","span":{"begin":500,"end":504},"obj":"Body_part"}],"attributes":[{"id":"A123","pred":"fma_id","subj":"T123","obj":"http://purl.org/sig/ont/fma/fma25056"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T366","span":{"begin":200,"end":208},"obj":"Disease"},{"id":"T367","span":{"begin":200,"end":204},"obj":"Disease"},{"id":"T368","span":{"begin":341,"end":345},"obj":"Disease"},{"id":"T369","span":{"begin":535,"end":543},"obj":"Disease"},{"id":"T370","span":{"begin":535,"end":539},"obj":"Disease"}],"attributes":[{"id":"A366","pred":"mondo_id","subj":"T366","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A367","pred":"mondo_id","subj":"T367","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A368","pred":"mondo_id","subj":"T368","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A369","pred":"mondo_id","subj":"T369","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A370","pred":"mondo_id","subj":"T370","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T409","span":{"begin":424,"end":431},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T410","span":{"begin":607,"end":613},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"LitCovid-sentences","denotations":[{"id":"T303","span":{"begin":0,"end":50},"obj":"Sentence"},{"id":"T304","span":{"begin":51,"end":163},"obj":"Sentence"},{"id":"T305","span":{"begin":164,"end":270},"obj":"Sentence"},{"id":"T306","span":{"begin":271,"end":432},"obj":"Sentence"},{"id":"T307","span":{"begin":433,"end":518},"obj":"Sentence"},{"id":"T308","span":{"begin":519,"end":697},"obj":"Sentence"},{"id":"T309","span":{"begin":698,"end":832},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"2_test","denotations":[{"id":"32172672-26269185-27782258","span":{"begin":266,"end":268},"obj":"26269185"},{"id":"32172672-22993147-27782259","span":{"begin":470,"end":472},"obj":"22993147"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1049","span":{"begin":0,"end":4},"obj":"Species"},{"id":"1050","span":{"begin":200,"end":208},"obj":"Species"},{"id":"1051","span":{"begin":213,"end":221},"obj":"Species"},{"id":"1052","span":{"begin":535,"end":543},"obj":"Species"},{"id":"1053","span":{"begin":548,"end":556},"obj":"Species"},{"id":"1054","span":{"begin":607,"end":613},"obj":"Species"},{"id":"1055","span":{"begin":280,"end":284},"obj":"Species"},{"id":"1056","span":{"begin":441,"end":445},"obj":"Species"},{"id":"1057","span":{"begin":664,"end":668},"obj":"Species"}],"attributes":[{"id":"A1049","pred":"tao:has_database_id","subj":"1049","obj":"Tax:11118"},{"id":"A1050","pred":"tao:has_database_id","subj":"1050","obj":"Tax:694009"},{"id":"A1051","pred":"tao:has_database_id","subj":"1051","obj":"Tax:1335626"},{"id":"A1052","pred":"tao:has_database_id","subj":"1052","obj":"Tax:694009"},{"id":"A1053","pred":"tao:has_database_id","subj":"1053","obj":"Tax:1335626"},{"id":"A1054","pred":"tao:has_database_id","subj":"1054","obj":"Tax:9606"},{"id":"A1055","pred":"tao:has_database_id","subj":"1055","obj":"Tax:277944"},{"id":"A1056","pred":"tao:has_database_id","subj":"1056","obj":"Tax:277944"},{"id":"A1057","pred":"tao:has_database_id","subj":"1057","obj":"Tax:277944"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}

{"project":"MyTest","denotations":[{"id":"32172672-26269185-27782258","span":{"begin":266,"end":268},"obj":"26269185"},{"id":"32172672-22993147-27782259","span":{"begin":470,"end":472},"obj":"22993147"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"CoVs are believed to have existed for \u003e6000 years. Molecular clock analysis enables us to deduce the time of emergence or cross-species transmission of some HCoVs. Surprisingly, the highly pathogenic SARS-CoV and MERS-CoV are thought to emerge in the last 30 years [56]. Although NL63 and HKU1 of low pathogenicity were isolated in the post-SARS era, their time of emergence was earlier than the other two highly pathogenic viruses. Whereas NL63 emerged \u003e500 years ago [57], the origin of HKU1 dated back to the 1950s. In other words, SARS-CoV and MERS-CoV represent newcomers that are striving to adapt to humans, whereas other community-acquired HCoVs including NL63 and HKU1 are better adapted. The results of molecular dating of HCoVs suggest that attenuation might be favoured during evolution when host adaptation takes place."}