PMC:7033698 / 9182-10044 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T76","span":{"begin":309,"end":313},"obj":"Body_part"},{"id":"T77","span":{"begin":329,"end":332},"obj":"Body_part"},{"id":"T78","span":{"begin":387,"end":392},"obj":"Body_part"},{"id":"T79","span":{"begin":411,"end":416},"obj":"Body_part"},{"id":"T80","span":{"begin":441,"end":444},"obj":"Body_part"},{"id":"T81","span":{"begin":597,"end":602},"obj":"Body_part"},{"id":"T82","span":{"begin":683,"end":690},"obj":"Body_part"},{"id":"T83","span":{"begin":709,"end":714},"obj":"Body_part"}],"attributes":[{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"How the three bat CoV viruses obtain those inserts remains unknown. For any virus to obtain additional insert sequences from other organisms, it requires that it has direct interactions with other organisms, most likely through homologous or non-homologous recombination [11]. For bat CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible. On the contrary, these motifs are widely present in various mammalian cells and so it will be more likely for bat CoV viruses to gain those motifs from the genomes of their infected cells if recombination indeed occurs. However, extensive studies of more CoV viruses in wild and domestic animals are warranted to address this question."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T84","span":{"begin":14,"end":17},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T85","span":{"begin":22,"end":29},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T86","span":{"begin":76,"end":81},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T87","span":{"begin":131,"end":140},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T88","span":{"begin":131,"end":140},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T89","span":{"begin":162,"end":165},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T90","span":{"begin":197,"end":206},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T91","span":{"begin":197,"end":206},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T92","span":{"begin":272,"end":274},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T93","span":{"begin":281,"end":284},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T94","span":{"begin":289,"end":296},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T95","span":{"begin":309,"end":313},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T96","span":{"begin":357,"end":364},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T97","span":{"begin":387,"end":392},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T98","span":{"begin":411,"end":416},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T99","span":{"begin":421,"end":424},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T100","span":{"begin":429,"end":436},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T101","span":{"begin":597,"end":602},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T102","span":{"begin":637,"end":640},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T103","span":{"begin":645,"end":652},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T104","span":{"begin":709,"end":714},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T105","span":{"begin":786,"end":793},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T106","span":{"begin":815,"end":822},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"}],"text":"How the three bat CoV viruses obtain those inserts remains unknown. For any virus to obtain additional insert sequences from other organisms, it requires that it has direct interactions with other organisms, most likely through homologous or non-homologous recombination [11]. For bat CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible. On the contrary, these motifs are widely present in various mammalian cells and so it will be more likely for bat CoV viruses to gain those motifs from the genomes of their infected cells if recombination indeed occurs. However, extensive studies of more CoV viruses in wild and domestic animals are warranted to address this question."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":246,"end":270},"obj":"http://purl.obolibrary.org/obo/GO_0035825"},{"id":"T2","span":{"begin":485,"end":493},"obj":"http://purl.obolibrary.org/obo/GO_0015297"}],"text":"How the three bat CoV viruses obtain those inserts remains unknown. For any virus to obtain additional insert sequences from other organisms, it requires that it has direct interactions with other organisms, most likely through homologous or non-homologous recombination [11]. For bat CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible. On the contrary, these motifs are widely present in various mammalian cells and so it will be more likely for bat CoV viruses to gain those motifs from the genomes of their infected cells if recombination indeed occurs. However, extensive studies of more CoV viruses in wild and domestic animals are warranted to address this question."}

{"project":"LitCovid-sentences","denotations":[{"id":"T76","span":{"begin":0,"end":67},"obj":"Sentence"},{"id":"T77","span":{"begin":68,"end":276},"obj":"Sentence"},{"id":"T78","span":{"begin":277,"end":393},"obj":"Sentence"},{"id":"T79","span":{"begin":394,"end":526},"obj":"Sentence"},{"id":"T80","span":{"begin":527,"end":746},"obj":"Sentence"},{"id":"T81","span":{"begin":747,"end":862},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"How the three bat CoV viruses obtain those inserts remains unknown. For any virus to obtain additional insert sequences from other organisms, it requires that it has direct interactions with other organisms, most likely through homologous or non-homologous recombination [11]. For bat CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible. On the contrary, these motifs are widely present in various mammalian cells and so it will be more likely for bat CoV viruses to gain those motifs from the genomes of their infected cells if recombination indeed occurs. However, extensive studies of more CoV viruses in wild and domestic animals are warranted to address this question."}

{"project":"LitCovid-PubTator","denotations":[{"id":"265","span":{"begin":18,"end":21},"obj":"Species"},{"id":"266","span":{"begin":285,"end":288},"obj":"Species"},{"id":"267","span":{"begin":329,"end":334},"obj":"Species"},{"id":"268","span":{"begin":425,"end":428},"obj":"Species"},{"id":"269","span":{"begin":441,"end":446},"obj":"Species"},{"id":"270","span":{"begin":587,"end":596},"obj":"Species"},{"id":"271","span":{"begin":641,"end":644},"obj":"Species"},{"id":"272","span":{"begin":782,"end":785},"obj":"Species"},{"id":"273","span":{"begin":700,"end":708},"obj":"Disease"}],"attributes":[{"id":"A265","pred":"tao:has_database_id","subj":"265","obj":"Tax:11118"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"Tax:11118"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"Tax:11676"},{"id":"A268","pred":"tao:has_database_id","subj":"268","obj":"Tax:11118"},{"id":"A269","pred":"tao:has_database_id","subj":"269","obj":"Tax:11676"},{"id":"A270","pred":"tao:has_database_id","subj":"270","obj":"Tax:9606"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"Tax:11118"},{"id":"A272","pred":"tao:has_database_id","subj":"272","obj":"Tax:11118"},{"id":"A273","pred":"tao:has_database_id","subj":"273","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"How the three bat CoV viruses obtain those inserts remains unknown. For any virus to obtain additional insert sequences from other organisms, it requires that it has direct interactions with other organisms, most likely through homologous or non-homologous recombination [11]. For bat CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible. On the contrary, these motifs are widely present in various mammalian cells and so it will be more likely for bat CoV viruses to gain those motifs from the genomes of their infected cells if recombination indeed occurs. However, extensive studies of more CoV viruses in wild and domestic animals are warranted to address this question."}