PubMed:18274892 JSONTXT

{"project":"GlyCosmos600-Glycan-Motif-Structure","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T2","span":{"begin":35,"end":38},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T3","span":{"begin":93,"end":96},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T4","span":{"begin":93,"end":96},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T5","span":{"begin":388,"end":391},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T6","span":{"begin":388,"end":391},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"Glycan_Motif"},{"id":"T3","span":{"begin":93,"end":96},"obj":"Glycan_Motif"},{"id":"T5","span":{"begin":388,"end":391},"obj":"Glycan_Motif"}],"attributes":[{"id":"A1","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR"},{"id":"A2","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI"},{"id":"A3","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR"},{"id":"A4","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI"},{"id":"A5","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR"},{"id":"A6","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"Glycosmos6-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"T2","span":{"begin":93,"end":96},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"T3","span":{"begin":388,"end":391},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":93,"end":247},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":248,"end":414},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"T2","span":{"begin":93,"end":247},"obj":"Sentence"},{"id":"T3","span":{"begin":248,"end":414},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T2","span":{"begin":35,"end":38},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T3","span":{"begin":93,"end":96},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T4","span":{"begin":93,"end":96},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T5","span":{"begin":388,"end":391},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T6","span":{"begin":388,"end":391},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos600-GlycoEpitope","denotations":[{"id":"PD-GlycoEpitope-B_T1","span":{"begin":35,"end":38},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"PD-GlycoEpitope-B_T2","span":{"begin":93,"end":96},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"PD-GlycoEpitope-B_T3","span":{"begin":388,"end":391},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"glycosmos-test-glycan-structure","denotations":[{"id":"PD-GlycanStructures-B_T1","span":{"begin":35,"end":38},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T2","span":{"begin":93,"end":96},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T3","span":{"begin":388,"end":391},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T4","span":{"begin":35,"end":38},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"},{"id":"PD-GlycanStructures-B_T5","span":{"begin":93,"end":96},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"},{"id":"PD-GlycanStructures-B_T6","span":{"begin":388,"end":391},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"glycosmos-test-structure-v1","denotations":[{"id":"PD-GlycanStructures-B_T1","span":{"begin":35,"end":38},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T4","span":{"begin":35,"end":38},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"},{"id":"PD-GlycanStructures-B_T2","span":{"begin":93,"end":96},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T5","span":{"begin":93,"end":96},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"},{"id":"PD-GlycanStructures-B_T3","span":{"begin":388,"end":391},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa13/trivialname"},{"id":"PD-GlycanStructures-B_T6","span":{"begin":388,"end":391},"obj":"http://rdf.glyconavi.org/CarTNa/CarTNa96/trivialname"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"pubmed-enju-pas","denotations":[{"id":"EnjuParser_T0","span":{"begin":0,"end":1},"obj":"DT"},{"id":"EnjuParser_T1","span":{"begin":2,"end":8},"obj":"RB"},{"id":"EnjuParser_T2","span":{"begin":9,"end":18},"