| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T259 |
1707-1711 |
Protein |
denotes |
p100 |
| T260 |
1715-1721 |
Protein |
denotes |
NF-κB2 |
| T261 |
1723-1727 |
Protein |
denotes |
p105 |
| T262 |
1731-1737 |
Protein |
denotes |
NF-κB1 |
| T263 |
1739-1742 |
Protein |
denotes |
p65 |
| T264 |
1746-1750 |
Protein |
denotes |
RelA |
| T265 |
1752-1756 |
Protein |
denotes |
RelB |
| T266 |
1758-1763 |
Protein |
denotes |
c-Rel |
| T278 |
1823-1831 |
Regulation |
denotes |
regulate |
| T279 |
1836-1846 |
Gene_expression |
denotes |
expression |
| T267 |
1884-1887 |
Protein |
denotes |
TNF |
| T268 |
1895-1899 |
Protein |
denotes |
IL-6 |
| T269 |
1901-1918 |
Protein |
denotes |
cyclo-oxygenase-2 |
| T270 |
1932-1963 |
Protein |
denotes |
inducible nitric oxide synthase |
| T271 |
2035-2038 |
Protein |
denotes |
TNF |
| T272 |
2654-2688 |
Protein |
denotes |
receptor activator of NF-κB ligand |
| T273 |
2690-2695 |
Protein |
denotes |
RANKL |
| T280 |
2869-2880 |
Binding |
denotes |
association |
| T274 |
2940-2944 |
Protein |
denotes |
CD40 |
| T275 |
2946-2951 |
Protein |
denotes |
TRAF1 |
| T276 |
2953-2960 |
Protein |
denotes |
TNFAIP3 |
| T277 |
2966-2971 |
Protein |
denotes |
c-REL |
| T1640 |
3316-3319 |
Protein |
denotes |
TNF |
| T1641 |
3375-3378 |
Protein |
denotes |
TNF |
| T1642 |
3450-3453 |
Protein |
denotes |
TNF |
| T1643 |
3664-3691 |
Protein |
denotes |
receptor activator of NF-κB |
| T1644 |
3693-3697 |
Protein |
denotes |
RANK |
| T1645 |
3789-3793 |
Protein |
denotes |
RANK |
| T1646 |
3903-3907 |
Protein |
denotes |
CD40 |
| T1647 |
3919-3945 |
Protein |
denotes |
TNF receptor family member |
| T1670 |
3967-3976 |
Gene_expression |
denotes |
expressed |
| T1671 |
4146-4157 |
Positive_regulation |
denotes |
upregulated |
| T1648 |
4197-4200 |
Protein |
denotes |
TNF |
| T1672 |
4207-4214 |
Binding |
denotes |
Binding |
| T1649 |
4222-4233 |
Protein |
denotes |
CD40 ligand |
| T1650 |
4235-4240 |
Protein |
denotes |
CD154 |
| T1673 |
4264-4273 |
Gene_expression |
denotes |
expressed |
| T1651 |
4302-4305 |
Protein |
denotes |
CD4 |
| T1652 |
4576-4580 |
Protein |
denotes |
CD40 |
| T1674 |
4756-4764 |
Positive_regulation |
denotes |
Enhanced |
| T1675 |
4765-4775 |
Gene_expression |
denotes |
expression |
| T1653 |
4810-4834 |
Protein |
denotes |
B-cell activating factor |
| T1654 |
4836-4840 |
Protein |
denotes |
BAFF |
| T1676 |
4882-4891 |
Gene_expression |
denotes |
producing |
| T1655 |
4957-4961 |
Protein |
denotes |
BAFF |
| T1656 |
5011-5033 |
Protein |
denotes |
lymphotoxin β receptor |
| T1657 |
5880-5925 |
Protein |
denotes |
High mobility group box chromosomal protein 1 |
| T1658 |
5927-5932 |
Protein |
denotes |
HMGB1 |
| T1659 |
5954-5973 |
Protein |
denotes |
chromatin component |
| T1677 |
5995-6003 |
Localization |
denotes |
secreted |
| T1678 |
6032-6040 |
Localization |
denotes |
released |
| T1660 |
6099-6111 |
Protein |
denotes |
TLR4 ligands |
| T1661 |
6138-6143 |
Protein |
denotes |
HMGB1 |
| T1679 |
6147-6156 |
Positive_regulation |
denotes |
increased |
| T1662 |
6183-6188 |
Protein |
denotes |
HMGB1 |
| T1663 |
6248-6253 |
Protein |
denotes |
HMGB1 |
| T1664 |
6311-6336 |
Protein |
denotes |
Myeloid-related protein 8 |
| T1665 |
6341-6367 |
Protein |
denotes |
myeloid-related protein 14 |
| T1666 |
6565-6569 |
Protein |
denotes |
TLR4 |
