PMC:1858683 / 29489-29959 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T27661","span":{"begin":50,"end":53},"obj":"DT"},{"id":"T27660","span":{"begin":47,"end":49},"obj":"IN"},{"id":"T27659","span":{"begin":39,"end":46},"obj":"NNS"},{"id":"T27658","span":{"begin":28,"end":38},"obj":"NN"},{"id":"T27657","span":{"begin":23,"end":27},"obj":"NN"},{"id":"T27656","span":{"begin":20,"end":22},"obj":"IN"},{"id":"T27655","span":{"begin":9,"end":19},"obj":"NN"},{"id":"T27675","span":{"begin":122,"end":123},"obj":"."},{"id":"T27674","span":{"begin":109,"end":110},"obj":"HYPH"},{"id":"T27673","span":{"begin":110,"end":114},"obj":"NN"},{"id":"T27672","span":{"begin":105,"end":109},"obj":"JJ"},{"id":"T27671","span":{"begin":115,"end":122},"obj":"NNS"},{"id":"T27670","span":{"begin":99,"end":104},"obj":"NN"},{"id":"T27669","span":{"begin":96,"end":98},"obj":"IN"},{"id":"T27668","span":{"begin":85,"end":95},"obj":"VBN"},{"id":"T27667","span":{"begin":72,"end":76},"obj":"JJ"},{"id":"T27666","span":{"begin":65,"end":66},"obj":"HYPH"},{"id":"T27665","span":{"begin":66,"end":71},"obj":"NN"},{"id":"T27664","span":{"begin":60,"end":65},"obj":"NN"},{"id":"T27663","span":{"begin":54,"end":59},"obj":"NN"},{"id":"T27662","span":{"begin":77,"end":84},"obj":"NNS"}],"relations":[{"id":"R8046","pred":"prep","subj":"T27656","obj":"T27655"},{"id":"R8047","pred":"compound","subj":"T27657","obj":"T27658"},{"id":"R8048","pred":"compound","subj":"T27658","obj":"T27659"},{"id":"R8049","pred":"pobj","subj":"T27659","obj":"T27656"},{"id":"R8050","pred":"prep","subj":"T27660","obj":"T27659"},{"id":"R8051","pred":"det","subj":"T27661","obj":"T27662"},{"id":"R8052","pred":"pobj","subj":"T27662","obj":"T27660"},{"id":"R8053","pred":"nmod","subj":"T27663","obj":"T27662"},{"id":"R8054","pred":"compound","subj":"T27664","obj":"T27665"},{"id":"R8055","pred":"npadvmod","subj":"T27665","obj":"T27667"},{"id":"R8056","pred":"punct","subj":"T27666","obj":"T27665"},{"id":"R8057","pred":"amod","subj":"T27667","obj":"T27662"},{"id":"R8058","pred":"acl","subj":"T27668","obj":"T27659"},{"id":"R8059","pred":"prep","subj":"T27669","obj":"T27668"},{"id":"R8060","pred":"nmod","subj":"T27670","obj":"T27671"},{"id":"R8061","pred":"pobj","subj":"T27671","obj":"T27669"},{"id":"R8062","pred":"amod","subj":"T27672","obj":"T27673"},{"id":"R8063","pred":"compound","subj":"T27673","obj":"T27671"},{"id":"R8064","pred":"punct","subj":"T27674","obj":"T27673"},{"id":"R8065","pred":"punct","subj":"T27675","obj":"T27655"}],"text":"Table 4 Validation of gene expression changes in the E18.5 Pygo1/Pygo2 null kidneys normalized to E18.5 wild-type kidneys.\nGene symbol Microarray fold change QPCR fold change (SD) Validation\nAldh1a7 - 2.2 1.1 (0.11) No\nCol8a1 2.1 2.9 (0.78) Yes\nCsrp1 - 7.1 1.2 (0.02) No\nKlk5 2.8 5.8 (0.74) Yes\nPygo2 - 3.9 - 3.7 (0.04) Yes\nPicalm 3.1 2.2 (0.24) Yes\nRen2 2.2 6.1 (0.36) Yes\nTia1 6.6 and 2.3 Amplification not detected in wild-type samples Yes"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T27654","span":{"begin":115,"end":122},"obj":"UBERON:0002113"},{"id":"T27653","span":{"begin":105,"end":114},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T27652","span":{"begin":77,"end":84},"obj":"UBERON:0002113"},{"id":"T27651","span":{"begin":72,"end":76},"obj":"SO_EXT:sequence_nullness"},{"id":"T27650","span":{"begin":66,"end":71},"obj":"PR_EXT:000013524"},{"id":"T27649","span":{"begin":60,"end":65},"obj":"PR_EXT:000013523"},{"id":"T27648","span":{"begin":23,"end":38},"obj":"GO:0010467"},{"id":"T27647","span":{"begin":23,"end":27},"obj":"SO_EXT:0000704"}],"text":"Table 4 Validation of gene expression changes in the E18.5 Pygo1/Pygo2 null kidneys normalized to E18.5 wild-type kidneys.\nGene symbol Microarray fold change QPCR fold change (SD) Validation\nAldh1a7 - 2.2 1.1 (0.11) No\nCol8a1 2.1 2.9 (0.78) Yes\nCsrp1 - 7.1 1.2 (0.02) No\nKlk5 2.8 5.8 (0.74) Yes\nPygo2 - 3.9 - 3.7 (0.04) Yes\nPicalm 3.1 2.2 (0.24) Yes\nRen2 2.2 6.1 (0.36) Yes\nTia1 6.6 and 2.3 Amplification not detected in wild-type samples Yes"}

{"project":"craft-ca-core-dev","denotations":[{"id":"T27646","span":{"begin":115,"end":122},"obj":"UBERON:0002113"},{"id":"T27645","span":{"begin":77,"end":84},"obj":"UBERON:0002113"},{"id":"T27644","span":{"begin":66,"end":71},"obj":"PR:000013524"},{"id":"T27643","span":{"begin":60,"end":65},"obj":"PR:000013523"},{"id":"T27642","span":{"begin":23,"end":38},"obj":"GO:0010467"},{"id":"T27641","span":{"begin":23,"end":27},"obj":"SO:0000704"}],"text":"Table 4 Validation of gene expression changes in the E18.5 Pygo1/Pygo2 null kidneys normalized to E18.5 wild-type kidneys.\nGene symbol Microarray fold change QPCR fold change (SD) Validation\nAldh1a7 - 2.2 1.1 (0.11) No\nCol8a1 2.1 2.9 (0.78) Yes\nCsrp1 - 7.1 1.2 (0.02) No\nKlk5 2.8 5.8 (0.74) Yes\nPygo2 - 3.9 - 3.7 (0.04) Yes\nPicalm 3.1 2.2 (0.24) Yes\nRen2 2.2 6.1 (0.36) Yes\nTia1 6.6 and 2.3 Amplification not detected in wild-type samples Yes"}