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PMC:1064895 / 28101-28796 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T22090 574-579 Protein denotes IL-17
T22089 402-412 Gene_expression denotes production
T22088 396-401 Protein denotes IL-17
T22087 382-392 Regulation denotes regulation
T22086 279-282 Protein denotes Akt
T22085 185-190 Protein denotes IL-17
T22084 169-181 Positive_regulation denotes upregulation
T22083 139-143 Protein denotes CD28
T22082 93-98 Protein denotes MCP-1
T22081 83-88 Protein denotes IL-15
T22080 49-54 Protein denotes IL-17
T22079 35-45 Gene_expression denotes production
T22078 574-579 Protein denotes IL-17
T22077 396-401 Protein denotes IL-17
T22076 279-282 Protein denotes Akt
T22075 185-190 Protein denotes IL-17
T22074 139-143 Protein denotes CD28
T22073 93-98 Protein denotes MCP-1
T22072 83-88 Protein denotes IL-15
T22071 49-54 Protein denotes IL-17
R12065 T22080 T22079 themeOf IL-17,production
R12066 T22085 T22084 themeOf IL-17,upregulation
R12067 T22088 T22089 themeOf IL-17,production
R12068 T22089 T22087 themeOf production,regulation

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T22407 185-190 Protein denotes IL-17
T22406 139-143 Protein denotes CD28
T22405 93-98 Protein denotes MCP-1
T22404 83-88 Protein denotes IL-15
T22403 49-54 Protein denotes IL-17
T22415 382-392 Regulation denotes regulation
T22414 402-412 Gene_expression denotes production
T22413 169-181 Positive_regulation denotes upregulation
T22412 35-45 Gene_expression denotes production
T22411 71-79 Positive_regulation denotes response
T22410 574-579 Protein denotes IL-17
T22409 396-401 Protein denotes IL-17
T22408 279-282 Protein denotes Akt
R12206 T22403 T22412 themeOf IL-17,production
R12207 T22404 T22411 themeOf IL-15,response
R12208 T22405 T22411 themeOf MCP-1,response
R12209 T22407 T22413 themeOf IL-17,upregulation
R12210 T22409 T22414 themeOf IL-17,production
R12211 T22414 T22415 themeOf production,regulation

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T22618 402-412 Gene_expression denotes production
T22617 382-392 Regulation denotes regulation
T22616 169-181 Positive_regulation denotes upregulation
T22615 35-45 Gene_expression denotes production
T22614 71-79 Positive_regulation denotes response
T22613 574-579 Protein denotes IL-17
T22612 396-401 Protein denotes IL-17
T22611 279-282 Protein denotes Akt
T22610 185-190 Protein denotes IL-17
T22609 139-143 Protein denotes CD28
T22608 93-98 Protein denotes MCP-1
T22607 83-88 Protein denotes IL-15
T22606 49-54 Protein denotes IL-17
R12362 T22606 T22615 themeOf IL-17,production
R12363 T22608 T22614 themeOf MCP-1,response
R12364 T22610 T22616 themeOf IL-17,upregulation
R12365 T22612 T22618 themeOf IL-17,production
R12366 T22618 T22617 themeOf production,regulation

