PMC:3218875 / 31029-31312 JSONTXT

{"project":"testone","denotations":[{"id":"T17351","span":{"begin":240,"end":249},"obj":"Gene_expression"},{"id":"T17350","span":{"begin":208,"end":221},"obj":"Gene_expression"},{"id":"T17349","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T17331","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T17330","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T17329","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T17328","span":{"begin":26,"end":33},"obj":"Protein"}],"relations":[{"id":"R11377","pred":"themeOf","subj":"T17328","obj":"T17349"},{"id":"R11378","pred":"themeOf","subj":"T17329","obj":"T17350"},{"id":"R11379","pred":"themeOf","subj":"T17331","obj":"T17351"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T18239","span":{"begin":282,"end":283},"obj":"."},{"id":"T18238","span":{"begin":281,"end":282},"obj":"NNP"},{"id":"T18237","span":{"begin":276,"end":281},"obj":"CD"},{"id":"T18236","span":{"begin":275,"end":276},"obj":"NNP"},{"id":"T18235","span":{"begin":266,"end":274},"obj":"NNS"},{"id":"T18234","span":{"begin":263,"end":265},"obj":"NNP"},{"id":"T18206","span":{"begin":119,"end":120},"obj":","},{"id":"T18205","span":{"begin":118,"end":119},"obj":"NNP"},{"id":"T18204","span":{"begin":113,"end":118},"obj":"CD"},{"id":"T18203","span":{"begin":112,"end":113},"obj":"NNP"},{"id":"T18202","span":{"begin":105,"end":111},"obj":"NN"},{"id":"T18201","span":{"begin":96,"end":104},"obj":"JJ"},{"id":"T18200","span":{"begin":92,"end":95},"obj":"CC"},{"id":"T18199","span":{"begin":80,"end":91},"obj":"NNS"},{"id":"T18198","span":{"begin":71,"end":79},"obj":"JJ"},{"id":"T18197","span":{"begin":68,"end":70},"obj":"NNP"},{"id":"T18196","span":{"begin":65,"end":67},"obj":"IN"},{"id":"T18195","span":{"begin":58,"end":64},"obj":"NNS"},{"id":"T18194","span":{"begin":51,"end":57},"obj":"JJR"},{"id":"T18193","span":{"begin":48,"end":50},"obj":"IN"},{"id":"T18192","span":{"begin":38,"end":47},"obj":"VBN"},{"id":"T18191","span":{"begin":34,"end":37},"obj":"VBP"},{"id":"T18190","span":{"begin":26,"end":33},"obj":"NNP"},{"id":"T18189","span":{"begin":22,"end":25},"obj":"CC"},{"id":"T18188","span":{"begin":14,"end":21},"obj":"NNP"},{"id":"T18187","span":{"begin":9,"end":13},"obj":"DT"},{"id":"T18186","span":{"begin":7,"end":8},"obj":","},{"id":"T18185","span":{"begin":0,"end":7},"obj":"RB"},{"id":"T18233","span":{"begin":258,"end":262},"obj":"IN"},{"id":"T18232","span":{"begin":252,"end":257},"obj":"NNS"},{"id":"T18231","span":{"begin":250,"end":251},"obj":"NN"},{"id":"T18230","span":{"begin":234,"end":249},"obj":"JJ"},{"id":"T18229","span":{"begin":230,"end":233},"obj":"CC"},{"id":"T18228","span":{"begin":228,"end":229},"obj":"NNP"},{"id":"T18227","span":{"begin":225,"end":228},"obj":"NNP"},{"id":"T18226","span":{"begin":222,"end":224},"obj":"IN"},{"id":"T18225","span":{"begin":208,"end":221},"obj":"VBN"},{"id":"T18224","span":{"begin":203,"end":207},"obj":"RB"},{"id":"T18223","span":{"begin":200,"end":202},"obj":"VBZ"},{"id":"T18222","span":{"begin":191,"end":199},"obj":"NN"},{"id":"T18221","span":{"begin":189,"end":190},"obj":"."