PMC:2626671 / 1697-2107
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1593 | 3-18 | NN | denotes | differentiation |
T1594 | 19-20 | -LRB- | denotes | ( |
T1595 | 20-24 | NN | denotes | 5, 6 |
T1596 | 24-25 | -RRB- | denotes | ) |
T1597 | 25-30 | NN | denotes | . The |
T1598 | 31-36 | NN | denotes | T-box |
T1599 | 37-50 | NN | denotes | transcription |
T1600 | 51-58 | NN | denotes | factors |
T1601 | 59-71 | NN | denotes | Eomesodermin |
T1602 | 72-73 | -LRB- | denotes | ( |
T1603 | 73-78 | NN | denotes | Eomes |
T1604 | 78-79 | -RRB- | denotes | ) |
T1605 | 80-83 | CC | denotes | and |
T1606 | 84-89 | NN | denotes | T-bet |
T1607 | 90-93 | VB | denotes | are |
T1608 | 94-100 | VB | denotes | needed |
T1609 | 101-104 | IN | denotes | for |
T1610 | 105-114 | JJ | denotes | important |
T1611 | 115-122 | NN | denotes | aspects |
T1612 | 123-125 | IN | denotes | of |
T1613 | 126-134 | NN | denotes | effector |
T1614 | 135-138 | CC | denotes | and |
T1615 | 139-145 | NN | denotes | memory |
T1616 | 146-149 | NN | denotes | CTL |
T1617 | 150-165 | NN | denotes | differentiation |
T1618 | 166-167 | -LRB- | denotes | ( |
T1619 | 167-168 | CD | denotes | 7 |
T1620 | 168-169 | -RRB- | denotes | ) |
T1621 | 171-173 | IN | denotes | In |
T1622 | 174-184 | JJ | denotes | uninfected |
T1623 | 185-189 | NN | denotes | mice |
T1624 | 189-190 | -COMMA- | denotes | , |
T1625 | 191-199 | NN | denotes | compound |
T1626 | 200-208 | NN | denotes | deletion |
T1627 | 209-211 | IN | denotes | of |
T1628 | 212-221 | NN | denotes | the Tbx21 |
T1629 | 222-223 | -LRB- | denotes | ( |
T1630 | 223-231 | VB | denotes | encoding |
T1631 | 232-237 | NN | denotes | T-bet |
T1632 | 237-238 | -RRB- | denotes | ) |
T1633 | 239-261 | NN | denotes | and eomesodermin genes |
T1634 | 262-264 | VB | denotes | is |
T1635 | 265-275 | VB | denotes | associated |
T1636 | 276-280 | IN | denotes | with |
T1637 | 281-282 | DT | denotes | a |
T1638 | 283-292 | JJ | denotes | selective |
T1639 | 293-297 | NN | denotes | loss |
T1640 | 298-300 | IN | denotes | of |
T1641 | 301-307 | NN | denotes | CD8+ T |
T1642 | 308-313 | NN | denotes | cells |
T1643 | 314-318 | IN | denotes | with |
T1644 | 319-321 | DT | denotes | an |
T1645 | 322-333 | NN | denotes | IL-2Rβ–high |
T1646 | 333-334 | -COMMA- | denotes | , |
T1647 | 335-341 | NN | denotes | memory |
T1648 | 342-351 | NN | denotes | phenotype |
T1649 | 352-353 | -LRB- | denotes | ( |
T1650 | 353-354 | CD | denotes | 8 |
T1651 | 354-355 | -RRB- | denotes | ) |
T1652 | 357-361 | NN | denotes | Mice |
T1653 | 362-371 | JJ | denotes | deficient |
T1654 | 372-375 | IN | denotes | for |
T1655 | 376-380 | CC | denotes | both |
T1656 | 381-386 | NN | denotes | T-bet |
T1657 | 387-390 | CC | denotes | and |
T1658 | 391-396 | NN | denotes | Eomes |
T1659 | 397-399 | IN | denotes | in |
T1660 | 400-401 | NN | denotes | T |
