PMC:3585731 / 16234-16461 JSONTXT

{"project":"testone","denotations":[{"id":"T5151","span":{"begin":90,"end":105},"obj":"Phosphorylation"},{"id":"T5150","span":{"begin":65,"end":74},"obj":"Positive_regulation"},{"id":"T5089","span":{"begin":215,"end":219},"obj":"Protein"}],"relations":[{"id":"R3537","pred":"themeOf","subj":"T5151","obj":"T5150"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"pmc-enju-pas","denotations":[{"id":"T6320","span":{"begin":57,"end":64},"obj":"VB"},{"id":"T6319","span":{"begin":48,"end":56},"obj":"VB"},{"id":"T6318","span":{"begin":44,"end":47},"obj":"DT"},{"id":"T6317","span":{"begin":39,"end":43},"obj":"IN"},{"id":"T6316","span":{"begin":30,"end":38},"obj":"VB"},{"id":"T6315","span":{"begin":22,"end":29},"obj":"NN"},{"id":"T6314","span":{"begin":16,"end":21},"obj":"DT"},{"id":"T6313","span":{"begin":14,"end":15},"obj":"-COMMA-"},{"id":"T6312","span":{"begin":6,"end":14},"obj":"RB"},{"id":"T6311","span":{"begin":0,"end":5},"obj":"VB"},{"id":"T6344","span":{"begin":220,"end":226},"obj":"NN"},{"id":"T6343","span":{"begin":215,"end":219},"obj":"NN"},{"id":"T6342","span":{"begin":210,"end":214},"obj":"IN"},{"id":"T6341","span":{"begin":199,"end":209},"obj":"RB"},{"id":"T6340","span":{"begin":189,"end":198},"obj":"NN"},{"id":"T6339","span":{"begin":177,"end":188},"obj":"JJ"},{"id":"T6338","span":{"begin":174,"end":176},"obj":"IN"},{"id":"T6337","span":{"begin":161,"end":173},"obj":"NN"},{"id":"T6336","span":{"begin":152,"end":160},"obj":"JJ"},{"id":"T6335","span":{"begin":142,"end":151},"obj":"VB"},{"id":"T6334","span":{"begin":140,"end":141},"obj":"-COMMA-"},{"id":"T6333","span":{"begin":135,"end":140},"obj":"NN"},{"id":"T6332","span":{"begin":130,"end":134},"obj":"NN"},{"id":"T6331","span":{"begin":127,"end":129},"obj":"IN"},{"id":"T6330","span":{"begin":121,"end":126},"obj":"NN"},{"id":"T6329","span":{"begin":117,"end":120},"obj":"DT"},{"id":"T6328","span":{"begin":107,"end":116},"obj":"VB"},{"id":"T6327","span":{"begin":105,"end":106},"obj":"-COMMA-"},{"id":"T6326","span":{"begin":90,"end":105},"obj":"NN"},{"id":"T6325","span":{"begin":86,"end":89},"obj":"NN"},{"id":"T6324","span":{"begin":82,"end":85},"obj":"CC"},{"id":"T6323","span":{"begin":78,"end":81},"obj":"NN"},{"id":"T6322","span":{"begin":75,"end":77},"obj":"IN"},{"id":"T6321","span":{"begin":65,"end":74},"obj":"NN"}],"relations":[{"id":"R4363","pred":"arg1Of","subj":"T6311","obj":"T6312"},{"id":"R4364","pred":"arg1Of","subj":"T6315","obj":"T6314"},{"id":"R4365","pred":"arg1Of","subj":"T6315","obj":"T6316"},{"id":"R4366","pred":"modOf","subj":"T6316","obj":"T6311"},{"id":"R4367","pred":"arg1Of","subj":"T6316","obj":"T6313"},{"id":"R4368","pred":"arg1Of","subj":"T6321","obj":"T6318"},{"id":"R4369","pred":"arg2Of","subj":"T6321","obj":"T6319"},{"id":"R4370","pred":"arg2Of","subj":"T6321","obj":"T6320"},{"id":"R4371","pred":"arg1Of","subj":"T6321","obj":"T6322"},{"id":"R4372","pred":"arg1Of","subj":"T6321","obj":"T6327"},{"id":"R4373","pred":"arg1Of","subj":"T6321","obj":"T6335"},{"id":"R4374","pred":"arg1Of","subj":"T6323","obj":"T6324"},{"id":"R4375","pred":"arg2Of","subj":"T6325","obj":"T6324"},{"id":"R4376","pred":"arg2Of","subj":"T6326","obj":"T6322"},{"id":"R4377","pred":"arg1Of","subj":"T6326","obj":"T6323"},{"id":"R4378","pred":"arg1Of","subj":"T6326","obj":"T6325"},{"id":"R4379","pred":"arg2Of","subj":"T6328","obj":"T6327"},{"id":"R4380","pred":"arg2Of","subj":"T6330","obj":"T6328"},{"id":"R4381","pred":"arg1Of","subj":"T6330","obj":"T6329"},{"id":"R4382","pred":"arg1Of","subj":"T6330","obj":"T6331"},{"id":"R4383","pred":"arg2Of","subj":"T6333","obj":"T6331"},{"id":"R4384","pred":"arg1Of","subj":"T6333","obj":"T6332"},{"id":"R4385","pred":"arg2Of","subj":"T6335","obj":"T6316"},{"id":"R4386","pred":"arg1Of","subj":"T6335","obj":"T6317"},{"id":"R4387","pred":"arg1Of","subj":"T6335","obj":"T6334"},{"id":"R4388","pred":"arg1Of","subj":"T6335","obj":"T6342"},{"id":"R4389","pred":"arg2Of","subj":"T6337","obj":"T6335"},{"id":"R4390","pred":"arg1Of","subj":"T6337","obj":"