PMC:3279418 / 15185-15342 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T5178	0-2	PRP	denotes	We
T5179	3-7	RB	denotes	next
T5180	8-18	VB	denotes	determined
T5181	19-21	IN	denotes	if
T5182	22-31	VB	denotes	disrupted
T5183	32-37	NN	denotes	NF-κB
T5184	37-38	-COMMA-	denotes	,
T5185	39-48	NN	denotes	TBK1/IRF3
T5186	48-49	-COMMA-	denotes	,
T5187	50-56	CC	denotes	and/or
T5188	57-61	NN	denotes	MAPK
T5189	62-71	NN	denotes	signaling
T5190	72-75	MD	denotes	may
T5191	76-84	VB	denotes	underlie
T5192	85-88	DT	denotes	the
T5193	89-97	JJ	denotes	impaired
T5194	98-106	NN	denotes	cytokine
T5195	107-117	NN	denotes	production
T5196	118-122	IN	denotes	from
T5197	123-133	VB	denotes	stimulated
T5198	134-151	JJ	denotes	Sharpin-deficient
T5199	152-156	NN	denotes	BMDC
R4312	T5178	T5180	arg1Of	We,determined
R4313	T5180	T5179	arg1Of	determined,next
R4314	T5180	T5181	arg1Of	determined,if
R4315	T5183	T5182	arg2Of	NF-κB,disrupted
R4316	T5183	T5184	arg1Of	NF-κB,","
R4317	T5184	T5187	arg1Of	",",and/or
R4318	T5185	T5184	arg2Of	TBK1/IRF3,","
R4319	T5187	T5186	arg1Of	and/or,","
R4320	T5187	T5190	arg1Of	and/or,may
R4321	T5187	T5191	arg1Of	and/or,underlie
R4322	T5189	T5187	arg2Of	signaling,and/or
R4323	T5189	T5188	arg1Of	signaling,MAPK
R4324	T5191	T5181	arg2Of	underlie,if
R4325	T5191	T5190	arg2Of	underlie,may
R4326	T5195	T5191	arg2Of	production,underlie
R4327	T5195	T5192	arg1Of	production,the
R4328	T5195	T5193	arg1Of	production,impaired
R4329	T5195	T5194	arg1Of	production,cytokine
R4330	T5195	T5196	arg1Of	production,from
R4331	T5199	T5196	arg2Of	BMDC,from
R4332	T5199	T5197	arg2Of	BMDC,stimulated
R4333	T5199	T5198	arg1Of	BMDC,Sharpin-deficient

Id	Subject	Object	Predicate	Lexical cue
T4762	0-2	PRP	denotes	We
T4763	3-7	JJ	denotes	next
T4764	8-18	VBN	denotes	determined
T4765	19-21	IN	denotes	if
T4766	22-31	VBN	denotes	disrupted
T4767	32-37	NNP	denotes	NF-κB
T4768	37-38	,	denotes	,
T4769	39-48	CD	denotes	TBK1/IRF3
T4770	48-49	,	denotes	,
T4771	50-56	CC	denotes	and/or
T4772	57-61	NNP	denotes	MAPK
T4773	62-71	VBG	denotes	signaling
T4774	72-75	MD	denotes	may
T4775	76-84	VB	denotes	underlie
T4776	85-88	DT	denotes	the
T4777	89-97	VBN	denotes	impaired
T4778	98-106	NN	denotes	cytokine
T4779	107-117	NN	denotes	production
T4780	118-122	IN	denotes	from
T4781	123-133	VBN	denotes	stimulated
T4782	134-151	JJ	denotes	Sharpin-deficient
T4783	152-156	NNP	denotes	BMDC
T4784	156-157	.	denotes	.
R3897	T4762	T4764	nsubjpass	We,determined
R3898	T4763	T4764	advmod	next,determined
R3899	T4764	T4764	ROOT	determined,determined
R3900	T4765	T4766	mark	if,disrupted
R3901	T4766	T4764	advcl	disrupted,determined
R3902	T4767	T4766	dobj	NF-κB,disrupted
R3903	T4768	T4767	punct	",",NF-κB
R3904	T4769	T4767	appos	TBK1/IRF3,NF-κB
R3905	T4770	T4766	punct	",",disrupted
R3906	T4771	T4766	cc	and/or,disrupted
R3907	T4772	T4773	compound	MAPK,signaling
R3908	T4773	T4775	nsubj	signaling,underlie
R3909	T4774	T4775	aux	may,underlie
R3910	T4775	T4764	ccomp	underlie,determined
R3911	T4776	T4779	det	the,production
R3912	T4777	T4779	amod	impaired,production
R3913	T4778	T4779	compound	cytokine,production
R3914	T4779	T4775	dobj	production,underlie
R3915	T4780	T4779	prep	from,production
R3916	T4781	T4783	amod	stimulated,BMDC
R3917	T4782	T4783	compound	Sharpin-deficient,BMDC
R3918	T4783	T4780	pobj	BMDC,from
R3919	T4784	T4775	punct	.,underlie