},{"id":"T18220","span":{"begin":188,"end":189},"obj":"NNP"},{"id":"T18219","span":{"begin":186,"end":188},"obj":"CD"},{"id":"T18218","span":{"begin":185,"end":186},"obj":"NNP"},{"id":"T18217","span":{"begin":176,"end":184},"obj":"NNS"},{"id":"T18216","span":{"begin":173,"end":175},"obj":"NNP"},{"id":"T18215","span":{"begin":170,"end":172},"obj":"IN"},{"id":"T18214","span":{"begin":164,"end":169},"obj":"NNS"},{"id":"T18213","span":{"begin":152,"end":163},"obj":"NN"},{"id":"T18212","span":{"begin":146,"end":151},"obj":"NN"},{"id":"T18211","span":{"begin":135,"end":145},"obj":"JJ"},{"id":"T18210","span":{"begin":132,"end":134},"obj":"IN"},{"id":"T18209","span":{"begin":129,"end":131},"obj":"IN"},{"id":"T18208","span":{"begin":124,"end":128},"obj":"RB"},{"id":"T18207","span":{"begin":121,"end":123},"obj":"RB"}],"relations":[{"id":"R12041","pred":"advmod","subj":"T18185","obj":"T18192"},{"id":"R12042","pred":"punct","subj":"T18186","obj":"T18192"},{"id":"R12043","pred":"preconj","subj":"T18187","obj":"T18188"},{"id":"R12044","pred":"nsubjpass","subj":"T18188","obj":"T18192"},{"id":"R12045","pred":"cc","subj":"T18189","obj":"T18188"},{"id":"R12046","pred":"conj","subj":"T18190","obj":"T18188"},{"id":"R12047","pred":"auxpass","subj":"T18191","obj":"T18192"},{"id":"R12048","pred":"ROOT","subj":"T18192","obj":"T18192"},{"id":"R12049","pred":"prep","subj":"T18193","obj":"T18192"},{"id":"R12050","pred":"amod","subj":"T18194","obj":"T18195"},{"id":"R12051","pred":"pobj","subj":"T18195","obj":"T18193"},{"id":"R12052","pred":"prep","subj":"T18196","obj":"T18195"},{"id":"R12053","pred":"pobj","subj":"T18197","obj":"T18196"},{"id":"R12054","pred":"amod","subj":"T18198","obj":"T18199"},{"id":"R12055","pred":"conj","subj":"T18199","obj":"T18195"},{"id":"R12056","pred":"cc","subj":"T18200","obj":"T18199"},{"id":"R12057","pred":"amod","subj":"T18201","obj":"T18202"},{"id":"R12058","pred":"compound","subj":"T18202","obj":"T18205"},{"id":"R12059","pred":"compound","subj":"T18203","obj":"T18205"},{"id":"R12060","pred":"compound","subj":"T18204","obj":"T18205"},{"id":"R12061","pred":"conj","subj":"T18205","obj":"T18199"},{"id":"R12062","pred":"punct","subj":"T18206","obj":"T18205"},{"id":"R12063","pred":"advmod","subj":"T18207","obj":"T18209"},{"id":"R12064","pred":"advmod","subj":"T18208","obj":"T18209"},{"id":"R12065","pred":"cc","subj":"T18209","obj":"T18193"},{"id":"R12066","pred":"prep","subj":"T18210","obj":"T18209"},{"id":"R12067","pred":"amod","subj":"T18211","obj":"T18214"},{"id":"R12068","pred":"compound","subj":"T18212","obj":"T18213"},{"id":"R12069","pred":"compound","subj":"T18213","obj":"T18214"},{"id":"R12070","pred":"pobj","subj":"T18214","obj":"T18210"},{"id":"R12071","pred":"prep","subj":"T18215","obj":"T18214"},{"id":"R12072","pred":"compound","subj":"T18216","obj":"T18217"},{"id":"R12073","pred":"pobj","subj":"T18217","obj":"T18215"},{"id":"R12074","pred":"nmod","subj":"T18218","obj":"T18220"},{"id":"R12075","pred":"nummod","subj":"T18219","obj":"T18220"},{"id":"R12076","pred":"dobj","subj":"T18220","obj":"T18192"},{"id":"R12077","pred":"punct","subj":"T18221","obj":"T18192"},{"id":"R12078","pred":"nsubjpass","subj":"T18222","obj":"T18225"},{"id":"R12079","pred":"auxpass","subj":"T18223","obj":"T18225"},{"id":"R12080","pred":"advmod","subj":"T18224","obj":"T18225"},{"id":"R12081","pred":"ROOT","subj":"T18225","obj":"T18225"},{"id":"R12082","pred":"prep","subj":"T18226","obj":"T18225"},{"id":"R12083","pred":"compound","subj":"T18227","obj":"T18228"},{"id":"R12084","pred":"pobj","subj":"T18228","obj":"T18226"},{"id":"R12085","pred":"cc","subj":"T18229","obj":"T18228"},{"id":"R12086","pred":"conj","subj":"T18230","obj":"T18228"},{"id":"R12087","pred":"compound","subj":"T18231","obj":"T18232"},{"id":"R12088","pred":"conj","subj":"T18232","obj":"T18225"},{"id":"R12089","pred":"prep","subj":"T18233","obj":"T18232"},{"id":"R12090","pred":"compound","subj":"T18234","obj":"T18235