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PMC:3585731 / 0-600 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T11 14-18 Protein denotes TNFα
T12 43-47 Protein denotes RIP1
T21 4-13 Regulation denotes Regulates
T22 580-584 Regulation denotes role
T15 588-592 Protein denotes TNFα
T14 475-479 Protein denotes RIP1
T13 443-473 Protein denotes receptor interacting protein-1
R1 T14 T13 equivalentTo RIP1,receptor interacting protein-1

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T153 0-3 NN denotes Akt
T154 4-13 VB denotes Regulates
T155 14-18 NNP denotes TNFα
T156 19-28 NNP denotes Synthesis
T157 29-39 NNP denotes Downstream
T158 40-42 IN denotes of
T159 43-47 NN denotes RIP1
T160 48-54 NN denotes Kinase
T161 55-65 NN denotes Activation
T162 66-72 IN denotes during
T163 73-84 NN denotes Necroptosis
T234 588-592 NN denotes TNFα
T233 585-587 IN denotes in
T232 580-584 NN denotes role
T231 576-579 JJ denotes key
T230 574-575 DT denotes a
T229 568-573 VB denotes plays
T228 564-567 CC denotes and
T227 558-563 NN denotes cells
T226 553-557 NN denotes L929
T225 550-552 IN denotes in
T224 538-549 NN denotes necroptosis
T223 534-537 IN denotes for
T222 525-533 JJ denotes critical
T221 522-524 VB denotes is
T220 513-521 NN denotes activity
T219 506-512 NN denotes kinase
T218 502-505 NN denotes Akt
T217 497-501 IN denotes that
T216 492-496 VB denotes show
T215 489-491 PRP denotes We
T214 481-487 NN denotes kinase
T213 479-480 -RRB- denotes )
T212 475-479 NN denotes RIP1
T211 474-475 -LRB- denotes (
T210 464-473 NN denotes protein-1
T209 452-463 NN denotes interacting
T208 443-451 NN denotes receptor
T207 434-442 NN denotes mediator
T206 422-433 NN denotes necroptosis
T205 418-421 DT denotes the
T204 415-417 IN denotes by
T203 404-414 VB denotes controlled
T202 393-403 NN denotes mechanisms
T201 383-392 NN denotes signaling
T200 379-382 DT denotes the
T199 366-378 VB denotes investigated
T198 363-365 PRP denotes we
T197 361-362 -COMMA- denotes ,
T196 357-361 NN denotes work
T195 352-356 DT denotes this
T194 349-351 IN denotes In
T193 346-347 -RRB- denotes )
T192 342-346 NN denotes SIRS
T191 341-342 -LRB- denotes (
T190 332-340 NN denotes syndrome
T189 323-331 NN denotes response
T188 310-322 JJ denotes inflammatory
T187 301-309 JJ denotes systemic
T186 297-300 CC denotes and
T185 284-296 NN denotes inflammation
T184 273-283 JJ denotes intestinal
T183 263-272 VB denotes including
T182 254-262 NN denotes diseases
T181 246-253 JJ denotes various
T180 243-245 IN denotes of
T179 230-242 NN denotes pathogenesis
T178 226-229 DT denotes the
T177 223-225 IN denotes in
T176 212-222 VB denotes implicated
T175 207-211 VB denotes been
T174 203-206 VB denotes has
T173 198-202 WDT denotes that
T172 192-197 NN denotes death
T171 187-191 NN denotes cell
T170 178-186 JJ denotes necrotic
T169 175-177 IN denotes of
T168 170-174 NN denotes form
T167 160-169 VB denotes regulated
