PMC:3586680 / 693-1083
Annnotations
test3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T78 | 295-298 | Protein | denotes | p53 |
T77 | 252-256 | Protein | denotes | WWOX |
T76 | 219-223 | Protein | denotes | WWOX |
T75 | 166-169 | Protein | denotes | p53 |
T74 | 100-104 | Protein | denotes | WWOX |
T73 | 92-95 | Protein | denotes | p53 |
T72 | 29-32 | Protein | denotes | p53 |
T71 | 0-4 | Binding | denotes | bind |
T58 | 295-298 | Protein | denotes | p53 |
T57 | 252-256 | Protein | denotes | WWOX |
T56 | 219-223 | Protein | denotes | WWOX |
T55 | 166-169 | Protein | denotes | p53 |
T54 | 100-104 | Protein | denotes | WWOX |
T53 | 92-95 | Protein | denotes | p53 |
T52 | 29-32 | Protein | denotes | p53 |
R8 | T72 | T71 | themeOf | p53,bind |
testone
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T40 | 0-4 | Binding | denotes | bind |
T36 | 295-298 | Protein | denotes | p53 |
T35 | 252-256 | Protein | denotes | WWOX |
T34 | 219-223 | Protein | denotes | WWOX |
T33 | 166-169 | Protein | denotes | p53 |
T32 | 100-104 | Protein | denotes | WWOX |
T31 | 92-95 | Protein | denotes | p53 |
T30 | 29-32 | Protein | denotes | p53 |
R3 | T30 | T40 | themeOf | p53,bind |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T496 | 310-320 | Negative_regulation | denotes | deficiency |
T495 | 295-298 | Protein | denotes | p53 |
T494 | 184-192 | Regulation | denotes | modulate |
T493 | 219-223 | Protein | denotes | WWOX |
T492 | 166-169 | Protein | denotes | p53 |
T491 | 100-104 | Protein | denotes | WWOX |
T490 | 92-95 | Protein | denotes | p53 |
T489 | 0-4 | Binding | denotes | bind |
T488 | 0-4 | Binding | denotes | bind |
T487 | 29-32 | Protein | denotes | p53 |
R245 | T487 | T489 | themeOf | p53,bind |
R246 | T492 | T494 | causeOf | p53,modulate |
R247 | T493 | T494 | themeOf | WWOX,modulate |
R248 | T495 | T496 | themeOf | p53,deficiency |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T729 | 383-384 | . | denotes | . |
T728 | 378-383 | NN | denotes | death |
T727 | 373-377 | NN | denotes | cell |
T726 | 369-372 | NNP | denotes | GBM |
T725 | 362-368 | VB | denotes | induce |
T724 | 358-361 | CC | denotes | and |
T723 | 347-357 | NN | denotes | resistance |
T722 | 343-346 | NNP | denotes | TMZ |
T721 | 334-342 | VB | denotes | overcome |
T720 | 331-333 | TO | denotes | to |
T719 | 324-330 | VBN | denotes | needed |
T718 | 321-323 | VBZ | denotes | is |
T717 | 310-320 | NN | denotes | deficiency |
T716 | 299-309 | JJ | denotes | functional |
T715 | 295-298 | NN | denotes | p53 |
T713 | 283-288 | NNS | denotes | drugs |
T712 | 271-282 | JJ | denotes | therapeutic |
T711 | 268-270 | IN | denotes | by |
T710 | 257-267 | NN | denotes | activation |
T709 | 252-256 | NNP | denotes | WWOX |
T708 | 241-251 | VBG | denotes | triggering |
T707 | 236-240 | IN | denotes | that |
T706 | 228-235 | VBP | denotes | propose |
T705 | 225-227 | PRP | denotes | We |
T704 | 223-224 | . | denotes | . |
T703 | 219-223 | NNP | denotes | WWOX |
T702 | 216-218 | IN | denotes | of |
T701 | 207-215 | NN | denotes | function |
T700 | 197-206 | JJ | denotes | apoptotic |
T699 | 193-196 | DT | denotes | the |
T698 | 184-192 | VBP | denotes | modulate |
T697 | 182-183 | , | denotes | , |
T696 | 174-182 | NNS | denotes | isoforms |
T695 | 171-173 | CC | denotes | or |
T694 | 169-170 | , | denotes | , |
T693 | 166-169 | NN | denotes | p53 |
T692 | 159-165 | JJ | denotes | mutant |
T691 | 155-158 | CC | denotes | and |
T690 | 150-154 | NN | denotes | type |
T689 | 145-149 | JJ | denotes | wild |
T688 | 140-144 | WDT | denotes | that |
T687 | 130-139 | NNS | denotes | scenarios |
