PMC:7074424 / 21376-21845
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 476 | 275-284 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 477 | 373-376 | Species | denotes | CoV | Tax:11118 |
| 478 | 407-410 | Species | denotes | COV | Tax:11118 |
| 480 | 411-415 | Species | denotes | OC43 | Tax:31631 |
| 488 | 175-237 | Chemical | denotes | N-(6-oxo-5,6-dihydrophenanthridine-2-yl) (N, N dimethyl amino) | |
| 489 | 239-243 | Chemical | denotes | PJ34 | MESH:C434926 |
| 490 | 307-311 | Chemical | denotes | PJ34 | MESH:C434926 |
| 491 | 437-441 | Chemical | denotes | PJ34 | MESH:C434926 |
| 498 | 77-80 | CellLine | denotes | LM9 | CVCL:5998 |
| 499 | 83-86 | CellLine | denotes | LM7 | CVCL:0515 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32201449-24564608-47217104 | 112-114 | 24564608 | denotes | 26 |
| 32201449-24564608-47217105 | 292-294 | 24564608 | denotes | 26 |
| 32201449-24564608-47217106 | 378-380 | 24564608 | denotes | 26 |
| T60843 | 112-114 | 24564608 | denotes | 26 |
| T45276 | 292-294 | 24564608 | denotes | 26 |
| T26983 | 378-380 | 24564608 | denotes | 26 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T662 | 37-44 | GO:0032991 | denotes | complex |
| T661 | 125-133 | CHEBI:36357;CHEBI:36357 | denotes | molecule |
| T660 | 175-176 | CHEBI:7586;CHEBI:7586 | denotes | N |
| T659 | 176-177 | CHEBI:82321;CHEBI:82321 | denotes | - |
| T658 | 177-180 | CHEBI:75508;CHEBI:75508 | denotes | (6- |
| T657 | 180-183 | CHEBI:46629;CHEBI:46629 | denotes | oxo |
| T656 | 183-186 | CHEBI:75508;CHEBI:75508 | denotes | -5, |
| T655 | 186-209 | CHEBI:53233;CHEBI:53233 | denotes | 6-dihydrophenanthridine |
| T654 | 209-210 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T653 | 210-214 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl |
| T652 | 331-337 | SO:0001026 | denotes | genome |
| T651 | 350-361 | GO:0006260 | denotes | replication |
| T650 | 427-436 | CHEBI:35222;CHEBI:35222 | denotes | inhibitor |
| T649 | 442-449 | GO:0032991 | denotes | complex |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T236 | 331-337 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T114 | 315-318 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T116 | 418-421 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T248 | 125-133 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T249 | 180-183 | Chemical | denotes | oxo | http://purl.obolibrary.org/obo/CHEBI_46629 |
| T250 | 222-230 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T252 | 231-236 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T253 | 427-436 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T254 | 466-468 | Chemical | denotes | ID | http://purl.obolibrary.org/obo/CHEBI_141439 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T127 | 0-469 | Sentence | denotes | Three-dimensional structure with all complex can see from PDB that is 4LMC, 4LM9, 4LM7, and 4LI4, respectively.[26] One such molecule which was designed with this strategy is N-(6-oxo-5,6-dihydrophenanthridine-2-yl) (N, N dimethyl amino) (PJ34), which was designed using the HCoV-OC43 model.[26] Binding of PJ34 on NTD affects the genome binding and replication process of CoV.[26] The crystal structure of COV-OC43 N-NTD with inhibitor PJ34 complex is given in PDB ID: |