| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T21 |
4-13 |
Regulation |
denotes |
Regulates |
| T11 |
14-18 |
Protein |
denotes |
TNFα |
| T12 |
43-47 |
Protein |
denotes |
RIP1 |
| T13 |
443-473 |
Protein |
denotes |
receptor interacting protein-1 |
| T14 |
475-479 |
Protein |
denotes |
RIP1 |
| T22 |
580-584 |
Regulation |
denotes |
role |
| T15 |
588-592 |
Protein |
denotes |
TNFα |
| T23 |
593-603 |
Gene_expression |
denotes |
production |
| T24 |
632-641 |
Positive_regulation |
denotes |
activated |
| T16 |
647-651 |
Protein |
denotes |
RIP1 |
| T25 |
652-661 |
Regulation |
denotes |
dependent |
| T26 |
682-697 |
Phosphorylation |
denotes |
phosphorylation |
| T17 |
807-811 |
Protein |
denotes |
RIP1 |
| T18 |
973-977 |
Protein |
denotes |
RIP1 |
| T27 |
1010-1020 |
Gene_expression |
denotes |
production |
| T19 |
1024-1028 |
Protein |
denotes |
TNFα |
| T20 |
1149-1153 |
Protein |
denotes |
TNFα |
| T28 |
1154-1164 |
Gene_expression |
denotes |
production |
| T795 |
2132-2136 |
Protein |
denotes |
RIP1 |
| T796 |
2141-2145 |
Protein |
denotes |
RIP3 |
| T797 |
2757-2761 |
Protein |
denotes |
RIP1 |
| T798 |
2766-2770 |
Protein |
denotes |
RIP3 |
| T799 |
2964-2968 |
Protein |
denotes |
RIP1 |
| T800 |
3015-3020 |
Protein |
denotes |
c-Jun |
| T801 |
3180-3184 |
Protein |
denotes |
TNFα |
| T5056 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T802 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T803 |
3352-3356 |
Protein |
denotes |
TNFα |
| T814 |
3357-3367 |
Gene_expression |
denotes |
production |
| T804 |
3627-3634 |
Protein |
denotes |
insulin |
| T815 |
3635-3644 |
Regulation |
denotes |
dependent |
| T816 |
3645-3655 |
Positive_regulation |
denotes |
activation |
| T805 |
4106-4113 |
Protein |
denotes |
insulin |
| T817 |
4204-4214 |
Positive_regulation |
denotes |
activation |
| T806 |
4284-4288 |
Protein |
denotes |
RIP1 |
| T807 |
4472-4476 |
Protein |
denotes |
RIP1 |
| T818 |
4532-4541 |
Positive_regulation |
denotes |
activated |
| T13468 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T808 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T13517 |
4562-4571 |
Regulation |
denotes |
dependent |
| T819 |
4562-4571 |
Regulation |
denotes |
dependent |
| T13518 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T820 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T809 |
4709-4711 |
Protein |
denotes |
S6 |
| T821 |
4712-4723 |
Positive_regulation |
denotes |
contributes |
| T822 |
4731-4741 |
Positive_regulation |
denotes |
activation |
| T810 |
4761-4765 |
Protein |
denotes |
TNFα |
| T823 |
4766-4776 |
Gene_expression |
denotes |
production |
| T811 |
4842-4846 |
Protein |
denotes |
RIP1 |
| T812 |
4955-4959 |
Protein |
denotes |
FADD |
| T824 |
5068-5072 |
Regulation |
denotes |
link |
| T813 |
5076-5080 |
Protein |
denotes |
TNFα |
| T825 |
5081-5091 |
Gene_expression |
denotes |
production |
| T2857 |
5289-5319 |
Protein |
denotes |
Basic Fibroblast Growth Factor |
| T2858 |
5472-5476 |
Protein |
denotes |
TNFα |
| T2859 |
5516-5525 |
Protein |
denotes |
caspase-8 |
| T2860 |
5987-5996 |
Protein |
denotes |
caspase-8 |
| T2861 |
6001-6005 |
Protein |
denotes |
FADD |
| T2886 |
6130-6137 |
Positive_regulation |
denotes |
induced |
| T2862 |
6411-6420 |
Protein |
denotes |
caspase-8 |
| T2863 |
6461-6465 |
Protein |
denotes |
RIP1 |
| T2864 |
6481-6500 |
Protein |
denotes |
RIP1 deubiquitinase |
| T2865 |
6501-6505 |
Protein |
denotes |
CYLD |
| T2866 |
6726-6730 |
Protein |
denotes |
bFGF |
| T2867 |
6920-6924 |
Protein |
denotes |
bFGF |
| T2868 |
6929-6934 |
Protein |
denotes |
IGF-1 |
| T2869 |
6944-6947 |
Protein |
denotes |
EGF |
| T2870 |
7081-7085 |
Protein |
denotes |
bFGF |
| T2871 |
7142-7146 |
Protein |
denotes |
TNFα |
| T2872 |
7278-7282 |
Protein |
denotes |
TNFα |
| T28485 |
7377-7381 |
Protein |
denotes |
bFGF |
| T28486 |
7386-7391 |
Protein |
denotes |
IGF-1 |
| T28487 |
7471-7475 |
Protein |
denotes |
TNFα |
| T28489 |
8057-8064 |
Positive_regulation |
denotes |
induced |
| T28488 |
8080-8084 |
Protein |
denotes |
TNFα |
| T2887 |
8294-8303 |
Negative_regulation |
denotes |
inhibitor |
| T2873 |
8307-8311 |
Protein |
denotes |
RIP1 |
| T2874 |
8606-8610 |
Protein |
denotes |
TNFα |
| T2888 |
8611-8618 |
Positive_regulation |
denotes |
induced |
| T2875 |
8707-8711 |
Protein |
denotes |
RIP1 |
| T2876 |
8853-8857 |
Protein |
denotes |
RIP1 |
| T2877 |
8992-8996 |
Protein |
denotes |
TNFα |
| T2878 |
9046-9050 |
Protein |
denotes |
bFGF |
| T2879 |
9091-9095 |
Protein |
denotes |
RIP1 |
| T2880 |
9217-9221 |
Protein |
denotes |
bFGF |
| T2889 |
9246-9253 |
Positive_regulation |
denotes |
induced |
| T2881 |
9319-9348 |
Protein |
denotes |
bFGF receptor tyrosine kinase |
| T2882 |
9419-9423 |
Protein |
denotes |
bFGF |
| T2890 |
9462-9469 |
Positive_regulation |
denotes |
induced |
| T2883 |
9544-9557 |
Protein |
denotes |
bFGF receptor |
| T2891 |
9558-9567 |
Negative_regulation |
denotes |
inhibitor |
| T2884 |
9590-9594 |
Protein |
denotes |
TNFα |
| T2892 |
9595-9602 |
Positive_regulation |
denotes |
induced |
| T2893 |
9780-9788 |
Positive_regulation |
denotes |
promoted |
| T2885 |
9792-9796 |
Protein |
denotes |
bFGF |
| T5090 |
10117-10126 |
Regulation |
denotes |
dependent |
| T5091 |
10127-10137 |
Positive_regulation |
denotes |
Activation |
| T5092 |
10361-10370 |
Positive_regulation |
denotes |
activated |
| T5093 |
10371-10380 |
Positive_regulation |
denotes |
following |
| T5094 |
10426-10436 |
Negative_regulation |
denotes |
Inhibition |
| T5095 |
10449-10458 |
Negative_regulation |
denotes |
inhibitor |
| T5057 |
10595-10599 |
Protein |
denotes |
bFGF |
| T5058 |
10603-10608 |
Protein |
denotes |
IGF-1 |
| T5096 |
10657-10667 |
Negative_regulation |
denotes |
Inhibition |
| T5059 |
10750-10754 |
Protein |
denotes |
TNFα |
| T5060 |
10870-10874 |
Protein |
denotes |
TNFα |
| T5097 |
10939-10949 |
Negative_regulation |
denotes |
inhibition |
| T5061 |
11088-11092 |
Protein |
denotes |
TNFα |
| T5098 |
11093-11100 |
Positive_regulation |
denotes |
induced |
| T28923 |
11193-11200 |
Positive_regulation |
denotes |
induced |
| T28917 |
11217-11221 |
Protein |
denotes |
TNFα |
| T28924 |
11245-11252 |
Positive_regulation |
denotes |
induced |
| T28918 |
11268-11272 |
Protein |
denotes |
TNFα |
| T28925 |
11351-11361 |
Negative_regulation |
denotes |
inhibitors |
| T28926 |
11374-11383 |
Negative_regulation |
denotes |
inhibitor |
| T28919 |
11516-11520 |
Protein |
denotes |
Akt1 |
| T28920 |
11522-11526 |
Protein |
denotes |
Akt2 |
| T28921 |
11532-11543 |
Protein |
denotes |
Akt3 siRNAs |
| T28922 |
11585-11589 |
Protein |
denotes |
TNFα |
| T28927 |
11624-11634 |
Gene_expression |
denotes |
expression |
| T5099 |
11829-11839 |
Negative_regulation |
denotes |
inhibitors |
| T5100 |
11935-11941 |
Negative_regulation |
denotes |
blocks |
| T5101 |
11951-11964 |
Localization |
denotes |
translocation |
| T5102 |
12035-12044 |
Negative_regulation |
denotes |
knockdown |
| T5062 |
12061-12065 |
Protein |
denotes |
Akt1 |
| T5063 |
12070-12074 |
Protein |
denotes |
Akt2 |
| T5103 |
12121-12128 |
Positive_regulation |
denotes |
induced |
| T5064 |
12150-12154 |
Protein |
denotes |
TNFα |
| T5104 |
12169-12179 |
Gene_expression |
denotes |
expression |
| T5065 |
12183-12187 |
Protein |
denotes |
Akt3 |
| T5066 |
12241-12251 |
Protein |
denotes |
Akt3 siRNA |
| T5105 |
12356-12363 |
Positive_regulation |
denotes |
induced |
| T5106 |
12417-12427 |
Positive_regulation |