| T1667 |
6736-6747 |
Protein |
denotes |
fibronectin |
| T1668 |
6749-6757 |
Protein |
denotes |
biglycan |
| T1669 |
6759-6769 |
Protein |
denotes |
tenascin C |
| T3951 |
7171-7178 |
Negative_regulation |
denotes |
prevent |
| T3952 |
7185-7192 |
Entity |
denotes |
nuclear |
| T3953 |
7193-7206 |
Localization |
denotes |
translocation |
| T3840 |
7259-7263 |
Protein |
denotes |
IκBα |
| T3841 |
7265-7269 |
Protein |
denotes |
IκBβ |
| T3842 |
7271-7275 |
Protein |
denotes |
IκBε |
| T3843 |
7277-7281 |
Protein |
denotes |
p105 |
| T3844 |
7297-7303 |
Protein |
denotes |
NF-κB1 |
| T3845 |
7306-7310 |
Protein |
denotes |
p100 |
| T3846 |
7326-7332 |
Protein |
denotes |
NF-κB2 |
| T3954 |
7344-7354 |
Negative_regulation |
denotes |
inhibitors |
| T3847 |
7365-7369 |
Protein |
denotes |
IκBξ |
| T3848 |
7374-7379 |
Protein |
denotes |
Bcl-3 |
| T3849 |
7437-7441 |
Protein |
denotes |
p100 |
| T3850 |
7446-7450 |
Protein |
denotes |
p105 |
| T3851 |
7473-7476 |
Protein |
denotes |
p52 |
| T3852 |
7481-7484 |
Protein |
denotes |
p50 |
| T3853 |
7808-7811 |
Protein |
denotes |
TNF |
| T3854 |
7830-7835 |
Protein |
denotes |
RANKL |
| T3955 |
8092-8107 |
Phosphorylation |
denotes |
phosphorylation |
| T3956 |
8180-8191 |
Protein_catabolism |
denotes |
degradation |
| T3855 |
8275-8279 |
Protein |
denotes |
IKK1 |
| T3856 |
8284-8288 |
Protein |
denotes |
IKK2 |
| T3857 |
8304-8308 |
Protein |
denotes |
IKKα |
| T3858 |
8313-8317 |
Protein |
denotes |
IKKβ |
| T3859 |
8346-8371 |
Protein |
denotes |
NF-κB essential modulator |
| T3860 |
8373-8377 |
Protein |
denotes |
NEMO |
| T3861 |
8394-8398 |
Protein |
denotes |
IKKγ |
| T3862 |
8451-8455 |
Protein |
denotes |
IKK2 |
| T3863 |
8460-8464 |
Protein |
denotes |
NEMO |
| T3864 |
8474-8478 |
Protein |
denotes |
IKK1 |
| T19316 |
8599-8609 |
Binding |
denotes |
engagement |
| T19260 |
8649-8654 |
Protein |
denotes |
TNFR1 |
| T19261 |
8656-8660 |
Protein |
denotes |
CD40 |
| T19262 |
8662-8666 |
Protein |
denotes |
RANK |
| T19263 |
8672-8676 |
Protein |
denotes |
TLR4 |
| T19317 |
8677-8684 |
Positive_regulation |
denotes |
trigger |
| T19318 |
8689-8700 |
Binding |
denotes |
recruitment |
| T19264 |
8731-8777 |
Protein |
denotes |
TNF receptor 1-associated death domain protein |
| T19265 |
8779-8784 |
Protein |
denotes |
TRADD |
| T19266 |
8787-8792 |
Protein |
denotes |
MyD88 |
| T19267 |
8794-8797 |
Protein |
denotes |
MAL |
| T19268 |
8799-8842 |
Protein |
denotes |
TIR domain-containing adaptor-inducing IFNβ |
| T19319 |
8829-8837 |
Positive_regulation |
denotes |
inducing |
| T19269 |
8844-8848 |
Protein |
denotes |
TRIF |
| T19270 |
8861-8865 |
Protein |
denotes |
RIP1 |
| T19271 |
8867-8872 |
Protein |
denotes |
IRAK1 |
| T19272 |
8874-8879 |
Protein |
denotes |
IRAK4 |
| T19273 |
8905-8910 |
Protein |
denotes |
TRAF2 |
| T19274 |
8912-8917 |
Protein |
denotes |
TRAF6 |
| T19275 |
8919-8924 |
Protein |
denotes |
cIAP1 |
| T19276 |
8926-8931 |
Protein |
denotes |
cIAP2 |
| T19277 |
8990-8994 |
Protein |
denotes |
RIP1 |
| T19278 |
8999-9004 |
Protein |
denotes |
IRAK1 |
| T19279 |
9023-9027 |
Protein |
denotes |
NEMO |
| T19280 |
9106-9110 |
Protein |
denotes |
IKK2 |
| T19281 |
9115-9119 |
Protein |
denotes |
TAK1 |
| T19282 |
9121-9125 |
Protein |
denotes |
TAK1 |
| T19283 |
9160-9164 |
Protein |
denotes |
IKK2 |
| T19320 |
9180-9194 |
