PMC:7074424 / 21376-21845
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7074424","sourcedb":"PMC","sourceid":"7074424","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7074424","text":"Three-dimensional structure with all complex can see from PDB that is 4LMC, 4LM9, 4LM7, and 4LI4, respectively.[26] One such molecule which was designed with this strategy is N-(6-oxo-5,6-dihydrophenanthridine-2-yl) (N, N dimethyl amino) (PJ34), which was designed using the HCoV-OC43 model.[26] Binding of PJ34 on NTD affects the genome binding and replication process of CoV.[26] The crystal structure of COV-OC43 N-NTD with inhibitor PJ34 complex is given in PDB 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