PMC:2674207 / 914-1802
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T241 | 0-7 | NN | denotes | Methods |
T242 | 8-11 | CC | denotes | and |
T243 | 12-20 | NN | denotes | Findings |
T244 | 21-23 | IN | denotes | In |
T245 | 24-25 | DT | denotes | a |
T246 | 26-27 | NN | denotes | T |
T247 | 28-38 | NN | denotes | lymphocyte |
T248 | 39-43 | NN | denotes | cell |
T249 | 44-48 | NN | denotes | line |
T250 | 49-50 | -LRB- | denotes | ( |
T251 | 50-56 | NN | denotes | HuT-78 |
T252 | 56-57 | -RRB- | denotes | ) |
T253 | 58-61 | CC | denotes | and |
T254 | 62-72 | JJ | denotes | peripheral |
T255 | 73-78 | NN | denotes | blood |
T256 | 79-90 | JJ | denotes | mononuclear |
T257 | 91-96 | NN | denotes | cells |
T258 | 97-107 | VB | denotes | stimulated |
T259 | 108-110 | IN | denotes | by |
T260 | 111-119 | JJ | denotes | anti-CD3 |
T261 | 120-123 | CC | denotes | and |
T262 | 124-133 | JJ | denotes | anti-CD28 |
T263 | 134-136 | FW | denotes | in |
T264 | 137-142 | FW | denotes | vitro |
T265 | 143-145 | PRP | denotes | we |
T266 | 146-158 | VB | denotes | demonstrated |
T267 | 159-163 | IN | denotes | that |
T268 | 164-175 | NN | denotes | fluticasone |
T269 | 176-184 | VB | denotes | inhibits |
T270 | 185-192 | JJ | denotes | nuclear |
T271 | 193-206 | NN | denotes | translocation |
T272 | 207-209 | IN | denotes | of |
T273 | 210-216 | NN | denotes | GATA-3 |
T274 | 217-220 | CC | denotes | and |
T275 | 221-231 | NN | denotes | expression |
T276 | 232-234 | IN | denotes | of |
T277 | 235-238 | NN | denotes | Th2 |
T278 | 239-248 | NN | denotes | cytokines |
T279 | 249-252 | IN | denotes | via |
T280 | 253-254 | DT | denotes | a |
T281 | 255-264 | NN | denotes | mechanism |
T282 | 265-276 | JJ | denotes | independent |
T283 | 277-279 | IN | denotes | of |
T284 | 280-287 | JJ | denotes | nuclear |
T285 | 288-297 | NN | denotes | factor-κB |
T286 | 298-301 | CC | denotes | and |
T287 | 302-304 | VB | denotes | is |
T288 | 305-308 | JJ | denotes | due |
T289 | 308-309 | -COMMA- | denotes | , |
T290 | 310-312 | IN | denotes | in |
T291 | 313-317 | NN | denotes | part |
T292 | 317-318 | -COMMA- | denotes | , |
T293 | 319-321 | TO | denotes | to |
T294 | 322-333 | NN | denotes | competition |
T295 | 334-341 | IN | denotes | between |
T296 | 342-348 | NN | denotes | GATA-3 |
T297 | 349-352 | CC | denotes | and |
T298 | 353-356 | DT | denotes | the |
T299 | 357-373 | JJ | denotes | ligand-activated |
T300 | 374-388 | NN | denotes | glucocorticoid |
T301 | 389-397 | NN | denotes | receptor |
T302 | 398-401 | IN | denotes | for |
T303 | 402-409 | JJ | denotes | nuclear |
T304 | 410-419 | NN | denotes | transport |
T305 | 420-427 | IN | denotes | through |
T306 | 428-431 | DT | denotes | the |
T307 | 432-439 | JJ | denotes | nuclear |
T308 | 440-448 | NN | denotes | importer |
T309 | 449-459 | NN | denotes | importin-α |
T310 | 461-463 | IN | denotes | In |
T311 | 464-472 | NN | denotes | addition |
T312 | 472-473 | -COMMA- | denotes | , |
T313 | 474-485 | NN | denotes | fluticasone |
T314 | 486-493 | VB | denotes | induces |
T315 | 494-497 | DT | denotes | the |
T316 | 498-508 | NN | denotes | expression |
T317 | 509-511 | IN | denotes | of |
T318 | 512-529 | JJ | denotes | mitogen-activated |
T319 | 530-537 | NN | denotes | protein |
T320 | 538-544 | NN | denotes | kinase |
T321 | 545-546 | -LRB- | denotes | ( |
T322 | 546-550 | NN | denotes | MAPK |
T323 | 550-551 | -RRB- | denotes | ) |
T324 | 552-565 | NN | denotes | phosphatase-1 |
T325 | 566-567 | -LRB- | denotes | ( |
T326 | 567-572 | NN | denotes | MKP-1 |
T327 | 572-573 | -RRB- | denotes | ) |
T328 | 573-574 | -COMMA- | denotes | , |
T329 | 575-578 | DT | denotes | the |
T330 | 579-589 | JJ | denotes | endogenous |
T331 | 590-599 | NN | denotes | inhibitor |
T332 | 600-602 | IN | denotes | of |
T333 | 603-606 | NN | denotes | p38 |
T334 | 607-611 | NN | denotes | MAPK |
T335 | 611-612 | -COMMA- | denotes | , |
T336 | 613-618 | WDT | denotes | which |
T337 | 619-621 | VB | denotes | is |
T338 | 622-631 | JJ | denotes | necessary |
T339 | 632-635 | IN | denotes | for |
T340 | 636-642 | NN | denotes | GATA-3 |
T341 | 643-650 | JJ | denotes | nuclear |
T342 | 651-664 | NN | denotes | translocation |
T343 | 666-671 | DT | denotes | These |
T344 | 672-682 | JJ | denotes | inhibitory |
T345 | 683-690 | NN | denotes | effects |
T346 | 691-693 | IN | denotes | of |
T347 | 694-705 | NN | denotes | fluticasone |
T348 | 706-709 | VB | denotes | are |
T349 | 710-715 | JJ | denotes | rapid |
T350 | 715-716 | -COMMA- | denotes | , |
T351 | 717-723 | JJ | denotes | potent |
T352 | 723-724 | -COMMA- | denotes | , |
T353 | 725-728 | CC | denotes | and |
T354 | 729-738 | VB | denotes | prolonged |
T355 | 740-742 | PRP | denotes | We |
T356 | 743-747 | RB | denotes | also |
T357 | 748-760 | VB | denotes | demonstrated |
T358 | 761-765 | IN | denotes | that |
T359 | 766-773 | VB | denotes | inhaled |
T360 | 774-785 | NN | denotes | fluticasone |
T361 | 786-794 | VB | denotes | inhibits |
T362 | 795-801 | NN | denotes | GATA-3 |
T363 | 802-809 | JJ | denotes | nuclear |
T364 | 810-823 | NN | denotes | translocation |
T365 | 824-826 | IN | denotes | in |
T366 | 827-837 | JJ | denotes | peripheral |
T367 | 838-843 | NN | denotes | blood |
T368 | 844-855 | NN | denotes | lymphocytes |
T369 | 856-858 | IN | denotes | of |
T370 | 859-867 | NN | denotes | patients |
T371 | 868-872 | IN | denotes | with |
T372 | 873-879 | NN | denotes | asthma |
T373 | 880-882 | FW | denotes | in |
T374 | 883-887 | FW | denotes | vivo |
R191 | T241 | T242 | arg1Of | Methods,and |
R192 | T243 | T242 | arg2Of | Findings,and |
R193 | T249 | T246 | arg1Of | line,T |
R194 | T249 | T247 | arg1Of | line,lymphocyte |
R195 | T249 | T248 | arg1Of | line,cell |
R196 | T249 | T250 | arg1Of | line,( |
R197 | T249 | T253 | arg1Of | line,and |
R198 | T251 | T250 | arg2Of | HuT-78,( |
R199 | T252 | T250 | arg3Of | ),( |
R200 | T253 | T244 | arg2Of | and,In |
R201 | T253 | T245 | arg1Of | and,a |
R202 | T253 | T264 | arg1Of | and,vitro |
R203 | T257 | T253 | arg2Of | cells,and |
R204 | T257 | T254 | arg1Of | cells,peripheral |
R205 | T257 | T255 | arg1Of | cells,blood |
R206 | T257 | T256 | arg1Of | cells,mononuclear |
R207 | T257 | T258 | arg2Of | cells,stimulated |
R208 | T260 | T261 | arg1Of | anti-CD3,and |
R209 | T261 | T258 | arg1Of | and,stimulated |
R210 | T261 | T259 | arg2Of | and,by |
R211 | T262 | T261 | arg2Of | anti-CD28,and |
R212 | T264 | T263 | arg1Of | vitro,in |
R213 | T265 | T266 | arg1Of | we,demonstrated |
R214 | T266 | T244 | arg1Of | demonstrated,In |
R215 | T268 | T269 | arg1Of | fluticasone,inhibits |
R216 | T268 | T287 | arg1Of | fluticasone,is |
R217 | T268 | T288 | arg1Of | fluticasone,due |
R218 | T269 | T279 | arg1Of | inhibits,via |
R219 | T269 | T286 | arg1Of | inhibits,and |
R220 | T271 | T270 | arg1Of | translocation,nuclear |
R221 | T271 | T272 | arg1Of | translocation,of |
R222 | T271 | T274 | arg1Of | translocation,and |
R223 | T273 | T272 | arg2Of | GATA-3,of |
R224 | T274 | T269 | arg2Of | and,inhibits |
R225 | T275 | T274 | arg2Of | expression,and |
R226 | T275 | T276 | arg1Of | expression,of |
R227 | T278 | T276 | arg2Of | cytokines,of |
R228 | T278 | T277 | arg1Of | cytokines,Th2 |
R229 | T281 | T279 | arg2Of | mechanism,via |
R230 | T281 | T280 | arg1Of | mechanism,a |
R231 | T281 | T282 | arg1Of | mechanism,independent |
R232 | T282 | T283 | arg1Of | independent,of |
R233 | T285 | T283 | arg2Of | factor-κB,of |
R234 | T285 | T284 | arg1Of | factor-κB,nuclear |
R235 | T286 | T266 | arg2Of | and,demonstrated |
R236 | T286 | T267 | arg1Of | and,that |
R237 | T287 | T286 | arg2Of | is,and |
R238 | T287 | T292 | arg1Of | is,"," |
R239 | T287 | T293 | arg1Of | is,to |
R240 | T288 | T287 | arg2Of | due,is |
R241 | T288 | T289 | arg1Of | due,"," |
R242 | T288 | T290 | arg1Of | due,in |
R243 | T291 | T290 | arg2Of | part,in |
R244 | T294 | T293 | arg2Of | competition,to |
R245 | T294 | T295 | arg1Of | competition,between |
R246 | T296 | T297 | arg1Of | GATA-3,and |
R247 | T297 | T295 | arg2Of | and,between |
R248 | T301 | T297 | arg2Of | receptor,and |
R249 | T301 | T298 | arg1Of | receptor,the |
R250 | T301 | T299 | arg1Of | receptor,ligand-activated |
R251 | T301 | T300 | arg1Of | receptor,glucocorticoid |
R252 | T353 | T348 | arg2Of | and,are |
R253 | T353 | T352 | arg1Of | and,"," |
R254 | T301 | T302 | arg1Of | receptor,for |
R255 | T301 | T305 | arg1Of | receptor,through |
R256 | T304 | T302 | arg2Of | transport,for |
R257 | T354 | T353 | arg2Of | prolonged,and |
R258 | T355 | T357 | arg1Of | We,demonstrated |
R259 | T357 | T356 | arg1Of | demonstrated,also |
R260 | T360 | T359 | arg2Of | fluticasone,inhaled |
R261 | T360 | T361 | arg1Of | fluticasone,inhibits |
R262 | T304 | T303 | arg1Of | transport,nuclear |
R263 | T361 | T357 | arg2Of | inhibits,demonstrated |
R264 | T361 | T358 | arg1Of | inhibits,that |
R265 | T309 | T305 | arg2Of | importin-α,through |
R266 | T364 | T361 | arg2Of | translocation,inhibits |
R267 | T364 | T362 | arg1Of | translocation,GATA-3 |
R268 | T364 | T363 | arg1Of | translocation,nuclear |
R269 | T364 | T365 | arg1Of | translocation,in |
R270 | T368 | T365 | arg2Of | lymphocytes,in |
R271 | T368 | T366 | arg1Of | lymphocytes,peripheral |
R272 | T368 | T367 | arg1Of | lymphocytes,blood |
R273 | T368 | T369 | arg1Of | lymphocytes,of |
R274 | T370 | T369 | arg2Of | patients,of |
R275 | T370 | T371 | arg1Of | patients,with |