Phosphorylation |
denotes |
phosphorylates |
| T19284 |
9195-9199 |
Protein |
denotes |
IκBα |
| T19321 |
9258-9269 |
Protein_catabolism |
denotes |
degradation |
| T19285 |
9321-9324 |
Protein |
denotes |
p65 |
| T19286 |
9329-9332 |
Protein |
denotes |
p50 |
| T19322 |
9337-9348 |
Localization |
denotes |
translocate |
| T19323 |
9356-9363 |
Entity |
denotes |
nucleus |
| T19287 |
9400-9405 |
Protein |
denotes |
TRAF1 |
| T19288 |
9534-9537 |
Protein |
denotes |
A20 |
| T19289 |
9542-9546 |
Protein |
denotes |
CYLD |
| T19290 |
9658-9662 |
Protein |
denotes |
RIP1 |
| T19291 |
9667-9672 |
Protein |
denotes |
TRAF6 |
| T19324 |
9692-9701 |
Binding |
denotes |
recruited |
| T19325 |
9727-9734 |
Binding |
denotes |
binding |
| T19292 |
9760-9766 |
Protein |
denotes |
ABIN-1 |
| T19293 |
9771-9774 |
Protein |
denotes |
p62 |
| T19326 |
9836-9846 |
Negative_regulation |
denotes |
inhibiting |
| T19327 |
9847-9857 |
Gene_expression |
denotes |
expression |
| T19294 |
9861-9866 |
Protein |
denotes |
IRAK1 |
| T19295 |
9871-9876 |
Protein |
denotes |
TRAF6 |
| T19328 |
9914-9923 |
Negative_regulation |
denotes |
inhibited |
| T19296 |
9953-9959 |
Protein |
denotes |
SIGIRR |
| T19329 |
9988-9995 |
Negative_regulation |
denotes |
compete |
| T19297 |
10001-10005 |
Protein |
denotes |
TLR4 |
| T19330 |
10010-10017 |
Binding |
denotes |
binding |
| T19298 |
10021-10026 |
Protein |
denotes |
IRAK1 |
| T19299 |
10031-10036 |
Protein |
denotes |
TRAF6 |
| T19300 |
10194-10198 |
Protein |
denotes |
ABIN |
| T19301 |
10200-10230 |
Protein |
denotes |
A20-binding inhibitor of NF-κB |
| T19302 |
10271-10275 |
Protein |
denotes |
CYLD |
| T19303 |
10277-10292 |
Protein |
denotes |
cylindromatosis |
| T19331 |
10316-10325 |
Negative_regulation |
denotes |
inhibitor |
| T19304 |
10367-10372 |
Protein |
denotes |
MyD88 |
| T19305 |
10374-10422 |
Protein |
denotes |
myeloid differentiation primary response gene 88 |
| T19306 |
10424-10428 |
Protein |
denotes |
NEMO |
| T19307 |
10430-10455 |
Protein |
denotes |
NF-κB essential modulator |
| T19308 |
10477-10481 |
Protein |
denotes |
RANK |
| T19309 |
10483-10510 |
Protein |
denotes |
receptor activator of NF-κB |
| T19310 |
10512-10516 |
Protein |
denotes |
RIP1 |
| T19311 |
10518-10548 |
Protein |
denotes |
receptor interacting protein 1 |
| T19312 |
10550-10556 |
Protein |
denotes |
SIGIRR |
| T19313 |
10558-10600 |
Protein |
denotes |
single-immunoglobulinIL-1 receptor-related |
| T19314 |
10696-10699 |
Protein |
denotes |
TNF |
| T19315 |
10701-10723 |
Protein |
denotes |
tumour necrosis factor |
| T3865 |
10782-10785 |
Protein |
denotes |
TNF |
| T3866 |
10795-10798 |
Protein |
denotes |
TNF |
| T3957 |
10826-10837 |
Binding |
denotes |
recruitment |
| T3867 |
10841-10879 |
Protein |
denotes |
TNF receptor-1-associated death domain |
| T3868 |
10881-10886 |
Protein |
denotes |
TRADD |
| T3869 |
10903-10933 |
Protein |
denotes |
receptor interacting protein 1 |
| T3870 |
10935-10939 |
Protein |
denotes |
RIP1 |
| T3871 |
11006-11045 |
Protein |
denotes |
TNF receptor-associated factor (TRAF) 2 |
| T3872 |
11050-11055 |
Protein |
denotes |
TRAF5 |
| T3958 |
11071-11075 |
Binding |
denotes |
bind |
| T3873 |
11101-11141 |
Protein |
denotes |
cellular inhibitor of apoptosis (cIAP) 1 |
| T3874 |
11146-11151 |
Protein |
denotes |
cIAP2 |
| T3875 |
