PMC:3649690 / 11930-12487 JSONTXT

{"project":"NEUROSES","denotations":[{"id":"T303","span":{"begin":239,"end":243},"obj":"CHEBI_50906"},{"id":"T304","span":{"begin":380,"end":387},"obj":"PATO_0001997"},{"id":"T305","span":{"begin":471,"end":485},"obj":"CHEBI_35469"},{"id":"T306","span":{"begin":289,"end":299},"obj":"PM3425"},{"id":"T307","span":{"begin":328,"end":338},"obj":"PM3425"},{"id":"T308","span":{"begin":453,"end":463},"obj":"PM3425"},{"id":"T309","span":{"begin":289,"end":299},"obj":"PM3425"},{"id":"T310","span":{"begin":328,"end":338},"obj":"PM3425"},{"id":"T311","span":{"begin":453,"end":463},"obj":"PM3425"}],"text":"6. Neurogenic Hypothesis of Depression\nAs noted earlier, neurogenesis in the adult hippocampus is seen across a variety of species, including humans [7]. Adult hippocampal neurogenesis has been hypothesized to play a potentially important role on the pathology and successful treatment of depression. A neurogenic hypothesis of depression has been postulated, which suggests that reduced adult hippocampal neurogenesis may underlie the pathoetiology of depression, while antidepressant efficacy depends on the upregulation of hippocampal neurogenesis [58].\n"}

{"project":"2_test","denotations":[{"id":"23691371-10889528-75337620","span":{"begin":552,"end":554},"obj":"10889528"}],"text":"6. Neurogenic Hypothesis of Depression\nAs noted earlier, neurogenesis in the adult hippocampus is seen across a variety of species, including humans [7]. Adult hippocampal neurogenesis has been hypothesized to play a potentially important role on the pathology and successful treatment of depression. A neurogenic hypothesis of depression has been postulated, which suggests that reduced adult hippocampal neurogenesis may underlie the pathoetiology of depression, while antidepressant efficacy depends on the upregulation of hippocampal neurogenesis [58].\n"}