T1661 | 402-407 | NN | denotes | cells |
R1320 | T1593 | T1594 | arg1Of | differentiation,( |
R1321 | T1595 | T1594 | arg2Of | "5, 6",( |
R1322 | T1596 | T1594 | arg3Of | ),( |
R1324 | T1604 | T1602 | arg3Of | ),( |
R1325 | T1601 | T1593 | arg1Of | Eomesodermin,differentiation |
R1326 | T1601 | T1597 | arg1Of | Eomesodermin,". The" |
R1327 | T1601 | T1598 | arg1Of | Eomesodermin,T-box |
R1330 | T1601 | T1599 | arg1Of | Eomesodermin,transcription |
R1331 | T1601 | T1600 | arg1Of | Eomesodermin,factors |
R1332 | T1606 | T1607 | arg1Of | T-bet,are |
R1333 | T1606 | T1608 | arg2Of | T-bet,needed |
R1334 | T1601 | T1602 | arg1Of | Eomesodermin,( |
R1335 | T1603 | T1602 | arg2Of | Eomes,( |
R1336 | T1608 | T1605 | arg2Of | needed,and |
R1337 | T1608 | T1607 | arg2Of | needed,are |
R1338 | T1608 | T1609 | arg1Of | needed,for |
R1339 | T1611 | T1610 | arg1Of | aspects,important |
R1340 | T1611 | T1612 | arg1Of | aspects,of |
R1341 | T1611 | T1614 | arg1Of | aspects,and |
R1342 | T1613 | T1612 | arg2Of | effector,of |
R1344 | T1614 | T1609 | arg2Of | and,for |
R1345 | T1617 | T1614 | arg2Of | differentiation,and |
R1346 | T1617 | T1615 | arg1Of | differentiation,memory |
R1347 | T1617 | T1616 | arg1Of | differentiation,CTL |
R1348 | T1617 | T1618 | arg1Of | differentiation,( |
R1349 | T1619 | T1618 | arg2Of | 7,( |
R1350 | T1620 | T1618 | arg3Of | ),( |
R1351 | T1623 | T1621 | arg2Of | mice,In |
R1352 | T1623 | T1622 | arg1Of | mice,uninfected |
R1355 | T1626 | T1625 | arg1Of | deletion,compound |
R1356 | T1626 | T1627 | arg1Of | deletion,of |
R1357 | T1626 | T1634 | arg1Of | deletion,is |
R1358 | T1626 | T1635 | arg2Of | deletion,associated |
R1363 | T1631 | T1629 | arg2Of | T-bet,( |
R1364 | T1631 | T1630 | arg1Of | T-bet,encoding |
R1365 | T1632 | T1629 | arg3Of | ),( |
R1367 | T1633 | T1627 | arg2Of | and eomesodermin genes,of |
R1368 | T1633 | T1628 | arg1Of | and eomesodermin genes,the Tbx21 |
R1369 | T1633 | T1629 | arg1Of | and eomesodermin genes,( |
R1371 | T1635 | T1621 | arg1Of | associated,In |
R1372 | T1635 | T1624 | arg1Of | associated,"," |
R1373 | T1635 | T1634 | arg2Of | associated,is |
R1374 | T1635 | T1636 | arg1Of | associated,with |
R1375 | T1639 | T1636 | arg2Of | loss,with |
R1378 | T1639 | T1637 | arg1Of | loss,a |
R1379 | T1639 | T1638 | arg1Of | loss,selective |
R1380 | T1639 | T1640 | arg1Of | loss,of |
R1381 | T1639 | T1643 | arg1Of | loss,with |
R1382 | T1642 | T1640 | arg2Of | cells,of |
R1383 | T1642 | T1641 | arg1Of | cells,CD8+ T |
R1386 | T1645 | T1643 | arg2Of | IL-2Rβ–high,with |
R1387 | T1645 | T1644 | arg1Of | IL-2Rβ–high,an |
R1388 | T1645 | T1646 | arg1Of | IL-2Rβ–high,"," |
R1392 | T1648 | T1646 | arg2Of | phenotype,"," |
R1393 | T1648 | T1647 | arg1Of | phenotype,memory |
R1394 | T1648 | T1649 | arg1Of | phenotype,( |
R1395 | T1650 | T1649 | arg2Of | 8,( |
R1396 | T1651 | T1649 | arg3Of | ),( |