R276 | T309 | T306 | arg1Of | importin-α,the |
R277 | T372 | T371 | arg2Of | asthma,with |
R278 | T372 | T374 | arg1Of | asthma,vivo |
R279 | T309 | T307 | arg1Of | importin-α,nuclear |
R280 | T309 | T308 | arg1Of | importin-α,importer |
R281 | T374 | T373 | arg1Of | vivo,in |
R282 | T311 | T310 | arg2Of | addition,In |
R285 | T313 | T314 | arg1Of | fluticasone,induces |
R290 | T314 | T310 | arg1Of | induces,In |
R293 | T314 | T312 | arg1Of | induces,"," |
R294 | T316 | T314 | arg2Of | expression,induces |
R301 | T316 | T315 | arg1Of | expression,the |
R302 | T316 | T317 | arg1Of | expression,of |
R303 | T320 | T318 | arg1Of | kinase,mitogen-activated |
R317 | T320 | T319 | arg1Of | kinase,protein |
R318 | T320 | T321 | arg1Of | kinase,( |
R319 | T322 | T321 | arg2Of | MAPK,( |
R327 | T323 | T321 | arg3Of | ),( |
R331 | T324 | T317 | arg2Of | phosphatase-1,of |
R335 | T324 | T320 | arg1Of | phosphatase-1,kinase |
R336 | T324 | T325 | arg1Of | phosphatase-1,( |
R337 | T324 | T328 | arg1Of | phosphatase-1,"," |
R338 | T326 | T325 | arg2Of | MKP-1,( |
R339 | T327 | T325 | arg3Of | ),( |
R340 | T331 | T328 | arg2Of | inhibitor,"," |
R342 | T331 | T329 | arg1Of | inhibitor,the |
R343 | T331 | T330 | arg1Of | inhibitor,endogenous |
R344 | T331 | T332 | arg1Of | inhibitor,of |
R345 | T334 | T332 | arg2Of | MAPK,of |
R346 | T334 | T333 | arg1Of | MAPK,p38 |
R347 | T334 | T335 | arg1Of | MAPK,"," |
R348 | T334 | T336 | arg1Of | MAPK,which |
R349 | T334 | T337 | arg1Of | MAPK,is |
R350 | T334 | T338 | arg1Of | MAPK,necessary |
R351 | T338 | T337 | arg2Of | necessary,is |
R353 | T338 | T339 | arg1Of | necessary,for |
R354 | T342 | T339 | arg2Of | translocation,for |
R361 | T342 | T340 | arg1Of | translocation,GATA-3 |
R362 | T342 | T341 | arg1Of | translocation,nuclear |
R363 | T345 | T343 | arg1Of | effects,These |
R364 | T345 | T344 | arg1Of | effects,inhibitory |
R365 | T345 | T346 | arg1Of | effects,of |
R366 | T345 | T348 | arg1Of | effects,are |
R367 | T345 | T349 | arg1Of | effects,rapid |
R368 | T345 | T351 | arg1Of | effects,potent |
R369 | T345 | T354 | arg1Of | effects,prolonged |
R370 | T347 | T346 | arg2Of | fluticasone,of |
R371 | T349 | T350 | arg1Of | rapid,"," |
R372 | T350 | T353 | arg1Of | ",",and |
R373 | T351 | T350 | arg2Of | potent,"," |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T549 | 0-7 | NNS | denotes | Methods |
T550 | 8-11 | CC | denotes | and |
T551 | 12-20 | NNS | denotes | Findings |
T552 | 21-23 | IN | denotes | In |
T553 | 24-25 | DT | denotes | a |
T554 | 26-27 | NNP | denotes | T |
T555 | 28-38 | NN | denotes | lymphocyte |
T556 | 39-43 | NN | denotes | cell |
T557 | 44-48 | NN | denotes | line |
T558 | 49-50 | -LRB- | denotes | ( |
T559 | 50-56 | JJ | denotes | HuT-78 |
T560 | 56-57 | -RRB- | denotes | ) |
T561 | 58-61 | CC | denotes | and |
T562 | 62-72 | JJ | denotes | peripheral |
T563 | 73-78 | NN | denotes | blood |
T564 | 79-90 | NN | denotes | mononuclear |
T565 | 91-96 | NNS | denotes | cells |
T566 | 97-107 | VBN | denotes | stimulated |
T567 | 108-110 | IN | denotes | by |
T568 | 111-119 | JJ | denotes | anti-CD3 |
T569 | 120-123 | CC | denotes | and |
T570 | 124-133 | JJ | denotes | anti-CD28 |
T571 | 134-136 | IN | denotes | in |
T572 | 137-142 | NN | denotes | vitro |
T573 | 143-145 | PRP | denotes | we |
T574 | 146-158 | VBD | denotes | demonstrated |
T575 | 159-163 | IN | denotes | that |
T576 | 164-175 | NN | denotes | fluticasone |
T577 | 176-184 | NNS | denotes | inhibits |
T578 | 185-192 | JJ | denotes | nuclear |
T579 | 193-206 | NN | denotes | translocation |
T580 | 207-209 | IN | denotes | of |
T581 | 210-216 | NNP | denotes | GATA-3 |
T582 | 217-220 | CC | denotes | and |
T583 | 221-231 | NN | denotes | expression |
T584 | 232-234 | IN | denotes | of |
T585 | 235-238 | JJ | denotes | Th2 |
T586 | 239-248 | NNS | denotes | cytokines |
T587 | 249-252 | IN | denotes | via |
T588 | 253-254 | DT | denotes | a |
T589 | 255-264 | NN | denotes | mechanism |
T590 | 265-276 | JJ | denotes | independent |
T591 | 277-279 | IN | denotes | of |
T592 | 280-287 | JJ | denotes | nuclear |
T593 | 288-297 | NN | denotes | factor-κB |
T594 | 298-301 | CC | denotes | and |
T595 | 302-304 | VBZ | denotes | is |
T596 | 305-308 | JJ | denotes | due |
T597 | 308-309 | , | denotes | , |
T598 | 310-312 | IN | denotes | in |
T599 | 313-317 | NN | denotes | part |
T600 | 317-318 | , | denotes | , |
T601 | 319-321 | TO | denotes | to |
T602 | 322-333 | NN | denotes | competition |
T603 | 334-341 | IN | denotes | between |
T604 | 342-348 | NNP | denotes | GATA-3 |
T605 | 349-352 | CC | denotes | and |
T606 | 353-356 | DT | denotes | the |
T607 | 357-373 | JJ | denotes | ligand-activated |
T608 | 374-388 | NN | denotes | glucocorticoid |
