PMC:3649690 / 11930-12487 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3649690","sourcedb":"PMC","sourceid":"3649690","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3649690","text":"6. Neurogenic Hypothesis of Depression\nAs noted earlier, neurogenesis in the adult hippocampus is seen across a variety of species, including humans [7]. Adult hippocampal neurogenesis has been hypothesized to play a potentially important role on the pathology and successful treatment of depression. A neurogenic hypothesis of depression has been postulated, which suggests that reduced adult hippocampal neurogenesis may underlie the pathoetiology of depression, while antidepressant efficacy depends on the upregulation of hippocampal neurogenesis [58].\n","divisions":[{"label":"Title","span":{"begin":0,"end":38}}],"tracks":[{"project":"NEUROSES","denotations":[{"id":"T303","span":{"begin":239,"end":243},"obj":"CHEBI_50906"},{"id":"T304","span":{"begin":380,"end":387},"obj":"PATO_0001997"},{"id":"T305","span":{"begin":471,"end":485},"obj":"CHEBI_35469"},{"id":"T306","span":{"begin":289,"end":299},"obj":"PM3425"},{"id":"T307","span":{"begin":328,"end":338},"obj":"PM3425"},{"id":"T308","span":{"begin":453,"end":463},"obj":"PM3425"},{"id":"T309","span":{"begin":289,"end":299},"obj":"PM3425"},{"id":"T310","span":{"begin":328,"end":338},"obj":"PM3425"},{"id":"T311","span":{"begin":453,"end":463},"obj":"PM3425"}],"attributes":[{"subj":"T303","pred":"source","obj":"NEUROSES"},{"subj":"T304","pred":"source","obj":"NEUROSES"},{"subj":"T305","pred":"source","obj":"NEUROSES"},{"subj":"T306","pred":"source","obj":"NEUROSES"},{"subj":"T307","pred":"source","obj":"NEUROSES"},{"subj":"T308","pred":"source","obj":"NEUROSES"},{"subj":"T309","pred":"source","obj":"NEUROSES"},{"subj":"T310","pred":"source","obj":"NEUROSES"},{"subj":"T311","pred":"source","obj":"NEUROSES"}]},{"project":"2_test","denotations":[{"id":"23691371-10889528-75337620","span":{"begin":552,"end":554},"obj":"10889528"}],"attributes":[{"subj":"23691371-10889528-75337620","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NEUROSES","color":"#ece793","default":true},{"id":"2_test","color":"#cd93ec"}]}]}}