obj":"JJ"},{"id":"EnjuParser_T3","span":{"begin":19,"end":31},"obj":"NN"},{"id":"EnjuParser_T4","span":{"begin":32,"end":34},"obj":"IN"},{"id":"EnjuParser_T5","span":{"begin":35,"end":38},"obj":"NN"},{"id":"EnjuParser_T6","span":{"begin":39,"end":46},"obj":"NN"},{"id":"EnjuParser_T7","span":{"begin":47,"end":62},"obj":"NN"},{"id":"EnjuParser_T8","span":{"begin":63,"end":66},"obj":"CC"},{"id":"EnjuParser_T9","span":{"begin":67,"end":70},"obj":"PRP-DOLLAR-"},{"id":"EnjuParser_T10","span":{"begin":71,"end":82},"obj":"NN"},{"id":"EnjuParser_T11","span":{"begin":83,"end":87},"obj":"IN"},{"id":"EnjuParser_T12","span":{"begin":88,"end":91},"obj":"NN"},{"id":"EnjuParser_T13","span":{"begin":93,"end":96},"obj":"NN"},{"id":"EnjuParser_T14","span":{"begin":97,"end":104},"obj":"NN"},{"id":"EnjuParser_T15","span":{"begin":105,"end":120},"obj":"NN"},{"id":"EnjuParser_T16","span":{"begin":121,"end":124},"obj":"VBD"},{"id":"EnjuParser_T17","span":{"begin":125,"end":136},"obj":"VBN"},{"id":"EnjuParser_T18","span":{"begin":137,"end":139},"obj":"IN"},{"id":"EnjuParser_T19","span":{"begin":140,"end":141},"obj":"DT"},{"id":"EnjuParser_T20","span":{"begin":142,"end":154},"obj":"NN"},{"id":"EnjuParser_T21","span":{"begin":155,"end":157},"obj":"IN"},{"id":"EnjuParser_T22","span":{"begin":158,"end":170},"obj":"NN"},{"id":"EnjuParser_T23","span":{"begin":170,"end":171},"obj":"-LRB-"},{"id":"EnjuParser_T24","span":{"begin":171,"end":174},"obj":"NN"},{"id":"EnjuParser_T25","span":{"begin":174,"end":175},"obj":"-RRB-"},{"id":"EnjuParser_T26","span":{"begin":175,"end":179},"obj":"JJ"},{"id":"EnjuParser_T27","span":{"begin":180,"end":188},"obj":"NN"},{"id":"EnjuParser_T28","span":{"begin":189,"end":192},"obj":"CC"},{"id":"EnjuParser_T29","span":{"begin":193,"end":201},"obj":"NN"},{"id":"EnjuParser_T30","span":{"begin":201,"end":202},"obj":"-LRB-"},{"id":"EnjuParser_T31","span":{"begin":202,"end":205},"obj":"NN"},{"id":"EnjuParser_T32","span":{"begin":205,"end":206},"obj":"-RRB-"},{"id":"EnjuParser_T33","span":{"begin":206,"end":211},"obj":"NN"},{"id":"EnjuParser_T34","span":{"begin":212,"end":217},"obj":"NN"},{"id":"EnjuParser_T35","span":{"begin":218,"end":220},"obj":"IN"},{"id":"EnjuParser_T36","span":{"begin":221,"end":222},"obj":"DT"},{"id":"EnjuParser_T37","span":{"begin":223,"end":229},"obj":"RB"},{"id":"EnjuParser_T38","span":{"begin":230,"end":239},"obj":"JJ"},{"id":"EnjuParser_T39","span":{"begin":240,"end":246},"obj":"NN"},{"id":"EnjuParser_T40","span":{"begin":248,"end":253},"obj":"IN"},{"id":"EnjuParser_T41","span":{"begin":254,"end":266},"obj":"NN"},{"id":"EnjuParser_T42","span":{"begin":267,"end":269},"obj":"IN"},{"id":"EnjuParser_T43","span":{"begin":270,"end":285},"obj":"NN"},{"id":"EnjuParser_T44","span":{"begin":286,"end":288},"obj":"TO"},{"id":"EnjuParser_T45","span":{"begin":289,"end":292},"obj":"DT"},{"id":"EnjuParser_T46","span":{"begin":293,"end":308},"obj":"NN"},{"id":"EnjuParser_T47","span":{"begin":308,"end":309},"obj":"-COMMA-"},{"id":"EnjuParser_T48","span":{"begin":310,"end":312},"obj":"PRP"},{"id":"EnjuParser_T49","span":{"begin":313,"end":316},"obj":"VBD"},{"id":"EnjuParser_T50","span":{"begin":317,"end":324},"obj":"VBN"},{"id":"EnjuParser_T51","span":{"begin":325,"end":327},"obj":"TO"},{"id":"EnjuParser_T52","span":{"begin":328,"end":347},"obj":"JJ"},{"id":"EnjuParser_T53","span":{"begin":348,"end":351},"obj":"NN"},{"id":"EnjuParser_T54","span":{"begin":352,"end":359},"obj":"NN"},{"id":"EnjuParser_T55","span":{"begin":360,"end":367},"obj":"NN"},{"id":"EnjuParser_T56","span":{"begin":368,"end":370},"obj":"TO"},{"id":"EnjuParser_T57","span":{"begin":371,"end":375},"obj":"VB"},{"id":"EnjuParser_T58","span":{"begin":376,"end":379},"obj":"DT"},{"id":"EnjuParser_T59","span":{"begin":380,"end":387},"obj":"VBN"},{"id":"EnjuParser_T60","span":{"begin":388,"end":391},"obj":"NN"},{"id":"EnjuParser_T61","span":{"begin":392,"end":403},"obj":"NN"},{"id":"EnjuParser_T62","span":{"begin":404,"end":413},"obj":"NN"}],"relations":[{"id":"EnjuParser_R0","pred":"arg1Of","subj":"EnjuParser_T3","obj":"EnjuParser_T0"},{"id":"EnjuParser_R1","pred":"arg1Of","subj":"EnjuParser_T2","obj":"EnjuParser_T1"},{"id":"EnjuParser_R2","pred":"arg1Of","subj":"EnjuParser_T3","obj":"EnjuParser_T2"},{"id":"EnjuParser_R3","pred":"arg1Of","subj":"EnjuParser_T3","obj":"EnjuParser_T4"},{"id":"EnjuParser_R4","pred":"arg2Of","subj":"EnjuParser_T7","obj":"EnjuParser_T4"},{"id":"EnjuParser_R5","pred":"arg1Of","subj":"EnjuParser_T7","obj":"EnjuParser_T5"},{"id":"EnjuParser_R6","pred":"arg1Of","subj":"EnjuParser_T7","obj":"EnjuParser_T6"},{"id":"EnjuParser_R7","pred":"arg1Of","subj":"EnjuParser_T3","obj":"EnjuParser_T8"},{"id":"EnjuParser_R8","pred":"arg2Of","subj":"EnjuParser_T10","obj":"EnjuParser_T8"},{"id":"EnjuParser_R9","pred":"arg1Of","subj":"EnjuParser_T10","obj":"EnjuParser_T9"},{"id":"EnjuParser_R10","pred":"arg1Of","subj":"EnjuParser_T10","obj":"EnjuParser_T11"},{"id":"EnjuParser_R11","pred":"arg2Of","subj":"EnjuParser_T12","obj":"EnjuParser_T11"},{"id":"EnjuParser_R12","pred":"arg1Of","subj":"EnjuParser_T15","obj":"EnjuParser_T13"},{"id":"EnjuParser_R13","pred":"arg1Of","subj":"EnjuParser_T15","obj":"EnjuParser_T14"},{"id":"EnjuParser_R14","pred":"arg1Of","subj":"EnjuParser_T15","obj":"EnjuParser_T16"},{"id":"EnjuParser_R15","pred":"arg2Of","subj":"EnjuParser_T17","obj":"EnjuParser_T16"},{"id":"EnjuParser_R16","pred":"arg1Of","subj":"EnjuParser_T20","obj":"EnjuParser_T17"},{"id":"EnjuParser_R17","pred":"arg2Of","subj":"EnjuParser_T15","obj":"EnjuParser_T17"},{"id":"EnjuParser_R18","pred":"arg2Of","subj":"EnjuParser_T20","obj":"EnjuParser_T18"},{"id":"EnjuParser_R19","pred":"arg1Of","subj":"EnjuParser_T20","obj":"EnjuParser_T19"},{"id":"EnjuParser_R20","pred":"arg1Of","subj":"EnjuParser_T20","obj":"EnjuParser_T21"},{"id":"EnjuParser_R21","pred":"arg2Of","subj":"EnjuParser_T28","obj":"EnjuParser_T21"},{"id":"EnjuParser_R22","pred":"arg1Of","subj":"EnjuParser_T27","obj":"EnjuParser_T22"},{"id":"EnjuParser_R23","pred":"arg1Of","subj":"EnjuParser_T27","obj":"EnjuParser_T23"},{"id":"EnjuParser_R24","pred":"arg2Of","subj":"EnjuParser_T24","obj":"EnjuParser_T23"},{"id":"EnjuParser_R25","pred":"arg3Of","subj":"EnjuParser_T25","obj":"EnjuParser_T23"},{"id":"EnjuParser_R26","pred":"arg1Of","subj":"EnjuParser_T27","obj":"EnjuParser_T26"},{"id":"EnjuParser_R27","pred":"arg1Of","subj":"EnjuParser_T27","obj":"EnjuParser_T28"},{"id":"EnjuParser_R28","pred":"arg2Of","subj":"EnjuParser_T34","obj":"EnjuParser_T28"},{"id":"EnjuParser_R29","pred":"arg1Of","subj":"EnjuParser_T34","obj":"EnjuParser_T29"},{"id":"EnjuParser_R30","pred":"arg1Of","subj":"EnjuParser_T34","obj":"EnjuParser_T30"},{"id":"EnjuParser_R31","pred":"arg2Of","subj":"EnjuParser_T31","obj":"EnjuParser_T30"},{"id":"EnjuParser_R32","pred":"arg3Of","subj":"EnjuParser_T32","obj":"EnjuParser_T30"},{"id":"EnjuParser_R33","pred":"arg1Of","subj":"EnjuParser_T34","obj":"EnjuParser_T33"},{"id":"EnjuParser_R34","pred":"arg1Of","subj":"EnjuParser_T17","obj":"EnjuParser_T35"},{"id":"EnjuParser_R35","pred":"arg2Of","subj":"EnjuParser_T39","obj":"EnjuParser_T35"},{"id":"EnjuParser_R36","pred":"arg1Of","subj":"EnjuParser_T39","obj":"EnjuParser_T36"},{"id":"EnjuParser_R37","pred":"arg1Of","subj":"EnjuParser_T38","obj":"EnjuParser_T37"},{"id":"EnjuParser_R38","pred":"arg1Of","subj":"EnjuParser_T39","obj":"EnjuParser_T38"},{"id":"EnjuParser_R39","pred":"arg1Of","subj":"EnjuParser_T50","obj":"EnjuParser_T40"},{"id":"EnjuParser_R40","pred":"arg2Of","subj":"EnjuParser_T41","obj":"EnjuParser_T40"},{"id":"EnjuParser_R41","pred":"arg1Of","subj":"EnjuParser_T41","obj":"EnjuParser_T42"},{"id":"EnjuParser_R42","pred":"arg2Of","subj":"EnjuParser_T43","obj":"EnjuParser_T42"},{"id":"EnjuParser_R43","pred":"arg1Of","subj":"EnjuParser_T41","obj":"EnjuParser_T44"},{"id":"EnjuParser_R44","pred":"arg2Of","subj":"EnjuParser_T46","obj":"EnjuParser_T44"},{"id":"EnjuParser_R45","pred":"arg1Of","subj":"EnjuParser_T46","obj":"EnjuParser_T45"},{"id":"EnjuParser_R46","pred":"arg1Of","subj":"EnjuParser_T50","obj":"EnjuParser_T47"},{"id":"EnjuParser_R47","pred":"arg1Of","subj":"EnjuParser_T48","obj":"EnjuParser_T49"},{"id":"EnjuParser_R48","pred":