PMC:3585731 / 0-600 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3585731","sourcedb":"PMC","sourceid":"3585731","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3585731","text":"Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis\nInterplay of Akt and JNK in Necroptosis Control\n\nAbstract\nNecroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. 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