T166 158-159 DT denotes a
T165 155-157 VB denotes is
T164 143-154 NN denotes Necroptosis
R15 T153 T154 arg1Of Akt,Regulates
R16 T154 T162 arg1Of Regulates,during
R17 T157 T154 arg2Of Downstream,Regulates
R18 T157 T155 arg1Of Downstream,TNFα
R19 T157 T156 arg1Of Downstream,Synthesis
R20 T157 T158 arg1Of Downstream,of
R21 T161 T158 arg2Of Activation,of
R22 T161 T159 arg1Of Activation,RIP1
R23 T161 T160 arg1Of Activation,Kinase
R24 T163 T162 arg2Of Necroptosis,during
R25 T164 T165 arg1Of Necroptosis,is
R26 T168 T165 arg2Of form,is
R27 T168 T166 arg1Of form,a
R28 T168 T167 arg2Of form,regulated
R29 T168 T169 arg1Of form,of
R30 T168 T173 arg1Of form,that
R31 T168 T174 arg1Of form,has
R32 T168 T175 arg1Of form,been
R33 T168 T176 arg2Of form,implicated
R34 T172 T169 arg2Of death,of
R35 T172 T170 arg1Of death,necrotic
R36 T172 T171 arg1Of death,cell
R37 T176 T174 arg2Of implicated,has
R38 T176 T175 arg2Of implicated,been
R39 T176 T177 arg1Of implicated,in
R40 T179 T177 arg2Of pathogenesis,in
R41 T179 T178 arg1Of pathogenesis,the
R42 T179 T180 arg1Of pathogenesis,of
R43 T182 T180 arg2Of diseases,of
R44 T182 T181 arg1Of diseases,various
R45 T182 T183 arg1Of diseases,including
R46 T185 T184 arg1Of inflammation,intestinal
R47 T185 T186 arg1Of inflammation,and
R48 T186 T183 arg2Of and,including
R49 T190 T186 arg2Of syndrome,and
R50 T190 T187 arg1Of syndrome,systemic
R51 T190 T188 arg1Of syndrome,inflammatory
R52 T190 T189 arg1Of syndrome,response
R53 T190 T191 arg1Of syndrome,(
R54 T192 T191 arg2Of SIRS,(
R55 T193 T191 arg3Of ),(
R56 T196 T194 arg2Of work,In
R57 T196 T195 arg1Of work,this
R58 T198 T199 arg1Of we,investigated
R59 T199 T194 arg1Of investigated,In
R60 T199 T197 arg1Of investigated,","
R61 T202 T199 arg2Of mechanisms,investigated
R62 T202 T200 arg1Of mechanisms,the
R63 T202 T201 arg1Of mechanisms,signaling
R64 T202 T203 arg2Of mechanisms,controlled
R65 T212 T211 arg2Of RIP1,(
R66 T213 T211 arg3Of ),(
R67 T214 T203 arg1Of kinase,controlled
R68 T214 T204 arg2Of kinase,by
R69 T214 T205 arg1Of kinase,the
R70 T214 T206 arg1Of kinase,necroptosis
R71 T214 T207 arg1Of kinase,mediator
R72 T214 T208 arg1Of kinase,receptor
R73 T214 T209 arg1Of kinase,interacting
R74 T214 T210 arg1Of kinase,protein-1
R75 T214 T211 arg1Of kinase,(
R76 T215 T216 arg1Of We,show
R77 T220 T218 arg1Of activity,Akt
R78 T220 T219 arg1Of activity,kinase
R79 T220 T221 arg1Of activity,is
R80 T220 T222 arg1Of activity,critical
R81 T220 T229 arg1Of activity,plays
R82 T221 T225 arg1Of is,in
R83 T221 T228 arg1Of is,and
R84 T222 T221 arg2Of critical,is
R85 T222 T223 arg1Of critical,for
R86 T224 T223 arg2Of necroptosis,for
R87 T227 T225 arg2Of cells,in
R88 T227 T226 arg1Of cells,L929
R89 T228 T216 arg2Of and,show
R90 T228 T217 arg1Of and,that
R91 T229 T228 arg2Of plays,and
R92 T229 T233 arg1Of plays,in
R93 T232 T229 arg2Of role,plays
R94 T232 T230 arg1Of role,a
R95 T232 T231 arg1Of role,key

