PubMed:18274892 JSON TXT

A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH. GM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate.

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GlyCosmos6-UBERON (0) glycosmos_glycans (0) GlyCosmos600-GlycoGene3 (0) GlyCosmos600-GlycoGenes2 (0) GlyCosmos600-Glycan-Motif-Structure (6) GlyCosmos600-CLO (0) NCBITAXON (0) GlyCosmos6-Glycan-Motif-Image (3) GlyCosmos6-HP (0) GlyCosmos6-docs (0) Glycosmos6-GlycoEpitope (3) sentences (6) GlyCosmos6-Glycan-Motif-Structure (6) Glycosmos6-MAT (0) GlyCosmos6-CLO (1) GlyCosmos600-GlycoEpitope (3) mondo_disease (0) GlyCosmos600-FMA (1) GlyCosmos-GlycanStructure-c (0) glycoprotein (0) GlyCosmos600-GlycanStructure (0) GlyCosmos600-GlycoGenes (0) glycosmos-test-glycan-structure (6) glycosmos-test-structure-v1 (6) GlyCosmos600-docs (0) GlyCosmos600-MAT (0) GlyCosmos600-GlycoProteins (0) Glycan-Abbreviation (0) pubmed-enju-pas (63) GlycoConjugate-collection (0)

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PubMed:18274892 JSONTXT

projects that include this document

PubMed:18274892 JSON TXT