"},{"id":"R12091","pred":"pobj","subj":"T18235","obj":"T18233"},{"id":"R12092","pred":"quantmod","subj":"T18236","obj":"T18237"},{"id":"R12093","pred":"nummod","subj":"T18237","obj":"T18238"},{"id":"R12094","pred":"conj","subj":"T18238","obj":"T18232"},{"id":"R12095","pred":"punct","subj":"T18239","obj":"T18225"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"DLUT931","denotations":[{"id":"T18584","span":{"begin":240,"end":249},"obj":"Gene_expression"},{"id":"T18583","span":{"begin":208,"end":221},"obj":"Gene_expression"},{"id":"T18582","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T18564","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18563","span":{"begin":26,"end":33},"obj":"Protein"},{"id":"T18566","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T18565","span":{"begin":225,"end":228},"obj":"Protein"}],"relations":[{"id":"R12375","pred":"themeOf","subj":"T18563","obj":"T18582"},{"id":"R12376","pred":"themeOf","subj":"T18564","obj":"T18583"},{"id":"R12377","pred":"themeOf","subj":"T18565","obj":"T18584"},{"id":"R12378","pred":"themeOf","subj":"T18566","obj":"T18584"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T18507","span":{"begin":234,"end":239},"obj":"http://www.uniprot.org/uniprot/Q16552"},{"id":"T18506","span":{"begin":225,"end":228},"obj":"http://www.uniprot.org/uniprot/P01730"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T17528","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T17527","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T17526","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T17525","span":{"begin":26,"end":33},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"2_test","denotations":[{"id":"21639951-18383392-4289515","span":{"begin":113,"end":115},"obj":"18383392"},{"id":"21639951-18438844-4289516","span":{"begin":116,"end":118},"obj":"18438844"},{"id":"21639951-18759964-4289517","span":{"begin":186,"end":188},"obj":"18759964"},{"id":"21639951-20459811-4289518","span":{"begin":276,"end":278},"obj":"20459811"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"pmc-enju-pas","denotations":[{"id":"T17730","span":{"begin":269,"end":270},"obj":"-RRB-"},{"id":"T17729","span":{"begin":264,"end":269},"obj":"CD"},{"id":"T17728","span":{"begin":263,"end":264},"obj":"-LRB-"},{"id":"T17727","span":{"begin":254,"end":262},"obj":"NN"},{"id":"T17726","span":{"begin":252,"end":254},"obj":"NN"},{"id":"T17725","span":{"begin":247,"end":251},"obj":"IN"},{"id":"T17724","span":{"begin":242,"end":247},"obj":"NN"},{"id":"T17723","span":{"begin":241,"end":242},"obj":"NN"},{"id":"T17722","span":{"begin":226,"end":241},"obj":"JJ"},{"id":"T17721","span":{"begin":223,"end":226},"obj":"CC"},{"id":"T17720","span":{"begin":219,"end":223},"obj":"JJ"},{"id":"T17719","span":{"begin":217,"end":219},"obj":"IN"},{"id":"T17718","span":{"begin":204,"end":217},"obj":"VB"},{"id":"T17717","span":{"begin":200,"end":204},"obj":"RB"},{"id":"T17716","span":{"begin":197,"end":199},"obj":"VB"},{"id":"T17715","span":{"begin":189,"end":197},"obj":"NN"},{"id":"T17714","span":{"begin":188,"end":189},"obj":"-RRB-"},{"id":"T17713","span":{"begin":186,"end":188},"obj":"CD"},{"id":"T17712","span":{"begin":185,"end":186},"obj":"-LRB-"},{"id":"T17711","span":{"begin":176,"end":184},"obj":"NN"},{"id":"T17710","span":{"begin":173,"end":175},"obj":"NN"},{"id":"T17709","span":{"begin":170,"end":172},"obj":"IN"},{"id":"T17708","span":{"begin":164,"end":169},"obj":"NN"},{"id":"T17707","span":{"begin":152,"end":163},"obj":"JJ"},{"id":"T17706","span