T686 | 120-129 | JJ | denotes | potential |
T685 | 110-119 | VB | denotes | postulate |
T684 | 106-109 | CC | denotes | and |
T683 | 104-105 | , | denotes | , |
T682 | 100-104 | NNP | denotes | WWOX |
T681 | 96-99 | CC | denotes | and |
T680 | 92-95 | NN | denotes | p53 |
T679 | 89-91 | IN | denotes | in |
T678 | 79-88 | NN | denotes | knowledge |
T677 | 71-78 | VBN | denotes | updated |
T676 | 67-70 | DT | denotes | the |
T675 | 63-66 | IN | denotes | for |
T674 | 54-62 | NN | denotes | overview |
T673 | 51-53 | DT | denotes | an |
T672 | 43-50 | VBP | denotes | provide |
T671 | 40-42 | PRP | denotes | we |
T670 | 38-39 | , | denotes | , |
T669 | 34-38 | RB | denotes | Here |
T668 | 32-33 | . | denotes | . |
T667 | 29-32 | NN | denotes | p53 |
T666 | 24-28 | NN | denotes | type |
T665 | 19-23 | JJ | denotes | wild |
T664 | 9-18 | VB | denotes | stabilize |
T663 | 5-8 | CC | denotes | and |
T662 | 0-4 | NN | denotes | bind |
T714 | 289-294 | IN | denotes | under |
R395 | T683 | T682 | punct | ",",WWOX |
R377 | T665 | T666 | amod | wild,type |
R378 | T666 | T667 | compound | type,p53 |
R379 | T667 | T664 | dobj | p53,stabilize |
R381 | T669 | T672 | advmod | Here,provide |
R382 | T670 | T672 | punct | ",",provide |
R383 | T671 | T672 | nsubj | we,provide |
R384 | T672 | T672 | ROOT | provide,provide |
R385 | T673 | T674 | det | an,overview |
R386 | T674 | T672 | dobj | overview,provide |
R387 | T675 | T674 | prep | for,overview |
R388 | T676 | T678 | det | the,knowledge |
R389 | T677 | T678 | amod | updated,knowledge |
R390 | T678 | T675 | pobj | knowledge,for |
R391 | T679 | T678 | prep | in,knowledge |
R392 | T680 | T679 | pobj | p53,in |
R393 | T681 | T680 | cc | and,p53 |
R394 | T682 | T680 | conj | WWOX,p53 |
R396 | T684 | T672 | cc | and,provide |
R397 | T685 | T672 | conj | postulate,provide |
R398 | T686 | T687 | amod | potential,scenarios |
R399 | T687 | T685 | dobj | scenarios,postulate |
R400 | T688 | T698 | nsubj | that,modulate |
R401 | T689 | T690 | amod | wild,type |
R402 | T690 | T698 | nsubj | type,modulate |
R403 | T691 | T690 | cc | and,type |
R404 | T692 | T693 | amod | mutant,p53 |
R405 | T693 | T690 | conj | p53,type |
R406 | T694 | T693 | punct | ",",p53 |
R407 | T695 | T693 | cc | or,p53 |
R408 | T696 | T693 | conj | isoforms,p53 |
R409 | T697 | T698 | punct | ",",modulate |
R410 | T698 | T687 | relcl | modulate,scenarios |
R411 | T699 | T701 | det | the,function |
R412 | T700 | T701 | amod | apoptotic,function |
R413 | T701 | T698 | dobj | function,modulate |
R414 | T702 | T701 | prep | of,function |
R415 | T703 | T702 | pobj | WWOX,of |
R416 | T704 | T672 | punct | .,provide |
R417 | T705 | T706 | nsubj | We,propose |
R418 | T706 | T706 | ROOT | propose,propose |
R419 | T707 | T719 | mark | that,needed |
R420 | T708 | T719 | csubj | triggering,needed |
R421 | T709 | T710 | compound | WWOX,activation |
R422 | T710 | T708 | dobj | activation,triggering |
R423 | T711 | T710 | prep | by,activation |
R424 | T712 | T713 | amod | therapeutic,drugs |
R425 | T713 | T711 | pobj | drugs,by |
R426 | T715 | T717 | amod | p53,deficiency |
R427 | T716 | T717 | amod | functional,deficiency |
R428 | T717 | T714 | pobj | deficiency,under |
R429 | T718 | T719 | auxpass | is,needed |
R430 | T719 | T706 | ccomp | needed,propose |
R431 | T720 | T721 | aux | to,overcome |
R432 | T721 | T719 | advcl | overcome,needed |
R433 | T722 | T723 | compound | TMZ,resistance |
R434 | T723 | T721 | dobj | resistance,overcome |
R435 | T724 | T721 | cc | and,overcome |
R436 | T725 | T721 | conj | induce,overcome |
R437 | T726 | T728 | compound | GBM,death |
R438 | T727 | T728 | compound | cell,death |