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T88 14-18 Protein denotes TNFα
T89 43-47 Protein denotes RIP1
T90 443-473 Protein denotes receptor interacting protein-1
T91 475-479 Protein denotes RIP1
T92 588-592 Protein denotes TNFα

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T387 0-3 http://www.uniprot.org/uniprot/P31751 denotes Akt
T394 0-3 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T401 14-18 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T405 43-47 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T406 475-479 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T402 588-592 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T395 502-505 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T388 502-505 http://www.uniprot.org/uniprot/P31751 denotes Akt
T380 0-3 http://www.uniprot.org/uniprot/P31749 denotes Akt
T381 502-505 http://www.uniprot.org/uniprot/P31749 denotes Akt

UBERON-AE

Id Subject Object Predicate Lexical cue
T58 273-283 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal

GO-BP

Id Subject Object Predicate Lexical cue
T98 19-28 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T99 73-84 http://purl.obolibrary.org/obo/GO_0070266 denotes Necroptosis
T107 73-84 http://purl.obolibrary.org/obo/GO_0097528 denotes Necroptosis
T129 506-521 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T127 383-392 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T126 310-331 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T125 284-296 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T124 230-242 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T121 192-197 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T118 187-197 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T117 178-197 http://purl.obolibrary.org/obo/GO_0097300 denotes necrotic cell death
T116 178-197 http://purl.obolibrary.org/obo/GO_0070265 denotes necrotic cell death
T115 178-197 http://purl.obolibrary.org/obo/GO_0010939 denotes necrotic cell death
T110 538-549 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T109 422-433 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T108 143-154 http://purl.obolibrary.org/obo/GO_0097528 denotes Necroptosis
T102 538-549 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T101 422-433 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T100 143-154 http://purl.obolibrary.org/obo/GO_0070266 denotes Necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T135 506-521 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity

GO-CC

Id Subject Object Predicate Lexical cue
T137 187-191 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

sentences

Id Subject Object Predicate Lexical cue
T60 0-84 Sentence denotes Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
T61 143-348 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T62 349-488 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T1 0-84 Sentence denotes Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
T2 85-132 Sentence denotes Interplay of Akt and JNK in Necroptosis Control
T3 134-142 Sentence denotes Abstract
T4 143-348 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T5 349-488 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.

simple1

Id Subject Object Predicate Lexical cue
T145 443-473 Protein denotes receptor interacting protein-1
T146 475-479 Protein denotes RIP1
T147 588-592 Protein denotes TNFα
T143 14-18 Protein denotes TNFα
T144 43-47 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T353 14-18 Protein denotes TNFα
T354 43-47 Protein denotes RIP1
T363 4-13 Regulation denotes Regulates
T364 19-28 Gene_expression denotes Synthesis
T355 443-473 Protein denotes receptor interacting protein-1
T356 475-479 Protein denotes RIP1
T357 588-592 Protein denotes TNFα
T365 55-65 Positive_regulation denotes Activation
T366 580-584 Regulation denotes role
R450 T353 T364 themeOf TNFα,Synthesis
R451 T354 T365 themeOf RIP1,Activation
R455 T364 T363 themeOf Synthesis,Regulates

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T441 14-18 Protein denotes TNFα
T442 43-47 Protein denotes RIP1
T451 19-28 Gene_expression denotes Synthesis
T452 4-13 Regulation denotes Regulates
T453 55-65 Positive_regulation denotes Activation
T443 443-473 Protein denotes receptor interacting protein-1
T444 475-479 Protein denotes RIP1
T445 588-592 Protein denotes TNFα
R469 T441 T451 themeOf TNFα,Synthesis
R470 T442 T453 themeOf RIP1,Activation
R473 T451 T452 themeOf Synthesis,Regulates

DLUT931

Id Subject Object Predicate Lexical cue
T424 580-584 Regulation denotes role
T410 14-18 Protein denotes TNFα
T411 43-47 Protein denotes RIP1
T420 19-28 Gene_expression denotes Synthesis
T421 55-65 Positive_regulation denotes Activation
T422 4-13 Regulation denotes Regulates
T412 443-473 Protein denotes receptor interacting protein-1
T413 475-479 Protein denotes RIP1
T414 588-592 Protein denotes TNFα
R457 T410 T420 themeOf TNFα,Synthesis
R458 T411 T421 themeOf RIP1,Activation
R462 T420 T422 themeOf Synthesis,Regulates

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T728 0-3 Protein denotes Akt
T741 43-54 Protein denotes RIP1 Kinase
T744 14-17 Protein denotes TNF
T753 43-47 Protein denotes RIP1
T765 43-84 Positive_regulation denotes RIP1 Kinase Activation during Necroptosis
T748 415-487 Protein denotes by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase
T746 475-479 Protein denotes RIP1
T743 502-505 Protein denotes Akt
T742 502-512 Protein denotes Akt kinase
T736 443-480 Protein denotes receptor interacting protein-1 (RIP1)
T734 588-592 Protein denotes TNFα
R435 T741 T765 themeOf RIP1 Kinase,RIP1 Kinase Activation during Necroptosis