"arg2Of","subj":"EnjuParser_T50","obj":"EnjuParser_T49"},{"id":"EnjuParser_R49","pred":"arg2Of","subj":"EnjuParser_T48","obj":"EnjuParser_T50"},{"id":"EnjuParser_R50","pred":"arg1Of","subj":"EnjuParser_T50","obj":"EnjuParser_T51"},{"id":"EnjuParser_R51","pred":"arg2Of","subj":"EnjuParser_T55","obj":"EnjuParser_T51"},{"id":"EnjuParser_R52","pred":"arg1Of","subj":"EnjuParser_T55","obj":"EnjuParser_T52"},{"id":"EnjuParser_R53","pred":"arg1Of","subj":"EnjuParser_T55","obj":"EnjuParser_T53"},{"id":"EnjuParser_R54","pred":"arg1Of","subj":"EnjuParser_T55","obj":"EnjuParser_T54"},{"id":"EnjuParser_R55","pred":"arg1Of","subj":"EnjuParser_T57","obj":"EnjuParser_T56"},{"id":"EnjuParser_R56","pred":"modOf","subj":"EnjuParser_T50","obj":"EnjuParser_T56"},{"id":"EnjuParser_R57","pred":"arg2Of","subj":"EnjuParser_T62","obj":"EnjuParser_T57"},{"id":"EnjuParser_R58","pred":"arg1Of","subj":"EnjuParser_T62","obj":"EnjuParser_T58"},{"id":"EnjuParser_R59","pred":"arg2Of","subj":"EnjuParser_T62","obj":"EnjuParser_T59"},{"id":"EnjuParser_R60","pred":"arg1Of","subj":"EnjuParser_T62","obj":"EnjuParser_T60"},{"id":"EnjuParser_R61","pred":"arg1Of","subj":"EnjuParser_T62","obj":"EnjuParser_T61"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos600-FMA","denotations":[{"id":"T1","span":{"begin":360,"end":367},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"Glycan"},{"id":"T2","span":{"begin":93,"end":96},"obj":"Glycan"},{"id":"T3","span":{"begin":388,"end":391},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A4","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A2","pred":"glycosmos_id","subj":"T2","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A5","pred":"image","subj":"T2","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A3","pred":"glycosmos_id","subj":"T3","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A6","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T2","span":{"begin":93,"end":96},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T3","span":{"begin":388,"end":391},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"}],"attributes":[{"id":"A1","pred":"glycoepitope_id","subj":"T1","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A2","pred":"glycoepitope_id","subj":"T2","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A3","pred":"glycoepitope_id","subj":"T3","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":93,"end":247},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":248,"end":414},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"T2","span":{"begin":93,"end":247},"obj":"Sentence"},{"id":"T3","span":{"begin":248,"end":414},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"T2","span":{"begin":93,"end":247},"obj":"Sentence"},{"id":"T3","span":{"begin":248,"end":414},"obj":"Sentence"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"Glycan"},{"id":"T2","span":{"begin":93,"end":96},"obj":"Glycan"},{"id":"T3","span":{"begin":388,"end":391},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A4","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A2","pred":"glycosmos_id","subj":"T2","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A5","pred":"image","subj":"T2","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A3","pred":"glycosmos_id","subj":"T3","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A6","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}

{"project":"GlyCosmos15-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":35,"end":38},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T2","span":{"begin":93,"end":96},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T3","span":{"begin":388,"end":391},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"}],"attributes":[{"id":"A1","pred":"glycoepitope_id","subj":"T1","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A2","pred":"glycoepitope_id","subj":"T2","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A3","pred":"glycoepitope_id","subj":"T3","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.\nGM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate."}