11167-11170 |
Protein |
denotes |
TNF |
| T3959 |
11197-11202 |
Binding |
denotes |
bound |
| T3876 |
11203-11207 |
Protein |
denotes |
RIP1 |
| T3877 |
11264-11269 |
Protein |
denotes |
TRAF2 |
| T3878 |
11270-11271 |
Protein |
denotes |
5 |
| T3879 |
11276-11281 |
Protein |
denotes |
cIAP1 |
| T3880 |
11282-11283 |
Protein |
denotes |
2 |
| T3881 |
11308-11312 |
Protein |
denotes |
RIP1 |
| T3882 |
11405-11409 |
Protein |
denotes |
RIP1 |
| T3960 |
11447-11454 |
Binding |
denotes |
recruit |
| T3883 |
11467-11471 |
Protein |
denotes |
TAK1 |
| T3961 |
11488-11498 |
Entity |
denotes |
ubiquitin- |
| T3962 |
11498-11505 |
Binding |
denotes |
binding |
| T3884 |
11515-11519 |
Protein |
denotes |
NEMO |
| T3885 |
11524-11528 |
Protein |
denotes |
TAB1 |
| T3886 |
11529-11530 |
Protein |
denotes |
2 |
| T3887 |
11621-11625 |
Protein |
denotes |
NEMO |
| T3888 |
11680-11683 |
Protein |
denotes |
TNF |
| T3889 |
11906-11910 |
Protein |
denotes |
TAK1 |
| T3890 |
11994-11998 |
Protein |
denotes |
TLR4 |
| T3963 |
12033-12040 |
Positive_regulation |
denotes |
induces |
| T3964 |
12045-12056 |
Binding |
denotes |
recruitment |
| T3891 |
12060-12094 |
Protein |
denotes |
Toll/IL-1 receptor adaptor protein |
| T3892 |
12116-12118 |
Protein |
denotes |
Ma |
| T3893 |
12125-12154 |
Protein |
denotes |
TRIF-related adaptor molecule |
| T3894 |
12156-12160 |
Protein |
denotes |
TRAM |
| T3895 |
12220-12268 |
Protein |
denotes |
myeloid differentiation primary response gene 88 |
| T3896 |
12270-12275 |
Protein |
denotes |
MyD88 |
| T3897 |
12281-12324 |
Protein |
denotes |
TIR domain-containing adaptor-inducing IFNβ |
| T3965 |
12311-12319 |
Positive_regulation |
denotes |
inducing |
| T3898 |
12326-12330 |
Protein |
denotes |
TRIF |
| T3899 |
12347-12352 |
Protein |
denotes |
MyD88 |
| T3900 |
12427-12432 |
Protein |
denotes |
TRAF6 |
| T3966 |
12465-12483 |
Negative_regulation |
denotes |
selfubiquitination |
| T3901 |
12487-12492 |
Protein |
denotes |
TRAF6 |
| T3902 |
12499-12503 |
Protein |
denotes |
TRIF |
| T3967 |
12509-12517 |
Binding |
denotes |
recruits |
| T3903 |
12518-12523 |
Protein |
denotes |
TRAF6 |
| T3904 |
12533-12537 |
Protein |
denotes |
RIP1 |
| T3968 |
12556-12567 |
Binding |
denotes |
interaction |
| T3969 |
12588-12596 |
Positive_regulation |
denotes |
activate |
| T3905 |
12597-12601 |
Protein |
denotes |
TAK1 |
| T3906 |
12662-12665 |
Protein |
denotes |
TNF |
| T3907 |
12741-12763 |
Protein |
denotes |
lymphotoxin β receptor |
| T3908 |
12765-12778 |
Protein |
denotes |
BAFF receptor |
| T3909 |
12780-12784 |
Protein |
denotes |
CD40 |
| T3910 |
12790-12794 |
Protein |
denotes |
RANK |
| T3911 |
12824-12828 |
Protein |
denotes |
p100 |
| T3912 |
12863-12866 |
Protein |
denotes |
p52 |
| T3913 |
12892-12896 |
Protein |
denotes |
RelB |
| T3914 |
13107-13111 |
Protein |
denotes |
IKK1 |
| T3970 |
13137-13152 |
Phosphorylation |
denotes |
phosphorylation |
| T3915 |
13156-13177 |
Protein |
denotes |
NF-κB inducing kinase |
| T3916 |
13179-13182 |
Protein |
denotes |
NIK |
| T3917 |
13185-13188 |
Protein |
denotes |
NIK |
| T3971 |
13206-13215 |
Regulation |
denotes |
regulated |
| T3972 |
13227-13241 |
Protein_modification |
denotes |
-translational |
| T3918 |
13330-13333 |
Protein |
denotes |
NIK |
| T3919 |
13371-13376 |
Protein |
denotes |
TRAF2 |
| T3920 |
13378-13383 |
