PMC:3359311 / 0-383 JSONTXT

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T363","span":{"begin":22,"end":27},"obj":"P01584"},{"id":"T364","span":{"begin":288,"end":306},"obj":"P01584"},{"id":"T365","span":{"begin":308,"end":313},"obj":"P01584"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T37","span":{"begin":13,"end":21},"obj":"Positive_regulation"},{"id":"T38","span":{"begin":22,"end":27},"obj":"Protein"},{"id":"T39","span":{"begin":28,"end":38},"obj":"Gene_expression"},{"id":"T40","span":{"begin":288,"end":306},"obj":"Protein"},{"id":"T41","span":{"begin":308,"end":313},"obj":"Protein"},{"id":"T42","span":{"begin":347,"end":356},"obj":"Localization"}],"relations":[{"id":"R23","pred":"themeOf","subj":"T38","obj":"T39"},{"id":"R24","pred":"themeOf","subj":"T39","obj":"T37"},{"id":"R25","pred":"equivalentTo","subj":"T41","obj":"T40"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T802","span":{"begin":288,"end":306},"obj":"Protein"},{"id":"T803","span":{"begin":308,"end":313},"obj":"Protein"},{"id":"T804","span":{"begin":337,"end":345},"obj":"Positive_regulation"},{"id":"T805","span":{"begin":337,"end":345},"obj":"Positive_regulation"},{"id":"T807","span":{"begin":347,"end":356},"obj":"Localization"}],"relations":[{"id":"R667","pred":"themeOf","subj":"T802","obj":"T804"},{"id":"R668","pred":"themeOf","subj":"T803","obj":"T805"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"events-check-again","denotations":[{"id":"T767","span":{"begin":13,"end":21},"obj":"Positive_regulation"},{"id":"T768","span":{"begin":22,"end":27},"obj":"Protein"},{"id":"T769","span":{"begin":28,"end":38},"obj":"Gene_expression"},{"id":"T770","span":{"begin":288,"end":306},"obj":"Protein"},{"id":"T771","span":{"begin":308,"end":313},"obj":"Protein"},{"id":"T772","span":{"begin":347,"end":356},"obj":"Localization"}],"relations":[{"id":"R645","pred":"themeOf","subj":"T768","obj":"T769"},{"id":"R646","pred":"themeOf","subj":"T769","obj":"T767"},{"id":"R647","pred":"equivalentTo","subj":"T771","obj":"T770"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"ICD10","denotations":[{"id":"T694","span":{"begin":266,"end":281},"obj":"http://purl.bioontology.org/ontology/ICD10/E84"},{"id":"T695","span":{"begin":266,"end":281},"obj":"http://purl.bioontology.org/ontology/ICD10/E84.9"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"GO-BP","denotations":[{"id":"T680","span":{"begin":128,"end":140},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T681","span":{"begin":288,"end":306},"obj":"http://purl.obolibrary.org/obo/GO_0050720"},{"id":"T682","span":{"begin":288,"end":306},"obj":"http://purl.obolibrary.org/obo/GO_0050702"},{"id":"T683","span":{"begin":300,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0032611"},{"id":"T684","span":{"begin":347,"end":356},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T378","span":{"begin":0,"end":21},"obj":"NNP"},{"id":"T379","span":{"begin":22,"end":27},"obj":"NNP"},{"id":"T380","span":{"begin":28,"end":38},"obj":"NN"},{"id":"T381","span":{"begin":39,"end":41},"obj":"IN"},{"id":"T382","span":{"begin":42,"end":48},"obj":"NNP"},{"id":"T383","span":{"begin":49,"end":53},"obj":"IN"},{"id":"T384","span":{"begin":54,"end":60},"obj":"NNP"},{"id":"T385","span":{"begin":61,"end":69},"obj":"NNP"},{"id":"T386","span":{"begin":117,"end":127},"obj":"NNP"},{"id":"T387","span":{"begin":128,"end":140},"obj":"NNP"},{"id":"T388","span":{"begin":141,"end":144},"obj":"CC"},{"id":"T389","span":{"begin":145,"end":154},"obj":"NN"},{"id":"T390","span":{"begin":155,"end":158},"obj":"VBP"},{"id":"T391","span":{"begin":159,"end":164},"obj":"JJ"},{"id":"T392","span":{"begin":165,"end":177},"obj":"NNS"},{"id":"T393","span":{"begin":178,"end":180},"obj":"IN"},{"id":"T394","span":{"begin":181,"end":188},"obj":"NN"},{"id":"T395","span":{"begin":189,"end":197},"obj":"NN"},{"id":"T396","span":{"begin":198,"end":201},"obj":"CC"},{"id":"T397","span":{"begin":202,"end":214},"obj":"RB"},{"id":"T398","span":{"begin":214,"end":215},"obj":","},{"id":"T399","span":{"begin":216,"end":219},"obj":"DT"},{"id":"T400","span":{"begin":220,"end":227},"obj":"NN"},{"id":"T401","span":{"begin":228,"end":230},"obj":"IN"},{"id":"T402","span":{"begin":231,"end":235},"obj":"NN"},{"id":"T403","span":{"begin":236,"end":239},"obj":"CC"},{"id":"T404","span":{"begin":240,"end":247},"obj":"NN"},{"id":"T405","span":{"begin":248,"end":251},"obj":"IN"},{"id":"T406","span":{"begin":252,"end":260},"obj":"NNS"},{"id":"T407","span":{"begin":261,"end":265},"obj":"IN"},{"id":"T408","span":{"begin":266,"end":272},"obj":"JJ"},{"id":"T409","span":{"begin":273,"end":281},"obj":"NN"},{"id":"T410","span":{"begin":282,"end":283},"obj":"-LRB-"},{"id":"T411","span":{"begin":283,"end":285},"obj":"NNP"},{"id":"T412","span":{"begin":285,"end":286},"obj":"-RRB-"},{"id":"T413","span":{"begin":286,"end":287},"obj":"."},{"id":"T414","span":{"begin":288,"end":301},"obj":"NN"},{"id":"T415","span":{"begin":302,"end":306},"obj":"NN"},{"id":"T416","span":{"begin":307,"end":308},"obj":"-LRB-"},{"id":"T417","span":{"begin":308,"end":313},"obj":"NN"},{"id":"T418","span":{"begin":313,"end":314},"obj":"-RRB-"},{"id":"T419","span":{"begin":315,"end":317},"obj":"VBZ"},{"id":"T420","span":{"begin":318,"end":319},"obj":"DT"},{"id":"T421","span":{"begin":320,"end":323},"obj":"JJ"},{"id":"T422","span":{"begin":324,"end":336},"obj":"JJ"},{"id":"T423","span":{"begin":337,"end":345},"obj":"NN"},{"id":"T424","span":{"begin":345,"end":346},"obj":"."},{"id":"T425","span":{"begin":347,"end":356},"obj":"NNP"},{"id":"T426","span":{"begin":357,"end":359},"obj":"IN"},{"id":"T427","span":{"begin":360,"end":372},"obj":"RB"},{"id":"T428","span":{"begin":373,"end":379},"obj":"JJ"}],"relations":[{"id":"R316","pred":"compound","subj":"T378","obj":"T380"},{"id":"R317","pred":"compound","subj":"T379","obj":"T380"},{"id":"R318","pred":"nsubj","subj":"T380","obj":"T390"},{"id":"R319","pred":"prep","subj":"T381","obj":"T380"},{"id":"R320","pred":"pobj","subj":"T382","obj":"T381"},{"id":"R321","pred":"prep","subj":"T383","obj":"T380"},{"id":"R322","pred":"amod","subj":"T384","obj":"T387"},{"id":"R323","pred":"compound","subj":"T385","obj":"T387"},{"id":"R324","pred":"compound","subj":"T386","obj":"T387"},{"id":"R325","pred":"pobj","subj":"T387","obj":"T383"},{"id":"R326","pred":"cc","subj":"T388","obj":"T387"},{"id":"R327","pred":"conj","subj":"T389","obj":"T387"},{"id":"R328","pred":"ROOT","subj":"T390","obj":"T390"},{"id":"R329","pred":"amod","subj":"T391","obj":"T392"},{"id":"R330","pred":"attr","subj":"T392","obj":"T390"},{"id":"R331","pred":"prep","subj":"T393","obj":"T392"},{"id":"R332","pred":"compound","subj":"T394","obj":"T395"},{"id":"R333","pred":"pobj","subj":"T395","obj":"T393"},{"id":"R334","pred":"cc","subj":"T396","obj":"T390"},{"id":"R335","pred":"advmod","subj":"T397","obj":"T400"},{"id":"R336","pred":"punct","subj":"T398","obj":"T400"},{"id":"R337","pred":"det","subj":"T399","obj":"T400"},{"id":"R338","pred":"conj","subj":"T400","obj":"T390"},{"id":"R339","pred":"prep","subj":"T401","obj":"T400"},{"id":"R340","pred":"pobj","subj":"T402","obj":"T401"},{"id":"R341","pred":"cc","subj":"T403","obj":"T402"},{"id":"R342","pred":"conj","subj":"T404","obj":"T400"},{"id":"R343","pred