denotes |
activation |
| T5107 |
12489-12496 |
Regulation |
denotes |
changes |
| T5108 |
12512-12527 |
Phosphorylation |
denotes |
phosphorylation |
| T5067 |
12555-12559 |
Protein |
denotes |
TNFα |
| T5068 |
12725-12729 |
Protein |
denotes |
TNFα |
| T5109 |
12751-12759 |
Positive_regulation |
denotes |
increase |
| T5110 |
12767-12782 |
Phosphorylation |
denotes |
phosphorylation |
| T5111 |
12881-12896 |
Phosphorylation |
denotes |
phosphorylation |
| T5112 |
12897-12904 |
Regulation |
denotes |
changes |
| T5113 |
12977-12985 |
Positive_regulation |
denotes |
increase |
| T5114 |
12993-13008 |
Phosphorylation |
denotes |
phosphorylation |
| T5069 |
13021-13024 |
Protein |
denotes |
p46 |
| T5070 |
13029-13032 |
Protein |
denotes |
p54 |
| T5071 |
13073-13078 |
Protein |
denotes |
c-Jun |
| T29382 |
13220-13224 |
Protein |
denotes |
RIP1 |
| T29387 |
13232-13241 |
Regulation |
denotes |
dependent |
| T29388 |
13242-13257 |
Phosphorylation |
denotes |
phosphorylation |
| T29383 |
13338-13342 |
Protein |
denotes |
TNFα |
| T29384 |
13460-13464 |
Protein |
denotes |
bFGF |
| T29385 |
13624-13628 |
Protein |
denotes |
bFGF |
| T29386 |
13632-13636 |
Protein |
denotes |
bFGF |
| T5072 |
13745-13749 |
Protein |
denotes |
RIP1 |
| T5115 |
13757-13766 |
Negative_regulation |
denotes |
inhibitor |
| T5116 |
13786-13795 |
Negative_regulation |
denotes |
prevented |
| T5117 |
13800-13808 |
Positive_regulation |
denotes |
increase |
| T5073 |
13819-13822 |
Protein |
denotes |
Akt |
| T5118 |
13823-13838 |
Phosphorylation |
denotes |
phosphorylation |
| T5119 |
13988-13995 |
Negative_regulation |
denotes |
reduced |
| T5074 |
14014-14018 |
Protein |
denotes |
TNFα |
| T5075 |
14089-14094 |
Protein |
denotes |
c-Jun |
| T5120 |
14095-14104 |
Positive_regulation |
denotes |
following |
| T5121 |
14175-14183 |
Positive_regulation |
denotes |
increase |
| T5076 |
14187-14192 |
Protein |
denotes |
c-Jun |
| T5122 |
14204-14214 |
Negative_regulation |
denotes |
attenuated |
| T5123 |
14252-14257 |
Regulation |
denotes |
alter |
| T5124 |
14268-14283 |
Phosphorylation |
denotes |
phosphorylation |
| T5125 |
14364-14379 |
Phosphorylation |
denotes |
phosphorylation |
| T5077 |
14402-14406 |
Protein |
denotes |
RIP1 |
| T5126 |
14407-14416 |
Regulation |
denotes |
dependent |
| T5127 |
14456-14471 |
Phosphorylation |
denotes |
phosphorylation |
| T5128 |
14515-14524 |
Positive_regulation |
denotes |
following |
| T5078 |
14698-14702 |
Protein |
denotes |
RIP1 |
| T5129 |
14725-14735 |
Regulation |
denotes |
regulation |
| T5079 |
14869-14873 |
Protein |
denotes |
bFGF |
| T5130 |
14953-14961 |
Positive_regulation |
denotes |
increase |
| T5131 |
14988-15003 |
Phosphorylation |
denotes |
phosphorylation |
| T5080 |
15030-15035 |
Protein |
denotes |
c-Jun |
| T5081 |
15158-15162 |
Protein |
denotes |
bFGF |
| T5082 |
15181-15185 |
Protein |
denotes |
bFGF |
| T5132 |
15198-15204 |
Positive_regulation |
denotes |
caused |
| T5133 |
15231-15239 |
Positive_regulation |
denotes |
increase |
| T5134 |
15247-15262 |
Phosphorylation |
denotes |
phosphorylation |
| T5135 |
15318-15326 |
Positive_regulation |
denotes |
increase |
| T5136 |
15404-15410 |
Regulation |
denotes |
effect |
| T5137 |
15424-15432 |
Positive_regulation |
denotes |
increase |
| T5083 |
15453-15458 |
Protein |
denotes |
c-Jun |
| T5138 |
15459-15474 |
Phosphorylation |
denotes |
phosphorylation |
| T5139 |
15475-15484 |
Positive_regulation |
denotes |
triggered |
| T5084 |
15493-15497 |
Protein |
denotes |
bFGF |
| T5085 |
15502-15506 |
Protein |
denotes |
bFGF |
| T5140 |
15585-15592 |
Negative_regulation |
denotes |
blocked |
| T5086 |
15597-15601 |
Protein |
denotes |
bFGF |
| T5141 |
15607-15615 |
Positive_regulation |
denotes |
increase |
| T5142 |
15670-15680 |
Positive_regulation |
denotes |
activation |
| T5087 |
15741-15745 |
Protein |
denotes |
RIP1 |
| T5143 |
15863-15871 |
Positive_regulation |
denotes |
increase |
| T5144 |
15882-15897 |
Phosphorylation |
denotes |
phosphorylation |
| T5145 |
15956-15964 |
Positive_regulation |
denotes |
increase |
| T5146 |
15968-15983 |
Phosphorylation |
denotes |
phosphorylation |
| T5147 |
16051-16066 |
Phosphorylation |
denotes |
phosphorylation |
| T5088 |
16165-16169 |
Protein |
denotes |
RIP1 |
| T5148 |
16180-16188 |
Positive_regulation |
denotes |
increase |
| T5149 |
16203-16218 |
Phosphorylation |
denotes |
phosphorylation |
| T5150 |
16299-16308 |
Positive_regulation |
denotes |
increases |
| T5151 |
16324-16339 |
Phosphorylation |
denotes |
phosphorylation |
| T5089 |
16449-16453 |
Protein |
denotes |
RIP1 |
| T7355 |
16463-16467 |
Protein |
denotes |
TNFα |
| T7366 |
16468-16475 |
Positive_regulation |
denotes |
Induces |
| T7367 |
16476-16483 |
Positive_regulation |
denotes |
Delayed |
| T7368 |
16495-16510 |
Phosphorylation |
denotes |
Phosphorylation |
| T7356 |
16584-16588 |
Protein |
denotes |
TNFα |
| T7369 |
16677-16686 |
Negative_regulation |
denotes |
attenuate |
| T7357 |
16687-16691 |
Protein |
denotes |
TNFα |
| T7370 |
16700-16707 |
Regulation |
denotes |
changes |
| T7371 |
16722-16737 |
Phosphorylation |
denotes |
phosphorylation |
| T7358 |
16843-16847 |
Protein |
denotes |
TNFα |
| T7372 |
16871-16881 |
Positive_regulation |
denotes |
activation |
| T7359 |
16976-16980 |
Protein |
denotes |
TNFα |
| T7373 |
17022-17033 |
Regulation |
denotes |
independent |
| T7360 |
17069-17073 |
Protein |
denotes |
TNFα |
| T7361 |
17133-17137 |
Protein |
denotes |
TNFα |
| T7374 |
17175-17183 |
Positive_regulation |
denotes |
increase |
| T7375 |
17191-17206 |
Phosphorylation |
denotes |
phosphorylation |
| T7362 |
17218-17223 |
Protein |
denotes |
c-Jun |
| T7376 |
17279-17286 |
Negative_regulation |
denotes |
reduced |
| T7363 |
17377-17381 |
Protein |
denotes |
RIP1 |
| T7364 |
17476-17480 |
Protein |
denotes |
Ask1 |
| T7365 |
17517-17521 |
Protein |
denotes |
RIP1 |
| T8099 |
17568-17576 |
Positive_regulation |
denotes |
Increase |
| T8100 |
17591-17606 |
Phosphorylation |
denotes |
Phosphorylation |
| T8094 |
17698-17702 |
Protein |
denotes |
RIP1 |
| T8101 |
17720-17728 |
Positive_regulation |
denotes |
increase |
| T8102 |
17743-17758 |
Phosphorylation |
denotes |
phosphorylation |
| T8103 |
17865-17871 |
Positive_regulation |
denotes |
induce |
| T8104 |
18051-18066 |
Phosphorylation |
denotes |
phosphorylation |
| T8105 |
18141-18150 |
Negative_regulation |
denotes |
inhibitor |
| T8095 |
18244-18248 |
Protein |
denotes |
TNFα |
| T8096 |
18252-18256 |
Protein |
denotes |
bFGF |
| T8106 |
18418-18433 |
Phosphorylation |
denotes |
phosphorylation |
| T8097 |
18462-18466 |
Protein |
denotes |
bFGF |
| T8098 |
18501-18505 |
Protein |
denotes |
bFGF |
| T8107 |
18571-18581 |
Positive_regulation |
denotes |
activation |
| T8108 |
18690-18699 |
Negative_regulation |
denotes |
prevented |
| T8109 |
18787-18797 |
Positive_regulation |
denotes |
activation |
| T8110 |
18881-18885 |
Regulation |
denotes |
role |
| T8111 |
18902-18912 |
Positive_regulation |
denotes |
activation |
| T29736 |
19020-19035 |
Phosphorylation |
denotes |
phosphorylation |
| T29731 |
19117-19121 |
Protein |
denotes |
bFGF |
| T29732 |
19237-19241 |
Protein |
denotes |
TNFα |
| T29733 |
19249-19253 |
Protein |
denotes |
bFGF |
| T29734 |
19503-19507 |
Protein |
denotes |
bFGF |
| T29735 |
19738-19742 |
Protein |
denotes |
bFGF |
| T8925 |
19961-19969 |
Positive_regulation |
denotes |
increase |
| T8926 |
19980-19995 |
Phosphorylation |
denotes |