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T487 0-3 NNP denotes Akt
T488 4-13 VBZ denotes Regulates
T489 14-18 NNP denotes TNFα
T490 19-28 NNP denotes Synthesis
T491 29-39 NNP denotes Downstream
T492 40-42 IN denotes of
T493 43-47 NNP denotes RIP1
T494 48-54 NNP denotes Kinase
T495 55-65 NNP denotes Activation
T496 66-72 IN denotes during
T497 73-84 NNP denotes Necroptosis
T533 363-365 PRP denotes we
T532 361-362 , denotes ,
T531 357-361 NN denotes work
T530 352-356 DT denotes this
T529 349-351 IN denotes In
T528 347-348 . denotes .
T527 346-347 -RRB- denotes )
T526 342-346 NNP denotes SIRS
T525 341-342 -LRB- denotes (
T524 332-340 NN denotes syndrome
T523 323-331 NN denotes response
T522 310-322 JJ denotes inflammatory
T521 301-309 JJ denotes systemic
T520 297-300 CC denotes and
T519 284-296 NN denotes inflammation
T518 273-283 JJ denotes intestinal
T517 263-272 VBG denotes including
T516 254-262 NNS denotes diseases
T515 246-253 JJ denotes various
T514 243-245 IN denotes of
T513 230-242 NN denotes pathogenesis
T512 226-229 DT denotes the
T511 223-225 IN denotes in
T510 212-222 VBN denotes implicated
T509 207-211 VBN denotes been
T508 203-206 VBZ denotes has
T507 198-202 WDT denotes that
T506 192-197 NN denotes death
T505 187-191 NN denotes cell
T504 178-186 JJ denotes necrotic
T503 175-177 IN denotes of
T502 170-174 NN denotes form
T501 160-169 JJ denotes regulated
T500 158-159 DT denotes a
T499 155-157 VBZ denotes is
T498 143-154 NNP denotes Necroptosis
T570 588-592 JJ denotes TNFα
T569 585-587 IN denotes in
T568 580-584 NN denotes role
T567 576-579 JJ denotes key
T566 574-575 DT denotes a
T565 568-573 VBZ denotes plays
T564 564-567 CC denotes and
T563 558-563 NNS denotes cells
T562 553-557 CD denotes L929
T561 550-552 IN denotes in
T560 538-549 NN denotes necroptosis
T559 534-537 IN denotes for
T558 525-533 JJ denotes critical
T557 522-524 VBZ denotes is
T556 513-521 NN denotes activity
T555 506-512 NN denotes kinase
T554 502-505 NNP denotes Akt
T553 497-501 IN denotes that
T552 492-496 VBP denotes show
T551 489-491 PRP denotes We
T550 487-488 . denotes .
T549 481-487 NN denotes kinase
T548 479-480 -RRB- denotes )
T547 475-479 CD denotes RIP1
T546 474-475 -LRB- denotes (
T545 464-473 NN denotes protein-1
T544 452-463 VBG denotes interacting
T543 443-451 NN denotes receptor
T542 434-442 NN denotes mediator
T541 422-433 NN denotes necroptosis
T540 418-421 DT denotes the
T539 415-417 IN denotes by
T538 404-414 VBN denotes controlled
T537 393-403 NNS denotes mechanisms
T536 383-392 VBG denotes signaling
T535 379-382 DT denotes the
T534 366-378 VBD denotes investigated
R228 T488 T488 ROOT Regulates,Regulates
R229 T489 T491 compound TNFα,Downstream
R230 T490 T491 compound Synthesis,Downstream
R231 T491 T488 dobj Downstream,Regulates
R232 T492 T491 prep of,Downstream
R233 T493 T494 compound RIP1,Kinase
R234 T494 T495 compound Kinase,Activation
R235 T495 T492 pobj Activation,of
R236 T496 T488 prep during,Regulates
R237 T497 T498 compound Necroptosis,Necroptosis
R238 T498 T496 pobj Necroptosis,during
R239 T499 T488 conj is,Regulates
R240 T500 T502 det a,form
R241 T501 T502 amod regulated,form
R242 T502 T499 attr form,is
R243 T503 T502 prep of,form
R244 T504 T506 amod necrotic,death
R245 T505 T506 compound cell,death
R246 T506 T503 pobj death,of
R247 T507 T510 nsubjpass that,implicated
R248 T508 T510 aux has,implicated
R249 T509 T510 auxpass been,implicated
R250 T510 T506 relcl implicated,death
R251 T511 T510 prep in,implicated
R252 T512 T513 det the,pathogenesis
R253 T513 T511 pobj pathogenesis,in
R254 T514 T513 prep of,pathogenesis
R255 T515 T516 amod various,diseases
R256 T516 T514 pobj diseases,of
R257 T517 T516 prep including,diseases
R258 T518 T519 amod intestinal,inflammation
R259 T519 T517 pobj inflammation,including
R260 T520 T519 cc and,inflammation
R261 T521 T524 amod systemic,syndrome
R262 T522 T523 amod inflammatory,response
R263 T523 T524 compound response,syndrome
R264 T524 T519 conj syndrome,inflammation
R265 T525 T524 punct (,syndrome
R266 T526 T524 appos SIRS,syndrome
R267 T527 T524 punct ),syndrome
R268 T528 T488 punct .,Regulates
R269 T529 T534 prep In,investigated
R270 T530 T531 det this,work
R271 T531 T529 pobj work,In
R272 T532 T534 punct ",",investigated
R273 T533 T534 nsubj we,investigated
R274 T534 T534 ROOT investigated,investigated
R275 T535 T537 det the,mechanisms
R276 T536 T537 amod signaling,mechanisms
R277 T537 T534 dobj mechanisms,investigated
R278 T538 T537 acl controlled,mechanisms
R279 T539 T538 agent by,controlled
R280 T540 T543 det the,receptor
R281 T541 T542 amod necroptosis,mediator
R282 T542 T543 compound mediator,receptor
R283 T543 T539 pobj receptor,by
R284 T544 T543 acl interacting,receptor
R285 T545 T544 dobj protein-1,interacting
R286 T546 T545 punct (,protein-1
R287 T547 T545 appos RIP1,protein-1
R288 T548 T545 punct ),protein-1
R289 T549 T543 conj kinase,receptor
R290 T550 T534 punct .,investigated
R291 T551 T552 nsubj We,show
R292 T552 T552 ROOT show,show
R293 T553 T557 mark that,is
R294 T554 T556 compound Akt,activity
R295 T555 T556 compound kinase,activity
R296 T556 T557 nsubj activity,is
R297 T557 T552 ccomp is,show
R298 T558 T557 acomp critical,is
R299 T559 T558 prep for,critical
R300 T560 T559 pobj necroptosis,for
R301 T561 T557 prep in,is
R302 T562 T563 nummod L929,cells
R303 T563 T561 pobj cells,in
R304 T564 T557 cc and,is
R305 T565 T557 conj plays,is
R306 T566 T568 det a,role
R307 T567 T568 amod key,role
R308 T568 T565 dobj role,plays
R309 T569 T568 prep in,role
R227 T487 T488 nsubj Akt,Regulates

