PMC:2854337 / 1799-3034 JSONTXT

{"project":"MyTest","denotations":[{"id":"19941171-12669040-28350059","span":{"begin":137,"end":138},"obj":"12669040"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The recent spread of avian influenza A (H5N1) in wild and domestic poultry has raised global concern over a pandemic outbreak in humans [1]. Since 2003, about 450 cases of avian influenza A (H5N1) infection in humans have been reported in 15 countries, mainly in Southeast Asia [2]. In the study reported here, we have attempted to predict the effectiveness of intervention strategies against an epidemic of a novel influenza that will be caused by new strains of influenza achieving the same transmission ability in humans as avian influenza A (H5N1) by simulating various scenarios targeting Sapporo city, the capital of Hokkaido in Japan, with a population of about 1.9 million. Influenza A (H1N1), which is a new flu virus of swine origin, was first detected in Mexico in March 2009 [3] and has spread rapidly across the globe. A total of 209,438 cases of influenza A (H1N1) infection in over 170 countries, including 2,185 deaths, had been officially reported by late August 2009 [4]. The Ministry of Health, Labor, and Welfare of Japan [5] designed a “Pandemic Influenza Preparedness Action Plan” which, among other measures, includes the administration of antiviral drugs and school closure in the case of an influenza pandemic."}

{"project":"2_test","denotations":[{"id":"19941171-12669040-28350059","span":{"begin":137,"end":138},"obj":"12669040"}],"text":"The recent spread of avian influenza A (H5N1) in wild and domestic poultry has raised global concern over a pandemic outbreak in humans [1]. Since 2003, about 450 cases of avian influenza A (H5N1) infection in humans have been reported in 15 countries, mainly in Southeast Asia [2]. In the study reported here, we have attempted to predict the effectiveness of intervention strategies against an epidemic of a novel influenza that will be caused by new strains of influenza achieving the same transmission ability in humans as avian influenza A (H5N1) by simulating various scenarios targeting Sapporo city, the capital of Hokkaido in Japan, with a population of about 1.9 million. Influenza A (H1N1), which is a new flu virus of swine origin, was first detected in Mexico in March 2009 [3] and has spread rapidly across the globe. A total of 209,438 cases of influenza A (H1N1) infection in over 170 countries, including 2,185 deaths, had been officially reported by late August 2009 [4]. The Ministry of Health, Labor, and Welfare of Japan [5] designed a “Pandemic Influenza Preparedness Action Plan” which, among other measures, includes the administration of antiviral drugs and school closure in the case of an influenza pandemic."}