phosphorylation |
| T8927 |
20088-20096 |
Positive_regulation |
denotes |
increase |
| T8928 |
20104-20119 |
Phosphorylation |
denotes |
phosphorylation |
| T8883 |
20216-20231 |
Protein |
denotes |
double minute 2 |
| T8884 |
20233-20237 |
Protein |
denotes |
MDM2 |
| T8885 |
20273-20304 |
Protein |
denotes |
p70 ribosomal protein S6 Kinase |
| T8886 |
20306-20312 |
Protein |
denotes |
p70S6K |
| T8887 |
20315-20317 |
Protein |
denotes |
S6 |
| T8888 |
20345-20350 |
Protein |
denotes |
FoxO1 |
| T8889 |
20352-20357 |
Protein |
denotes |
FoxO4 |
| T8890 |
20359-20363 |
Protein |
denotes |
MDM2 |
| T8891 |
20414-20420 |
Protein |
denotes |
FoxO3a |
| T8892 |
20422-20428 |
Protein |
denotes |
GSK-3α |
| T8893 |
20429-20430 |
Protein |
denotes |
β |
| T8894 |
20432-20438 |
Protein |
denotes |
p70S6K |
| T8895 |
20457-20459 |
Protein |
denotes |
S6 |
| T8929 |
20563-20571 |
Positive_regulation |
denotes |
increase |
| T8930 |
20579-20594 |
Phosphorylation |
denotes |
phosphorylation |
| T8896 |
20629-20635 |
Protein |
denotes |
pFoxO1 |
| T8931 |
20896-20905 |
Positive_regulation |
denotes |
increases |
| T8932 |
20929-20938 |
Negative_regulation |
denotes |
abrogated |
| T8897 |
21124-21128 |
Protein |
denotes |
RIP1 |
| T30214 |
21290-21294 |
Protein |
denotes |
TNFα |
| T30215 |
21390-21394 |
Protein |
denotes |
bFGF |
| T30216 |
21398-21402 |
Protein |
denotes |
bFGF |
| T30217 |
21551-21555 |
Protein |
denotes |
TNFα |
| T30219 |
21588-21598 |
Negative_regulation |
denotes |
inhibitors |
| T30220 |
21694-21703 |
Negative_regulation |
denotes |
knockdown |
| T30218 |
21764-21768 |
Protein |
denotes |
TNFα |
| T8933 |
22171-22181 |
Negative_regulation |
denotes |
inhibition |
| T8934 |
22209-22218 |
Negative_regulation |
denotes |
inhibitor |
| T8898 |
22241-22247 |
Protein |
denotes |
Raptor |
| T8935 |
22377-22386 |
Negative_regulation |
denotes |
inhibitor |
| T8936 |
22416-22425 |
Negative_regulation |
denotes |
inhibited |
| T8937 |
22449-22458 |
Negative_regulation |
denotes |
Knockdown |
| T8899 |
22616-22620 |
Protein |
denotes |
TNFα |
| T8900 |
22697-22709 |
Protein |
denotes |
p70S6 kinase |
| T8901 |
22747-22749 |
Protein |
denotes |
S6 |
| T8902 |
22925-22931 |
Protein |
denotes |
p70S6K |
| T8938 |
23005-23010 |
Negative_regulation |
denotes |
block |
| T8903 |
23011-23013 |
Protein |
denotes |
S6 |
| T8939 |
23014-23029 |
Phosphorylation |
denotes |
phosphorylation |
| T8940 |
23059-23068 |
Negative_regulation |
denotes |
knockdown |
| T8904 |
23072-23074 |
Protein |
denotes |
S6 |
| T8941 |
23083-23093 |
Negative_regulation |
denotes |
attenuated |
| T8905 |
23167-23173 |
Protein |
denotes |
p70S6K |
| T8906 |
23174-23176 |
Protein |
denotes |
S6 |
| T8942 |
23251-23258 |
Binding |
denotes |
targets |
| T8907 |
23422-23426 |
Protein |
denotes |
RIP1 |
| T8943 |
23467-23479 |
Positive_regulation |
denotes |
upregulation |
| T8908 |
23483-23487 |
Protein |
denotes |
TNFα |
| T8944 |
23635-23644 |
Positive_regulation |
denotes |
increased |
| T8945 |
23645-23654 |
Gene_expression |
denotes |
synthesis |
| T8909 |
23658-23662 |
Protein |
denotes |
TNFα |
| T8946 |
23747-23757 |
Positive_regulation |
denotes |
contribute |
| T8910 |
23761-23765 |
Protein |
denotes |
TNFα |
| T8911 |
23795-23799 |
Protein |
denotes |
RIP1 |
| T8947 |
23810-23818 |
Positive_regulation |
denotes |
increase |
| T8912 |
23822-23826 |
Protein |
denotes |
TNFα |
| T8913 |
23864-23868 |
Protein |
denotes |
TNFα |
| T8948 |
23881-23890 |
Positive_regulation |
denotes |
increased |
| T8914 |
23929-23933 |
Protein |
denotes |
RIP1 |
| T8915 |
23974-23978 |
Protein |
denotes |
bFGF |
| T8949 |
23985-23994 |
Positive_regulation |
denotes |
triggered |
| T8950 |
24000-24009 |
Positive_regulation |
denotes |
induction |
| T8916 |
24013-24017 |
Protein |
denotes |
TNFα |
| T8951 |
24113-24121 |
Positive_regulation |
denotes |
increase |
| T8952 |
24150-24156 |
Positive_regulation |
denotes |
caused |
| T8953 |
24166-24178 |
Positive_regulation |
denotes |
upregulation |
| T8917 |
24182-24186 |
Protein |
denotes |
TNFα |
| T8954 |
24215-24224 |
Positive_regulation |
denotes |
increased |
| T8918 |
24371-24375 |
Protein |
denotes |
TNFα |
| T30643 |
24464-24468 |
Protein |
denotes |
TNFα |
| T30644 |
24574-24578 |
Protein |
denotes |
bFGF |
| T30645 |
24654-24659 |
Protein |
denotes |
mTNFα |
| T30646 |
24690-24693 |
Protein |
denotes |
18S |
| T30647 |
24742-24746 |
Protein |
denotes |
TNFα |
| T30648 |
24848-24852 |
Protein |
denotes |
TNFα |
| T30651 |
24894-24903 |
Negative_regulation |
denotes |
knockdown |
| T30649 |
24973-24977 |
Protein |
denotes |
TNFα |
| T30650 |
25020-25025 |
Protein |
denotes |
mTNFα |
| T8955 |
25146-25156 |
Positive_regulation |
denotes |
contribute |
| T8956 |
25164-25176 |
Positive_regulation |
denotes |
upregulation |
| T8919 |
25180-25184 |
Protein |
denotes |
TNFα |
| T8957 |
25247-25252 |
Negative_regulation |
denotes |
siRNA |
| T8958 |
25253-25262 |
Negative_regulation |
denotes |
knockdown |
| T8959 |
25279-25286 |
Negative_regulation |
denotes |
reduced |
| T8920 |
25287-25291 |
Protein |
denotes |
TNFα |
| T8921 |
25349-25353 |
Protein |
denotes |
RIP1 |
| T8960 |
25362-25372 |
Negative_regulation |
denotes |
inhibitors |
| T8961 |
25380-25386 |
Regulation |
denotes |
effect |
| T8922 |
25404-25408 |
Protein |
denotes |
TNFα |
| T8962 |
25447-25457 |
Positive_regulation |
denotes |
stimulated |
| T8923 |
25463-25467 |
Protein |
denotes |
bFGF |
| T8963 |
25570-25578 |
Positive_regulation |
denotes |
increase |
| T8924 |
25582-25586 |
Protein |
denotes |
TNFα |
| T11782 |
25702-25706 |
Protein |
denotes |
TNFα |
| T11794 |
25806-25816 |
Negative_regulation |
denotes |
inhibitors |
| T11795 |
25820-25825 |
Negative_regulation |
denotes |
block |
| T11796 |
25830-25838 |
Positive_regulation |
denotes |
increase |
| T11783 |
25842-25846 |
Protein |
denotes |
TNFα |
| T11797 |
25927-25936 |
Negative_regulation |
denotes |
Knockdown |
| T11784 |
25953-25957 |
Protein |
denotes |
Akt1 |
| T11785 |
25962-25966 |
Protein |
denotes |
Akt2 |
| T11798 |
25970-25980 |
Negative_regulation |
denotes |
inhibition |
| T11799 |
26000-26010 |
Negative_regulation |
denotes |
suppressed |
| T11800 |
26027-26036 |
Regulation |
denotes |
dependent |
| T11801 |
26037-26045 |
Positive_regulation |
denotes |
increase |
| T11786 |
26057-26062 |
Protein |
denotes |
c-Jun |
| T11802 |
26063-26078 |
Phosphorylation |
denotes |
phosphorylation |
| T11787 |
26143-26147 |
Protein |
denotes |
RIP1 |
| T11803 |
26181-26191 |
Negative_regulation |
denotes |
inhibition |
| T11804 |
26204-26213 |
Negative_regulation |
denotes |
inhibited |
| T11805 |
26246-26254 |
Positive_regulation |
denotes |
increase |
| T11788 |
26258-26262 |
Protein |
denotes |
bFGF |
| T11806 |
26272-26279 |
Positive_regulation |
denotes |
induced |
| T11789 |
26288-26293 |
Protein |
denotes |
c-Jun |
| T11807 |
26294-26309 |
Phosphorylation |
denotes |
phosphorylation |
| T11808 |
26322-26331 |
Negative_regulation |
denotes |
Knockdown |
| T11790 |
26359-26365 |
Protein |
denotes |
p70S6K |
| T11809 |
26392-26402 |
Negative_regulation |
denotes |
attenuated |
| T11810 |
26430-26438 |
Positive_regulation |
denotes |
increase |
| T11791 |
26450-26455 |
Protein |
denotes |
c-Jun |
| T11811 |
26456-26471 |
Phosphorylation |
denotes |
phosphorylation |
| T11792 |
26550-26553 |
Protein |
denotes |
S6K |
| T11793 |
26583-26587 |
Protein |
denotes |
RIP1 |
| T12690 |
26691-26695 |