R1397 | T1652 | T1653 | arg1Of | Mice,deficient |
R1403 | T1653 | T1654 | arg1Of | deficient,for |
R1404 | T1656 | T1657 | arg1Of | T-bet,and |
R1405 | T1657 | T1654 | arg2Of | and,for |
R1406 | T1657 | T1655 | arg1Of | and,both |
R1407 | T1657 | T1659 | arg1Of | and,in |
R1408 | T1658 | T1657 | arg2Of | Eomes,and |
R1411 | T1661 | T1659 | arg2Of | cells,in |
R1412 | T1661 | T1660 | arg1Of | cells,T |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T974 | 3-18 | NN | denotes | differentiation |
T975 | 19-20 | -LRB- | denotes | ( |
T976 | 20-24 | CD | denotes | 5, 6 |
T977 | 24-25 | -RRB- | denotes | ) |
T978 | 25-26 | . | denotes | . |
T979 | 27-30 | DT | denotes | The |
T980 | 31-36 | NN | denotes | T-box |
T981 | 37-50 | NN | denotes | transcription |
T982 | 51-58 | NNS | denotes | factors |
T983 | 59-71 | NNP | denotes | Eomesodermin |
T984 | 72-73 | -LRB- | denotes | ( |
T985 | 73-78 | NNP | denotes | Eomes |
T986 | 78-79 | -RRB- | denotes | ) |
T987 | 80-83 | CC | denotes | and |
T988 | 84-89 | NNP | denotes | T-bet |
T989 | 90-93 | VBP | denotes | are |
T990 | 94-100 | VBN | denotes | needed |
T991 | 101-104 | IN | denotes | for |
T992 | 105-114 | JJ | denotes | important |
T993 | 115-122 | NNS | denotes | aspects |
T994 | 123-125 | IN | denotes | of |
T995 | 126-134 | NN | denotes | effector |
T996 | 135-138 | CC | denotes | and |
T997 | 139-145 | NN | denotes | memory |
T998 | 146-149 | NNP | denotes | CTL |
T999 | 150-165 | NN | denotes | differentiation |
T1000 | 166-167 | -LRB- | denotes | ( |
T1001 | 167-168 | CD | denotes | 7 |
T1002 | 168-169 | -RRB- | denotes | ) |
T1003 | 169-170 | . | denotes | . |
T1004 | 171-173 | IN | denotes | In |
T1005 | 174-184 | JJ | denotes | uninfected |
T1006 | 185-189 | NNS | denotes | mice |
T1007 | 189-190 | , | denotes | , |
T1008 | 191-199 | NN | denotes | compound |
T1009 | 200-208 | NN | denotes | deletion |
T1010 | 209-211 | IN | denotes | of |
T1011 | 212-221 | NNP | denotes | the Tbx21 |
T1012 | 222-223 | -LRB- | denotes | ( |
T1013 | 223-231 | VBG | denotes | encoding |
T1014 | 232-237 | NNP | denotes | T-bet |
T1015 | 237-238 | -RRB- | denotes | ) |
T1016 | 239-261 | NNS | denotes | and eomesodermin genes |
T1017 | 262-264 | VBZ | denotes | is |
T1018 | 265-275 | VBN | denotes | associated |
T1019 | 276-280 | IN | denotes | with |
T1020 | 281-282 | DT | denotes | a |
T1021 | 283-292 | JJ | denotes | selective |
T1022 | 293-297 | NN | denotes | loss |
T1023 | 298-300 | IN | denotes | of |
T1024 | 301-304 | CD | denotes | CD8 |
T1025 | 304-305 | CD | denotes | + |
T1026 | 306-307 | NNP | denotes | T |
T1027 | 308-313 | NNS | denotes | cells |
T1028 | 314-318 | IN | denotes | with |
T1029 | 319-321 | DT | denotes | an |
T1030 | 322-328 | NN | denotes | IL-2Rβ |
T1031 | 329-333 | JJ | denotes | high |
T1032 | 333-334 | , | denotes | , |
T1033 | 335-341 | NN | denotes | memory |