":"prep","subj":"T405","obj":"T400"},{"id":"R344","pred":"pobj","subj":"T406","obj":"T405"},{"id":"R345","pred":"prep","subj":"T407","obj":"T406"},{"id":"R346","pred":"compound","subj":"T408","obj":"T409"},{"id":"R347","pred":"pobj","subj":"T409","obj":"T407"},{"id":"R348","pred":"punct","subj":"T410","obj":"T411"},{"id":"R349","pred":"appos","subj":"T411","obj":"T409"},{"id":"R350","pred":"punct","subj":"T412","obj":"T400"},{"id":"R351","pred":"punct","subj":"T413","obj":"T390"},{"id":"R352","pred":"compound","subj":"T414","obj":"T415"},{"id":"R353","pred":"nsubj","subj":"T415","obj":"T419"},{"id":"R354","pred":"punct","subj":"T416","obj":"T417"},{"id":"R355","pred":"appos","subj":"T417","obj":"T415"},{"id":"R356","pred":"punct","subj":"T418","obj":"T417"},{"id":"R357","pred":"ROOT","subj":"T419","obj":"T419"},{"id":"R358","pred":"det","subj":"T420","obj":"T423"},{"id":"R359","pred":"amod","subj":"T421","obj":"T423"},{"id":"R360","pred":"amod","subj":"T422","obj":"T423"},{"id":"R361","pred":"attr","subj":"T423","obj":"T419"},{"id":"R362","pred":"punct","subj":"T424","obj":"T419"},{"id":"R364","pred":"prep","subj":"T426","obj":"T425"},{"id":"R365","pred":"advmod","subj":"T427","obj":"T428"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"pmc-enju-pas","denotations":[{"id":"T89","span":{"begin":0,"end":21},"obj":"JJ"},{"id":"T90","span":{"begin":22,"end":27},"obj":"NN"},{"id":"T91","span":{"begin":28,"end":38},"obj":"NN"},{"id":"T92","span":{"begin":39,"end":41},"obj":"IN"},{"id":"T93","span":{"begin":42,"end":48},"obj":"NN"},{"id":"T94","span":{"begin":49,"end":53},"obj":"IN"},{"id":"T95","span":{"begin":54,"end":60},"obj":"JJ"},{"id":"T96","span":{"begin":61,"end":69},"obj":"NN"},{"id":"T97","span":{"begin":117,"end":127},"obj":"NN"},{"id":"T98","span":{"begin":128,"end":140},"obj":"NN"},{"id":"T99","span":{"begin":141,"end":144},"obj":"CC"},{"id":"T100","span":{"begin":145,"end":154},"obj":"NN"},{"id":"T101","span":{"begin":155,"end":158},"obj":"VB"},{"id":"T102","span":{"begin":159,"end":164},"obj":"JJ"},{"id":"T103","span":{"begin":165,"end":177},"obj":"NN"},{"id":"T104","span":{"begin":178,"end":180},"obj":"IN"},{"id":"T105","span":{"begin":181,"end":188},"obj":"NN"},{"id":"T106","span":{"begin":189,"end":197},"obj":"NN"},{"id":"T107","span":{"begin":198,"end":201},"obj":"CC"},{"id":"T108","span":{"begin":202,"end":214},"obj":"RB"},{"id":"T109","span":{"begin":214,"end":215},"obj":"-COMMA-"},{"id":"T110","span":{"begin":216,"end":219},"obj":"DT"},{"id":"T111","span":{"begin":220,"end":227},"obj":"NN"},{"id":"T112","span":{"begin":228,"end":230},"obj":"IN"},{"id":"T113","span":{"begin":231,"end":235},"obj":"NN"},{"id":"T114","span":{"begin":236,"end":239},"obj":"CC"},{"id":"T115","span":{"begin":240,"end":247},"obj":"NN"},{"id":"T116","span":{"begin":248,"end":251},"obj":"IN"},{"id":"T117","span":{"begin":252,"end":260},"obj":"NN"},{"id":"T118","span":{"begin":261,"end":265},"obj":"IN"},{"id":"T119","span":{"begin":266,"end":272},"obj":"JJ"},{"id":"T120","span":{"begin":273,"end":281},"obj":"NN"},{"id":"T121","span":{"begin":282,"end":283},"obj":"-LRB-"},{"id":"T122","span":{"begin":283,"end":285},"obj":"NN"},{"id":"T123","span":{"begin":285,"end":286},"obj":"-RRB-"},{"id":"T124","span":{"begin":288,"end":301},"obj":"NN"},{"id":"T125","span":{"begin":302,"end":306},"obj":"NN"},{"id":"T126","span":{"begin":307,"end":308},"obj":"-LRB-"},{"id":"T127","span":{"begin":308,"end":313},"obj":"NN"},{"id":"T128","span":{"begin":313,"end":314},"obj":"-RRB-"},{"id":"T129","span":{"begin":315,"end":317},"obj":"VB"},{"id":"T130","span":{"begin":318,"end":319},