biosemtest

Id Subject Object Predicate Lexical cue
T22196 185-190 UMLS/C1825592 denotes IL-17
T22195 49-54 UMLS/C1825592 denotes IL-17
T22194 35-45 UMLS/C1548180 denotes production
T22193 677-689 UMLS/C1547755 denotes pplications
T22192 83-88 UMLS/C1149222 denotes IL-15
T22191 439-443 UMLS/C0035820 denotes ole
T22190 661-664 UMLS/C0205314 denotes ew
T22189 83-88 UMLS/C0254610 denotes IL-15
T22188 266-269 UMLS/C1550513 denotes via
T22187 592-599 UMLS/C1546471 denotes esults
T22186 245-251 UMLS/C1546471 denotes result
T22185 677-689 UMLS/C0185125 denotes pplications
T22184 283-290 UMLS/C1705987 denotes pathway
T22183 8-16 UMLS/C1511790 denotes detected
T22182 313-323 UMLS/C1879547 denotes ctivation.
T22181 255-265 UMLS/C1879547 denotes activation
T22180 194-203 UMLS/C1879547 denotes activated
T22179 274-278 UMLS/C1150481 denotes PI3K
T22178 356-364 UMLS/C0007634 denotes ellular
T22177 592-599 UMLS/C1280519 denotes esults
T22176 245-251 UMLS/C1280519 denotes result
T22175 496-508 UMLS/C0699748 denotes athogenesis.
T22174 665-676 UMLS/C1553525 denotes herapeutic
T22173 677-689 UMLS/C0870325 denotes pplications
T22172 83-88 UMLS/C1334105 denotes IL-15
T22171 605-610 UMLS/C1524062 denotes dded
T22170 215-223 UMLS/C1705908 denotes patients
T22169 356-364 UMLS/C0178539 denotes ellular
T22168 631-637 UMLS/C0016884 denotes uture
T22167 592-599 UMLS/C0332294 denotes esults
T22166 245-251 UMLS/C0332294 denotes result
T22165 592-599 UMLS/C1274040 denotes esults
T22164 245-251 UMLS/C1274040 denotes result
T22163 8-16 UMLS/C0442726 denotes detected
T22162 110-121 UMLS/C1948023 denotes stimulation
T22161 93-98 UMLS/C1522558 denotes MCP-1
T22160 510-518 UMLS/C1883357 denotes ogether
T22159 665-676 UMLS/C0302350 denotes herapeutic
T22158 554-566 UMLS/C1293116 denotes ntroduction
T22157 169-181 UMLS/C0041904 denotes upregulation
T22156 611-622 UMLS/C0870705 denotes nformation
T22155 274-278 UP/P42336 denotes PI3K
T22154 661-664 UMLS/C1578513 denotes ew
T22153 185-190 UMLS/C1522571 denotes IL-17
T22152 49-54 UMLS/C1522571 denotes IL-17
T22151 215-223 UMLS/C0030705 denotes patients
T22150 110-121 UMLS/C1292856 denotes stimulation
T22149 93-98 UMLS/C1705079 denotes MCP-1
T22148 63-67 UMLS/C1321301 denotes PBMC
T22147 283-290 UMLS/C1704259 denotes pathway
T22146 496-508 UMLS/C0543483 denotes athogenesis.
T22145 185-190 UMLS/C0384648 denotes IL-17
T22144 49-54 UMLS/C0384648 denotes IL-17
T22143 215-223 UMLS/C1578479 denotes patients
T22142 274-278 UMLS/C1368105 denotes PI3K
T22141 531-535 UMLS/C1511726 denotes ata
T22140 329-333 UMLS/C1511726 denotes ata
T22139 215-223 UMLS/C1578483 denotes patients
T22138 215-223 UMLS/C1578480 denotes patients
T22137 215-223 UMLS/C1578481 denotes patients
T22136 215-223 UMLS/C1578486 denotes patients
T22135 232-237 UMLS/C0344312 denotes could
T22134 611-622 UMLS/C1561528 denotes nformation
T22133 215-223 UMLS/C1578484 denotes patients
T22132 215-223 UMLS/C1578485 denotes patients
T22131 71-79 UMLS/C1706817 denotes response
T22130 611-622 UMLS/C1561527 denotes nformation
T22129 611-622 UMLS/C1533716 denotes nformation
T22128 93-98 UMLS/C1337092 denotes MCP-1
T22127 71-79 UMLS/C1704632 denotes response
T22126 232-237 UMLS/C0006823 denotes could
T22125 524-530 UMLS/C0332185 denotes ecent
T22124 215-223 UMLS/C1550655 denotes patients
T22123 19-23 UMLS/C0205172 denotes more
T22122 274-278 UMLS/C1705325 denotes PI3K
T22121 102-106 UMLS/C0205170 denotes well
T22120 185-190 UMLS/C1623218 denotes IL-17
T22119 49-54 UMLS/C1623218 denotes IL-17
T22118 605-610 UMLS/C1720086 denotes dded
T22117 638-657 UMLS/C1513403 denotes olecular targeting
T22116 439-443 UMLS/C1704326 denotes ole
T22115 677-689 UMLS/C1947919 denotes pplications
T22114 365-375 UMLS/C0441712 denotes echanisms
T22113 665-676 UMLS/C0039796 denotes herapeutic
T22112 19-23 UMLS/C0439064 denotes more
T22111 274-278 UMLS/C0285761 denotes PI3K
T22110 80-82 UMLS/C0319022 denotes to
T22109 677-689 UMLS/C2347934 denotes pplications
T22108 334-341 UMLS/C0359589 denotes rovide
T22107 279-282 UP/Q8INB9 denotes Akt
T22106 677-689 UMLS/C1533134 denotes pplications
T22105 661-664 UMLS/C1553390 denotes ew
T22104 462-465 UMLS/C2348947 denotes as
T22103 383-413 UMLS/C1819484 denotes egulation of IL-17 production
T22102 605-610 UMLS/C1883712 denotes dded
T22101 543-553 UMLS/C1272703 denotes uccessful
T22100 447-454 UMLS/C0039194 denotes cells,
T22099 204-211 UMLS/C0039194 denotes T cells
T22098 439-443 UMLS/C1705809 denotes ole
T22097 480-489 UMLS/C0521874 denotes eglected
T22096 439-443 UMLS/C1705812 denotes ole
T22095 665-676 UMLS/C1547427 denotes herapeutic
T22094 439-443 UMLS/C1705810 denotes ole
T22093 439-443 UMLS/C1705811 denotes ole
T22092 365-375 UMLS/C1706376 denotes echanisms
T22091 71-79 UMLS/C0871261 denotes response