Protein |
denotes |
PDK1 |
| T12697 |
26708-26716 |
Positive_regulation |
denotes |
Increase |
| T12698 |
26731-26746 |
Phosphorylation |
denotes |
Phosphorylation |
| T12699 |
26784-26794 |
Regulation |
denotes |
regulation |
| T12700 |
26833-26844 |
Binding |
denotes |
recruitment |
| T12701 |
26878-26886 |
Positive_regulation |
denotes |
mediated |
| T12702 |
26894-26901 |
Binding |
denotes |
binding |
| T12703 |
26909-26940 |
Entity |
denotes |
pleckstrin homology (PH) domain |
| T12704 |
27044-27058 |
Phosphorylation |
denotes |
phosphorylated |
| T12691 |
27083-27128 |
Protein |
denotes |
3-phosphoinositide dependent protein kinase-1 |
| T12692 |
27130-27134 |
Protein |
denotes |
PDK1 |
| T12705 |
27225-27240 |
Phosphorylation |
denotes |
phosphorylation |
| T12706 |
27244-27253 |
Positive_regulation |
denotes |
increased |
| T12707 |
27311-27320 |
Regulation |
denotes |
dependent |
| T12693 |
27333-27337 |
Protein |
denotes |
PDK1 |
| T12708 |
27339-27349 |
Negative_regulation |
denotes |
Inhibition |
| T12694 |
27362-27366 |
Protein |
denotes |
PDK1 |
| T12709 |
27421-27429 |
Positive_regulation |
denotes |
resulted |
| T12710 |
27447-27457 |
Negative_regulation |
denotes |
inhibition |
| T12711 |
27487-27502 |
Phosphorylation |
denotes |
phosphorylation |
| T12712 |
27533-27542 |
Negative_regulation |
denotes |
knockdown |
| T12695 |
27546-27550 |
Protein |
denotes |
PDK1 |
| T12713 |
27582-27591 |
Negative_regulation |
denotes |
inhibited |
| T12714 |
27603-27618 |
Phosphorylation |
denotes |
phosphorylation |
| T12696 |
27652-27656 |
Protein |
denotes |
PDK1 |
| T12715 |
27675-27683 |
Positive_regulation |
denotes |
required |
| T12716 |
27706-27716 |
Positive_regulation |
denotes |
activation |
| T13497 |
27738-27748 |
Gene_expression |
denotes |
Expression |
| T13498 |
27853-27863 |
Gene_expression |
denotes |
expressing |
| T13454 |
27896-27900 |
Protein |
denotes |
Akt1 |
| T13455 |
27902-27909 |
Protein |
denotes |
Myr-Akt |
| T13456 |
27948-27953 |
Protein |
denotes |
K179M |
| T13457 |
28024-28028 |
Protein |
denotes |
RIP1 |
| T13499 |
28043-28053 |
Positive_regulation |
denotes |
activation |
| T13458 |
28096-28100 |
Protein |
denotes |
Akt1 |
| T13459 |
28102-28109 |
Protein |
denotes |
Myr-Akt |
| T13500 |
28225-28237 |
Localization |
denotes |
localization |
| T13501 |
28272-28280 |
Negative_regulation |
denotes |
deletion |
| T13502 |
28307-28313 |
Entity |
denotes |
domain |
| T13503 |
28416-28426 |
Gene_expression |
denotes |
expressing |
| T13460 |
28427-28434 |
Protein |
denotes |
Myr-Akt |
| T13461 |
28713-28720 |
Protein |
denotes |
Myr-Akt |
| T13462 |
28734-28739 |
Protein |
denotes |
K179M |
| T13504 |
28772-28779 |
Positive_regulation |
denotes |
induced |
| T13463 |
28826-28833 |
Protein |
denotes |
Myr-Akt |
| T13505 |
28892-28900 |
Positive_regulation |
denotes |
increase |
| T13506 |
28915-28930 |
Phosphorylation |
denotes |
phosphorylation |
| T13507 |
29008-29018 |
Positive_regulation |
denotes |
activation |
| T13464 |
29030-29035 |
Protein |
denotes |
c-Jun |
| T13508 |
29036-29051 |
Phosphorylation |
denotes |
phosphorylation |
| T13509 |
29066-29078 |
Positive_regulation |
denotes |
upregulation |
| T13465 |
29082-29086 |
Protein |
denotes |
TNFα |
| T13510 |
29297-29307 |
Positive_regulation |
denotes |
sufficient |
| T13511 |
29311-29319 |
Negative_regulation |
denotes |
uncouple |
| T13512 |
29324-29334 |
Positive_regulation |
denotes |
activation |
| T13466 |
29384-29388 |
Protein |
denotes |
RIP1 |
| T13513 |
29414-29422 |
Regulation |
denotes |
regulate |
| T13514 |
29427-29437 |
Positive_regulation |
denotes |
activation |
| T13467 |
29493-29497 |
Protein |
denotes |
RIP1 |
| T13515 |
29536-29544 |
Positive_regulation |
denotes |
required |
| T13516 |
29553-29560 |
Regulation |
denotes |
changes |
| T31167 |
29630-29640 |
Gene_expression |
denotes |
expression |
| T31164 |
30397-30401 |
Protein |
denotes |
TNFα |
| T31165 |
30468-30471 |
Protein |
denotes |
18S |
| T31168 |
30494-30504 |
Gene_expression |
denotes |
expressing |
| T31166 |
30699-30703 |
Protein |
denotes |
TNFα |
| T13469 |
30828-30835 |
Protein |
denotes |
Myr-Akt |
| T13519 |
30855-30864 |
Positive_regulation |
denotes |
increased |
| T13470 |
30865-30872 |
Protein |
denotes |
Myr-Akt |
| T13520 |
30922-30937 |
Phosphorylation |
denotes |
Phosphorylation |
| T13521 |
30986-30995 |
Positive_regulation |
denotes |
increased |
| T13522 |
30996-31000 |
Positive_regulation |
denotes |
upon |
| T13523 |
31005-31015 |
Gene_expression |
denotes |
expression |
| T13471 |
31019-31026 |
Protein |
denotes |
Myr-Akt |
| T13472 |
31040-31045 |
Protein |
denotes |
K179M |
| T13524 |
31204-31213 |
Positive_regulation |
denotes |
increased |
| T13473 |
31232-31239 |
Protein |
denotes |
Myr-Akt |
| T13474 |
31268-31274 |
Protein |
denotes |
p70S6K |
| T13475 |
31276-31278 |
Protein |
denotes |
S6 |
| T13476 |
31290-31295 |
Protein |
denotes |
FoxO4 |
| T13525 |
31308-31322 |
Phosphorylation |
denotes |
phosphorylated |
| T13526 |
31375-31390 |
Phosphorylation |
denotes |
phosphorylation |
| T13477 |
31394-31399 |
Protein |
denotes |
FoxO1 |
| T13478 |
31404-31408 |
Protein |
denotes |
MDM2 |
| T13527 |
31427-31436 |
Positive_regulation |
denotes |
increased |
| T13528 |
31501-31516 |
Phosphorylation |
denotes |
phosphorylation |
| T13479 |
31520-31527 |
Protein |
denotes |
Myr-Akt |
| T13480 |
31653-31657 |
Protein |
denotes |
TNFα |
| T13529 |
31697-31706 |
Gene_expression |
denotes |
expressed |
| T13481 |
31707-31714 |
Protein |
denotes |
Myr-Akt |
| T13530 |
31747-31754 |
Regulation |
denotes |
effects |
| T13531 |
31824-31836 |
Localization |
denotes |
localization |
| T13532 |
31885-31892 |
Negative_regulation |
denotes |
lacking |
| T13533 |
31902-31911 |
Entity |
denotes |
PH domain |
| T13534 |
31976-31985 |
Positive_regulation |
denotes |
increased |
| T13535 |
31993-32008 |
Phosphorylation |
denotes |
phosphorylation |
| T13536 |
32009-32018 |
Positive_regulation |
denotes |
following |
| T13537 |
32120-32124 |
Regulation |
denotes |
role |
| T13538 |
32136-32151 |
Phosphorylation |
denotes |
phosphorylation |
| T13539 |
32159-32169 |
Regulation |
denotes |
regulation |
| T13540 |
32237-32246 |
Negative_regulation |
denotes |
mutations |
| T13541 |
32276-32285 |
Negative_regulation |
denotes |
reduction |
| T13482 |
32315-32318 |
Protein |
denotes |
Akt |
| T13483 |
32771-32783 |
Protein |
denotes |
S473D mutant |
| T13542 |
32795-32809 |
Phosphorylation |
denotes |
phosphorylated |
| T13484 |
32896-32901 |
Protein |
denotes |
S473A |
| T13485 |
32963-32968 |
Protein |
denotes |
S473A |
| T13543 |
32998-33012 |
Phosphorylation |
denotes |
phosphorylated |
| T13544 |
33043-33052 |
Negative_regulation |
denotes |
inability |
| T13545 |
33076-33080 |
Entity |
denotes |
site |
| T13546 |
33087-33101 |
Phosphorylation |
denotes |
phosphorylated |
| T13486 |
33133-33137 |
Protein |
denotes |
PDK1 |
| T13547 |
33141-33154 |
Phosphorylation |
denotes |
phosphorylate |
| T13548 |
33271-33286 |
Phosphorylation |
denotes |
phosphorylation |
| T13487 |
33298-33303 |
Protein |
denotes |
c-Jun |
| T13488 |
33309-33313 |
Protein |
denotes |
TNFα |
| T13489 |
33339-33344 |
Protein |
denotes |
T308D |
| T13490 |
33583-33588 |
Protein |
denotes |
T308D |
| T13549 |
33668-33682 |
Phosphorylation |
denotes |
phosphorylated |
| T13491 |
33690-33697 |
Protein |
denotes |
Myr-Akt |
| T13492 |
33742-33747 |
Protein |
denotes |
FoxO1 |
| T13493 |
