Id |
Subject |
Object |
Predicate |
Lexical cue |
T606 |
919-927 |
Negative_regulation |
denotes |
knockout |
T2032 |
4118-4127 |
Gene_expression |
denotes |
expressed |
T3097 |
6526-6533 |
Protein |
denotes |
β-actin |
T3370 |
7452-7456 |
Protein |
denotes |
MMP9 |
T4040 |
8352-8370 |
Protein |
denotes |
interleukin-1 beta |
T4041 |
8372-8377 |
Protein |
denotes |
IL-1β |
T4042 |
8384-8397 |
Protein |
denotes |
interleukin-6 |
T4043 |
8399-8403 |
Protein |
denotes |
IL-6 |
T4372 |
9820-9824 |
Protein |
denotes |
MMP9 |
T4373 |
10076-10080 |
Protein |
denotes |
MMP9 |
T4843 |
10386-10395 |
Negative_regulation |
denotes |
Depletion |
T5102 |
10946-10956 |
Negative_regulation |
denotes |
Disruption |
T5103 |
10965-10973 |
Positive_regulation |
denotes |
Enhanced |
T5104 |
10974-10986 |
Positive_regulation |
denotes |
Upregulation |
T5369 |
11576-11581 |
Protein |
denotes |
IL-1β |
T5370 |
11587-11591 |
Protein |
denotes |
IL-6 |
T5381 |
11596-11605 |
Regulation |
denotes |
regulated |
T5382 |
11884-11893 |
Negative_regulation |
denotes |
deficient |
T5371 |
12058-12063 |
Protein |
denotes |
IL-1β |
T5372 |
12069-12073 |
Protein |
denotes |
IL-6 |
T5383 |
12169-12180 |
Transcription |
denotes |
mRNA levels |
T5373 |
12191-12196 |
Protein |
denotes |
IL-1β |
T5374 |
12202-12206 |
Protein |
denotes |
IL-6 |
T5384 |
12212-12221 |
Positive_regulation |
denotes |
increased |
T5375 |
12510-12515 |
Protein |
denotes |
IL-1β |
T5376 |
12558-12562 |
Protein |
denotes |
IL-6 |
T5385 |
12661-12672 |
Positive_regulation |
denotes |
upregulated |
T5377 |
12932-12936 |
Protein |
denotes |
IL-6 |
T5378 |
12941-12946 |
Protein |
denotes |
IL-1β |
T5379 |
12952-12956 |
Protein |
denotes |
IL-6 |
T5380 |
13063-13068 |
Protein |
denotes |
IL-1β |
T6446 |
13206-13210 |
Protein |
denotes |
MMP9 |
T6447 |
13282-13286 |
Protein |
denotes |
MMP9 |
T6448 |
13439-13443 |
Protein |
denotes |
MMP9 |
T6453 |
13537-13547 |
Gene_expression |
denotes |
Expression |
T6449 |
13551-13555 |
Protein |
denotes |
MMP9 |
T6450 |
13674-13678 |
Protein |
denotes |
MMP9 |
T6451 |
13843-13847 |
Protein |
denotes |
MMP9 |
T6452 |
14005-14009 |
Protein |
denotes |
MMP9 |
T7080 |
14191-14198 |
Positive_regulation |
denotes |
induced |
T7081 |
14203-14215 |
Positive_regulation |
denotes |
upregulation |
T7082 |
14250-14264 |
Positive_regulation |
denotes |
overexpression |
T7052 |
14275-14280 |
Protein |
denotes |
IL-1β |
T7053 |
14282-14286 |
Protein |
denotes |
IL-6 |
T7054 |
14292-14296 |
Protein |
denotes |
MMP9 |
T7083 |
14670-14675 |
Binding |
denotes |
binds |
T7055 |
14736-14740 |
Protein |
denotes |
MMP9 |
T7056 |
14802-14807 |
Protein |
denotes |
IL-1β |
T7057 |
14813-14817 |
Protein |
denotes |
IL-6 |
T7058 |
14972-14976 |
Protein |
denotes |
MMP9 |
T7059 |
15172-15177 |
Protein |
denotes |
IL-1β |
T7060 |
15205-15209 |
Protein |
denotes |
MMP9 |
T7061 |
15238-15242 |
Protein |
denotes |
IL-6 |
T7062 |
15269-15273 |
Protein |
denotes |
MMP9 |
T7063 |
15325-15330 |
Protein |
denotes |
IL-1β |
T7064 |
15954-15970 |
Protein |
denotes |
heme oxygenase-1 |
T7065 |
15972-15976 |
Protein |
denotes |
HO-1 |
T7084 |
16369-16378 |
Negative_regulation |
denotes |
deficient |
T7085 |
16416-16425 |
Negative_regulation |
denotes |
Depletion |
T7086 |
16546-16560 |
Positive_regulation |
denotes |
overexpression |
T7066 |
16571-16576 |
Protein |
denotes |
IL-1β |
T7067 |
16578-16582 |
Protein |
denotes |
IL-6 |
T7068 |
16588-16592 |
Protein |
denotes |
MMP9 |
T7087 |
16651-16659 |
Negative_regulation |
denotes |
knockout |
T7088 |
17038-17045 |
Negative_regulation |
denotes |
inhibit |
T7089 |
17054-17069 |
Phosphorylation |
denotes |
phosphorylation |