T6336"},{"id":"R4391","pred":"arg1Of","subj":"T6337","obj":"T6338"},{"id":"R4392","pred":"arg1Of","subj":"T6337","obj":"T6341"},{"id":"R4393","pred":"arg2Of","subj":"T6340","obj":"T6338"},{"id":"R4394","pred":"arg1Of","subj":"T6340","obj":"T6339"},{"id":"R4395","pred":"arg2Of","subj":"T6344","obj":"T6342"},{"id":"R4396","pred":"arg1Of","subj":"T6344","obj":"T6343"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T5400","span":{"begin":215,"end":219},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T6491","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T6435","span":{"begin":215,"end":219},"obj":"http://www.uniprot.org/uniprot/Q13546"},{"id":"T6519","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T6463","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/P31749"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"GO-BP","denotations":[{"id":"T5489","span":{"begin":189,"end":198},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T5481","span":{"begin":90,"end":105},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5460","span":{"begin":86,"end":89},"obj":"http://purl.obolibrary.org/obo/GO_0004705"},{"id":"T5445","span":{"begin":130,"end":140},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T5436","span":{"begin":135,"end":140},"obj":"http://purl.obolibrary.org/obo/GO_0016265"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"GO-MF","denotations":[{"id":"T5508","span":{"begin":86,"end":89},"obj":"http://purl.obolibrary.org/obo/GO_0004705"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"GO-CC","denotations":[{"id":"T5518","span":{"begin":130,"end":134},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"sentences","denotations":[{"id":"T5309","span":{"begin":0,"end":227},"obj":"Sentence"},{"id":"T101","span":{"begin":0,"end":227},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"simple1","denotations":[{"id":"T5553","span":{"begin":215,"end":219},"obj":"Protein"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T6412","span":{"begin":215,"end":219},"obj":"Protein"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T6693","span":{"begin":215,"end":219},"obj":"Protein"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"DLUT931","denotations":[{"id":"T6573","span":{"begin":215,"end":219},"obj":"Protein"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T7309","span":{"begin":86,"end":106},"obj":"Phosphorylation"},{"id":"T7243","span":{"begin":86,"end":89},"obj":"Protein"},{"id":"T7168","span":{"begin":215,"end":226},"obj":"Protein"},{"id":"T7167","span":{"begin":215,"end":219},"obj":"Protein"},{"id":"T7163","span":{"begin":127,"end":134},"obj":"Entity"},{"id":"T7149","span":{"begin":78,"end":81},"obj":"Protein"}],"relations":[{"id":"R4755","pred":"themeOf","subj":"T7243","obj":"T7309"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T6927","span":{"begin":65,"end":74},"obj":"Positive_regulation"},{"id":"T6926","span":{"begin":65,"end":74},"obj":"Positive_regulation"},{"id":"T6925","span":{"begin":90,"end":105},"obj":"Phosphorylation"},{"id":"T6924","span":{"begin":90,"end":105},"obj":"Phosphorylation"},{"id":"T6923","span":{"begin":65,"end":74},"obj":"Positive_regulation"},{"id":"T6922","span":{"begin":215,"end":226},"obj":"Protein"},{"id":"T6921","span":{"begin":86,"end":89},"obj":"Protein"},{"id":"T6920","span":{"begin":78,"end":81},"obj":"Protein"}],"relations":[{"id":"R4603","pred":"themeOf","subj":"T6920","obj":"T6923"},{"id":"R4605","pred":"themeOf","subj":"T6920","obj":"T6924"},{"id":"R4608","pred":"themeOf","subj":"T6921","obj":"T6925"},{"id":"R4614","pred":"themeOf","subj":"T6924","obj":"T6926"},{"id":"R4616","pred":"themeOf","subj":"T6925","obj":"T6927"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}

{"project":"test3","denotations":[{"id":"T5276","span":{"begin":215,"end":219},"obj":"Protein"},{"id":"T5275","span":{"begin":65,"end":74},"obj":"Positive_regulation"},{"id":"T5185","span":{"begin":215,"end":219},"obj":"Protein"}],"text":"Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase."}