T609 | 389-397 | NN | denotes | receptor |
T610 | 398-401 | IN | denotes | for |
T611 | 402-409 | JJ | denotes | nuclear |
T612 | 410-419 | NN | denotes | transport |
T613 | 420-427 | IN | denotes | through |
T614 | 428-431 | DT | denotes | the |
T615 | 432-439 | JJ | denotes | nuclear |
T616 | 440-448 | NN | denotes | importer |
T617 | 449-459 | NN | denotes | importin-α |
T618 | 459-460 | . | denotes | . |
T619 | 461-463 | IN | denotes | In |
T620 | 464-472 | NN | denotes | addition |
T621 | 472-473 | , | denotes | , |
T622 | 474-485 | NN | denotes | fluticasone |
T623 | 486-493 | VBZ | denotes | induces |
T624 | 494-497 | DT | denotes | the |
T625 | 498-508 | NN | denotes | expression |
T626 | 509-511 | IN | denotes | of |
T627 | 512-529 | JJ | denotes | mitogen-activated |
T628 | 530-537 | NN | denotes | protein |
T629 | 538-544 | NN | denotes | kinase |
T630 | 545-546 | -LRB- | denotes | ( |
T631 | 546-550 | NNP | denotes | MAPK |
T632 | 550-551 | -RRB- | denotes | ) |
T633 | 552-565 | JJ | denotes | phosphatase-1 |
T634 | 566-567 | -LRB- | denotes | ( |
T635 | 567-572 | NNP | denotes | MKP-1 |
T636 | 572-573 | -RRB- | denotes | ) |
T637 | 573-574 | , | denotes | , |
T638 | 575-578 | DT | denotes | the |
T639 | 579-589 | JJ | denotes | endogenous |
T640 | 590-599 | NN | denotes | inhibitor |
T641 | 600-602 | IN | denotes | of |
T642 | 603-606 | CD | denotes | p38 |
T643 | 607-611 | NNP | denotes | MAPK |
T644 | 611-612 | , | denotes | , |
T645 | 613-618 | WDT | denotes | which |
T646 | 619-621 | VBZ | denotes | is |
T647 | 622-631 | JJ | denotes | necessary |
T648 | 632-635 | IN | denotes | for |
T649 | 636-642 | JJ | denotes | GATA-3 |
T650 | 643-650 | JJ | denotes | nuclear |
T651 | 651-664 | NN | denotes | translocation |
T652 | 664-665 | . | denotes | . |
T653 | 666-671 | DT | denotes | These |
T654 | 672-682 | JJ | denotes | inhibitory |
T655 | 683-690 | NNS | denotes | effects |
T656 | 691-693 | IN | denotes | of |
T657 | 694-705 | NN | denotes | fluticasone |
T658 | 706-709 | VBP | denotes | are |
T659 | 710-715 | JJ | denotes | rapid |
T660 | 715-716 | , | denotes | , |
T661 | 717-723 | JJ | denotes | potent |
T662 | 723-724 | , | denotes | , |
T663 | 725-728 | CC | denotes | and |
T664 | 729-738 | VBN | denotes | prolonged |
T665 | 738-739 | . | denotes | . |
T666 | 740-742 | PRP | denotes | We |
T667 | 743-747 | RB | denotes | also |
T668 | 748-760 | VBD | denotes | demonstrated |
T669 | 761-765 | IN | denotes | that |
T670 | 766-773 | JJ | denotes | inhaled |
T671 | 774-785 | NN | denotes | fluticasone |
T672 | 786-794 | VBZ | denotes | inhibits |
T673 | 795-801 | JJ | denotes | GATA-3 |
T674 | 802-809 | JJ | denotes | nuclear |
T675 | 810-823 | NN | denotes | translocation |
T676 | 824-826 | IN | denotes | in |
T677 | 827-837 | JJ | denotes | peripheral |
T678 | 838-843 | NN | denotes | blood |
T679 | 844-855 | NNS | denotes | lymphocytes |
T680 | 856-858 | IN | denotes | of |
T681 | 859-867 | NNS | denotes | patients |
T682 | 868-872 | IN | denotes | with |
T683 | 873-879 | NN | denotes | asthma |
T684 | 880-882 | IN | denotes | in |
T685 | 883-887 | NN | denotes | vivo |
T686 | 887-888 | . | denotes | . |
R398 | T590 | T589 | amod | independent,mechanism |
R400 | T591 | T590 | prep | of,independent |
R401 | T592 | T593 | amod | nuclear,factor-κB |
R403 | T593 | T591 | pobj | factor-κB,of |
R404 | T594 | T577 | cc | and,inhibits |
R405 | T595 | T577 | conj | is,inhibits |
R446 | T621 | T623 | punct | ",",induces |
R447 | T622 | T623 | nsubj | fluticasone,induces |
R449 | T623 | T623 | ROOT | induces,induces |
R450 | T624 | T625 | det | the,expression |
R451 | T625 | T623 | dobj | expression,induces |
R453 | T626 | T625 | prep | of,expression |
R454 | T627 | T629 | amod | mitogen-activated,kinase |
R455 | T628 | T629 | compound | protein,kinase |
R457 | T629 | T626 | pobj | kinase,of |
R458 | T630 | T631 | punct | (,MAPK |
R459 | T631 | T629 | appos | MAPK,kinase |
R460 | T632 | T629 | punct | ),kinase |
R461 | T633 | T625 | appos | phosphatase-1,expression |
R462 | T634 | T633 | punct | (,phosphatase-1 |
R464 | T635 | T633 | appos | MKP-1,phosphatase-1 |
R465 | T636 | T633 | punct | ),phosphatase-1 |
R466 | T637 | T633 | punct | ",",phosphatase-1 |
R468 | T638 | T640 | det | the,inhibitor |
R469 | T639 | T640 | amod | endogenous,inhibitor |
R470 | T640 | T633 | appos | inhibitor,phosphatase-1 |
R472 | T641 | T640 | prep | of,inhibitor |
R473 | T642 | T643 | nummod | p38,MAPK |
R475 | T643 | T641 | pobj | MAPK,of |
R476 | T644 | T643 | punct | ",",MAPK |
R477 | T645 | T646 | nsubj | which,is |
R478 | T646 | T643 | relcl | is,MAPK |
R480 | T647 | T646 | acomp | necessary,is |
R481 | T648 | T647 | prep | for,necessary |