33749-33754 |
Protein |
denotes |
Foxo4 |
| T13494 |
33756-33760 |
Protein |
denotes |
MDM2 |
| T13495 |
33766-33772 |
Protein |
denotes |
p70S6K |
| T13550 |
33943-33951 |
Positive_regulation |
denotes |
allowing |
| T13551 |
34004-34011 |
Positive_regulation |
denotes |
promote |
| T13496 |
34012-34016 |
Protein |
denotes |
TNFα |
| T16738 |
34073-34081 |
Regulation |
denotes |
Controls |
| T16719 |
34082-34086 |
Protein |
denotes |
TNFα |
| T16739 |
34087-34097 |
Gene_expression |
denotes |
Production |
| T16720 |
34149-34153 |
Protein |
denotes |
RIP1 |
| T16721 |
34303-34343 |
Protein |
denotes |
Fas-associated protein with death domain |
| T16722 |
34345-34349 |
Protein |
denotes |
FADD |
| T16740 |
34351-34360 |
Negative_regulation |
denotes |
deficient |
| T16741 |
34481-34488 |
Positive_regulation |
denotes |
induced |
| T16723 |
34509-34513 |
Protein |
denotes |
TNFα |
| T16724 |
34571-34575 |
Protein |
denotes |
RIP1 |
| T16742 |
34583-34592 |
Regulation |
denotes |
dependent |
| T16743 |
34593-34601 |
Positive_regulation |
denotes |
increase |
| T16744 |
34609-34624 |
Phosphorylation |
denotes |
phosphorylation |
| T16725 |
34718-34722 |
Protein |
denotes |
TNFα |
| T16745 |
34740-34749 |
Positive_regulation |
denotes |
increased |
| T16746 |
34813-34822 |
Negative_regulation |
denotes |
inhibited |
| T16726 |
34831-34835 |
Protein |
denotes |
RIP1 |
| T16747 |
34844-34854 |
Negative_regulation |
denotes |
inhibitors |
| T16748 |
34879-34889 |
Negative_regulation |
denotes |
inhibition |
| T16749 |
34980-34990 |
Regulation |
denotes |
regulation |
| T16727 |
35004-35008 |
Protein |
denotes |
TNFα |
| T16750 |
35117-35127 |
Positive_regulation |
denotes |
activation |
| T16728 |
35131-35135 |
Protein |
denotes |
RIP1 |
| T31808 |
35283-35292 |
Regulation |
denotes |
autocrine |
| T31796 |
35293-35297 |
Protein |
denotes |
TNFα |
| T31809 |
35298-35308 |
Gene_expression |
denotes |
production |
| T31797 |
35333-35337 |
Protein |
denotes |
FADD |
| T31810 |
35338-35347 |
Negative_regulation |
denotes |
deficient |
| T31798 |
35379-35383 |
Protein |
denotes |
TNFα |
| T31799 |
35421-35425 |
Protein |
denotes |
TNFα |
| T31800 |
35476-35479 |
Protein |
denotes |
18S |
| T31801 |
35631-35635 |
Protein |
denotes |
TNFα |
| T31811 |
35698-35702 |
Negative_regulation |
denotes |
null |
| T31812 |
35726-35736 |
Gene_expression |
denotes |
expressing |
| T31802 |
35785-35789 |
Protein |
denotes |
TNFα |
| T31803 |
35817-35821 |
Protein |
denotes |
TNFα |
| T31813 |
35881-35891 |
Gene_expression |
denotes |
expressing |
| T31804 |
35908-35912 |
Protein |
denotes |
Akt1 |
| T31805 |
35916-35920 |
Protein |
denotes |
Akt2 |
| T31806 |
35952-35956 |
Protein |
denotes |
TNFα |
| T31807 |
35984-35988 |
Protein |
denotes |
TNFα |
| T16751 |
36147-36155 |
Negative_regulation |
denotes |
deletion |
| T16729 |
36243-36247 |
Protein |
denotes |
TNFα |
| T16752 |
36262-36272 |
Gene_expression |
denotes |
Expression |
| T16753 |
36326-36334 |
Positive_regulation |
denotes |
restored |
| T16730 |
36335-36339 |
Protein |
denotes |
TNFα |
| T16754 |
36340-36355 |
Transcription |
denotes |
mRNA production |
| T16755 |
36359-36367 |
Positive_regulation |
denotes |
response |
| T16731 |
36371-36375 |
Protein |
denotes |
TNFα |
| T16756 |
36478-36487 |
Negative_regulation |
denotes |
knockdown |
| T16757 |
36511-36521 |
Gene_expression |
denotes |
expressing |
| T16732 |
36533-36537 |
Protein |
denotes |
Akt1 |
| T16733 |
36541-36545 |
Protein |
denotes |
Akt2 |
| T16758 |
36551-36565 |
Phosphorylation |
denotes |
phosphorylated |
| T16759 |
36579-36587 |
Positive_regulation |
denotes |
response |
| T16734 |
36591-36595 |
Protein |
denotes |
TNFα |
| T16735 |
36645-36649 |
Protein |
denotes |
RIP1 |
| T16760 |
36650-36659 |
Regulation |
denotes |
dependent |
| T16736 |
36660-36664 |
Protein |
denotes |
TNFα |
| T16761 |
36670-36682 |
Positive_regulation |
denotes |
upregulation |
| T16762 |
36804-36813 |
Regulation |
denotes |
autocrine |
| T16737 |
36814-36818 |
Protein |
denotes |
TNFα |
| T18154 |
37024-37028 |
Protein |
denotes |
RIP1 |
| T18155 |
37118-37122 |
Protein |
denotes |
RIP1 |
| T18156 |
37374-37378 |
Protein |
denotes |
RIP1 |
| T18180 |
37393-37398 |
Positive_regulation |
denotes |
leads |
| T18181 |
37414-37422 |
Positive_regulation |
denotes |
increase |
| T18182 |
37430-37445 |
Phosphorylation |
denotes |
phosphorylation |
| T18183 |
37529-37544 |
Phosphorylation |
denotes |
phosphorylation |
| T18184 |
37609-37616 |
Positive_regulation |
denotes |
induced |
| T18185 |
37636-37641 |
Positive_regulation |
denotes |
leads |
| T18186 |
37665-37677 |
Localization |
denotes |
localization |
| T18187 |
37686-37696 |
Gene_expression |
denotes |
Expression |
| T18157 |
37750-37757 |
Protein |
denotes |
Myr-Akt |
| T18188 |
37823-37833 |
Gene_expression |
denotes |
expression |
| T18158 |
37837-37844 |
Protein |
denotes |
Myr-Akt |
| T18159 |
37913-37917 |
Protein |
denotes |
RIP1 |
| T18189 |
37944-37952 |
Positive_regulation |
denotes |
required |
| T18190 |
37964-37979 |
Phosphorylation |
denotes |
phosphorylation |
| T18191 |
37987-38001 |
Positive_regulation |
denotes |
in response to |
| T32283 |
38138-38142 |
Protein |
denotes |
RIP1 |
| T32286 |
38207-38222 |
Phosphorylation |
denotes |
phosphorylation |
| T32284 |
38297-38301 |
Protein |
denotes |
RIP1 |
| T32285 |
38355-38359 |
Protein |
denotes |
TNFα |
| T32287 |
38371-38381 |
Positive_regulation |
denotes |
Activation |
| T32288 |
38413-38418 |
Positive_regulation |
denotes |
leads |
| T32289 |
38423-38438 |
Phosphorylation |
denotes |
phosphorylation |
| T18192 |
38566-38576 |
Negative_regulation |
denotes |
inhibitors |
| T18193 |
38578-38587 |
Negative_regulation |
denotes |
knockdown |
| T18194 |
38613-38623 |
Gene_expression |
denotes |
expression |
| T18195 |
38667-38677 |
Positive_regulation |
denotes |
activation |
| T18196 |
38882-38897 |
Phosphorylation |
denotes |
phosphorylation |
| T18197 |
39124-39134 |
Positive_regulation |
denotes |
activation |
| T18160 |
39170-39174 |
Protein |
denotes |
RIP1 |
| T18161 |
39297-39301 |
Protein |
denotes |
TNFα |
| T18198 |
39417-39432 |
Phosphorylation |
denotes |
phosphorylation |
| T18199 |
39569-39578 |
Negative_regulation |
denotes |
inhibited |
| T18162 |
39579-39583 |
Protein |
denotes |
TNFα |
| T18200 |
39584-39594 |
Gene_expression |
denotes |
production |
| T18201 |
39617-39626 |
Negative_regulation |
denotes |
inhibited |
| T18202 |
39657-39672 |
Phosphorylation |
denotes |
phosphorylation |
| T18203 |
39808-39815 |
Negative_regulation |
denotes |
inhibit |
| T18163 |
39820-39833 |
Protein |
denotes |
p110δ subunit |
| T18164 |
39851-39855 |
Protein |
denotes |
PDK1 |
| T18204 |
39901-39908 |
Negative_regulation |
denotes |
inhibit |
| T18205 |
39919-39934 |
Phosphorylation |
denotes |
phosphorylation |
| T18165 |
40119-40123 |
Protein |
denotes |
JNK1 |
| T18166 |
40128-40132 |
Protein |
denotes |
JNK2 |
| T18206 |
40184-40193 |
Negative_regulation |
denotes |
knockdown |
| T18167 |
40197-40201 |
Protein |
denotes |
JNK1 |
| T18168 |
40202-40203 |
Protein |
denotes |
2 |
| T18207 |
40212-40227 |
Phosphorylation |
denotes |
phosphorylation |
| T18208 |
40251-40261 |
Negative_regulation |
denotes |
inhibiting |
| T18209 |
40266-40281 |
Phosphorylation |
denotes |
phosphorylation |
| T18169 |
40285-40290 |
Protein |
denotes |
c-Jun |
| T18210 |
40371-40380 |
Negative_regulation |
denotes |
reduction |
| T18170 |
40384-40388 |