Id	Subject	Object	Predicate	Lexical cue
T5378	98-117	http://purl.obolibrary.org/obo/GO_0001816	denotes	cytokine production
T5383	62-71	http://purl.obolibrary.org/obo/GO_0023052	denotes	signaling
T5401	39-43	http://purl.obolibrary.org/obo/GO_0008384	denotes	TBK1
T5405	57-61	http://purl.obolibrary.org/obo/GO_0004707	denotes	MAPK
T5410	57-71	http://purl.obolibrary.org/obo/GO_0000165	denotes	MAPK signaling

Id	Subject	Object	Predicate	Lexical cue
T5421	39-43	http://purl.obolibrary.org/obo/GO_0008384	denotes	TBK1
T5425	57-61	http://purl.obolibrary.org/obo/GO_0004707	denotes	MAPK

Id	Subject	Object	Predicate	Lexical cue
T4484	0-157	Sentence	denotes	We next determined if disrupted NF-κB, TBK1/IRF3, and/or MAPK signaling may underlie the impaired cytokine production from stimulated Sharpin-deficient BMDC.
T103	0-157	Sentence	denotes	We next determined if disrupted NF-κB, TBK1/IRF3, and/or MAPK signaling may underlie the impaired cytokine production from stimulated Sharpin-deficient BMDC.

Id	Subject	Object	Predicate	Lexical cue
T5597	39-43	Protein	denotes	TBK1
T5598	44-48	Protein	denotes	IRF3
T5599	134-141	Protein	denotes	Sharpin
T5600	142-151	Negative_regulation	denotes	deficient
R4526	T5599	T5600	themeOf	Sharpin,deficient

Id	Subject	Object	Predicate	Lexical cue
T5679	32-37	Protein	denotes	NF-κB
T5680	39-43	Protein	denotes	TBK1
T5681	44-48	Protein	denotes	IRF3
T5682	57-61	Protein	denotes	MAPK
T5683	134-141	Protein	denotes	Sharpin
T5684	142-151	Negative_regulation	denotes	deficient
R4567	T5683	T5684	themeOf	Sharpin,deficient

Id	Subject	Object	Predicate	Lexical cue
T4439	39-43	Protein	denotes	TBK1
T4440	44-48	Protein	denotes	IRF3
T4441	134-141	Protein	denotes	Sharpin
T4442	142-151	Negative_regulation	denotes	deficient
R3608	T4441	T4442	themeOf	Sharpin,deficient

Id	Subject	Object	Predicate	Lexical cue
T5334	39-43	Q9UHD2	denotes	TBK1
T5335	44-48	Q14653	denotes	IRF3
T5336	134-141	Q9H0F6	denotes	Sharpin

Id	Subject	Object	Predicate	Lexical cue
T4380	39-43	Protein	denotes	TBK1
T4381	44-48	Protein	denotes	IRF3
T4382	134-141	Protein	denotes	Sharpin
T4383	142-151	Negative_regulation	denotes	deficient
R3583	T4382	T4383	themeOf	Sharpin,deficient