T1034 | 342-351 | NN | denotes | phenotype |
T1035 | 352-353 | -LRB- | denotes | ( |
T1036 | 353-354 | CD | denotes | 8 |
T1037 | 354-355 | -RRB- | denotes | ) |
T1038 | 355-356 | . | denotes | . |
T1039 | 357-361 | NNP | denotes | Mice |
T1040 | 362-371 | NN | denotes | deficient |
T1041 | 372-375 | IN | denotes | for |
T1042 | 376-380 | DT | denotes | both |
T1043 | 381-386 | NNP | denotes | T-bet |
T1044 | 387-390 | CC | denotes | and |
T1045 | 391-396 | NNP | denotes | Eomes |
T1046 | 397-399 | IN | denotes | in |
T1047 | 400-401 | NNP | denotes | T |
T1048 | 402-407 | NNS | denotes | cells |
R741 | T975 | T974 | punct | (,differentiation |
R742 | T976 | T974 | appos | "5, 6",differentiation |
R743 | T977 | T974 | punct | ),differentiation |
R745 | T979 | T982 | det | The,factors |
R746 | T980 | T982 | amod | T-box,factors |
R747 | T981 | T982 | compound | transcription,factors |
R748 | T982 | T990 | nsubjpass | factors,needed |
R749 | T983 | T990 | nsubjpass | Eomesodermin,needed |
R750 | T984 | T985 | punct | (,Eomes |
R751 | T985 | T983 | appos | Eomes,Eomesodermin |
R752 | T986 | T985 | punct | ),Eomes |
R753 | T987 | T983 | cc | and,Eomesodermin |
R754 | T988 | T983 | conj | T-bet,Eomesodermin |
R755 | T989 | T990 | auxpass | are,needed |
R756 | T990 | T990 | ROOT | needed,needed |
R757 | T991 | T990 | prep | for,needed |
R758 | T992 | T993 | amod | important,aspects |
R759 | T993 | T991 | pobj | aspects,for |
R760 | T994 | T993 | prep | of,aspects |
R761 | T995 | T994 | pobj | effector,of |
R762 | T996 | T995 | cc | and,effector |
R763 | T997 | T999 | compound | memory,differentiation |
R764 | T998 | T999 | compound | CTL,differentiation |
R765 | T999 | T995 | conj | differentiation,effector |
R766 | T1000 | T1001 | punct | (,7 |
R767 | T1001 | T999 | npadvmod | 7,differentiation |
R768 | T1002 | T990 | punct | ),needed |
R769 | T1003 | T990 | punct | .,needed |
R770 | T1004 | T1018 | prep | In,associated |
R771 | T1005 | T1006 | amod | uninfected,mice |
R772 | T1006 | T1004 | pobj | mice,In |
R773 | T1007 | T1018 | punct | ",",associated |
R774 | T1008 | T1009 | compound | compound,deletion |
R775 | T1009 | T1018 | nsubjpass | deletion,associated |
R776 | T1010 | T1009 | prep | of,deletion |
R777 | T1011 | T1010 | pobj | the Tbx21,of |
R778 | T1012 | T1013 | punct | (,encoding |
R779 | T1013 | T1016 | nmod | encoding,and eomesodermin genes |
R780 | T1014 | T1013 | dobj | T-bet,encoding |
R781 | T1015 | T1016 | punct | ),and eomesodermin genes |
R782 | T1016 | T1009 | nmod | and eomesodermin genes,deletion |
R783 | T1017 | T1018 | auxpass | is,associated |
R784 | T1018 | T1018 | ROOT | associated,associated |
R785 | T1019 | T1018 | prep | with,associated |
R786 | T1020 | T1022 | det | a,loss |
R787 | T1021 | T1022 | amod | selective,loss |
R788 | T1022 | T1019 | pobj | loss,with |
R789 | T1023 | T1022 | prep | of,loss |