"obj":"DT"},{"id":"T131","span":{"begin":320,"end":323},"obj":"JJ"},{"id":"T132","span":{"begin":324,"end":336},"obj":"JJ"},{"id":"T133","span":{"begin":337,"end":345},"obj":"NN"},{"id":"T134","span":{"begin":347,"end":356},"obj":"NN"},{"id":"T135","span":{"begin":357,"end":359},"obj":"IN"},{"id":"T136","span":{"begin":360,"end":372},"obj":"RB"},{"id":"T137","span":{"begin":373,"end":379},"obj":"JJ"}],"relations":[{"id":"R45","pred":"arg1Of","subj":"T91","obj":"T89"},{"id":"R46","pred":"arg1Of","subj":"T91","obj":"T90"},{"id":"R47","pred":"arg1Of","subj":"T91","obj":"T92"},{"id":"R48","pred":"arg2Of","subj":"T93","obj":"T92"},{"id":"R49","pred":"arg1Of","subj":"T93","obj":"T94"},{"id":"R50","pred":"arg2Of","subj":"T96","obj":"T94"},{"id":"R51","pred":"arg1Of","subj":"T96","obj":"T95"},{"id":"R52","pred":"arg1Of","subj":"T98","obj":"T99"},{"id":"R53","pred":"arg1Of","subj":"T99","obj":"T101"},{"id":"R54","pred":"arg2Of","subj":"T100","obj":"T99"},{"id":"R55","pred":"arg2Of","subj":"T103","obj":"T101"},{"id":"R56","pred":"arg1Of","subj":"T103","obj":"T102"},{"id":"R57","pred":"arg1Of","subj":"T103","obj":"T104"},{"id":"R58","pred":"arg1Of","subj":"T103","obj":"T108"},{"id":"R59","pred":"arg1Of","subj":"T103","obj":"T109"},{"id":"R60","pred":"arg1Of","subj":"T104","obj":"T107"},{"id":"R61","pred":"arg2Of","subj":"T106","obj":"T104"},{"id":"R62","pred":"arg1Of","subj":"T106","obj":"T105"},{"id":"R63","pred":"arg2Of","subj":"T108","obj":"T107"},{"id":"R64","pred":"arg2Of","subj":"T111","obj":"T109"},{"id":"R65","pred":"arg1Of","subj":"T111","obj":"T110"},{"id":"R66","pred":"arg1Of","subj":"T111","obj":"T112"},{"id":"R67","pred":"arg1Of","subj":"T111","obj":"T116"},{"id":"R68","pred":"arg1Of","subj":"T113","obj":"T114"},{"id":"R69","pred":"arg2Of","subj":"T114","obj":"T112"},{"id":"R70","pred":"arg2Of","subj":"T115","obj":"T114"},{"id":"R71","pred":"arg2Of","subj":"T117","obj":"T116"},{"id":"R72","pred":"arg1Of","subj":"T117","obj":"T118"},{"id":"R73","pred":"arg2Of","subj":"T120","obj":"T118"},{"id":"R74","pred":"arg1Of","subj":"T120","obj":"T119"},{"id":"R75","pred":"arg1Of","subj":"T120","obj":"T121"},{"id":"R76","pred":"arg2Of","subj":"T122","obj":"T121"},{"id":"R77","pred":"arg3Of","subj":"T123","obj":"T121"},{"id":"R78","pred":"arg1Of","subj":"T125","obj":"T124"},{"id":"R79","pred":"arg1Of","subj":"T125","obj":"T126"},{"id":"R80","pred":"arg1Of","subj":"T125","obj":"T129"},{"id":"R81","pred":"arg2Of","subj":"T127","obj":"T126"},{"id":"R82","pred":"arg3Of","subj":"T128","obj":"T126"},{"id":"R83","pred":"arg2Of","subj":"T133","obj":"T129"},{"id":"R84","pred":"arg1Of","subj":"T133","obj":"T130"},{"id":"R85","pred":"arg1Of","subj":"T133","obj":"T131"},{"id":"R86","pred":"arg1Of","subj":"T133","obj":"T132"},{"id":"R87","pred":"arg1Of","subj":"T134","obj":"T135"},{"id":"R89","pred":"arg1Of","subj":"T137","obj":"T136"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}

{"project":"sentences","denotations":[{"id":"T72","span":{"begin":0,"end":69},"obj":"Sentence"},{"id":"T73","span":{"begin":117,"end":127},"obj":"Sentence"},{"id":"T74","span":{"begin":128,"end":287},"obj":"Sentence"},{"id":"T75","span":{"begin":288,"end":346},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":105},"obj":"Sentence"},{"id":"T2","span":{"begin":108,"end":116},"obj":"Sentence"},{"id":"T3","span":{"begin":117,"end":127},"obj":"Sentence"},{"id":"T4","span":{"begin":128,"end":287},"obj":"Sentence"},{"id":"T5","span":{"begin":288,"end":346},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis \n\nAbstract\nBackground\nInflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-"}