R486 | T649 | T651 | amod | GATA-3,translocation |
R492 | T650 | T651 | amod | nuclear,translocation |
R499 | T651 | T648 | pobj | translocation,for |
R512 | T549 | T549 | ROOT | Methods,Methods |
R514 | T550 | T549 | cc | and,Methods |
R518 | T551 | T549 | conj | Findings,Methods |
R522 | T552 | T574 | prep | In,demonstrated |
R526 | T553 | T557 | det | a,line |
R529 | T554 | T557 | compound | T,line |
R534 | T555 | T557 | compound | lymphocyte,line |
R537 | T556 | T557 | compound | cell,line |
R541 | T557 | T552 | pobj | line,In |
R545 | T558 | T559 | punct | (,HuT-78 |
R548 | T559 | T565 | amod | HuT-78,cells |
R550 | T560 | T559 | punct | ),HuT-78 |
R551 | T561 | T559 | cc | and,HuT-78 |
R552 | T562 | T565 | amod | peripheral,cells |
R553 | T563 | T564 | compound | blood,mononuclear |
R556 | T564 | T565 | compound | mononuclear,cells |
R562 | T565 | T574 | nsubj | cells,demonstrated |
R565 | T566 | T565 | acl | stimulated,cells |
R569 | T567 | T566 | agent | by,stimulated |
R572 | T568 | T574 | advcl | anti-CD3,demonstrated |
R573 | T569 | T568 | cc | and,anti-CD3 |
R574 | T570 | T568 | conj | anti-CD28,anti-CD3 |
R575 | T571 | T574 | prep | in,demonstrated |
R577 | T572 | T571 | pobj | vitro,in |
R581 | T573 | T574 | nsubj | we,demonstrated |
R584 | T574 | T574 | ROOT | demonstrated,demonstrated |
R588 | T575 | T577 | mark | that,inhibits |
R592 | T576 | T577 | nsubj | fluticasone,inhibits |
R596 | T577 | T574 | ccomp | inhibits,demonstrated |
R600 | T578 | T579 | amod | nuclear,translocation |
R603 | T579 | T577 | dobj | translocation,inhibits |
R605 | T580 | T579 | prep | of,translocation |
R606 | T581 | T580 | pobj | GATA-3,of |
R607 | T582 | T579 | cc | and,translocation |
R608 | T583 | T579 | conj | expression,translocation |
R609 | T584 | T583 | prep | of,expression |
R610 | T585 | T586 | amod | Th2,cytokines |
R611 | T586 | T584 | pobj | cytokines,of |
R613 | T587 | T577 | prep | via,inhibits |
R616 | T588 | T589 | det | a,mechanism |
R619 | T589 | T587 | pobj | mechanism,via |
R434 | T611 | T612 | amod | nuclear,transport |
R435 | T612 | T610 | pobj | transport,for |
R437 | T613 | T610 | prep | through,for |
R438 | T614 | T616 | det | the,importer |
R439 | T615 | T616 | amod | nuclear,importer |
R440 | T616 | T613 | pobj | importer,through |
R441 | T617 | T609 | conj | importin-α,receptor |
R442 | T618 | T574 | punct | .,demonstrated |
R443 | T619 | T623 | prep | In,induces |
R445 | T620 | T619 | pobj | addition,In |
R505 | T652 | T623 | punct | .,induces |
R507 | T653 | T655 | det | These,effects |
R509 | T654 | T655 | amod | inhibitory,effects |
R510 | T655 | T658 | nsubj | effects,are |
R513 | T656 | T655 | prep | of,effects |
R515 | T657 | T656 | pobj | fluticasone,of |
R516 | T658 | T658 | ROOT | are,are |
R517 | T659 | T658 | acomp | rapid,are |
R519 | T660 | T659 | punct | ",",rapid |
R520 | T661 | T659 | conj | potent,rapid |
R521 | T662 | T658 | punct | ",",are |
R523 | T663 | T658 | cc | and,are |
R524 | T664 | T658 | conj | prolonged,are |
R525 | T665 | T658 | punct | .,are |
R527 | T666 | T668 | nsubj | We,demonstrated |
R528 | T667 | T668 | advmod | also,demonstrated |
R530 | T668 | T668 | ROOT | demonstrated,demonstrated |
R531 | T669 | T672 | mark | that,inhibits |
R532 | T670 | T671 | amod | inhaled,fluticasone |
R533 | T671 | T672 | nsubj | fluticasone,inhibits |
R535 | T672 | T668 | ccomp | inhibits,demonstrated |
R536 | T673 | T675 | amod | GATA-3,translocation |
R538 | T674 | T675 | amod | nuclear,translocation |
R539 | T675 | T672 | dobj | translocation,inhibits |
R540 | T676 | T675 | prep | in,translocation |
R542 | T677 | T679 | amod | peripheral,lymphocytes |
R543 | T678 | T679 | compound | blood,lymphocytes |
R544 | T679 | T676 | pobj | lymphocytes,in |
R546 | T680 | T679 | prep | of,lymphocytes |
R547 | T681 | T680 | pobj | patients,of |
R549 | T682 | T672 | prep | with,inhibits |
R554 | T683 | T682 | pobj | asthma,with |
R555 | T684 | T683 | prep | in,asthma |
R557 | T685 | T684 | pobj | vivo,in |
R558 | T686 | T668 | punct | .,demonstrated |
R414 | T596 | T595 | acomp | due,is |
R415 | T597 | T595 | punct | ",",is |
R416 | T598 | T595 | prep | in,is |
R418 | T599 | T598 | pobj | part,in |
R419 | T600 | T595 | punct | ",",is |
R421 | T601 | T577 | prep | to,inhibits |
R422 | T602 | T601 | pobj | competition,to |
R423 | T603 | T602 | prep | between,competition |
R425 | T604 | T603 | pobj | GATA-3,between |
R426 | T605 | T604 | cc | and,GATA-3 |
R428 | T606 | T609 | det | the,receptor |
R429 | T607 | T609 | amod | ligand-activated,receptor |
R430 | T608 | T609 | compound | glucocorticoid,receptor |
R432 | T609 | T604 | conj | receptor,GATA-3 |