R790 | T1024 | T1027 | nummod | CD8,cells |
R791 | T1025 | T1027 | nummod | +,cells |
R792 | T1026 | T1027 | compound | T,cells |
R793 | T1027 | T1023 | pobj | cells,of |
R794 | T1028 | T1022 | prep | with,loss |
R795 | T1029 | T1030 | det | an,IL-2Rβ |
R796 | T1030 | T1028 | pobj | IL-2Rβ,with |
R797 | T1031 | T1030 | amod | high,IL-2Rβ |
R798 | T1032 | T1031 | punct | ",",high |
R799 | T1033 | T1034 | compound | memory,phenotype |
R800 | T1034 | T1030 | appos | phenotype,IL-2Rβ |
R801 | T1035 | T1036 | punct | (,8 |
R802 | T1036 | T1034 | parataxis | 8,phenotype |
R803 | T1037 | T1036 | punct | ),8 |
R804 | T1038 | T1018 | punct | .,associated |
R805 | T1039 | T1040 | npadvmod | Mice,deficient |
R807 | T1041 | T1040 | prep | for,deficient |
R808 | T1042 | T1043 | det | both,T-bet |
R809 | T1043 | T1041 | pobj | T-bet,for |
R810 | T1044 | T1043 | cc | and,T-bet |
R811 | T1045 | T1043 | conj | Eomes,T-bet |
R812 | T1046 | T1040 | prep | in,deficient |
R813 | T1047 | T1048 | compound | T,cells |
R814 | T1048 | T1046 | pobj | cells,in |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T872 | 37-50 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T876 | 139-145 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
T877 | 335-341 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2081 | 308-313 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T2082 | 402-407 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T831 | 171-356 | Sentence | denotes | In uninfected mice, compound deletion of the Tbx21 (encoding T-bet) and eomesodermin genes is associated with a selective loss of CD8+ T cells with an IL-2Rβ–high, memory phenotype (8). |
T12 | 27-170 | Sentence | denotes | The T-box transcription factors Eomesodermin (Eomes) and T-bet are needed for important aspects of effector and memory CTL differentiation (7). |
T13 | 171-356 | Sentence | denotes | In uninfected mice, compound deletion of the Tbx21 (encoding T-bet) and eomesodermin genes is associated with a selective loss of CD8+ T cells with an IL-2Rβ–high, memory phenotype (8). |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2564 | 59-71 | Protein | denotes | Eomesodermin |
T2565 | 73-78 | Protein | denotes | Eomes |
T2566 | 84-89 | Protein | denotes | T-bet |
T2567 | 200-208 | Negative_regulation | denotes | deletion |
T2568 | 200-208 | Negative_regulation | denotes | deletion |
T2569 | 216-221 | Protein | denotes | Tbx21 |
T2570 | 232-237 | Protein | denotes | T-bet |
T2571 | 243-255 | Protein | denotes | eomesodermin |
T2572 | 301-304 | Protein | denotes | CD8 |
T2573 | 322-328 | Protein | denotes | IL-2Rβ |
T2574 | 362-371 | Negative_regulation | denotes | deficient |
T2575 | 362-371 | Negative_regulation | denotes | deficient |
T2576 | 381-386 | Protein | denotes | T-bet |
T2577 | 391-396 | Protein | denotes | Eomes |
R2003 | T2565 | T2564 | equivalentTo | Eomes,Eomesodermin |