":{"begin":146,"end":151},"obj":"NN"},{"id":"T17705","span":{"begin":135,"end":145},"obj":"JJ"},{"id":"T17704","span":{"begin":132,"end":134},"obj":"IN"},{"id":"T17703","span":{"begin":129,"end":131},"obj":"IN"},{"id":"T17702","span":{"begin":124,"end":128},"obj":"RB"},{"id":"T17701","span":{"begin":121,"end":123},"obj":"RB"},{"id":"T17700","span":{"begin":119,"end":120},"obj":"-COMMA-"},{"id":"T17699","span":{"begin":118,"end":119},"obj":"-RRB-"},{"id":"T17698","span":{"begin":113,"end":118},"obj":"CD"},{"id":"T17697","span":{"begin":112,"end":113},"obj":"-LRB-"},{"id":"T17696","span":{"begin":105,"end":111},"obj":"NN"},{"id":"T17695","span":{"begin":96,"end":104},"obj":"JJ"},{"id":"T17694","span":{"begin":92,"end":95},"obj":"CC"},{"id":"T17693","span":{"begin":80,"end":91},"obj":"NN"},{"id":"T17692","span":{"begin":71,"end":79},"obj":"JJ"},{"id":"T17691","span":{"begin":68,"end":70},"obj":"NN"},{"id":"T17690","span":{"begin":65,"end":67},"obj":"IN"},{"id":"T17689","span":{"begin":58,"end":64},"obj":"NN"},{"id":"T17688","span":{"begin":51,"end":57},"obj":"JJ"},{"id":"T17687","span":{"begin":48,"end":50},"obj":"IN"},{"id":"T17686","span":{"begin":38,"end":47},"obj":"VB"},{"id":"T17685","span":{"begin":34,"end":37},"obj":"VB"},{"id":"T17684","span":{"begin":26,"end":33},"obj":"NN"},{"id":"T17683","span":{"begin":22,"end":25},"obj":"CC"},{"id":"T17682","span":{"begin":14,"end":21},"obj":"NN"},{"id":"T17681","span":{"begin":9,"end":13},"obj":"CC"},{"id":"T17680","span":{"begin":7,"end":8},"obj":"-COMMA-"},{"id":"T17679","span":{"begin":0,"end":7},"obj":"RB"}],"relations":[{"id":"R11577","pred":"arg1Of","subj":"T17682","obj":"T17683"},{"id":"R11578","pred":"arg1Of","subj":"T17683","obj":"T17681"},{"id":"R11579","pred":"arg1Of","subj":"T17683","obj":"T17685"},{"id":"R11580","pred":"arg2Of","subj":"T17683","obj":"T17686"},{"id":"R11581","pred":"arg2Of","subj":"T17684","obj":"T17683"},{"id":"R11582","pred":"arg2Of","subj":"T17686","obj":"T17685"},{"id":"R11583","pred":"arg1Of","subj":"T17686","obj":"T17687"},{"id":"R11584","pred":"arg1Of","subj":"T17686","obj":"T17704"},{"id":"R11585","pred":"arg1Of","subj":"T17686","obj":"T17712"},{"id":"R11586","pred":"arg1Of","subj":"T17687","obj":"T17703"},{"id":"R11587","pred":"arg2Of","subj":"T17689","obj":"T17687"},{"id":"R11588","pred":"arg1Of","subj":"T17689","obj":"T17688"},{"id":"R11589","pred":"arg1Of","subj":"T17689","obj":"T17690"},{"id":"R11590","pred":"arg1Of","subj":"T17693","obj":"T17691"},{"id":"R11591","pred":"arg1Of","subj":"T17693","obj":"T17692"},{"id":"R11592","pred":"arg1Of","subj":"T17693","obj":"T17694"},{"id":"R11593","pred":"arg2Of","subj":"T17694","obj":"T17690"},{"id":"R11594","pred":"arg2Of","subj":"T17696","obj":"T17694"},{"id":"R11595","pred":"arg1Of","subj":"T17696","obj":"T17695"},{"id":"R11596","pred":"arg1Of","subj":"T17696","obj":"T17697"},{"id":"R11597","pred":"arg2Of","subj":"T17698","obj":"T17697"},{"id":"R11598","pred":"arg3Of","subj":"T17699","obj":"T17697"},{"id":"R11599","pred":"arg1Of","subj":"T17703","obj":"T17700"},{"id":"R11600","pred":"arg1Of","subj":"T17703","obj":"T17701"},{"id":"R11601","pred":"arg1Of","subj":"T17703","obj":"T17702"},{"id":"R11602","pred":"arg2Of","subj":"T17704","obj":"T17703"},{"id":"R11603","pred":"arg2Of","subj":"T17708","obj":"T17704"},{"id":"R11604","pred":"arg1Of","subj":"T17708","obj":"T17705"},{"id":"R11605","pred":"arg1Of","subj":"T17708","obj":"T17706"},{"id":"R11606","pred":"arg1Of","subj":"T17708","obj":"T17707"},{"id":"R11607","pred":"arg1Of","subj":"T17708","