Protein |
denotes |
TRAF3 |
| T3921 |
13389-13394 |
Protein |
denotes |
cIAP1 |
| T3922 |
13395-13396 |
Protein |
denotes |
2 |
| T3923 |
13426-13429 |
Protein |
denotes |
NIK |
| T3973 |
13457-13468 |
Protein_catabolism |
denotes |
degradation |
| T3924 |
13540-13545 |
Protein |
denotes |
TRAF3 |
| T3925 |
13618-13623 |
Protein |
denotes |
TRAF2 |
| T3926 |
13628-13633 |
Protein |
denotes |
cIAP1 |
| T3927 |
13634-13635 |
Protein |
denotes |
2 |
| T3928 |
13672-13677 |
Protein |
denotes |
TRAF3 |
| T3974 |
13678-13689 |
Protein_catabolism |
denotes |
degradation |
| T3929 |
13725-13728 |
Protein |
denotes |
NIK |
| T3975 |
13751-13762 |
Protein_catabolism |
denotes |
degradation |
| T3930 |
13777-13780 |
Protein |
denotes |
NIK |
| T3931 |
13798-13802 |
Protein |
denotes |
IKK1 |
| T3976 |
13803-13818 |
Phosphorylation |
denotes |
phosphorylation |
| T21283 |
13880-13884 |
Protein |
denotes |
CD40 |
| T21284 |
13889-13893 |
Protein |
denotes |
RANK |
| T21285 |
13959-13980 |
Protein |
denotes |
NF-κB inducing kinase |
| T21286 |
13982-13985 |
Protein |
denotes |
NIK |
| T21317 |
13987-13997 |
Gene_expression |
denotes |
expression |
| T21287 |
14028-14031 |
Protein |
denotes |
NIK |
| T21288 |
14085-14090 |
Protein |
denotes |
TRAF2 |
| T21289 |
14092-14097 |
Protein |
denotes |
TRAF3 |
| T21290 |
14102-14107 |
Protein |
denotes |
cIAP1 |
| T21291 |
14108-14109 |
Protein |
denotes |
2 |
| T21318 |
14179-14190 |
Protein_catabolism |
denotes |
degradation |
| T21292 |
14194-14197 |
Protein |
denotes |
NIK |
| T21293 |
14207-14210 |
Protein |
denotes |
NIK |
| T21294 |
14244-14249 |
Protein |
denotes |
TRAF3 |
| T21319 |
14253-14262 |
Binding |
denotes |
recruited |
| T21295 |
14286-14291 |
Protein |
denotes |
TRAF2 |
| T21296 |
14348-14353 |
Protein |
denotes |
cIAP1 |
| T21297 |
14354-14355 |
Protein |
denotes |
2 |
| T21298 |
14401-14406 |
Protein |
denotes |
cIAP1 |
| T21299 |
14407-14408 |
Protein |
denotes |
2 |
| T21300 |
14454-14459 |
Protein |
denotes |
TRAF3 |
| T21301 |
14473-14476 |
Protein |
denotes |
NIK |
| T21302 |
14491-14496 |
Protein |
denotes |
TRAF3 |
| T21303 |
14513-14516 |
Protein |
denotes |
NIK |
| T21320 |
14545-14554 |
Positive_regulation |
denotes |
increased |
| T21304 |
14555-14558 |
Protein |
denotes |
NIK |
| T21305 |
14579-14582 |
Protein |
denotes |
NIK |
| T21321 |
14588-14602 |
Phosphorylation |
denotes |
phosphorylates |
| T21306 |
14617-14621 |
Protein |
denotes |
IKK1 |
| T21322 |
14629-14637 |
Positive_regulation |
denotes |
mediates |
| T21307 |
14644-14648 |
Protein |
denotes |
p100 |
| T21323 |
14649-14664 |
Phosphorylation |
denotes |
phosphorylation |
| T21324 |
14740-14751 |
Protein_catabolism |
denotes |
degradation |
| T21308 |
14755-14759 |
Protein |
denotes |
p100 |
| T21309 |
14763-14766 |
Protein |
denotes |
p52 |
| T21310 |
14799-14803 |
Protein |
denotes |
RelB |
| T21311 |
14839-14844 |
Protein |
denotes |
TRAF3 |
| T21312 |
14846-14851 |
Protein |
denotes |
TRAF1 |
| T21313 |
15065-15069 |
Protein |
denotes |
RANK |
| T21314 |
15071-15098 |
Protein |
denotes |
receptor activator of NF-κB |
| T21315 |
15138-15141 |
Protein |
denotes |
TNF |
| T21316 |
15143-15165 |
Protein |
denotes |
tumour necrosis factor |
| T3932 |
15195-15199 |
Protein |
denotes |
CD40 |
| T3933 |
15201-15223 |
Protein |
denotes |
lymphotoxin β receptor |
| T3934 |