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T22341 692-694 NN denotes RA
T22340 689-691 IN denotes in
T22339 676-688 NN denotes applications
T22338 664-675 JJ denotes therapeutic
T22337 660-663 JJ denotes new
T22336 657-659 IN denotes of
T22335 647-656 NN denotes targeting
T22334 637-646 JJ denotes molecular
T22333 630-636 JJ denotes future
T22332 626-629 DT denotes the
T22331 622-625 IN denotes for
T22330 610-621 NN denotes information
T22329 604-609 VB denotes added
T22328 599-603 VB denotes have
T22327 591-598 NN denotes results
T22326 587-590 PRP-DOLLAR- denotes our
T22325 585-586 -COMMA- denotes ,
T22324 583-585 NN denotes RA
T22323 580-582 IN denotes in
T22322 569-579 NN denotes anti-IL-17
T22321 566-568 IN denotes of
T22320 553-565 NN denotes introduction
T22319 542-552 JJ denotes successful
T22318 538-541 DT denotes the
T22317 535-537 IN denotes on
T22316 530-534 NN denotes data
T22315 523-529 JJ denotes recent
T22314 518-522 IN denotes with
T22313 509-517 RB denotes Together
T22312 495-507 NN denotes pathogenesis
T22311 492-494 NN denotes RA
T22310 489-491 IN denotes in
T22309 479-488 VB denotes neglected
T22308 474-478 VB denotes been
T22307 465-473 RB denotes hitherto
T22306 461-464 VB denotes has
T22305 455-460 WDT denotes which
T22304 453-454 -COMMA- denotes ,
T22303 448-453 NN denotes cells
T22302 446-447 NN denotes T
T22301 443-445 IN denotes of
T22300 438-442 NN denotes role
T22299 434-437 DT denotes the
T22298 424-433 VB denotes highlight
T22297 420-423 CC denotes and
T22296 418-419 -COMMA- denotes ,
T22295 416-418 NN denotes RA
T22294 413-415 IN denotes in
T22293 402-412 NN denotes production
T22292 396-401 NN denotes IL-17
T22291 393-395 IN denotes of
T22290 382-392 NN denotes regulation
T22289 378-381 DT denotes the
T22288 375-377 IN denotes of
T22287 364-374 NN denotes mechanisms
T22286 355-363 JJ denotes cellular
T22285 350-354 IN denotes into
T22284 341-349 NN denotes insights
T22283 333-340 VB denotes provide
T22282 328-332 NN denotes data
T22281 324-327 PRP-DOLLAR- denotes Our
T22280 312-322 NN denotes activation
T22279 306-311 NN denotes NF-κB
T22278 296-305 JJ denotes resultant
T22277 291-295 IN denotes with
T22276 283-290 NN denotes pathway
T22275 274-282 NN denotes PI3K/Akt
T22274 270-273 DT denotes the
T22273 266-269 IN denotes via
T22272 255-265 NN denotes activation
T22271 252-254 IN denotes of
T22270 245-251 NN denotes result
T22269 241-244 DT denotes the
T22268 238-240 VB denotes be
T22267 232-237 MD denotes could
T22266 229-231 NN denotes RA
T22265 224-228 IN denotes with
T22264 215-223 NN denotes patients
T22263 212-214 IN denotes in
T22262 206-211 NN denotes cells
T22261 204-205 NN denotes T
T22260 194-203 VB denotes activated
T22259 191-193 IN denotes by
T22258 185-190 NN denotes IL-17
T22257 182-184 IN denotes of
T22256 169-181 NN denotes upregulation
T22255 164-168 IN denotes that
T22254 158-163 VB denotes shown
T22253 153-157 RB denotes also
T22252 148-152 VB denotes have
T22251 145-147 PRP denotes We
T22250 125-143 JJ denotes anti-CD3/anti-CD28
T22249 122-124 IN denotes by
T22248 110-121 NN denotes stimulation
T22247 107-109 IN denotes as
T22246 102-106 RB denotes well
T22245 99-101 RB denotes as
T22244 93-98 NN denotes MCP-1
T22243 89-92 CC denotes and
T22242 83-88 NN denotes IL-15
T22241 80-82 TO denotes to
T22240 71-79 NN denotes response
T22239 68-70 IN denotes in
T22238 63-67 NN denotes PBMC
T22237 60-62 NN denotes RA
T22236 55-59 IN denotes from
T22235 49-54 NN denotes IL-17
T22234 46-48 IN denotes of
T22233 35-45 NN denotes production
T22232 24-34 JJ denotes pronounced
T22231 19-23 RB denotes more
T22230 17-18 DT denotes a
T22229 8-16 VB denotes detected
T22228 3-7 VB denotes have
T22227 0-2 PRP denotes We
R12078 T22227 T22228 arg1Of We,have
R12079 T22227 T22229 arg1Of We,detected
R12080 T22229 T22228 arg2Of detected,have
R12081 T22229 T22239 arg1Of detected,in
R12082 T22232 T22231 arg1Of pronounced,more
R12083 T22233 T22229 arg2Of production,detected
R12084 T22233 T22230 arg1Of production,a
R12085 T22233 T22232 arg1Of production,pronounced
R12086 T22233 T22234 arg1Of production,of
R12087 T22233 T22236 arg1Of production,from
R12088 T22235 T22234 arg2Of IL-17,of
R12089 T22238 T22236 arg2Of PBMC,from
R12090 T22238 T22237 arg1Of PBMC,RA