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T456 0-3 Protein denotes Akt
T457 14-18 Protein denotes TNFα
T458 43-54 Protein denotes RIP1 Kinase
T459 19-28 Gene_expression denotes Synthesis
T460 55-65 Positive_regulation denotes Activation
T461 4-13 Regulation denotes Regulates
T467 588-592 Protein denotes TNFα
T466 502-512 Protein denotes Akt kinase
T465 404-414 Regulation denotes controlled
T464 404-414 Regulation denotes controlled
T463 475-479 Protein denotes RIP1
T462 434-473 Protein denotes mediator receptor interacting protein-1
R212 T456 T461 causeOf Akt,Regulates
R213 T457 T459 themeOf TNFα,Synthesis
R214 T458 T460 themeOf RIP1 Kinase,Activation
R215 T459 T461 themeOf Synthesis,Regulates
R216 T462 T464 themeOf mediator receptor interacting protein-1,controlled
R217 T463 T465 themeOf RIP1,controlled

test3

Id Subject Object Predicate Lexical cue
T29 14-18 Protein denotes TNFα
T30 43-47 Protein denotes RIP1
T39 4-13 Regulation denotes Regulates
T40 14-18 Protein denotes TNFα
T41 19-28 Gene_expression denotes Synthesis
T42 43-47 Protein denotes RIP1
T47 588-592 Protein denotes TNFα
T46 580-584 Regulation denotes role
T45 475-479 Protein denotes RIP1
T44 443-473 Protein denotes receptor interacting protein-1
T43 404-414 Regulation denotes controlled
T33 588-592 Protein denotes TNFα
T32 475-479 Protein denotes RIP1
T31 443-473 Protein denotes receptor interacting protein-1
R6 T40 T41 themeOf TNFα,Synthesis
R7 T41 T39 themeOf Synthesis,Regulates
R8 T44 T43 causeOf receptor interacting protein-1,controlled
R9 T45 T44 equivalentTo RIP1,receptor interacting protein-1