obj":"T17709"},{"id":"R11608","pred":"arg2Of","subj":"T17711","obj":"T17709"},{"id":"R11609","pred":"arg1Of","subj":"T17711","obj":"T17710"},{"id":"R11610","pred":"arg2Of","subj":"T17713","obj":"T17712"},{"id":"R11611","pred":"arg3Of","subj":"T17714","obj":"T17712"},{"id":"R11612","pred":"arg1Of","subj":"T17715","obj":"T17716"},{"id":"R11613","pred":"arg2Of","subj":"T17715","obj":"T17718"},{"id":"R11614","pred":"arg1Of","subj":"T17718","obj":"T17679"},{"id":"R11615","pred":"arg1Of","subj":"T17718","obj":"T17680"},{"id":"R11616","pred":"modOf","subj":"T17718","obj":"T17685"},{"id":"R11617","pred":"arg2Of","subj":"T17718","obj":"T17716"},{"id":"R11618","pred":"arg1Of","subj":"T17718","obj":"T17717"},{"id":"R11619","pred":"arg1Of","subj":"T17718","obj":"T17719"},{"id":"R11620","pred":"arg1Of","subj":"T17720","obj":"T17721"},{"id":"R11621","pred":"arg2Of","subj":"T17722","obj":"T17721"},{"id":"R11622","pred":"arg2Of","subj":"T17724","obj":"T17719"},{"id":"R11623","pred":"arg1Of","subj":"T17724","obj":"T17720"},{"id":"R11624","pred":"arg1Of","subj":"T17724","obj":"T17722"},{"id":"R11625","pred":"arg1Of","subj":"T17724","obj":"T17723"},{"id":"R11626","pred":"arg1Of","subj":"T17724","obj":"T17725"},{"id":"R11627","pred":"arg2Of","subj":"T17727","obj":"T17725"},{"id":"R11628","pred":"arg1Of","subj":"T17727","obj":"T17726"},{"id":"R11629","pred":"arg1Of","subj":"T17727","obj":"T17728"},{"id":"R11630","pred":"arg2Of","subj":"T17729","obj":"T17728"},{"id":"R11631","pred":"arg3Of","subj":"T17730","obj":"T17728"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"UBERON-AE","denotations":[{"id":"T17435","span":{"begin":146,"end":151},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T17433","span":{"begin":105,"end":111},"obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"GO-MF","denotations":[{"id":"T18004","span":{"begin":234,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0030367"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"GO-CC","denotations":[{"id":"T18008","span":{"begin":252,"end":257},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T18007","span":{"begin":164,"end":169},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"sentences","denotations":[{"id":"T17442","span":{"begin":0,"end":283},"obj":"Sentence"},{"id":"T179","span":{"begin":0,"end":283},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"simple1","denotations":[{"id":"T18024","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T18023","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T18022","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18021","span":{"begin":26,"end":33},"obj":"Protein"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T18774","span":{"begin":208,"end":221},"obj":"Gene_expression"},{"id":"T18773","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T18757","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T18756","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T18755","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18754","span":{"begin":26,"end":33},"obj":"Protein"},{"id":"T18776","span":{"begin":240,"end":249},"obj":"Gene_expression"},{"id":"T18775","span":{"begin":208,"end":221},"obj":"Positive_regulation"}],"relations":[{"id":"R12436","pred":"themeOf","subj":"T18754","obj":"T18773"},{"id":"R12437","pred":"themeOf","subj":"T18755","obj":"T18774"},{"id":"R12438","pred":"themeOf","subj":"T18757","obj":"T18776"},{"id":"R12446","pred":"themeOf","subj":"T18774","obj":"T18775"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