PMC:1584416 / 570-946 JSONTXT

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    craft-sa-dev

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pleiotropy associated with XPD recessive disorders in compound heterozygous mouse models. 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    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T28","span":{"begin":34,"end":37},"obj":"PR:000007164"},{"id":"T29","span":{"begin":83,"end":88},"obj":"NCBITaxon:10088"},{"id":"T30","span":{"begin":160,"end":170},"obj":"GO:0006281"},{"id":"T31","span":{"begin":349,"end":356},"obj":"SO:0001023"}],"text":"gmatic pleiotropy associated with XPD recessive disorders in compound heterozygous mouse models. Alterations in this essential helicase, with functions in both DNA repair and basal transcription, result in diverse pathologies ranging from elevated UV sensitivity and cancer predisposition to accelerated segmental progeria. We report a variety of biallelic effects on organism"}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T58","span":{"begin":34,"end":37},"obj":"PR_EXT:000007164"},{"id":"T59","span":{"begin":83,"end":88},"obj":"NCBITaxon:10088"},{"id":"T60","span":{"begin":97,"end":108},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T61","span":{"begin":127,"end":135},"obj":"GO_EXT:0004386"},{"id":"T62","span":{"begin":160,"end":163},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T63","span":{"begin":160,"end":170},"obj":"GO:0006281"},{"id":"T64","span":{"begin":181,"end":194},"obj":"GO_EXT:transcription"},{"id":"T65","span":{"begin":349,"end":356},"obj":"SO_EXT:0001023"}],"text":"gmatic pleiotropy associated with XPD recessive disorders in compound heterozygous mouse models. Alterations in this essential helicase, with functions in both DNA repair and basal transcription, result in diverse pathologies ranging from elevated UV sensitivity and cancer predisposition to accelerated segmental progeria. We report a variety of biallelic effects on organism"}