Protein |
denotes |
TNFα |
| T18211 |
40389-40399 |
Gene_expression |
denotes |
production |
| T18171 |
40627-40632 |
Protein |
denotes |
c-Jun |
| T18172 |
40662-40666 |
Protein |
denotes |
TNFα |
| T18173 |
40735-40740 |
Protein |
denotes |
c-Jun |
| T18212 |
40747-40756 |
Negative_regulation |
denotes |
knockdown |
| T18213 |
40802-40817 |
Phosphorylation |
denotes |
phosphorylation |
| T18214 |
40822-40829 |
Negative_regulation |
denotes |
reduced |
| T18215 |
40872-40881 |
Regulation |
denotes |
autocrine |
| T18174 |
40882-40886 |
Protein |
denotes |
TNFα |
| T18175 |
40912-40917 |
Protein |
denotes |
c-Jun |
| T18216 |
40978-40988 |
Positive_regulation |
denotes |
activation |
| T18217 |
41054-41062 |
Positive_regulation |
denotes |
increase |
| T18176 |
41087-41092 |
Protein |
denotes |
c-Jun |
| T18177 |
41140-41144 |
Protein |
denotes |
TNFα |
| T18218 |
41174-41183 |
Regulation |
denotes |
dependent |
| T18178 |
41267-41272 |
Protein |
denotes |
c-Jun |
| T18219 |
41407-41422 |
Phosphorylation |
denotes |
phosphorylation |
| T18179 |
41426-41431 |
Protein |
denotes |
c-Jun |
| T20725 |
41723-41727 |
Protein |
denotes |
RIP1 |
| T20766 |
41792-41800 |
Positive_regulation |
denotes |
increase |
| T20767 |
41808-41823 |
Phosphorylation |
denotes |
phosphorylation |
| T20726 |
41867-41871 |
Protein |
denotes |
RIP1 |
| T20727 |
41994-41998 |
Protein |
denotes |
TNFα |
| T20768 |
42058-42073 |
Phosphorylation |
denotes |
phosphorylation |
| T20769 |
42138-42145 |
Positive_regulation |
denotes |
induced |
| T20770 |
42165-42170 |
Positive_regulation |
denotes |
leads |
| T20771 |
42194-42206 |
Localization |
denotes |
localization |
| T20772 |
42215-42225 |
Gene_expression |
denotes |
Expression |
| T20728 |
42269-42276 |
Protein |
denotes |
Myr-Akt |
| T20773 |
42323-42333 |
Gene_expression |
denotes |
expression |
| T20729 |
42337-42344 |
Protein |
denotes |
Myr-Akt |
| T20730 |
42431-42435 |
Protein |
denotes |
TNFα |
| T20731 |
42457-42461 |
Protein |
denotes |
RIP1 |
| T20774 |
42488-42496 |
Positive_regulation |
denotes |
required |
| T20775 |
42508-42523 |
Phosphorylation |
denotes |
phosphorylation |
| T20776 |
42597-42612 |
Phosphorylation |
denotes |
phosphorylation |
| T20777 |
42962-42972 |
Regulation |
denotes |
regulation |
| T20732 |
43036-43040 |
Protein |
denotes |
RIP1 |
| T20778 |
43041-43050 |
Regulation |
denotes |
dependent |
| T20779 |
43051-43059 |
Positive_regulation |
denotes |
increase |
| T20780 |
43074-43089 |
Phosphorylation |
denotes |
phosphorylation |
| T20733 |
43115-43119 |
Protein |
denotes |
RIP1 |
| T20781 |
43308-43314 |
Regulation |
denotes |
effect |
| T20782 |
43327-43336 |
Negative_regulation |
denotes |
inhibitor |
| T20783 |
43362-43377 |
Phosphorylation |
denotes |
phosphorylation |
| T20784 |
43454-43462 |
Positive_regulation |
denotes |
increase |
| T20734 |
43486-43490 |
Protein |
denotes |
RIP1 |
| T20785 |
43498-43507 |
Regulation |
denotes |
targeting |
| T20735 |
43508-43512 |
Protein |
denotes |
PDK1 |
| T20786 |
43607-43622 |
Phosphorylation |
denotes |
phosphorylation |
| T20736 |
43645-43649 |
Protein |
denotes |
RIP1 |
| T20737 |
43762-43769 |
Protein |
denotes |
Myr-Akt |
| T20787 |
43864-43879 |
Phosphorylation |
denotes |
phosphorylation |
| T20788 |
44068-44083 |
Phosphorylation |
denotes |
phosphorylation |
| T20738 |
44094-44098 |
Protein |
denotes |
RIP1 |
| T20739 |
44257-44261 |
Protein |
denotes |
TNFα |
| T20740 |
44983-44987 |
Protein |
denotes |
TNFα |
| T20741 |
45130-45134 |
Protein |
denotes |
TNFα |
| T20789 |
45435-45445 |
Regulation |
denotes |
regulation |
| T20742 |
45456-45460 |
Protein |
denotes |
RIP1 |
| T20790 |
45529-45536 |
Regulation |
denotes |
targets |
| T20791 |
45617-45624 |
Binding |
denotes |
targets |
| T20743 |
45667-45672 |
Protein |
denotes |
FoxO1 |
| T20744 |
45673-45674 |
Protein |
denotes |
4 |
| T20745 |
45680-45684 |
Protein |
denotes |
MDM2 |
| T20792 |
45737-45747 |
Positive_regulation |
denotes |
activation |
| T20746 |
46185-46189 |
Protein |
denotes |
RIP1 |
| T20793 |
46400-46410 |
Positive_regulation |
denotes |
activation |
| T20794 |
46456-46466 |
Positive_regulation |
denotes |
activation |
| T20747 |
46851-46855 |
Protein |
denotes |
TNFα |
| T20795 |
46968-46975 |
Positive_regulation |
denotes |
induced |
| T20748 |
46979-46983 |
Protein |
denotes |
TNFα |
| T20749 |
47343-47347 |
Protein |
denotes |
RIP1 |
| T20750 |
47593-47597 |
Protein |
denotes |
FADD |
| T20796 |
47598-47607 |
Negative_regulation |
denotes |
deficient |
| T20797 |
47688-47696 |
Positive_regulation |
denotes |
increase |
| T20751 |
47700-47704 |
Protein |
denotes |
TNFα |
| T20798 |
47705-47714 |
Gene_expression |
denotes |
synthesis |
| T20752 |
47861-47865 |
Protein |
denotes |
RIP1 |
| T20799 |
47893-47902 |
Positive_regulation |
denotes |
mediating |
| T20800 |
47907-47917 |
Gene_expression |
denotes |
production |
| T20753 |
47921-47925 |
Protein |
denotes |
TNFα |
| T20801 |
48673-48683 |
Positive_regulation |
denotes |
activation |
| T20754 |
48687-48691 |
Protein |
denotes |
TNFα |
| T20802 |
48692-48701 |
Gene_expression |
denotes |
synthesis |
| T20755 |
48705-48709 |
Protein |
denotes |
RIP1 |
| T20756 |
48949-48953 |
Protein |
denotes |
RIP1 |
| T20757 |
48954-48958 |
Protein |
denotes |
RIP3 |
| T20758 |
48980-48984 |
Protein |
denotes |
FADD |
| T20759 |
48989-48998 |
Protein |
denotes |
caspase-8 |
| T20760 |
49069-49073 |
Protein |
denotes |
TNFα |
| T20803 |
49074-49084 |
Gene_expression |
denotes |
production |
| T20804 |
49213-49222 |
Positive_regulation |
denotes |
increased |
| T20805 |
49223-49233 |
Gene_expression |
denotes |
production |
| T20761 |
49237-49241 |
Protein |
denotes |
TNFα |
| T20762 |
49582-49586 |
Protein |
denotes |
RIP1 |
| T20763 |
49591-49595 |
Protein |
denotes |
RIP3 |
| T20806 |
49642-49649 |
Positive_regulation |
denotes |
induced |
| T20764 |
49672-49676 |
Protein |
denotes |
RIP1 |
| T20765 |
49785-49789 |
Protein |
denotes |
RIP1 |
| T25119 |
50120-50129 |
Negative_regulation |
denotes |
inhibitor |
| T25115 |
50802-50806 |
Protein |
denotes |
TNFα |
| T25116 |
50825-50829 |
Protein |
denotes |
bFGF |
| T25117 |
50842-50845 |
Protein |
denotes |
EGF |
| T25118 |
50882-50887 |
Protein |
denotes |
IGF-1 |
| T25577 |
50989-50997 |
Protein |
denotes |
Myr-Akt1 |
| T25578 |
51056-51069 |
Protein |
denotes |
Myr-Akt1-FLAG |
| T25579 |
51201-51209 |
Protein |
denotes |
Myr-Akt1 |
| T25971 |
52217-52221 |
Protein |
denotes |
TNFα |
| T25972 |
52302-52305 |
Protein |
denotes |
18S |
| T25973 |
52392-52396 |
Protein |
denotes |
TNFα |
| T25974 |
52443-52447 |
Protein |
denotes |
TNFα |
| T25975 |
52493-52496 |
Protein |
denotes |
18S |
| T25976 |
52541-52544 |
Protein |
denotes |
18S |
| T26183 |
52603-52607 |
Protein |
denotes |
FADD |
| T26184 |
52608-52617 |
Negative_regulation |
denotes |
deficient |
| T26699 |
54009-54013 |
Protein |
denotes |
Akt1 |
| T26700 |
54035-54039 |
Protein |
denotes |
Akt2 |
| T26701 |
54061-54065 |
Protein |
denotes |
Akt3 |
| T26702 |
54113-54117 |
Protein |
denotes |
PDK1 |
| T26703 |
54176-54181 |
Protein |
denotes |
Mapk8 |
| T26704 |
54203-54208 |
Protein |
denotes |
Mapk9 |
| T26705 |
54402-54406 |
Protein |
denotes |
TNFα |
| T27053 |
54647-54651 |
Protein |
denotes |
TNFα |
| T27054 |
54806-54810 |
Protein |
denotes |
TNFα |
| T27772 |
56096-56104 |
Protein |
denotes |
Myr-Akt1 |
| T28163 |
57079-57083 |
Protein |
denotes |
TNFα |
| T28164 |
57096-57100 |
