Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis IL-1β Production in Cystic Fibrosis 

Abstract
Background
Inflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-