R12091 T22240 T22239 arg2Of response,in
R12092 T22240 T22241 arg1Of response,to
R12093 T22242 T22243 arg1Of IL-15,and
R12094 T22243 T22247 arg1Of and,as
R12095 T22244 T22243 arg2Of MCP-1,and
R12096 T22247 T22241 arg2Of as,to
R12097 T22247 T22245 arg1Of as,as
R12098 T22247 T22246 arg1Of as,well
R12099 T22248 T22247 arg2Of stimulation,as
R12100 T22248 T22249 arg1Of stimulation,by
R12101 T22250 T22249 arg2Of anti-CD3/anti-CD28,by
R12102 T22251 T22252 arg1Of We,have
R12103 T22251 T22254 arg1Of We,shown
R12104 T22254 T22252 arg2Of shown,have
R12105 T22254 T22253 arg1Of shown,also
R12106 T22256 T22257 arg1Of upregulation,of
R12107 T22256 T22259 arg1Of upregulation,by
R12108 T22256 T22263 arg1Of upregulation,in
R12109 T22256 T22267 arg1Of upregulation,could
R12110 T22256 T22268 arg1Of upregulation,be
R12111 T22258 T22257 arg2Of IL-17,of
R12112 T22262 T22259 arg2Of cells,by
R12113 T22262 T22260 arg2Of cells,activated
R12114 T22262 T22261 arg1Of cells,T
R12115 T22264 T22263 arg2Of patients,in
R12116 T22264 T22265 arg1Of patients,with
R12117 T22266 T22265 arg2Of RA,with
R12118 T22268 T22254 arg2Of be,shown
R12119 T22268 T22255 arg1Of be,that
R12120 T22268 T22267 arg2Of be,could
R12121 T22270 T22268 arg2Of result,be
R12122 T22270 T22269 arg1Of result,the
R12123 T22270 T22271 arg1Of result,of
R12124 T22270 T22273 arg1Of result,via
R12125 T22272 T22271 arg2Of activation,of
R12126 T22276 T22273 arg2Of pathway,via
R12127 T22276 T22274 arg1Of pathway,the
R12128 T22276 T22275 arg1Of pathway,PI3K/Akt
R12129 T22276 T22277 arg1Of pathway,with
R12130 T22280 T22277 arg2Of activation,with
R12131 T22280 T22278 arg1Of activation,resultant
R12132 T22280 T22279 arg1Of activation,NF-κB
R12133 T22282 T22281 arg1Of data,Our
R12134 T22282 T22283 arg1Of data,provide
R12135 T22282 T22298 arg1Of data,highlight
R12136 T22283 T22285 arg1Of provide,into
R12137 T22283 T22297 arg1Of provide,and
R12138 T22284 T22283 arg2Of insights,provide
R12139 T22287 T22285 arg2Of mechanisms,into
R12140 T22287 T22286 arg1Of mechanisms,cellular
R12141 T22287 T22288 arg1Of mechanisms,of
R12142 T22290 T22288 arg2Of regulation,of
R12143 T22290 T22289 arg1Of regulation,the
R12144 T22290 T22291 arg1Of regulation,of
R12145 T22293 T22291 arg2Of production,of
R12146 T22293 T22292 arg1Of production,IL-17
R12147 T22293 T22294 arg1Of production,in
R12148 T22295 T22294 arg2Of RA,in
R12149 T22297 T22296 arg1Of and,","
R12150 T22298 T22297 arg2Of highlight,and
R12151 T22300 T22298 arg2Of role,highlight
R12152 T22300 T22299 arg1Of role,the
R12153 T22300 T22301 arg1Of role,of
R12154 T22300 T22304 arg1Of role,","
R12155 T22300 T22305 arg1Of role,which
R12156 T22300 T22306 arg1Of role,has
R12157 T22300 T22308 arg1Of role,been
R12158 T22300 T22309 arg2Of role,neglected
R12159 T22303 T22301 arg2Of cells,of
R12160 T22303 T22302 arg1Of cells,T
R12161 T22309 T22306 arg2Of neglected,has
R12162 T22309 T22307 arg1Of neglected,hitherto
R12163 T22309 T22308 arg2Of neglected,been
R12164 T22309 T22310 arg1Of neglected,in
R12165 T22312 T22310 arg2Of pathogenesis,in
R12166 T22312 T22311 arg1Of pathogenesis,RA
R12167 T22316 T22314 arg2Of data,with
R12168 T22316 T22315 arg1Of data,recent
R12169 T22316 T22317 arg1Of data,on
R12170 T22320 T22317 arg2Of introduction,on
R12171 T22320 T22318 arg1Of introduction,the
R12172 T22320 T22319 arg1Of introduction,successful
R12173 T22320 T22321 arg1Of introduction,of
R12174 T22320 T22323 arg1Of introduction,in
R12175 T22322 T22321 arg2Of anti-IL-17,of
R12176 T22324 T22323 arg2Of RA,in
R12177 T22327 T22326 arg1Of results,our
R12178 T22327 T22328 arg1Of results,have
R12179 T22327 T22329 arg1Of results,added
R12180 T22329 T22313 arg1Of added,Together
R12181 T22329 T22314 arg1Of added,with
R12182 T22329 T22325 arg1Of added,","
R12183 T22329 T22328 arg2Of added,have
R12184 T22330 T22329 arg2Of information,added
R12185 T22330 T22331 arg1Of information,for
R12186 T22335 T22331 arg2Of targeting,for
R12187 T22335 T22332 arg1Of targeting,the
R12188 T22335 T22333 arg1Of targeting,future
R12189 T22335 T22334 arg1Of targeting,molecular
R12190 T22335 T22336 arg1Of targeting,of
R12191 T22338 T22337 arg1Of therapeutic,new
R12192 T22339 T22336 arg2Of applications,of
R12193 T22339 T22338 arg1Of applications,therapeutic
R12194 T22339 T22340 arg1Of applications,in
R12195 T22341 T22340 arg2Of RA,in