R439 | T728 | T725 | dobj | death,induce |
R440 | T729 | T706 | punct | .,propose |
R443 | T714 | T710 | prep | under,activation |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T548 | 252-267 | Positive_regulation | denotes | WWOX activation |
T545 | 252-256 | Protein | denotes | WWOX |
T544 | 343-346 | Entity | denotes | TMZ |
T542 | 271-288 | Entity | denotes | therapeutic drugs |
T538 | 92-95 | Protein | denotes | p53 |
T536 | 295-298 | Protein | denotes | p53 |
T530 | 216-223 | Protein | denotes | of WWOX |
T528 | 159-183 | Protein | denotes | mutant p53, or isoforms, |
T522 | 100-104 | Protein | denotes | WWOX |
T520 | 19-32 | Protein | denotes | wild type p53 |
R264 | T545 | T548 | themeOf | WWOX,WWOX activation |
DLUT931
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T424 | 241-251 | Positive_regulation | denotes | triggering |
T423 | 310-320 | Negative_regulation | denotes | deficiency |
T422 | 257-267 | Positive_regulation | denotes | activation |
T421 | 184-192 | Regulation | denotes | modulate |
T420 | 0-4 | Binding | denotes | bind |
T414 | 295-298 | Protein | denotes | p53 |
T413 | 252-256 | Protein | denotes | WWOX |
T412 | 219-223 | Protein | denotes | WWOX |
T411 | 166-169 | Protein | denotes | p53 |
T410 | 100-104 | Protein | denotes | WWOX |
T409 | 92-95 | Protein | denotes | p53 |
T408 | 29-32 | Protein | denotes | p53 |
R217 | T408 | T420 | themeOf | p53,bind |
R218 | T411 | T421 | causeOf | p53,modulate |
R219 | T412 | T421 | themeOf | WWOX,modulate |
R220 | T413 | T422 | themeOf | WWOX,activation |
R221 | T414 | T423 | themeOf | p53,deficiency |
R224 | T422 | T424 | themeOf | activation,triggering |
R225 | T423 | T424 | causeOf | deficiency,triggering |
BioNLP16_Messiy
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T473 | 257-267 | Positive_regulation | denotes | activation |
T472 | 241-251 | Positive_regulation | denotes | triggering |
T471 | 310-320 | Negative_regulation | denotes | deficiency |
T470 | 0-4 | Binding | denotes | bind |
T464 | 295-298 | Protein | denotes | p53 |
T463 | 252-256 | Protein | denotes | WWOX |
T462 | 219-223 | Protein | denotes | WWOX |
T461 | 166-169 | Protein | denotes | p53 |
T460 | 100-104 | Protein | denotes | WWOX |
T459 | 92-95 | Protein | denotes | p53 |
T458 | 29-32 | Protein | denotes | p53 |
R234 | T463 | T473 | themeOf | WWOX,activation |
R235 | T464 | T471 | themeOf | p53,deficiency |
R238 | T473 | T472 | themeOf | activation,triggering |
BioNLP16_DUT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T380 | 241-251 | Positive_regulation | denotes | triggering |
T379 | 257-267 | Positive_regulation | denotes | activation |
T378 | 310-320 | Negative_regulation | denotes | deficiency |
T377 | 0-4 | Binding | denotes | bind |
T376 | 9-18 | Positive_regulation | denotes | stabilize |
T372 | 295-298 | Protein | denotes | p53 |
T371 | 252-256 | Protein | denotes | WWOX |
T370 | 219-223 | Protein | denotes | WWOX |
T369 | 166-169 | Protein | denotes | p53 |
T368 | 100-104 | Protein | denotes | WWOX |
T367 | 92-95 | Protein | denotes | p53 |
T366 | 29-32 | Protein | denotes | p53 |
R207 | T366 | T376 | themeOf | p53,stabilize |
R208 | T371 | T379 | themeOf | WWOX,activation |
R209 | T372 | T378 | themeOf | p53,deficiency |
R211 | T379 | T380 | themeOf | activation,triggering |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T395 | 166-169 | http://www.uniprot.org/uniprot/P04637 | denotes | p53 |
T394 | 92-95 | http://www.uniprot.org/uniprot/P04637 | denotes | p53 |
T393 | 29-32 | http://www.uniprot.org/uniprot/P04637 | denotes | p53 |
T387 | 219-223 | http://www.uniprot.org/uniprot/Q9NZC7 | denotes | WWOX |