T7069 |
17074-17077 |
Protein |
denotes |
p65 |
T7090 |
17092-17099 |
Entity |
denotes |
nuclear |
T7091 |
17100-17113 |
Localization |
denotes |
translocation |
T7092 |
17228-17238 |
Negative_regulation |
denotes |
attenuated |
T7093 |
17352-17361 |
Negative_regulation |
denotes |
depletion |
T7094 |
17710-17719 |
Negative_regulation |
denotes |
deficient |
T7095 |
17802-17809 |
Negative_regulation |
denotes |
inhibit |
T7070 |
17847-17850 |
Protein |
denotes |
p65 |
T7096 |
17859-17868 |
Negative_regulation |
denotes |
repressed |
T7097 |
17930-17941 |
Binding |
denotes |
interaction |
T7098 |
17959-17965 |
Entity |
denotes |
domain |
T7099 |
18112-18121 |
Regulation |
denotes |
regulated |
T7100 |
18533-18543 |
Gene_expression |
denotes |
expression |
T7071 |
18554-18559 |
Protein |
denotes |
IL-1β |
T7072 |
18565-18569 |
Protein |
denotes |
IL-6 |
T7073 |
18713-18717 |
Protein |
denotes |
MMP9 |
T7101 |
19043-19054 |
Positive_regulation |
denotes |
upregulated |
T7102 |
19055-19065 |
Gene_expression |
denotes |
expression |
T7074 |
19076-19081 |
Protein |
denotes |
IL-1β |
T7075 |
19083-19087 |
Protein |
denotes |
IL-6 |
T7076 |
19093-19097 |
Protein |
denotes |
MMP9 |
T7103 |
19106-19114 |
Negative_regulation |
denotes |
knockout |
T7104 |
19182-19191 |
Negative_regulation |
denotes |
depletion |
T7105 |
19200-19207 |
Positive_regulation |
denotes |
induced |
T7106 |
19212-19222 |
Positive_regulation |
denotes |
activation |
T7107 |
19240-19250 |
Gene_expression |
denotes |
expression |
T7077 |
19261-19266 |
Protein |
denotes |
IL-1β |
T7078 |
19268-19272 |
Protein |
denotes |
IL-6 |
T7079 |
19278-19282 |
Protein |
denotes |
MMP9 |
R3486 |
T4041 |
T4040 |
equivalentTo |
IL-1β,interleukin-1 beta |
R3487 |
T4043 |
T4042 |
equivalentTo |
IL-6,interleukin-6 |
R4343 |
T5104 |
T5103 |
themeOf |
Upregulation,Enhanced |
R4554 |
T5369 |
T5381 |
themeOf |
IL-1β,regulated |
R4555 |
T5370 |
T5381 |
themeOf |
IL-6,regulated |
R4556 |
T5373 |
T5383 |
themeOf |
IL-1β,mRNA levels |
R4557 |
T5373 |
T5384 |
themeOf |
IL-1β,increased |
R4558 |
T5374 |
T5384 |
themeOf |
IL-6,increased |
R4559 |
T5374 |
T5383 |
themeOf |
IL-6,mRNA levels |
R4560 |
T5383 |
T5384 |
themeOf |
mRNA levels,increased |
R5371 |
T6449 |
T6453 |
themeOf |
MMP9,Expression |
R5809 |
T7052 |
T7081 |
themeOf |
IL-1β,upregulation |
R5810 |
T7052 |
T7082 |
themeOf |
IL-1β,overexpression |
R5811 |
T7053 |
T7082 |
themeOf |
IL-6,overexpression |
R5812 |
T7054 |
T7082 |
themeOf |
MMP9,overexpression |
R5813 |
T7065 |
T7064 |
equivalentTo |
HO-1,heme oxygenase-1 |
R5814 |
T7066 |
T7086 |
themeOf |
IL-1β,overexpression |
R5815 |
T7067 |
T7086 |
themeOf |
IL-6,overexpression |
R5816 |
T7068 |
T7086 |
themeOf |
MMP9,overexpression |
R5817 |
T7069 |
T7091 |
themeOf |
p65,translocation |
R5818 |
T7070 |
T7097 |
themeOf |
p65,interaction |
R5819 |
T7071 |
T7100 |
themeOf |
IL-1β,expression |
R5820 |
T7072 |
T7100 |
themeOf |
IL-6,expression |
R5821 |
T7074 |
T7102 |
themeOf |
IL-1β,expression |
R5822 |
T7075 |
T7102 |
themeOf |
IL-6,expression |
R5823 |
T7076 |
T7102 |
themeOf |
MMP9,expression |
R5824 |
T7077 |
T7107 |
themeOf |
IL-1β,expression |
R5825 |
T7078 |
T7107 |
themeOf |
IL-6,expression |
R5826 |
T7079 |
T7107 |
themeOf |
MMP9,expression |
R5827 |
T7081 |
T7080 |
themeOf |
upregulation,induced |
R5828 |
T7089 |
T7088 |
themeOf |
phosphorylation,inhibit |
R5829 |
T7090 |
T7091 |
locationOf |
nuclear,translocation |
R5830 |
T7091 |
T7088 |
themeOf |
translocation,inhibit |
R5831 |
T7097 |
T7096 |
causeOf |
interaction,repressed |
R5832 |
T7102 |
T7101 |
themeOf |
expression,upregulated |
R5833 |
T7106 |
T7105 |
themeOf |
activation,induced |