T18542","span":{"begin":240,"end":249},"obj":"Gene_expression"},{"id":"T18541","span":{"begin":208,"end":221},"obj":"Gene_expression"},{"id":"T18540","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T18524","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T18523","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T18522","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18521","span":{"begin":26,"end":33},"obj":"Protein"}],"relations":[{"id":"R12359","pred":"themeOf","subj":"T18521","obj":"T18540"},{"id":"R12360","pred":"themeOf","subj":"T18522","obj":"T18541"},{"id":"R12361","pred":"themeOf","subj":"T18524","obj":"T18542"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T18867","span":{"begin":0,"end":91},"obj":"Gene_expression"},{"id":"T18863","span":{"begin":191,"end":282},"obj":"Positive_regulation"},{"id":"T18862","span":{"begin":191,"end":282},"obj":"Gene_expression"},{"id":"T18845","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18844","span":{"begin":263,"end":265},"obj":"Protein"},{"id":"T18833","span":{"begin":26,"end":33},"obj":"Protein"},{"id":"T18825","span":{"begin":225,"end":282},"obj":"Entity"},{"id":"T18812","span":{"begin":68,"end":91},"obj":"Entity"},{"id":"T18806","span":{"begin":14,"end":21},"obj":"Entity"},{"id":"T18805","span":{"begin":68,"end":70},"obj":"Protein"},{"id":"T18791","span":{"begin":135,"end":189},"obj":"Entity"},{"id":"T18787","span":{"begin":173,"end":175},"obj":"Protein"}],"relations":[{"id":"R12454","pred":"themeOf","subj":"T18833","obj":"T18867"},{"id":"R12459","pred":"themeOf","subj":"T18845","obj":"T18862"},{"id":"R12460","pred":"themeOf","subj":"T18845","obj":"T18863"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T18615","span":{"begin":234,"end":249},"obj":"Gene_expression"},{"id":"T18614","span":{"begin":208,"end":221},"obj":"Positive_regulation"},{"id":"T18613","span":{"begin":225,"end":229},"obj":"Protein"},{"id":"T18612","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T18611","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T18610","span":{"begin":38,"end":47},"obj":"Gene_expression"},{"id":"T18609","span":{"begin":26,"end":33},"obj":"Protein"},{"id":"T18608","span":{"begin":14,"end":21},"obj":"Protein"}],"relations":[{"id":"R12396","pred":"themeOf","subj":"T18608","obj":"T18610"},{"id":"R12397","pred":"themeOf","subj":"T18609","obj":"T18611"},{"id":"R12398","pred":"themeOf","subj":"T18612","obj":"T18614"},{"id":"R12399","pred":"themeOf","subj":"T18613","obj":"T18615"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}

{"project":"test3","denotations":[{"id":"T17410","span":{"begin":240,"end":249},"obj":"Gene_expression"},{"id":"T17409","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T17408","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T17407","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T17406","span":{"begin":26,"end":33},"obj":"Protein"},{"id":"T17377","span":{"begin":234,"end":239},"obj":"Protein"},{"id":"T17376","span":{"begin":225,"end":228},"obj":"Protein"},{"id":"T17375","span":{"begin":191,"end":199},"obj":"Protein"},{"id":"T17374","span":{"begin":26,"end":33},"obj":"Protein"}],"relations":[{"id":"R11392","pred":"themeOf","subj":"T17409","obj":"T17410"}],"text":"Notably, both miR-146 and miR-155 are expressed at higher levels in RA synovial fibroblasts and synovial tissue [81,82], as well as in peripheral blood mononuclear cells of RA patients [83]. miR-146a is also overexpressed in CD4+ and IL-17-producing T cells from RA patients [84,85]."}