R433 | T610 | T609 | prep | for,receptor |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T87 | 73-78 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T88 | 838-843 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T759 | 374-409 | http://purl.obolibrary.org/obo/GO_0002147 | denotes | glucocorticoid receptor for nuclear |
T760 | 402-419 | http://purl.obolibrary.org/obo/GO_0051169 | denotes | nuclear transport |
T761 | 410-419 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
T762 | 520-544 | http://purl.obolibrary.org/obo/GO_0034199 | denotes | activated protein kinase |
T763 | 520-544 | http://purl.obolibrary.org/obo/GO_0032147 | denotes | activated protein kinase |
T764 | 520-544 | http://purl.obolibrary.org/obo/GO_0030295 | denotes | activated protein kinase |
T765 | 520-544 | http://purl.obolibrary.org/obo/GO_0032111 | denotes | activated protein kinase |
T766 | 546-550 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
T767 | 603-606 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | p38 |
T768 | 552-563 | http://purl.obolibrary.org/obo/GO_0016791 | denotes | phosphatase |
T755 | 432-448 | http://purl.obolibrary.org/obo/GO_0051170 | denotes | nuclear importer |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T773 | 357-363 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | ligand |
T774 | 520-544 | http://purl.obolibrary.org/obo/GO_0030295 | denotes | activated protein kinase |
T775 | 546-550 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
T776 | 603-606 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | p38 |
T777 | 552-563 | http://purl.obolibrary.org/obo/GO_0016791 | denotes | phosphatase |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T779 | 91-96 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T140 | 0-20 | Sentence | denotes | Methods and Findings |
T141 | 21-460 | Sentence | denotes | In a T lymphocyte cell line (HuT-78) and peripheral blood mononuclear cells stimulated by anti-CD3 and anti-CD28 in vitro we demonstrated that fluticasone inhibits nuclear translocation of GATA-3 and expression of Th2 cytokines via a mechanism independent of nuclear factor-κB and is due, in part, to competition between GATA-3 and the ligand-activated glucocorticoid receptor for nuclear transport through the nuclear importer importin-α. |
T142 | 461-665 | Sentence | denotes | In addition, fluticasone induces the expression of mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1), the endogenous inhibitor of p38 MAPK, which is necessary for GATA-3 nuclear translocation. |
T143 | 666-739 | Sentence | denotes | These inhibitory effects of fluticasone are rapid, potent, and prolonged. |
T144 | 740-888 | Sentence | denotes | We also demonstrated that inhaled fluticasone inhibits GATA-3 nuclear translocation in peripheral blood lymphocytes of patients with asthma in vivo. |
T10 | 0-20 | Sentence | denotes | Methods and Findings |
T11 | 21-460 | Sentence | denotes | In a T lymphocyte cell line (HuT-78) and peripheral blood mononuclear cells stimulated by anti-CD3 and anti-CD28 in vitro we demonstrated that fluticasone inhibits nuclear translocation of GATA-3 and expression of Th2 cytokines via a mechanism independent of nuclear factor-κB and is due, in part, to competition between GATA-3 and the ligand-activated glucocorticoid receptor for nuclear transport through the nuclear importer importin-α. |
T12 | 461-665 | Sentence | denotes | In addition, fluticasone induces the expression of mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1), the endogenous inhibitor of p38 MAPK, which is necessary for GATA-3 nuclear translocation. |
T13 | 666-739 | Sentence | denotes | These inhibitory effects of fluticasone are rapid, potent, and prolonged. |
T14 | 740-888 | Sentence | denotes | We also demonstrated that inhaled fluticasone inhibits GATA-3 nuclear translocation in peripheral blood lymphocytes of patients with asthma in vivo. |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T780 | 873-879 | http://purl.bioontology.org/ontology/ICD10/J45 | denotes | asthma |
T769 | 873-879 | http://purl.bioontology.org/ontology/ICD10/J45.9 | denotes | asthma |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T893 | 176-184 | Negative_regulation | denotes | inhibits |
T894 | 185-192 | Entity | denotes | nuclear |
T895 | 193-206 | Localization | denotes | translocation |
T896 | 210-216 | Protein | denotes | GATA-3 |
T897 | 322-333 | Negative_regulation | denotes | competition |
T898 | 322-333 | Negative_regulation | denotes | competition |
T899 | 342-348 | Protein | denotes | GATA-3 |
T900 | 364-373 | Positive_regulation | denotes | activated |
T901 | 374-397 | Protein | denotes | glucocorticoid receptor |
T902 | 402-409 | Entity | denotes | nuclear |
T903 | 410-419 | Localization | denotes | transport |
