PMC:2726282 / 29259-30815 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2726282","sourcedb":"PMC","sourceid":"2726282","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2726282","text":"Table 1 Distributions of positive, negative and dual (auto)regulatory interactions, mean path length16 and observed maximum out- and in-degrees for different sections of the E. coli transcriptional cross-regulatory network shown in Fig. 1\nNetwork section No. of TFs Autoregulations Positive autoregulations Negative autoregulations Dual autoregulation Regulatory arcsa Positive arcs Negative arcs Dual arcs Average path lengthb Maximum out-degreec Maximum in-degreec\nAll 115 80 (70) 24 (30) 48 (60) 8 (10) 166 90 (54) 67 (40) 9 (6) 2.74 42 9\nCarbon sources 24 19 (79) 5 (26) 9 (48) 5 (26) 27 20 (74) 6 (22) 1 (4) 1.53 20 2\nBiofilm and motilityd 32 18 (56) 9 (50) 9 (50) 0 52 22 (42) 27 (52) 3 (6) 3.12 8 9\nValues in parentheses are percentages. Subnetworks for alternative carbon sources and for biofilm and chemotaxis development processes are defined in Fig. 2a. Note that while the carbon sources module has a relatively high maximum out-degree compared to the biofilm/motility module, the latter has a higher maximum in-degree, clearly suggesting that the motility TF, flhCD (with nine inputs), is directed by several TFs to control its regulation.\na Regulatory interactions from TFs to others TFs or towards sigma factors.\nb Average path lengths in the (sub)network(s) were calculated with the ViSANT program.16\nc Excluding sigmas.\nd Only the TFs forming cascades ending on biofilm and chemotaxis modules were computed, the autoregulation of CRP was computed in the carbon sources module (Fig. 2a).","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":239}},{"label":"p","span":{"begin":9,"end":239}},{"label":"table","span":{"begin":240,"end":754}},{"label":"tr","span":{"begin":240,"end":479}},{"label":"th","span":{"begin":240,"end":255}},{"label":"th","span":{"begin":257,"end":267}},{"label":"th","span":{"begin":269,"end":284}},{"label":"th","span":{"begin":286,"end":310}},{"label":"th","span":{"begin":312,"end":336}},{"label":"th","span":{"begin":338,"end":357}},{"label":"th","span":{"begin":359,"end":375}},{"label":"th","span":{"begin":377,"end":390}},{"label":"th","span":{"begin":392,"end":405}},{"label":"th","span":{"begin":407,"end":416}},{"label":"th","span":{"begin":418,"end":438}},{"label":"th","span":{"begin":440,"end":459}},{"label":"th","span":{"begin":461,"end":479}},{"label":"tr","span":{"begin":480,"end":566}},{"label":"td","span":{"begin":480,"end":483}},{"label":"td","span":{"begin":485,"end":488}},{"label":"td","span":{"begin":490,"end":497}},{"label":"td","span":{"begin":499,"end":506}},{"label":"td","span":{"begin":508,"end":515}},{"label":"td","span":{"begin":517,"end":523}},{"label":"td","span":{"begin":525,"end":528}},{"label":"td","span":{"begin":530,"end":537}},{"label":"td","span":{"begin":539,"end":546}},{"label":"td","span":{"begin":548,"end":553}},{"label":"td","span":{"begin":555,"end":559}},{"label":"td","span":{"begin":561,"end":563}},{"label":"td","span":{"begin":565,"end":566}},{"label":"tr","span":{"begin":567,"end":659}},{"label":"td","span":{"begin":567,"end":581}},{"label":"td","span":{"begin":583,"end":585}},{"label":"td","span":{"begin":587,"end":594}},{"label":"td","span":{"begin":596,"end":602}},{"label":"td","span":{"begin":604,"end":610}},{"label":"td","span":{"begin":612,"end":618}},{"label":"td","span":{"begin":620,"end":622}},{"label":"td","span":{"begin":624,"end":631}},{"label":"td","span":{"begin":633,"end":639}},{"label":"td","span":{"begin":641,"end":646}},{"label":"td","span":{"begin":648,"end":652}},{"label":"td","span":{"begin":654,"end":656}},{"label":"td","span":{"begin":658,"end":659}},{"label":"tr","span":{"begin":660,"end":754}},{"label":"td","span":{"begin":660,"end":681}},{"label":"td","span":{"begin":683,"end":685}},{"label":"td","span":{"begin":687,"end":694}},{"label":"td","span":{"begin":696,"end":702}},{"label":"td","span":{"begin":704,"end":710}},{"label":"td","span":{"begin":712,"end":713}},{"label":"td","span":{"begin":715,"end":717}},{"label":"td","span":{"begin":719,"end":726}},{"label":"td","span":{"begin":728,"end":735}},{"label":"td","span":{"begin":737,"end":742}},{"label":"td","span":{"begin":744,"end":748}},{"label":"td","span":{"begin":750,"end":751}},{"label":"td","span":{"begin":753,"end":754}},{"label":"table-wrap-foot","span":{"begin":755,"end":1201}},{"label":"footnote","span":{"begin":755,"end":1201}},{"label":"p","span":{"begin":755,"end":1201}},{"label":"table-wrap-foot","span":{"begin":1202,"end":1277}},{"label":"footnote","span":{"begin":1202,"end":1277}},{"label":"label","span":{"begin":1202,"end":1203}},{"label":"p","span":{"begin":1205,"end":1277}},{"label":"table-wrap-foot","span":{"begin":1278,"end":1367}},{"label":"footnote","span":{"begin":1278,"end":1367}},{"label":"label","span":{"begin":1278,"end":1279}},{"label":"p","span":{"begin":1281,"end":1367}},{"label":"table-wrap-foot","span":{"begin":1368,"end":1388}},{"label":"footnote","span":{"begin":1368,"end":1388}},{"label":"label","span":{"begin":1368,"end":1369}},{"label":"p","span":{"begin":1371,"end":1388}},{"label":"label","span":{"begin":1389,"end":1390}}],"tracks":[]}