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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2854337","sourcedb":"PMC","sourceid":"2854337","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2854337","text":"The recent spread of avian influenza A (H5N1) in wild and domestic poultry has raised global concern over a pandemic outbreak in humans [1]. Since 2003, about 450 cases of avian influenza A (H5N1) infection in humans have been reported in 15 countries, mainly in Southeast Asia [2]. In the study reported here, we have attempted to predict the effectiveness of intervention strategies against an epidemic of a novel influenza that will be caused by new strains of influenza achieving the same transmission ability in humans as avian influenza A (H5N1) by simulating various scenarios targeting Sapporo city, the capital of Hokkaido in Japan, with a population of about 1.9 million. Influenza A (H1N1), which is a new flu virus of swine origin, was first detected in Mexico in March 2009 [3] and has spread rapidly across the globe. A total of 209,438 cases of influenza A (H1N1) infection in over 170 countries, including 2,185 deaths, had been officially reported by late August 2009 [4]. The Ministry of Health, Labor, and Welfare of Japan [5] designed a “Pandemic Influenza Preparedness Action Plan” which, among other measures, includes the administration of antiviral drugs and school closure in the case of an influenza pandemic.","tracks":[{"project":"MyTest","denotations":[{"id":"19941171-12669040-28350059","span":{"begin":137,"end":138},"obj":"12669040"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"19941171-12669040-28350059","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"19941171-12669040-28350059","span":{"begin":137,"end":138},"obj":"12669040"}],"attributes":[{"subj":"19941171-12669040-28350059","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"MyTest","color":"#ec9b93","default":true},{"id":"2_test","color":"#93a5ec"}]}]}}