T386 | 100-104 | http://www.uniprot.org/uniprot/Q9NZC7 | denotes | WWOX |
bionlp-st-ge-2016-test-proteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T129 | 29-32 | Protein | denotes | p53 |
T130 | 92-95 | Protein | denotes | p53 |
T131 | 100-104 | Protein | denotes | WWOX |
T132 | 166-169 | Protein | denotes | p53 |
T133 | 219-223 | Protein | denotes | WWOX |
T134 | 252-256 | Protein | denotes | WWOX |
T135 | 295-298 | Protein | denotes | p53 |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T336 | 378-383 | NN | denotes | death |
T335 | 373-377 | NN | denotes | cell |
T334 | 369-372 | NN | denotes | GBM |
T333 | 362-368 | VB | denotes | induce |
T332 | 358-361 | CC | denotes | and |
T331 | 347-357 | NN | denotes | resistance |
T330 | 343-346 | NN | denotes | TMZ |
T329 | 334-342 | VB | denotes | overcome |
T328 | 331-333 | TO | denotes | to |
T327 | 324-330 | VB | denotes | needed |
T326 | 321-323 | VB | denotes | is |
T325 | 310-320 | NN | denotes | deficiency |
T324 | 299-309 | JJ | denotes | functional |
T323 | 295-298 | NN | denotes | p53 |
T322 | 289-294 | IN | denotes | under |
T321 | 283-288 | NN | denotes | drugs |
T320 | 271-282 | JJ | denotes | therapeutic |
T319 | 268-270 | IN | denotes | by |
T318 | 257-267 | NN | denotes | activation |
T317 | 252-256 | NN | denotes | WWOX |
T316 | 241-251 | VB | denotes | triggering |
T315 | 236-240 | IN | denotes | that |
T314 | 228-235 | VB | denotes | propose |
T313 | 225-227 | PRP | denotes | We |
T312 | 219-223 | NN | denotes | WWOX |
T311 | 216-218 | IN | denotes | of |
T310 | 207-215 | NN | denotes | function |
T309 | 197-206 | JJ | denotes | apoptotic |
T308 | 193-196 | DT | denotes | the |
T307 | 184-192 | VB | denotes | modulate |
T306 | 182-183 | -COMMA- | denotes | , |
T305 | 174-182 | NN | denotes | isoforms |
T304 | 171-173 | CC | denotes | or |
T303 | 169-170 | -COMMA- | denotes | , |
T302 | 166-169 | NN | denotes | p53 |
T301 | 159-165 | JJ | denotes | mutant |
T300 | 155-158 | CC | denotes | and |
T299 | 150-154 | NN | denotes | type |
T298 | 145-149 | JJ | denotes | wild |
T297 | 140-144 | IN | denotes | that |
T296 | 130-139 | NN | denotes | scenarios |
T295 | 120-129 | JJ | denotes | potential |
T294 | 110-119 | VB | denotes | postulate |
T293 | 106-109 | CC | denotes | and |
T292 | 104-105 | -COMMA- | denotes | , |
T291 | 100-104 | NN | denotes | WWOX |
T290 | 96-99 | CC | denotes | and |
T289 | 92-95 | NN | denotes | p53 |
T288 | 89-91 | IN | denotes | in |
T287 | 79-88 | NN | denotes | knowledge |
T286 | 71-78 | VB | denotes | updated |
T285 | 67-70 | DT | denotes | the |
T284 | 63-66 | IN | denotes | for |
T283 | 54-62 | NN | denotes | overview |
T282 | 51-53 | DT | denotes | an |
T281 | 43-50 | VB | denotes | provide |
T280 | 40-42 | PRP | denotes | we |
T279 | 38-39 | -COMMA- | denotes | , |
T278 | 34-38 | RB | denotes | Here |
T277 | 29-32 | NN | denotes | p53 |
T276 | 24-28 | NN | denotes | type |
T275 | 19-23 | JJ | denotes | wild |
T274 | 9-18 | VB | denotes | stabilize |
T273 | 5-8 | CC | denotes | and |
T272 | 0-4 | VB | denotes | bind |
R152 | T287 | T286 | arg2Of | knowledge,updated |
R135 | T272 | T273 | arg1Of | bind,and |
R139 | T274 | T273 | arg2Of | stabilize,and |
R140 | T277 | T272 | arg2Of | p53,bind |
R141 | T277 | T274 | arg2Of | p53,stabilize |
R142 | T277 | T275 | arg1Of | p53,wild |
R143 | T277 | T276 | arg1Of | p53,type |
R144 | T280 | T281 | arg1Of | we,provide |
R145 | T280 | T294 | arg1Of | we,postulate |
R146 | T281 | T293 | arg1Of | provide,and |
R147 | T283 | T281 | arg2Of | overview,provide |
R148 | T283 | T282 | arg1Of | overview,an |
