PMC:7039714 / 1374-3785 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7039714","sourcedb":"PMC","sourceid":"7039714","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7039714","text":"CASE REPORT\n\nCase 1\nA 35-year-old man presented with fever for 3 days and cough for 2 days and was admitted to the emergency department of Jiangxi Provincial People's Hospital. The patient had a history of good physical health with no underlying diseases but had returned to Nanchang, Jiangxi Province, from Wuhan 1 week before. Physical examination showed fever, with a body temperature of 38.7℃, and the laboratory examination results showed a normal leukocyte count (5520/µL), increased neutrophils (76.2%), decreased lymphocytes (16.1%), elevated glucose (7.4 mmol/L), and elevated C-reactive protein (14.00 mg/L). The patient tested negative for eight common respiratory pathogens, which were respiratory syncytial virus, adenovirus, influenza A virus, Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila, parainfluenza virus, and influenza B virus, and the influenza A antigen screening was also negative. Finally, he was diagnosed with 2019-nCoV based on the real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample.\nCT showed multiple regions of patchy consolidation and ground-glass opacities with indistinct border in both lungs. The lesions were distributed along the bronchial bundles or within the subpleural lung regions (Fig. 1). Neither pleural effusion nor lymphadenopathy was found.\n\nCase 2\nA 39-year-old man presenting with fever and throat discomfort for 2 days was admitted to Jiangxi Provincial People's Hospital fever clinic. He had a history of good physical health and no underlying diseases. Although the patient had not visited Wuhan recently, he had a history of contact with the patient described in Case 1. Physical examination showed fever, with a temperature of 39.3℃, and laboratory examination results demonstrated a normal leukocyte count (5320/µL), normal neutrophils (67.6%), normal lymphocytes (24.5%), decreased aspartate aminotransferase (14 IU/L), elevated glucose (6.8 mmol/L), and normal CRP (4.00 mg/L). Finally, he was diagnosed with 2019-nCoV based on the rRT-PCR analysis of a sputum sample.\nCT imaging showed small ill-defined ground-glass opacities in both lower lung lobes. The lesion in the left lower lobe was located in the subpleural region while the one in the right lower lobe was distributed along the bundles (Fig. 2). Neither pleural effusion nor lymphadenopathy was 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