PMC:7074424 / 24386-24893
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
562 | 30-35 | Chemical | denotes | metal | MESH:D008670 |
563 | 111-117 | Chemical | denotes | 3CLpro | |
564 | 184-201 | Chemical | denotes | arylboronic acids | |
565 | 203-223 | Chemical | denotes | quinolinecarboxylate | |
566 | 237-257 | Chemical | denotes | thiophenecarboxylate | |
567 | 263-278 | Chemical | denotes | phthalhydrazide | |
568 | 291-304 | Chemical | denotes | ketoglutamine | |
569 | 323-333 | Chemical | denotes | flavonoids | MESH:D005419 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32201449-24080461-47217125 | 21-23 | 24080461 | denotes | 79 |
32201449-15788388-47217126 | 119-121 | 15788388 | denotes | 77 |
32201449-15788388-47217127 | 314-316 | 15788388 | denotes | 77 |
32201449-31724441-47217128 | 369-371 | 31724441 | denotes | 75 |
32201449-31585653-47217129 | 417-419 | 31585653 | denotes | 81 |
T645 | 21-23 | 24080461 | denotes | 79 |
T37277 | 119-121 | 15788388 | denotes | 77 |
T90937 | 314-316 | 15788388 | denotes | 77 |
T96138 | 369-371 | 31724441 | denotes | 75 |
T58881 | 417-419 | 31585653 | denotes | 81 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T754 | 36-46 | MOP:0000779 | denotes | conjugated |
T753 | 66-75 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
T752 | 141-150 | CHEBI:36357;CHEBI:36357 | denotes | molecules |
T751 | 166-175 | CHEBI:35222;CHEBI:35222 | denotes | inhibitor |
T750 | 184-195 | CHEBI:28619;CHEBI:28619 | denotes | arylboronic |
T749 | 196-201 | CHEBI:30956;CHEBI:30956 | denotes | acids |
T748 | 203-223 | CHEBI:15854;CHEBI:15854 | denotes | quinolinecarboxylate |
T747 | 237-257 | CHEBI:18022;CHEBI:18022 | denotes | thiophenecarboxylate |
T746 | 323-333 | CHEBI:47916;CHEBI:47916 | denotes | flavonoids |
T745 | 460-468 | CHEBI:36357;CHEBI:36357 | denotes | molecule |
T744 | 469-478 | CHEBI:35222;CHEBI:35222 | denotes | inhibitor |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T259 | 94-102 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T260 | 384-387 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T261 | 407-415 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T262 | 421-422 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T290 | 51-65 | Chemical | denotes | peptidomimetic | http://purl.obolibrary.org/obo/CHEBI_63175 |
T291 | 141-150 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
T292 | 166-175 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T293 | 196-201 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T294 | 323-333 | Chemical | denotes | flavonoids | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
T296 | 388-406 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
T298 | 397-406 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T299 | 460-468 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
T300 | 469-478 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T301 | 504-506 | Chemical | denotes | ID | http://purl.obolibrary.org/obo/CHEBI_141439 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T62 | 388-415 | http://purl.obolibrary.org/obo/GO_0030414 | denotes | protease inhibitor activity |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T146 | 0-507 | Sentence | denotes | 6.2 μM) is reported.[79] Some metal-conjugated and peptidomimetic compounds showed inhibitory activity against 3CLpro.[77] Some of the small molecules also act as an inhibitor that is arylboronic acids, quinolinecarboxylate derivatives, thiophenecarboxylate, and phthalhydrazide-substituted ketoglutamine analogs.[77] Some flavonoids are also reported to inhibit Mpro.[75] GC376 also has protease inhibitor activity.[81] A crystal structure of Mpro with small molecule inhibitor N3 is also reported (PDB ID: |