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T22349 574-579 Protein denotes IL-17
T22348 396-401 Protein denotes IL-17
T22347 279-282 Protein denotes Akt
T22346 185-190 Protein denotes IL-17
T22345 139-143 Protein denotes CD28
T22344 93-98 Protein denotes MCP-1
T22343 83-88 Protein denotes IL-15
T22342 49-54 Protein denotes IL-17

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T22402 139-143 http://www.uniprot.org/uniprot/P10747 denotes CD28
T22401 130-133 http://www.uniprot.org/uniprot/P09693 denotes CD3
T22400 130-133 http://www.uniprot.org/uniprot/P07766 denotes CD3
T22399 130-133 http://www.uniprot.org/uniprot/P04234 denotes CD3
T22398 130-133 http://www.uniprot.org/uniprot/P20963 denotes CD3
T22397 83-88 http://www.uniprot.org/uniprot/P40933 denotes IL-15
T22396 574-579 http://www.uniprot.org/uniprot/Q16552 denotes IL-17
T22395 396-401 http://www.uniprot.org/uniprot/Q16552 denotes IL-17
T22394 185-190 http://www.uniprot.org/uniprot/Q16552 denotes IL-17
T22393 49-54 http://www.uniprot.org/uniprot/Q16552 denotes IL-17

GO-BP

Id Subject Object Predicate Lexical cue
T22211 495-507 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T22210 382-392 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T22209 355-363 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T22208 274-278 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T22207 93-96 http://purl.obolibrary.org/obo/GO_0004298 denotes MCP
T22206 71-88 http://purl.obolibrary.org/obo/GO_0071350 denotes response to IL-15
T22205 71-88 http://purl.obolibrary.org/obo/GO_0070672 denotes response to IL-15
T22204 396-412 http://purl.obolibrary.org/obo/GO_0032620 denotes IL-17 production
T22203 35-54 http://purl.obolibrary.org/obo/GO_0032620 denotes production of IL-17
T22202 396-412 http://purl.obolibrary.org/obo/GO_0032660 denotes IL-17 production
T22201 35-54 http://purl.obolibrary.org/obo/GO_0032660 denotes production of IL-17

GO-MF

Id Subject Object Predicate Lexical cue
T22356 274-278 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T22355 93-96 http://purl.obolibrary.org/obo/GO_0004298 denotes MCP
T22354 83-88 http://purl.obolibrary.org/obo/GO_0016170 denotes IL-15
T22353 574-579 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17
T22352 396-401 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17
T22351 185-190 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17
T22350 49-54 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17

GO-CC

Id Subject Object Predicate Lexical cue
T22358 448-453 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T22357 206-211 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T22200 509-695 Sentence denotes Together with recent data on the successful introduction of anti-IL-17 in RA, our results have added information for the future molecular targeting of new therapeutic applications in RA.
T22199 324-508 Sentence denotes Our data provide insights into cellular mechanisms of the regulation of IL-17 production in RA, and highlight the role of T cells, which has hitherto been neglected in RA pathogenesis.
T22198 145-323 Sentence denotes We have also shown that upregulation of IL-17 by activated T cells in patients with RA could be the result of activation via the PI3K/Akt pathway with resultant NF-κB activation.
T22197 0-144 Sentence denotes We have detected a more pronounced production of IL-17 from RA PBMC in response to IL-15 and MCP-1 as well as stimulation by anti-CD3/anti-CD28.
T196 0-144 Sentence denotes We have detected a more pronounced production of IL-17 from RA PBMC in response to IL-15 and MCP-1 as well as stimulation by anti-CD3/anti-CD28.
T197 145-323 Sentence denotes We have also shown that upregulation of IL-17 by activated T cells in patients with RA could be the result of activation via the PI3K/Akt pathway with resultant NF-κB activation.
T198 324-508 Sentence denotes Our data provide insights into cellular mechanisms of the regulation of IL-17 production in RA, and highlight the role of T cells, which has hitherto been neglected in RA pathogenesis.
T199 509-695 Sentence denotes Together with recent data on the successful introduction of anti-IL-17 in RA, our results have added information for the future molecular targeting of new therapeutic applications in RA.

simple1

Id Subject Object Predicate Lexical cue
T22392 574-579 Protein denotes IL-17
T22391 396-401 Protein denotes IL-17
T22390 279-282 Protein denotes Akt
T22389 185-190 Protein denotes IL-17
T22388 139-143 Protein denotes CD28
T22387 93-98 Protein denotes MCP-1
T22386 83-88 Protein denotes IL-15
T22385 49-54 Protein denotes IL-17

DLUT931

Id Subject Object Predicate Lexical cue
T22430 553-565 Gene_expression denotes introduction
T22429 382-392 Regulation denotes regulation
T22428 402-412 Gene_expression denotes production
T22427 169-181 Positive_regulation denotes upregulation
T22426 24-34 Positive_regulation denotes pronounced
T22425 71-79 Positive_regulation denotes response
T22424 35-45 Gene_expression denotes production
T22423 574-579 Protein denotes IL-17
T22422 396-401 Protein denotes IL-17
T22421 279-282 Protein denotes Akt
T22420 185-190 Protein denotes IL-17
T22419 139-143 Protein denotes CD28
T22418 93-98 Protein denotes MCP-1
T22417 83-88 Protein denotes IL-15
T22416 49-54 Protein denotes IL-17
R12212 T22416 T22424 themeOf IL-17,production
R12213 T22417 T22425 themeOf IL-15,response
R12214 T22418 T22425 themeOf MCP-1,response
R12215 T22420 T22427 themeOf IL-17,upregulation
R12216 T22422 T22428 themeOf IL-17,production
R12217 T22423 T22430 themeOf IL-17,introduction
R12218 T22424 T22426 themeOf production,pronounced
R12219 T22428 T22429 themeOf production,regulation