R149 | T283 | T284 | arg1Of | overview,for |
R150 | T287 | T284 | arg2Of | knowledge,for |
R151 | T287 | T285 | arg1Of | knowledge,the |
R153 | T287 | T288 | arg1Of | knowledge,in |
R154 | T289 | T290 | arg1Of | p53,and |
R155 | T290 | T288 | arg2Of | and,in |
R156 | T291 | T290 | arg2Of | WWOX,and |
R157 | T293 | T278 | arg1Of | and,Here |
R158 | T293 | T279 | arg1Of | and,"," |
R159 | T293 | T292 | arg1Of | and,"," |
R160 | T294 | T293 | arg2Of | postulate,and |
R161 | T296 | T294 | arg2Of | scenarios,postulate |
R162 | T296 | T295 | arg1Of | scenarios,potential |
R163 | T296 | T297 | arg1Of | scenarios,that |
R164 | T299 | T298 | arg1Of | type,wild |
R165 | T299 | T300 | arg1Of | type,and |
R166 | T300 | T304 | arg1Of | and,or |
R167 | T302 | T300 | arg2Of | p53,and |
R168 | T302 | T301 | arg1Of | p53,mutant |
R169 | T304 | T303 | arg1Of | or,"," |
R170 | T304 | T307 | arg1Of | or,modulate |
R171 | T305 | T304 | arg2Of | isoforms,or |
R172 | T307 | T297 | arg2Of | modulate,that |
R173 | T307 | T306 | arg1Of | modulate,"," |
R174 | T310 | T307 | arg2Of | function,modulate |
R175 | T310 | T308 | arg1Of | function,the |
R176 | T310 | T309 | arg1Of | function,apoptotic |
R177 | T310 | T311 | arg1Of | function,of |
R178 | T312 | T311 | arg2Of | WWOX,of |
R179 | T313 | T314 | arg1Of | We,propose |
R180 | T318 | T316 | arg1Of | activation,triggering |
R181 | T318 | T317 | arg1Of | activation,WWOX |
R182 | T318 | T319 | arg1Of | activation,by |
R183 | T318 | T322 | arg1Of | activation,under |
R184 | T318 | T326 | arg1Of | activation,is |
R185 | T318 | T327 | arg2Of | activation,needed |
R186 | T321 | T319 | arg2Of | drugs,by |
R187 | T321 | T320 | arg1Of | drugs,therapeutic |
R188 | T325 | T322 | arg2Of | deficiency,under |
R189 | T325 | T323 | arg1Of | deficiency,p53 |
R190 | T325 | T324 | arg1Of | deficiency,functional |
R191 | T327 | T314 | arg2Of | needed,propose |
R192 | T327 | T315 | arg1Of | needed,that |
R193 | T327 | T326 | arg2Of | needed,is |
R194 | T327 | T328 | modOf | needed,to |
R195 | T329 | T332 | arg1Of | overcome,and |
R196 | T331 | T329 | arg2Of | resistance,overcome |
R197 | T331 | T330 | arg1Of | resistance,TMZ |
R198 | T332 | T328 | arg1Of | and,to |
R199 | T333 | T332 | arg2Of | induce,and |
R200 | T336 | T333 | arg2Of | death,induce |
R201 | T336 | T334 | arg1Of | death,GBM |
R202 | T336 | T335 | arg1Of | death,cell |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T144 | 378-383 | http://purl.obolibrary.org/obo/GO_0016265 | denotes | death |
T143 | 373-383 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | cell death |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T147 | 373-377 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T86 | 225-384 | Sentence | denotes | We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death. |
T85 | 34-224 | Sentence | denotes | Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild type and mutant p53, or isoforms, modulate the apoptotic function of WWOX. |
T8 | 34-224 | Sentence | denotes | Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild type and mutant p53, or isoforms, modulate the apoptotic function of WWOX. |
T9 | 225-384 | Sentence | denotes | We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death. |
simple1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T165 | 295-298 | Protein | denotes | p53 |
T164 | 252-256 | Protein | denotes | WWOX |
T163 | 219-223 | Protein | denotes | WWOX |
T162 | 166-169 | Protein | denotes | p53 |
T161 | 100-104 | Protein | denotes | WWOX |
T160 | 92-95 | Protein | denotes | p53 |
T159 | 29-32 | Protein | denotes | p53 |