15228-15232 |
Protein |
denotes |
RANK |
| T3977 |
15323-15330 |
Binding |
denotes |
binding |
| T3935 |
15348-15352 |
Protein |
denotes |
CD40 |
| T3936 |
15357-15361 |
Protein |
denotes |
RANK |
| T3978 |
15362-15370 |
Binding |
denotes |
interact |
| T3937 |
15408-15413 |
Protein |
denotes |
TRAF1 |
| T3938 |
15415-15420 |
Protein |
denotes |
TRAF2 |
| T3939 |
15422-15427 |
Protein |
denotes |
TRAF3 |
| T3940 |
15429-15434 |
Protein |
denotes |
TRAF5 |
| T3941 |
15440-15445 |
Protein |
denotes |
TRAF6 |
| T3979 |
15456-15461 |
Positive_regulation |
denotes |
leads |
| T3980 |
15469-15480 |
Protein_catabolism |
denotes |
proteolysis |
| T3942 |
15489-15494 |
Protein |
denotes |
TRAF2 |
| T3943 |
15499-15504 |
Protein |
denotes |
TRAF3 |
| T3944 |
15676-15680 |
Protein |
denotes |
CD40 |
| T3945 |
15725-15730 |
Protein |
denotes |
TRAF6 |
| T3981 |
15734-15742 |
Positive_regulation |
denotes |
required |
| T3946 |
15747-15751 |
Protein |
denotes |
CD40 |
| T3982 |
15752-15760 |
Positive_regulation |
denotes |
mediated |
| T3947 |
15780-15784 |
Protein |
denotes |
IL-6 |
| T3983 |
15785-15795 |
Gene_expression |
denotes |
production |
| T3948 |
15803-15808 |
Protein |
denotes |
TRAF2 |
| T3949 |
15850-15855 |
Protein |
denotes |
TRAF3 |
| T3950 |
15890-15894 |
Protein |
denotes |
CD40 |
| T8331 |
16895-16901 |
Protein |
denotes |
MyD88s |
| T8332 |
16903-16909 |
Protein |
denotes |
IRAK-M |
| T8333 |
16915-16921 |
Protein |
denotes |
TOLLIP |
| T8334 |
17069-17073 |
Protein |
denotes |
IKK1 |
| T8335 |
17297-17301 |
Protein |
denotes |
IKK1 |
| T8344 |
17302-17311 |
Negative_regulation |
denotes |
deficient |
| T8345 |
17333-17343 |
Gene_expression |
denotes |
expressing |
| T8336 |
17353-17357 |
Protein |
denotes |
IKK1 |
| T8346 |
17428-17436 |
Positive_regulation |
denotes |
enhanced |
| T8337 |
17437-17441 |
Protein |
denotes |
IKK2 |
| T8338 |
17457-17461 |
Protein |
denotes |
IκBα |
| T8347 |
17462-17473 |
Protein_catabolism |
denotes |
degradation |
| T8339 |
17480-17484 |
Protein |
denotes |
IKK1 |
| T8340 |
17596-17601 |
Protein |
denotes |
STAT1 |
| T8341 |
17660-17664 |
Protein |
denotes |
IKK1 |
| T8342 |
17680-17683 |
Protein |
denotes |
NIK |
| T8343 |
17781-17785 |
Protein |
denotes |
IKK1 |
| T9415 |
17941-17944 |
Protein |
denotes |
A20 |
| T9416 |
17953-17956 |
Protein |
denotes |
A20 |
| T9417 |
17972-17979 |
Protein |
denotes |
TNFAIP3 |
| T9418 |
17986-18011 |
Protein |
denotes |
ubiquitin-editing protein |
| T9419 |
18038-18043 |
Protein |
denotes |
NF-κB |
| T9420 |
18132-18135 |
Protein |
denotes |
TNF |
| T9421 |
18275-18278 |
Protein |
denotes |
A20 |
| T9422 |
18382-18386 |
Protein |
denotes |
RIP1 |
| T9423 |
18388-18392 |
Protein |
denotes |
RIP2 |
| T9424 |
18394-18399 |
Protein |
denotes |
TRAF6 |
| T9425 |
18404-18409 |
Protein |
denotes |
MALT1 |
| T9477 |
18417-18425 |
Negative_regulation |
denotes |
disrupts |
| T9478 |
18451-18463 |
Binding |
denotes |
interactions |
| T9479 |
18498-18508 |
Negative_regulation |
denotes |
disruption |
| T9480 |
18512-18524 |
Binding |
denotes |
interactions |
| T9426 |
18567-18572 |
Protein |
denotes |
Ubc13 |
| T9427 |
18577-18583 |
Protein |
denotes |
Ubc5hc |
| T9428 |
18611-18616 |
Protein |
denotes |
TRAF6 |
| T9429 |
18618-18623 |
Protein |
denotes |
TRAF2 |
| T9430 |
18628-18633 |
Protein |
denotes |
cIAP1 |