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T22605 393-418 Gene_expression denotes of IL-17 production in RA
T22604 378-418 Regulation denotes the regulation of IL-17 production in RA
T22603 538-586 Gene_expression denotes the successful introduction of anti-IL-17 in RA,
T22602 0-121 Gene_expression denotes We have detected a more pronounced production of IL-17 from RA PBMC in response to IL-15 and MCP-1 as well as stimulation
T22601 169-231 Positive_regulation denotes upregulation of IL-17 by activated T cells in patients with RA
T22600 443-453 Entity denotes of T cells
T22599 274-282 Protein denotes PI3K/Akt
T22598 492-507 Protein denotes RA pathogenesis
T22597 416-418 Protein denotes RA
T22596 182-190 Protein denotes of IL-17
T22595 583-585 Protein denotes RA
T22594 306-322 Protein denotes NF-κB activation
T22593 279-282 Protein denotes Akt
T22592 46-54 Protein denotes of IL-17
T22591 93-98 Protein denotes MCP-1
T22590 274-282 Protein denotes PI3K/Akt
T22589 692-694 Protein denotes RA
T22588 229-231 Protein denotes RA
T22587 396-401 Protein denotes IL-17
T22586 191-211 Entity denotes by activated T cells
T22585 60-62 Protein denotes RA
T22584 566-579 Protein denotes of anti-IL-17
T22583 60-67 Entity denotes RA PBMC
T22582 83-88 Protein denotes IL-15
R12356 T22584 T22603 themeOf of anti-IL-17,"the successful introduction of anti-IL-17 in RA,"
R12357 T22586 T22601 causeOf by activated T cells,upregulation of IL-17 by activated T cells in patients with RA
R12358 T22587 T22605 themeOf IL-17,of IL-17 production in RA
R12359 T22592 T22602 themeOf of IL-17,We have detected a more pronounced production of IL-17 from RA PBMC in response to IL-15 and MCP-1 as well as stimulation
R12360 T22596 T22601 themeOf of IL-17,upregulation of IL-17 by activated T cells in patients with RA
R12361 T22605 T22604 themeOf of IL-17 production in RA,the regulation of IL-17 production in RA