Protein |
denotes |
TNFα |
| T28275 |
57427-57434 |
Protein |
denotes |
Myr-Akt |
| T28276 |
57601-57616 |
Phosphorylation |
denotes |
Phosphorylation |
| R1 |
T14 |
T13 |
equivalentTo |
RIP1,receptor interacting protein-1 |
| R11129 |
T16719 |
T16739 |
themeOf |
TNFα,Production |
| R11130 |
T16721 |
T16740 |
themeOf |
Fas-associated protein with death domain,deficient |
| R11131 |
T16722 |
T16721 |
equivalentTo |
FADD,Fas-associated protein with death domain |
| R11132 |
T16723 |
T16741 |
causeOf |
TNFα,induced |
| R11133 |
T16725 |
T16745 |
themeOf |
TNFα,increased |
| R11134 |
T16725 |
T16746 |
themeOf |
TNFα,inhibited |
| R11135 |
T16726 |
T16747 |
themeOf |
RIP1,inhibitors |
| R11136 |
T16728 |
T16750 |
causeOf |
RIP1,activation |
| R11137 |
T16730 |
T16754 |
themeOf |
TNFα,mRNA production |
| R11138 |
T16731 |
T16754 |
themeOf |
TNFα,mRNA production |
| R11139 |
T16732 |
T16757 |
themeOf |
Akt1,expressing |
| R11140 |
T16733 |
T16758 |
themeOf |
Akt2,phosphorylated |
| R11141 |
T16735 |
T16760 |
causeOf |
RIP1,dependent |
| R11142 |
T16736 |
T16761 |
themeOf |
TNFα,upregulation |
| R11143 |
T16739 |
T16738 |
themeOf |
Production,Controls |
| R11144 |
T16743 |
T16742 |
themeOf |
increase,dependent |
| R11145 |
T16744 |
T16743 |
themeOf |
phosphorylation,increase |
| R11146 |
T16747 |
T16746 |
causeOf |
inhibitors,inhibited |
| R11147 |
T16754 |
T16753 |
themeOf |
mRNA production,restored |
| R11148 |
T16761 |
T16760 |
themeOf |
upregulation,dependent |
| R12082 |
T18157 |
T18187 |
themeOf |
Myr-Akt,Expression |
| R12083 |
T18158 |
T18188 |
themeOf |
Myr-Akt,expression |
| R12084 |
T18162 |
T18200 |
themeOf |
TNFα,production |
| R12085 |
T18163 |
T18203 |
themeOf |
p110δ subunit,inhibit |
| R12086 |
T18164 |
T18203 |
themeOf |
PDK1,inhibit |
| R12087 |
T18167 |
T18206 |
themeOf |
JNK1,knockdown |
| R12088 |
T18168 |
T18206 |
themeOf |
2,knockdown |
| R12089 |
T18169 |
T18209 |
themeOf |
c-Jun,phosphorylation |
| R12090 |
T18170 |
T18211 |
themeOf |
TNFα,production |
| R12091 |
T18173 |
T18212 |
themeOf |
c-Jun,knockdown |
| R12092 |
T18175 |
T18215 |
causeOf |
c-Jun,autocrine |
| R12093 |
T18176 |
T18217 |
themeOf |
c-Jun,increase |
| R12094 |
T18179 |
T18219 |
themeOf |
c-Jun,phosphorylation |
| R12095 |
T18181 |
T18180 |
themeOf |
increase,leads |
| R12096 |
T18182 |
T18181 |
themeOf |
phosphorylation,increase |
| R12097 |
T18186 |
T18185 |
themeOf |
localization,leads |
| R12098 |
T18190 |
T18191 |
themeOf |
phosphorylation,in response to |
| R12099 |
T18190 |
T18189 |
themeOf |
phosphorylation,required |
| R12100 |
T18200 |
T18199 |
themeOf |
production,inhibited |
| R12101 |
T18202 |
T18201 |
themeOf |
phosphorylation,inhibited |
| R12102 |
T18205 |
T18204 |
themeOf |
phosphorylation,inhibit |
| R12103 |
T18209 |
T18208 |
themeOf |
phosphorylation,inhibiting |
| R12104 |
T18211 |
T18210 |
themeOf |
production,reduction |
| R12105 |
T18213 |
T18214 |
themeOf |
phosphorylation,reduced |
| R13909 |
T20728 |
T20772 |
themeOf |
Myr-Akt,Expression |
| R13910 |
T20729 |
T20773 |
themeOf |
Myr-Akt,expression |
| R13911 |
T20731 |
T20774 |
causeOf |
RIP1,required |
| R13912 |
T20732 |
T20778 |
causeOf |
RIP1,dependent |
| R13913 |
T20734 |
T20784 |
themeOf |
RIP1,increase |
| R13914 |
T20736 |
T20786 |
causeOf |
RIP1,phosphorylation |
| R13915 |
T20738 |
T20788 |
themeOf |
RIP1,phosphorylation |
| R13916 |
T20742 |
T20789 |
causeOf |
RIP1,regulation |
| R13917 |
T20748 |
T20795 |
causeOf |
TNFα,induced |
| R13918 |
T20750 |
T20796 |
themeOf |
FADD,deficient |
| R13919 |
T20751 |
T20798 |
themeOf |
TNFα,synthesis |
| R13920 |
T20752 |
T20799 |
causeOf |
RIP1,mediating |
| R13921 |
T20753 |
T20800 |
themeOf |
TNFα,production |
| R13922 |
T20754 |
T20802 |
themeOf |
TNFα,synthesis |
| R13923 |
T20760 |
T20803 |
themeOf |
TNFα,production |
| R13924 |
T20761 |
T20805 |
themeOf |
TNFα,production |
| R13925 |
T20767 |
T20766 |
themeOf |
phosphorylation,increase |
| R13926 |
T20771 |
T20770 |
themeOf |
localization,leads |
| R13927 |
T20775 |
T20774 |
themeOf |
phosphorylation,required |
| R13928 |
T20779 |
T20778 |
themeOf |
increase,dependent |
| R13929 |
T20780 |
T20779 |
themeOf |
phosphorylation,increase |
| R13930 |
T20796 |
T20797 |
causeOf |
deficient,increase |
| R13931 |
T20798 |
T20797 |
themeOf |
synthesis,increase |
| R13932 |
T20800 |
T20799 |
themeOf |
production,mediating |
| R13933 |
T20802 |
T20801 |
themeOf |
synthesis,activation |
| R13934 |
T20805 |
T20804 |
themeOf |
production,increased |
| R17901 |
T26183 |
T26184 |
themeOf |
FADD,deficient |
| R19753 |
T28488 |
T28489 |
causeOf |
TNFα,induced |
| R1987 |
T2873 |
T2887 |
themeOf |
RIP1,inhibitor |
| R1988 |
T2874 |
T2888 |
causeOf |
TNFα,induced |
| R1989 |
T2883 |
T2891 |
themeOf |
bFGF receptor,inhibitor |
| R1990 |
T2885 |
T2893 |
causeOf |
bFGF,promoted |
| R2 |
T15 |
T23 |
themeOf |
TNFα,production |
| R20065 |
T28917 |
T28923 |
causeOf |
TNFα,induced |
| R20066 |
T28918 |
T28924 |
causeOf |
TNFα,induced |
| R20360 |
T29388 |
T29387 |
themeOf |
phosphorylation,dependent |
| R21994 |
T31796 |
T31809 |
themeOf |
TNFα,production |
| R21995 |
T31797 |
T31810 |
themeOf |
FADD,deficient |
| R21996 |
T31798 |
T31810 |
themeOf |
TNFα,deficient |
| R21997 |
T31802 |
T31812 |
themeOf |
TNFα,expressing |
| R21998 |
T31804 |
T31813 |
themeOf |
Akt1,expressing |
| R21999 |
T31805 |
T31813 |
themeOf |
Akt2,expressing |
| R22000 |
T31806 |
T31813 |
themeOf |
TNFα,expressing |
| R22001 |
T31809 |
T31808 |
themeOf |
production,autocrine |
| R22253 |
T32289 |
T32288 |
themeOf |
phosphorylation,leads |
| R3 |
T19 |
T27 |
themeOf |
TNFα,production |
| R3496 |
T5062 |
T5102 |
themeOf |
Akt1,knockdown |
| R3497 |
T5063 |
T5102 |
themeOf |
Akt2,knockdown |
| R3498 |
T5064 |
T5103 |
causeOf |
TNFα,induced |
| R3499 |
T5065 |
T5104 |
themeOf |
Akt3,expression |
| R3500 |
T5067 |
T5108 |
themeOf |
TNFα,phosphorylation |
| R3501 |
T5068 |
T5109 |
causeOf |
TNFα,increase |
| R3502 |
T5069 |
T5114 |
themeOf |
p46,phosphorylation |
| R3503 |
T5070 |
T5114 |
themeOf |
p54,phosphorylation |
| R3504 |
T5071 |
T5114 |
themeOf |
c-Jun,phosphorylation |
| R3505 |
T5072 |
T5115 |
themeOf |
RIP1,inhibitor |
| R3506 |
T5073 |
T5118 |
themeOf |
Akt,phosphorylation |
| R3507 |
T5074 |
T5119 |
causeOf |
TNFα,reduced |
| R3508 |
T5076 |
T5121 |
themeOf |
c-Jun,increase |
| R3509 |
T5077 |
T5125 |
themeOf |
RIP1,phosphorylation |
| R3510 |
T5080 |
T5131 |
themeOf |
c-Jun,phosphorylation |
| R3511 |
T5083 |
T5138 |
themeOf |
c-Jun,phosphorylation |
| R3512 |
T5084 |
T5139 |
causeOf |
bFGF,triggered |
| R3513 |
T5085 |
T5139 |
causeOf |
bFGF,triggered |
| R3514 |
T5086 |
T5141 |
themeOf |
bFGF,increase |
| R3515 |
T5088 |
T5148 |
causeOf |
RIP1,increase |
| R3516 |
T5092 |
T5093 |
themeOf |
activated,following |
| R3517 |
T5101 |
T5100 |
themeOf |
translocation,blocks |
| R3518 |
T5102 |
T5103 |
themeOf |
knockdown,induced |
| R3519 |
T5110 |
T5109 |
themeOf |
phosphorylation,increase |
| R3520 |
T5114 |
T5113 |
themeOf |
phosphorylation,increase |
| R3521 |
T5115 |
T5116 |
causeOf |
inhibitor,prevented |
| R3522 |
T5117 |
T5116 |
themeOf |
increase,prevented |
| R3523 |
T5118 |
T5117 |
themeOf |
phosphorylation,increase |
| R3524 |
T5121 |
T5122 |
themeOf |
increase,attenuated |
| R3525 |
T5124 |
T5123 |
themeOf |
phosphorylation,alter |
| R3526 |
T5125 |
T5126 |
themeOf |
phosphorylation,dependent |
| R3527 |
T5127 |
T5128 |
themeOf |
phosphorylation,following |
| R3528 |
T5131 |
T5130 |
themeOf |