T904 | 410-419 | Localization | denotes | transport |
T905 | 486-493 | Positive_regulation | denotes | induces |
T906 | 498-508 | Gene_expression | denotes | expression |
T907 | 512-565 | Protein | denotes | mitogen-activated protein kinase (MAPK) phosphatase-1 |
T908 | 567-572 | Protein | denotes | MKP-1 |
T909 | 622-631 | Positive_regulation | denotes | necessary |
T910 | 636-642 | Protein | denotes | GATA-3 |
T911 | 643-650 | Entity | denotes | nuclear |
T912 | 651-664 | Localization | denotes | translocation |
T913 | 786-794 | Negative_regulation | denotes | inhibits |
T914 | 795-801 | Protein | denotes | GATA-3 |
T915 | 802-809 | Entity | denotes | nuclear |
T916 | 810-823 | Localization | denotes | translocation |
R695 | T894 | T895 | locationOf | nuclear,translocation |
R696 | T895 | T893 | themeOf | translocation,inhibits |
R697 | T896 | T895 | themeOf | GATA-3,translocation |
R704 | T899 | T904 | themeOf | GATA-3,transport |
R707 | T901 | T903 | themeOf | glucocorticoid receptor,transport |
R708 | T901 | T900 | themeOf | glucocorticoid receptor,activated |
R709 | T902 | T904 | locationOf | nuclear,transport |
R710 | T902 | T903 | locationOf | nuclear,transport |
R712 | T903 | T897 | themeOf | transport,competition |
R714 | T904 | T898 | themeOf | transport,competition |
R715 | T906 | T905 | themeOf | expression,induces |
R716 | T907 | T906 | themeOf | mitogen-activated protein kinase (MAPK) phosphatase-1,expression |
R717 | T908 | T907 | equivalentTo | MKP-1,mitogen-activated protein kinase (MAPK) phosphatase-1 |
R718 | T910 | T912 | themeOf | GATA-3,translocation |
R720 | T911 | T912 | locationOf | nuclear,translocation |
R722 | T912 | T909 | themeOf | translocation,necessary |
R723 | T914 | T916 | themeOf | GATA-3,translocation |
R724 | T915 | T916 | locationOf | nuclear,translocation |
R725 | T916 | T913 | themeOf | translocation,inhibits |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T932 | 111-119 | Protein | denotes | anti-CD3 |
T933 | 124-133 | Protein | denotes | anti-CD28 |
T934 | 210-216 | Protein | denotes | GATA-3 |
T935 | 280-297 | Protein | denotes | nuclear factor-κB |
T936 | 342-348 | Protein | denotes | GATA-3 |
T937 | 374-397 | Protein | denotes | glucocorticoid receptor |
T938 | 185-192 | Entity | denotes | nuclear |
T939 | 193-206 | Localization | denotes | translocation |
T940 | 357-373 | Positive_regulation | denotes | ligand-activated |
T941 | 176-184 | Negative_regulation | denotes | inhibits |
T942 | 512-544 | Protein | denotes | mitogen-activated protein kinase |
T943 | 546-550 | Protein | denotes | MAPK |
T944 | 603-611 | Protein | denotes | p38 MAPK |
T945 | 498-508 | Gene_expression | denotes | expression |
T946 | 498-508 | Gene_expression | denotes | expression |
T947 | 590-599 | Negative_regulation | denotes | inhibitor |
T948 | 651-664 | Localization | denotes | translocation |
T949 | 486-493 | Positive_regulation | denotes | induces |
T950 | 486-493 | Positive_regulation | denotes | induces |
T951 | 622-631 | Positive_regulation | denotes | necessary |
R752 | T942 | T945 | themeOf | mitogen-activated protein kinase,expression |
R754 | T943 | T946 | themeOf | MAPK,expression |
R755 | T943 | T948 | themeOf | MAPK,translocation |
R756 | T944 | T947 | themeOf | p38 MAPK,inhibitor |
R758 | T945 | T949 | themeOf | expression,induces |
R759 | T946 | T950 | themeOf | expression,induces |
R761 | T948 | T951 | themeOf | translocation,necessary |
R746 | T934 | T939 | themeOf | GATA-3,translocation |
R747 | T937 | T940 | themeOf | glucocorticoid receptor,ligand-activated |
R748 | T938 | T939 | locationOf | nuclear,translocation |
R750 | T939 | T941 | themeOf | translocation,inhibits |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T109 | 176-184 | Negative_regulation | denotes | inhibits |
T110 | 185-192 | Entity | denotes | nuclear |
T111 | 193-206 | Localization | denotes | translocation |
T112 | 210-216 | Protein | denotes | GATA-3 |
T113 | 322-333 | Negative_regulation | denotes | competition |
T114 | 322-333 | Negative_regulation | denotes | competition |
T115 | 342-348 | Protein | denotes | GATA-3 |
T116 | 364-373 | Positive_regulation | denotes | activated |
T117 | 374-397 | Protein | denotes | glucocorticoid receptor |
T118 | 402-409 | Entity | denotes | nuclear |
T119 | 410-419 | Localization | denotes | transport |
T120 | 410-419 | Localization | denotes | transport |
T121 | 486-493 | Positive_regulation | denotes | induces |
T122 | 498-508 | Gene_expression | denotes | expression |
T123 | 512-565 | Protein | denotes | mitogen-activated protein kinase (MAPK) phosphatase-1 |
T124 | 567-572 | Protein | denotes | MKP-1 |
T125 | 622-631 | Positive_regulation | denotes | necessary |