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T22563 694-695 . denotes .
T22562 692-694 NNP denotes RA
T22561 689-691 IN denotes in
T22560 676-688 NNS denotes applications
T22559 664-675 JJ denotes therapeutic
T22558 660-663 JJ denotes new
T22557 657-659 IN denotes of
T22556 647-656 VBG denotes targeting
T22555 637-646 JJ denotes molecular
T22554 630-636 JJ denotes future
T22553 626-629 DT denotes the
T22552 622-625 IN denotes for
T22551 610-621 NN denotes information
T22550 604-609 VBN denotes added
T22549 599-603 VBP denotes have
T22548 591-598 NNS denotes results
T22547 587-590 PRP$ denotes our
T22546 585-586 , denotes ,
T22545 583-585 NNP denotes RA
T22544 580-582 IN denotes in
T22543 569-579 NN denotes anti-IL-17
T22542 566-568 IN denotes of
T22541 553-565 NN denotes introduction
T22540 542-552 JJ denotes successful
T22539 538-541 DT denotes the
T22538 535-537 IN denotes on
T22537 530-534 NNS denotes data
T22536 523-529 JJ denotes recent
T22535 518-522 IN denotes with
T22534 509-517 RB denotes Together
T22533 507-508 . denotes .
T22532 495-507 NN denotes pathogenesis
T22531 492-494 NNP denotes RA
T22530 489-491 IN denotes in
T22529 479-488 VBN denotes neglected
T22528 474-478 VBN denotes been
T22527 465-473 RB denotes hitherto
T22526 461-464 VBZ denotes has
T22525 455-460 WDT denotes which
T22524 453-454 , denotes ,
T22523 448-453 NNS denotes cells
T22522 446-447 NNP denotes T
T22521 443-445 IN denotes of
T22520 438-442 NN denotes role
T22519 434-437 DT denotes the
T22518 424-433 VB denotes highlight
T22517 420-423 CC denotes and
T22516 418-419 , denotes ,
T22515 416-418 NNP denotes RA
T22514 413-415 IN denotes in
T22513 402-412 NN denotes production
T22512 396-401 JJ denotes IL-17
T22511 393-395 IN denotes of
T22510 382-392 NN denotes regulation
T22509 378-381 DT denotes the
T22508 375-377 IN denotes of
T22507 364-374 NNS denotes mechanisms
T22506 355-363 JJ denotes cellular
T22505 350-354 IN denotes into
T22504 341-349 NNS denotes insights
T22503 333-340 VBP denotes provide
T22502 328-332 NNS denotes data
T22501 324-327 PRP$ denotes Our
T22500 322-323 . denotes .
T22499 312-322 NN denotes activation
T22498 306-311 NN denotes NF-κB
T22497 296-305 JJ denotes resultant
T22496 291-295 IN denotes with
T22495 283-290 NN denotes pathway
T22494 274-282 JJ denotes PI3K/Akt
T22493 270-273 DT denotes the
T22492 266-269 IN denotes via
T22491 255-265 NN denotes activation
T22490 252-254 IN denotes of
T22489 245-251 NN denotes result
T22488 241-244 DT denotes the
T22487 238-240 VB denotes be
T22486 232-237 MD denotes could
T22485 229-231 NNP denotes RA
T22484 224-228 IN denotes with
T22483 215-223 NNS denotes patients
T22482 212-214 IN denotes in
T22481 206-211 NNS denotes cells
T22480 204-205 NNP denotes T
T22479 194-203 VBN denotes activated
T22478 191-193 IN denotes by
T22477 185-190 NNP denotes IL-17
T22476 182-184 IN denotes of
T22475 169-181 NN denotes upregulation
T22474 164-168 IN denotes that
T22473 158-163 VBN denotes shown
T22472 153-157 RB denotes also
T22471 148-152 VBP denotes have
T22470 145-147 PRP denotes We
T22469 143-144 . denotes .
T22468 134-143 NN denotes anti-CD28
T22467 133-134 NN denotes /
T22466 125-133 JJ denotes anti-CD3
T22465 122-124 IN denotes by
T22464 110-121 NN denotes stimulation
T22463 107-109 IN denotes as
T22462 102-106 RB denotes well
T22461 99-101 RB denotes as
T22460 93-98 NNP denotes MCP-1
T22459 89-92 CC denotes and
T22458 83-88 NNP denotes IL-15
T22457 80-82 TO denotes to
T22456 71-79 NN denotes response
T22455 68-70 IN denotes in
T22454 63-67 NNP denotes PBMC
T22453 60-62 NNP denotes RA
T22452 55-59 IN denotes from
T22451 49-54 NNP denotes IL-17
T22450 46-48 IN denotes of
T22449 35-45 NN denotes production
T22448 24-34 JJ denotes pronounced
T22447 19-23 RBR denotes more
T22446 17-18 DT denotes a
T22445 8-16 VBN denotes detected
T22444 3-7 VBP denotes have
T22443 0-2 PRP denotes We
R12228 T22443 T22445 nsubj We,detected
R12229 T22444 T22445 aux have,detected
R12230 T22445 T22445 ROOT detected,detected
R12231 T22446 T22449 det a,production
R12232 T22447 T22448 advmod more,pronounced
R12233 T22448 T22449 amod pronounced,production
R12234 T22449 T22445 dobj production,detected
R12235 T22450 T22449 prep of,production
R12236 T22451 T22450 pobj IL-17,of
R12237 T22452 T22449 prep from,production
R12238 T22453 T22454 compound RA,PBMC
R12239 T22454 T22452 pobj PBMC,from
R12240 T22455 T22449 prep in,production
R12241 T22456 T22455 pobj response,in
R12242 T22457 T22456 prep to,response
R12243 T22458 T22457 pobj IL-15,to
R12244 T22459 T22458 cc and,IL-15
R12245 T22460 T22458 conj MCP-1,IL-15
R12246 T22461 T22463 advmod as,as
R12247 T22462 T22463 advmod well,as
R12248 T22463 T22456 cc as,response
R12249 T22464 T22456 conj stimulation,response
R12250 T22465 T22449 prep by,production
R12251 T22466 T22468 amod anti-CD3,anti-CD28
R12252 T22467 T22468 compound /,anti-CD28
R12253 T22468 T22465 pobj anti-CD28,by
R12254 T22469 T22445 punct .,detected
R12255 T22470 T22473 nsubj We,shown
R12256 T22471 T22473 aux have,shown
R12257 T22472 T22473 advmod also,shown
R12258 T22473 T22473 ROOT shown,shown
R12259 T22474 T22487 mark that,be
R12260 T22475 T22487 nsubj upregulation,be
R12261 T22476 T22475 prep of,upregulation
R12262 T22477 T22476 pobj IL-17,of
R12263 T22478 T22475 prep by,upregulation
R12264 T22479 T22481 amod activated,cells
R12265 T22480 T22481 compound T,cells
R12266 T22481 T22478 pobj cells,by
R12267 T22482 T22475 prep in,upregulation
R12268 T22483 T22482 pobj patients,in
R12269 T22484 T22475 prep with,upregulation
R12270 T22485 T22484 pobj RA,with
R12271 T22486 T22487 aux could,be
R12272 T22487 T22473 ccomp be,shown
R12273 T22488 T22489 det the,result
R12274 T22489 T22487 attr result,be
R12275 T22490 T22489 prep of,result
R12276 T22491 T22490 pobj activation,of
R12277 T22492 T22487 prep via,be
R12278 T22493 T22495 det the,pathway
R12279 T22494 T22495 amod PI3K/Akt,pathway
R12280 T22495 T22492 pobj pathway,via
R12281 T22496 T22495 prep with,pathway
R12282 T22497 T22499 amod resultant,activation
R12283 T22498 T22499 compound NF-κB,activation
R12284 T22499 T22496 pobj activation,with
R12285 T22500 T22473 punct .,shown
R12286 T22501 T22502 poss Our,data
R12287 T22502 T22503 nsubj data,provide
R12288 T22503 T22503 ROOT provide,provide
R12289 T22504 T22503 dobj insights,provide
R12290 T22505 T22504 prep into,insights
R12291 T22506 T22507 amod cellular,mechanisms
R12292 T22507 T22505 pobj mechanisms,into
R12293 T22508 T22507 prep of,mechanisms
R12294 T22509 T22510 det the,regulation
R12295 T22510 T22508 pobj regulation,of
R12296 T22511 T22510 prep of,regulation
R12297 T22512 T22513 amod IL-17,production
R12298 T22513 T22511 pobj production,of
R12299 T22514 T22513 prep in,production
R12300 T22515 T22514 pobj RA,in
R12301 T22516 T22503 punct ",",provide
R12302 T22517 T22503 cc and,provide
R12303 T22518 T22503 conj highlight,provide
R12304 T22519 T22520 det the,role
R12305 T22520 T22518 dobj role,highlight
R12306 T22521 T22520 prep of,role
R12307 T22522 T22523 compound T,cells
R12308 T22523 T22521 pobj cells,of
R12309 T22524 T22523 punct ",",cells
R12310 T22525 T22529 nsubj which,neglected
R12311 T22526 T22529 aux has,neglected
R12312 T22527 T22529 advmod hitherto,neglected
R12313 T22528 T22529 auxpass been,neglected
R12314 T22529 T22523 relcl neglected,cells
R12315 T22530 T22529 prep in,neglected
R12316 T22531 T22532 compound RA,pathogenesis
R12317 T22532 T22530 pobj pathogenesis,in
R12318 T22533 T22503 punct .,provide
R12319 T22534 T22535 advmod Together,with
R12320 T22535 T22550 prep with,added
R12321 T22536 T22537 amod recent,data
R12322 T22537 T22535 pobj data,with
R12323 T22538 T22537 prep on,data
R12324 T22539 T22541 det the,introduction
R12325 T22540 T22541 amod successful,introduction
R12326 T22541 T22538 pobj introduction,on
R12327 T22542 T22541 prep of,introduction
R12328 T22543 T22542 pobj anti-IL-17,of
R12329 T22544 T22541 prep in,introduction
R12330 T22545 T22544 pobj RA,in
R12331 T22546 T22550 punct ",",added
R12332 T22547 T22548 poss our,results
R12333 T22548 T22550 nsubj results,added
R12334 T22549 T22550 aux have,added
R12335 T22550 T22550 ROOT added,added
R12336 T22551 T22550 dobj information,added
R12337 T22552 T22550 prep for,added
R12338 T22553 T22556 det the,targeting
R12339 T22554 T22556 amod future,targeting
R12340 T22555 T22556 amod molecular,targeting
R12341 T22556 T22552 pobj targeting,for
R12342 T22557 T22556 prep of,targeting
R12343 T22558 T22560 amod new,applications
R12344 T22559 T22560 amod therapeutic,applications
R12345 T22560 T22557 pobj applications,of
R12346 T22561 T22560 prep in,applications
R12347 T22562 T22561 pobj RA,in
R12348 T22563 T22550 punct .,added