R2007 | T2569 | T2567 | themeOf | Tbx21,deletion |
R2008 | T2570 | T2569 | equivalentTo | T-bet,Tbx21 |
R2009 | T2571 | T2568 | themeOf | eomesodermin,deletion |
R2011 | T2576 | T2574 | themeOf | T-bet,deficient |
R2012 | T2577 | T2575 | themeOf | Eomes,deficient |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1425 | 200-208 | Negative_regulation | denotes | deletion |
T1436 | 200-208 | Negative_regulation | denotes | deletion |
T1440 | 362-371 | Negative_regulation | denotes | deficient |
T1441 | 362-371 | Negative_regulation | denotes | deficient |
T1446 | 232-237 | Protein | denotes | T-bet |
T1447 | 243-255 | Protein | denotes | eomesodermin |
T1448 | 301-304 | Protein | denotes | CD8 |
T1449 | 381-386 | Protein | denotes | T-bet |
T1450 | 391-396 | Protein | denotes | Eomes |
T1497 | 59-71 | Protein | denotes | Eomesodermin |
T1498 | 73-78 | Protein | denotes | Eomes |
T1499 | 84-89 | Protein | denotes | T-bet |
T1501 | 216-221 | Protein | denotes | Tbx21 |
T1502 | 322-328 | Protein | denotes | IL-2Rβ |
R1229 | T1501 | T1425 | themeOf | Tbx21,deletion |
R1183 | T1447 | T1436 | themeOf | eomesodermin,deletion |
R1184 | T1449 | T1440 | themeOf | T-bet,deficient |
R1185 | T1450 | T1441 | themeOf | Eomes,deficient |
R1182 | T1446 | T1501 | equivalentTo | T-bet,Tbx21 |
R1224 | T1498 | T1497 | equivalentTo | Eomes,Eomesodermin |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2006 | 73-78 | O95936 | denotes | Eomes |
T2007 | 84-89 | Q9UL17 | denotes | T-bet |
T2008 | 232-237 | Q9UL17 | denotes | T-bet |
T2009 | 301-304 | P10966 | denotes | CD8 |
T2010 | 301-304 | P01732 | denotes | CD8 |
T2011 | 381-386 | Q9UL17 | denotes | T-bet |
T2012 | 391-396 | O95936 | denotes | Eomes |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T761 | 391-396 | Protein | denotes | Eomes | |
T749 | 59-71 | Protein | denotes | Eomesodermin | |
T750 | 73-78 | Protein | denotes | Eomes | |
T751 | 84-89 | Protein | denotes | T-bet | true |
T752 | 200-208 | Negative_regulation | denotes | deletion | true |
T753 | 212-221 | Protein | denotes | the Tbx21 | true |
T754 | 232-237 | Protein | denotes | T-bet | |
T755 | 239-261 | Protein | denotes | and eomesodermin genes | |
T756 | 265-275 | Binding | denotes | associated | |
T757 | 301-304 | Protein | denotes | CD8 | |
T758 | 322-328 | Protein | denotes | IL-2Rβ | |
T759 | 362-371 | Negative_regulation | denotes | deficient | |
T760 | 381-386 | Protein | denotes | T-bet | |
R595 | T750 | T749 | equivalentTo | Eomes,Eomesodermin | |
R596 | T753 | T752 | themeOf | the Tbx21,deletion | |
R597 | T754 | T753 | equivalentTo | T-bet,the Tbx21 | |
R598 | T755 | T756 | themeOf | and eomesodermin genes,associated | |
R599 | T755 | T752 | themeOf | and eomesodermin genes,deletion | |
R600 | T760 | T759 | themeOf | T-bet,deficient | |
R601 | T761 | T759 | themeOf | Eomes,deficient |