| T9431 |
18634-18635 |
Protein |
denotes |
2 |
| T9432 |
18691-18694 |
Protein |
denotes |
A20 |
| T9481 |
18738-18749 |
Binding |
denotes |
association |
| T9433 |
18753-18756 |
Protein |
denotes |
A20 |
| T9434 |
18838-18877 |
Protein |
denotes |
A20-binding inhibitor of NF-κB (ABIN) 1 |
| T9482 |
18850-18859 |
Negative_regulation |
denotes |
inhibitor |
| T9435 |
18882-18904 |
Protein |
denotes |
Tax1-binding protein 1 |
| T9436 |
18964-18967 |
Protein |
denotes |
A20 |
| T9437 |
19062-19065 |
Protein |
denotes |
A20 |
| T9438 |
19126-19129 |
Protein |
denotes |
A20 |
| T9483 |
19130-19139 |
Negative_regulation |
denotes |
deficient |
| T9439 |
19311-19314 |
Protein |
denotes |
A20 |
| T9484 |
19315-19324 |
Negative_regulation |
denotes |
deficient |
| T9440 |
19360-19363 |
Protein |
denotes |
TNF |
| T9485 |
19475-19482 |
Negative_regulation |
denotes |
lacking |
| T9441 |
19483-19486 |
Protein |
denotes |
A20 |
| T9442 |
19643-19646 |
Protein |
denotes |
TNF |
| T9443 |
19677-19680 |
Protein |
denotes |
A20 |
| T9486 |
19790-19797 |
Negative_regulation |
denotes |
lacking |
| T9444 |
19798-19801 |
Protein |
denotes |
A20 |
| T9445 |
19929-19932 |
Protein |
denotes |
A20 |
| T9487 |
19933-19943 |
Gene_expression |
denotes |
expression |
| T9446 |
20106-20109 |
Protein |
denotes |
A20 |
| T9488 |
20110-20120 |
Gene_expression |
denotes |
expression |
| T9489 |
20131-20140 |
Regulation |
denotes |
regulated |
| T9447 |
20168-20171 |
Protein |
denotes |
A20 |
| T9448 |
20271-20274 |
Protein |
denotes |
A20 |
| T9490 |
20275-20285 |
Gene_expression |
denotes |
expressing |
| T9449 |
20499-20502 |
Protein |
denotes |
A20 |
| T9491 |
20503-20513 |
Gene_expression |
denotes |
expression |
| T9492 |
20586-20595 |
Negative_regulation |
denotes |
decreased |
| T9450 |
20606-20609 |
Protein |
denotes |
TNF |
| T9451 |
20611-20616 |
Protein |
denotes |
IL-1β |
| T9452 |
20618-20622 |
Protein |
denotes |
IL-6 |
| T9453 |
20632-20637 |
Protein |
denotes |
RANKL |
| T9454 |
20639-20674 |
Protein |
denotes |
monocyte chemo-attractant protein 1 |
| T9455 |
20703-20706 |
Protein |
denotes |
A20 |
| T9456 |
20861-20864 |
Protein |
denotes |
TNF |
| T9457 |
20869-20874 |
Protein |
denotes |
IL-1β |
| T9493 |
20888-20895 |
Positive_regulation |
denotes |
mediate |
| T9494 |
20970-20979 |
Negative_regulation |
denotes |
decreased |
| T9458 |
20996-20999 |
Protein |
denotes |
TNF |
| T9459 |
21004-21009 |
Protein |
denotes |
IL-1β |
| T9460 |
21013-21016 |
Protein |
denotes |
A20 |
| T9461 |
21162-21165 |
Protein |
denotes |
A20 |
| T9462 |
21257-21260 |
Protein |
denotes |
A20 |
| T9495 |
21456-21460 |
Negative_regulation |
denotes |
lack |
| T9463 |
21461-21464 |
Protein |
denotes |
A20 |
| T9464 |
21607-21610 |
Protein |
denotes |
A20 |
| T9465 |
21828-21831 |
Protein |
denotes |
A20 |
| T9466 |
21982-21985 |
Protein |
denotes |
A20 |
| T9467 |
22029-22032 |
Protein |
denotes |
A20 |
| T9468 |
22116-22119 |
Protein |
denotes |
A20 |
| T9469 |
22151-22154 |
Protein |
denotes |
TNF |
| T9470 |
22176-22179 |
Protein |
denotes |
TNF |
| T9471 |
22208-22216 |
Protein |
denotes |
cytokine |
| T9472 |
22246-22249 |
Protein |
denotes |
A20 |
| T9473 |
22327-22330 |
Protein |
denotes |
A20 |
| T9474 |
22507-22510 |
Protein |
denotes |
A20 |
| T9496 |
22545-22554 |
Negative_regulation |
denotes |
repressed |
| T9475 |