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T22384 553-565 Gene_expression denotes introduction
T22383 569-579 Protein denotes anti-IL-17
T22382 312-322 Positive_regulation denotes activation
T22381 169-181 Positive_regulation denotes upregulation
T22380 306-311 Protein denotes NF-κB
T22379 279-282 Protein denotes Akt
T22378 274-278 Protein denotes PI3K
T22377 185-190 Protein denotes IL-17
T22376 71-79 Positive_regulation denotes response
T22375 71-79 Positive_regulation denotes response
T22374 35-45 Gene_expression denotes production
T22373 35-45 Gene_expression denotes production
T22372 134-143 Protein denotes anti-CD28
T22371 125-133 Protein denotes anti-CD3
T22370 93-98 Protein denotes MCP-1
T22369 83-88 Protein denotes IL-15
T22368 60-67 Protein denotes RA PBMC
T22367 49-54 Protein denotes IL-17
R12199 T22367 T22373 themeOf IL-17,production
R12200 T22368 T22374 themeOf RA PBMC,production
R12201 T22369 T22375 themeOf IL-15,response
R12202 T22370 T22376 themeOf MCP-1,response
R12203 T22377 T22381 themeOf IL-17,upregulation
R12204 T22380 T22382 themeOf NF-κB,activation
R12205 T22383 T22384 themeOf anti-IL-17,introduction

testone

Id Subject Object Predicate Lexical cue
T22070 402-412 Gene_expression denotes production
T22069 382-392 Regulation denotes regulation
T22068 169-181 Positive_regulation denotes upregulation
T22067 68-82 Positive_regulation denotes in response to
T22066 35-45 Gene_expression denotes production
T22065 574-579 Protein denotes IL-17
T22064 396-401 Protein denotes IL-17
T22063 279-282 Protein denotes Akt
T22062 185-190 Protein denotes IL-17
T22061 139-143 Protein denotes CD28
T22060 93-98 Protein denotes MCP-1
T22059 83-88 Protein denotes IL-15
T22058 49-54 Protein denotes IL-17
R12057 T22058 T22066 themeOf IL-17,production
R12058 T22059 T22067 causeOf IL-15,in response to
R12059 T22060 T22067 causeOf MCP-1,in response to
R12060 T22061 T22067 causeOf CD28,in response to
R12061 T22062 T22068 themeOf IL-17,upregulation
R12062 T22064 T22070 themeOf IL-17,production
R12063 T22066 T22067 themeOf production,in response to
R12064 T22070 T22069 themeOf production,regulation