T126 | 636-642 | Protein | denotes | GATA-3 |
T127 | 643-650 | Entity | denotes | nuclear |
T128 | 651-664 | Localization | denotes | translocation |
T129 | 786-794 | Negative_regulation | denotes | inhibits |
T130 | 795-801 | Protein | denotes | GATA-3 |
T131 | 802-809 | Entity | denotes | nuclear |
T132 | 810-823 | Localization | denotes | translocation |
R79 | T110 | T111 | locationOf | nuclear,translocation |
R80 | T111 | T109 | themeOf | translocation,inhibits |
R81 | T112 | T111 | themeOf | GATA-3,translocation |
R82 | T115 | T120 | themeOf | GATA-3,transport |
R83 | T117 | T119 | themeOf | glucocorticoid receptor,transport |
R84 | T117 | T116 | themeOf | glucocorticoid receptor,activated |
R85 | T118 | T120 | locationOf | nuclear,transport |
R86 | T118 | T119 | locationOf | nuclear,transport |
R87 | T119 | T113 | themeOf | transport,competition |
R88 | T120 | T114 | themeOf | transport,competition |
R89 | T122 | T121 | themeOf | expression,induces |
R90 | T123 | T122 | themeOf | mitogen-activated protein kinase (MAPK) phosphatase-1,expression |
R91 | T124 | T123 | equivalentTo | MKP-1,mitogen-activated protein kinase (MAPK) phosphatase-1 |
R92 | T126 | T128 | themeOf | GATA-3,translocation |
R93 | T127 | T128 | locationOf | nuclear,translocation |
R94 | T128 | T125 | themeOf | translocation,necessary |
R95 | T130 | T132 | themeOf | GATA-3,translocation |
R96 | T131 | T132 | locationOf | nuclear,translocation |
R97 | T132 | T129 | themeOf | translocation,inhibits |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T436 | 116-119 | P04234 | denotes | CD3 |
T437 | 116-119 | P20963 | denotes | CD3 |
T438 | 116-119 | P09693 | denotes | CD3 |
T439 | 116-119 | P07766 | denotes | CD3 |
T440 | 129-133 | P10747 | denotes | CD28 |
T441 | 210-216 | P23771 | denotes | GATA-3 |
T442 | 342-348 | P23771 | denotes | GATA-3 |
T443 | 374-397 | P04150 | denotes | glucocorticoid receptor |
T444 | 512-544 | P27361 | denotes | mitogen-activated protein kinase |
T445 | 512-544 | P28482 | denotes | mitogen-activated protein kinase |
T446 | 567-572 | P28562 | denotes | MKP-1 |
T447 | 603-606 | P53778 | denotes | p38 |
T448 | 603-606 | Q16539 | denotes | p38 |
T449 | 603-606 | Q15759 | denotes | p38 |
T450 | 603-606 | O15264 | denotes | p38 |
T451 | 636-642 | P23771 | denotes | GATA-3 |
T452 | 795-801 | P23771 | denotes | GATA-3 |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T63 | 176-184 | Negative_regulation | denotes | inhibits |
T64 | 185-192 | Entity | denotes | nuclear |
T65 | 193-206 | Localization | denotes | translocation |
T66 | 210-216 | Protein | denotes | GATA-3 |
T67 | 221-231 | Gene_expression | denotes | expression |
T68 | 265-276 | Regulation | denotes | independent |
T69 | 322-333 | Negative_regulation | denotes | competition |
T70 | 342-348 | Protein | denotes | GATA-3 |
T71 | 364-373 | Positive_regulation | denotes | activated |
T72 | 374-397 | Protein | denotes | glucocorticoid receptor |
T73 | 486-493 | Positive_regulation | denotes | induces |
T74 | 498-508 | Gene_expression | denotes | expression |
T75 | 512-565 | Protein | denotes | mitogen-activated protein kinase (MAPK) phosphatase-1 |
T76 | 567-572 | Protein | denotes | MKP-1 |
T77 | 622-631 | Positive_regulation | denotes | necessary |
T78 | 636-642 | Protein | denotes | GATA-3 |
T79 | 643-650 | Entity | denotes | nuclear |
T80 | 651-664 | Localization | denotes | translocation |
T81 | 786-794 | Negative_regulation | denotes | inhibits |
T82 | 795-801 | Protein | denotes | GATA-3 |
T83 | 802-809 | Entity | denotes | nuclear |
T84 | 810-823 | Localization | denotes | translocation |
R59 | T72 | T71 | themeOf | glucocorticoid receptor,activated |
R60 | T74 | T73 | themeOf | expression,induces |
R61 | T74 | T77 | causeOf | expression,necessary |
R62 | T75 | T74 | themeOf | mitogen-activated protein kinase (MAPK) phosphatase-1,expression |
R63 | T76 | T75 | equivalentTo | MKP-1,mitogen-activated protein kinase (MAPK) phosphatase-1 |
R64 | T78 | T80 | themeOf | GATA-3,translocation |
R65 | T79 | T80 | locationOf | nuclear,translocation |
R66 | T80 | T77 | themeOf | translocation,necessary |
R67 | T82 | T84 | themeOf | GATA-3,translocation |
R68 | T83 | T84 | locationOf | nuclear,translocation |
R69 | T84 | T81 | themeOf | translocation,inhibits |
R50 | T63 | T68 | themeOf | inhibits,independent |
R51 | T64 | T65 | locationOf | nuclear,translocation |
R52 | T65 | T68 | themeOf | translocation,independent |
R53 | T65 | T63 | themeOf | translocation,inhibits |
R54 | T66 | T67 | themeOf | GATA-3,expression |
R55 | T67 | T63 | themeOf | expression,inhibits |
R56 | T67 | T68 | themeOf | expression,independent |
R57 | T70 | T71 | themeOf | GATA-3,activated |
R58 | T70 | T69 | themeOf | GATA-3,competition |