phosphorylation,increase |
| R3529 |
T5134 |
T5133 |
themeOf |
phosphorylation,increase |
| R3530 |
T5137 |
T5136 |
themeOf |
increase,effect |
| R3531 |
T5138 |
T5139 |
themeOf |
phosphorylation,triggered |
| R3532 |
T5138 |
T5137 |
themeOf |
phosphorylation,increase |
| R3533 |
T5141 |
T5140 |
themeOf |
increase,blocked |
| R3534 |
T5144 |
T5143 |
themeOf |
phosphorylation,increase |
| R3535 |
T5146 |
T5145 |
themeOf |
phosphorylation,increase |
| R3536 |
T5149 |
T5148 |
themeOf |
phosphorylation,increase |
| R3537 |
T5151 |
T5150 |
themeOf |
phosphorylation,increases |
| R4 |
T20 |
T28 |
themeOf |
TNFα,production |
| R4780 |
T7355 |
T7367 |
causeOf |
TNFα,Delayed |
| R4781 |
T7355 |
T7366 |
causeOf |
TNFα,Induces |
| R4782 |
T7362 |
T7375 |
themeOf |
c-Jun,phosphorylation |
| R4783 |
T7367 |
T7366 |
themeOf |
Delayed,Induces |
| R4784 |
T7368 |
T7367 |
themeOf |
Phosphorylation,Delayed |
| R4785 |
T7370 |
T7369 |
themeOf |
changes,attenuate |
| R4786 |
T7371 |
T7370 |
themeOf |
phosphorylation,changes |
| R4787 |
T7375 |
T7374 |
themeOf |
phosphorylation,increase |
| R496 |
T803 |
T814 |
themeOf |
TNFα,production |
| R497 |
T808 |
T818 |
causeOf |
RIP1,activated |
| R498 |
T810 |
T823 |
themeOf |
TNFα,production |
| R499 |
T813 |
T825 |
themeOf |
TNFα,production |
| R5 |
T23 |
T22 |
themeOf |
production,role |
| R500 |
T816 |
T815 |
themeOf |
activation,dependent |
| R501 |
T820 |
T818 |
causeOf |
phosphorylation,activated |
| R502 |
T822 |
T821 |
themeOf |
activation,contributes |
| R503 |
T823 |
T822 |
themeOf |
production,activation |
| R504 |
T825 |
T824 |
themeOf |
production,link |
| R5252 |
T8100 |
T8099 |
themeOf |
Phosphorylation,Increase |
| R5253 |
T8102 |
T8101 |
themeOf |
phosphorylation,increase |
| R5254 |
T8111 |
T8110 |
themeOf |
activation,role |
| R5799 |
T8883 |
T8928 |
themeOf |
double minute 2,phosphorylation |
| R5800 |
T8884 |
T8883 |
equivalentTo |
MDM2,double minute 2 |
| R5801 |
T8885 |
T8883 |
equivalentTo |
p70 ribosomal protein S6 Kinase,double minute 2 |
| R5802 |
T8887 |
T8928 |
themeOf |
S6,phosphorylation |
| R5803 |
T8898 |
T8934 |
themeOf |
Raptor,inhibitor |
| R5804 |
T8903 |
T8939 |
themeOf |
S6,phosphorylation |
| R5805 |
T8904 |
T8940 |
themeOf |
S6,knockdown |
| R5806 |
T8908 |
T8943 |
themeOf |
TNFα,upregulation |
| R5807 |
T8909 |
T8945 |
themeOf |
TNFα,synthesis |
| R5808 |
T8912 |
T8947 |
themeOf |
TNFα,increase |
| R5809 |
T8915 |
T8949 |
causeOf |
bFGF,triggered |
| R5810 |
T8916 |
T8950 |
themeOf |
TNFα,induction |
| R5811 |
T8917 |
T8953 |
themeOf |
TNFα,upregulation |
| R5812 |
T8919 |
T8956 |
themeOf |
TNFα,upregulation |
| R5813 |
T8921 |
T8960 |
themeOf |
RIP1,inhibitors |
| R5814 |
T8923 |
T8962 |
themeOf |
bFGF,stimulated |
| R5815 |
T8926 |
T8925 |
themeOf |
phosphorylation,increase |
| R5816 |
T8928 |
T8927 |
themeOf |
phosphorylation,increase |
| R5817 |
T8930 |
T8929 |
themeOf |
phosphorylation,increase |
| R5818 |
T8939 |
T8938 |
themeOf |
phosphorylation,block |
| R5819 |
T8940 |
T8941 |
causeOf |
knockdown,attenuated |
| R5820 |
T8945 |
T8944 |
themeOf |
synthesis,increased |
| R5821 |
T8950 |
T8949 |
themeOf |
induction,triggered |
| R5822 |
T8953 |
T8952 |
themeOf |
upregulation,caused |
| R5823 |
T8953 |
T8954 |
themeOf |
upregulation,increased |
| R5824 |
T8956 |
T8955 |
themeOf |
upregulation,contribute |
| R7765 |
T11783 |
T11796 |
themeOf |
TNFα,increase |
| R7766 |
T11784 |
T11797 |
themeOf |
Akt1,Knockdown |
| R7767 |
T11785 |
T11797 |
themeOf |
Akt2,Knockdown |
| R7768 |
T11786 |
T11802 |
themeOf |
c-Jun,phosphorylation |
| R7769 |
T11789 |
T11807 |
themeOf |
c-Jun,phosphorylation |
| R7770 |
T11791 |
T11811 |
themeOf |
c-Jun,phosphorylation |
| R7771 |
T11796 |
T11795 |
themeOf |
increase,block |
| R7772 |
T11802 |
T11801 |
themeOf |
phosphorylation,increase |
| R7773 |
T11803 |
T11804 |
causeOf |
inhibition,inhibited |
| R7774 |
T11807 |
T11806 |
themeOf |
phosphorylation,induced |
| R7775 |
T11808 |
T11809 |
causeOf |
Knockdown,attenuated |
| R7776 |
T11810 |
T11809 |
themeOf |
increase,attenuated |
| R7777 |
T11811 |
T11810 |
themeOf |
phosphorylation,increase |
| R8390 |
T12690 |
T12697 |
causeOf |
PDK1,Increase |
| R8391 |
T12691 |
T12704 |
causeOf |
3-phosphoinositide dependent protein kinase-1,phosphorylated |
| R8392 |
T12692 |
T12691 |
equivalentTo |
PDK1,3-phosphoinositide dependent protein kinase-1 |
| R8393 |
T12693 |
T12707 |
causeOf |
PDK1,dependent |
| R8394 |
T12694 |
T12708 |
themeOf |
PDK1,Inhibition |
| R8395 |
T12695 |
T12712 |
themeOf |
PDK1,knockdown |
| R8396 |
T12696 |
T12715 |
causeOf |
PDK1,required |
| R8397 |
T12698 |
T12697 |
themeOf |
Phosphorylation,Increase |
| R8398 |
T12702 |
T12701 |
causeOf |
binding,mediated |
| R8399 |
T12703 |
T12702 |
themeOf |
pleckstrin homology (PH) domain,binding |
| R8400 |
T12705 |
T12706 |
themeOf |
phosphorylation,increased |
| R8401 |
T12705 |
T12707 |
themeOf |
phosphorylation,dependent |
| R8402 |
T12711 |
T12710 |
themeOf |
phosphorylation,inhibition |
| R8403 |
T12712 |
T12713 |
causeOf |
knockdown,inhibited |
| R8404 |
T12714 |
T12713 |
themeOf |
phosphorylation,inhibited |
| R8405 |
T12716 |
T12715 |
themeOf |
activation,required |
| R8889 |
T13454 |
T13498 |
themeOf |
Akt1,expressing |
| R8890 |
T13455 |
T13454 |
equivalentTo |
Myr-Akt,Akt1 |
| R8891 |
T13458 |
T13500 |
themeOf |
Akt1,localization |
| R8892 |
T13459 |
T13458 |
equivalentTo |
Myr-Akt,Akt1 |
| R8893 |
T13460 |
T13503 |
themeOf |
Myr-Akt,expressing |
| R8894 |
T13464 |
T13508 |
themeOf |
c-Jun,phosphorylation |
| R8895 |
T13465 |
T13509 |
themeOf |
TNFα,upregulation |
| R8896 |
T13466 |
T13513 |
causeOf |
RIP1,regulate |
| R8897 |
T13469 |
T13518 |
themeOf |
Myr-Akt,phosphorylation |
| R8898 |
T13471 |
T13523 |
themeOf |
Myr-Akt,expression |
| R8899 |
T13474 |
T13525 |
themeOf |
p70S6K,phosphorylated |
| R8900 |
T13475 |
T13525 |
themeOf |
S6,phosphorylated |
| R8901 |
T13476 |
T13525 |
themeOf |
FoxO4,phosphorylated |
| R8902 |
T13477 |
T13526 |
themeOf |
FoxO1,phosphorylation |
| R8903 |
T13478 |
T13526 |
themeOf |
MDM2,phosphorylation |
| R8904 |
T13479 |
T13528 |
themeOf |
Myr-Akt,phosphorylation |
| R8905 |
T13481 |
T13529 |
themeOf |
Myr-Akt,expressed |
| R8906 |
T13483 |
T13542 |
themeOf |
S473D mutant,phosphorylated |
| R8907 |
T13487 |
T13548 |
themeOf |
c-Jun,phosphorylation |
| R8908 |
T13488 |
T13548 |
themeOf |
TNFα,phosphorylation |
| R8909 |
T13490 |
T13549 |
themeOf |
T308D,phosphorylated |
| R8910 |
T13491 |
T13549 |
themeOf |
Myr-Akt,phosphorylated |
| R8911 |
T13494 |
T13549 |
themeOf |
MDM2,phosphorylated |
| R8912 |
T13495 |
T13549 |
causeOf |
p70S6K,phosphorylated |
| R8913 |
T13506 |
T13505 |
themeOf |
phosphorylation,increase |
| R8914 |
T13508 |
T13507 |
themeOf |
phosphorylation,activation |
| R8915 |
T13511 |
T13510 |
themeOf |
uncouple,sufficient |
| R8916 |
T13512 |
T13511 |
themeOf |
activation,uncouple |
| R8917 |
T13514 |
T13513 |
themeOf |
activation,regulate |
| R8918 |
T13516 |
T13515 |
themeOf |
changes,required |
| R8919 |
T13523 |
T13521 |
causeOf |
expression,increased |
| R8920 |
T13523 |
T13522 |
themeOf |
expression,upon |
| R8921 |
T13526 |
T13527 |
themeOf |
phosphorylation,increased |
| R8922 |
T13533 |
T13532 |
themeOf |
PH domain,lacking |
| R8923 |
T13535 |
T13534 |
themeOf |
phosphorylation,increased |
| R8924 |
T13535 |
T13536 |
themeOf |
phosphorylation,following |
| R8925 |
T13538 |
T13537 |
themeOf |
phosphorylation,role |
| R8926 |
T13540 |
T13541 |
causeOf |
mutations,reduction |