22555-22558 |
Protein |
denotes |
A20 |
| T9476 |
22791-22794 |
Protein |
denotes |
A20 |
| T12513 |
22866-22869 |
Protein |
denotes |
A20 |
| T12514 |
22898-22904 |
Protein |
denotes |
ABIN-1 |
| T12515 |
22906-22912 |
Protein |
denotes |
ABIN-2 |
| T12516 |
22917-22923 |
Protein |
denotes |
ABIN-3 |
| T12517 |
22939-22945 |
Protein |
denotes |
TNIP-1 |
| T12518 |
22947-22953 |
Protein |
denotes |
TNIP-2 |
| T12519 |
22959-22965 |
Protein |
denotes |
TNIP-3 |
| T12544 |
22999-23008 |
Gene_expression |
denotes |
expressed |
| T12520 |
23009-23012 |
Protein |
denotes |
A20 |
| T12545 |
23052-23059 |
Negative_regulation |
denotes |
inhibit |
| T12546 |
23066-23076 |
Positive_regulation |
denotes |
activation |
| T12521 |
23080-23083 |
Protein |
denotes |
TNF |
| T12547 |
23128-23142 |
Positive_regulation |
denotes |
overexpression |
| T12548 |
23229-23235 |
Binding |
denotes |
target |
| T12522 |
23236-23239 |
Protein |
denotes |
A20 |
| T12523 |
23292-23295 |
Protein |
denotes |
A20 |
| T12524 |
23297-23303 |
Protein |
denotes |
ABIN-1 |
| T12525 |
23308-23314 |
Protein |
denotes |
ABIN-3 |
| T12549 |
23315-23325 |
Gene_expression |
denotes |
expression |
| T12550 |
23370-23374 |
Regulation |
denotes |
role |
| T12526 |
23383-23386 |
Protein |
denotes |
A20 |
| T12527 |
23495-23501 |
Protein |
denotes |
ABIN-1 |
| T12551 |
23502-23511 |
Negative_regulation |
denotes |
deficient |
| T12528 |
23516-23522 |
Protein |
denotes |
ABIN-2 |
| T12552 |
23523-23532 |
Negative_regulation |
denotes |
deficient |
| T12529 |
23707-23713 |
Protein |
denotes |
ABIN-3 |
| T12553 |
23717-23726 |
Gene_expression |
denotes |
expressed |
| T12554 |
23752-23759 |
Gene_expression |
denotes |
express |
| T12530 |
23762-23789 |
Protein |
denotes |
truncated and inactive form |
| T12555 |
23790-23797 |
Negative_regulation |
denotes |
lacking |
| T12531 |
23848-23851 |
Protein |
denotes |
A20 |
| T12532 |
23853-23859 |
Protein |
denotes |
ABIN-1 |
| T12556 |
23874-23882 |
Negative_regulation |
denotes |
inhibits |
| T12533 |
23883-23886 |
Protein |
denotes |
TNF |
| T12534 |
23915-23921 |
Protein |
denotes |
ABIN-1 |
| T12557 |
23922-23931 |
Negative_regulation |
denotes |
deficient |
| T12535 |
23962-23965 |
Protein |
denotes |
TNF |
| T12536 |
24048-24054 |
Protein |
denotes |
ABIN-1 |
| T12537 |
24076-24079 |
Protein |
denotes |
TNF |
| T12558 |
24080-24087 |
Positive_regulation |
denotes |
induced |
| T12559 |
24121-24125 |
Positive_regulation |
denotes |
high |
| T12538 |
24136-24142 |
Protein |
denotes |
ABIN-1 |
| T12560 |
24143-24147 |
Transcription |
denotes |
mRNA |
| T12561 |
24208-24212 |
Regulation |
denotes |
role |
| T12539 |
24217-24223 |
Protein |
denotes |
ABIN-1 |
| T12540 |
24239-24242 |
Protein |
denotes |
A20 |
| T12562 |
24482-24492 |
Gene_expression |
denotes |
expression |
| T12541 |
24526-24532 |
Protein |
denotes |
ABIN-3 |
| T12542 |
24537-24540 |
Protein |
denotes |
A20 |
| T12563 |
24568-24574 |
Regulation |
denotes |
effect |
| T12543 |
24679-24685 |
Protein |
denotes |
ABIN-1 |
| T14025 |
25238-25253 |
Protein |
denotes |
Cylindromatosis |
| T14026 |
25262-25277 |
Protein |
denotes |
Cylindromatosis |
| T14027 |
25279-25283 |
Protein |
denotes |
CYLD |
| T14028 |
25385-25389 |
Protein |
denotes |
CYLD |
| T14029 |
25578-25582 |
Protein |
denotes |
CYLD |
| T14030 |
25588-25611 |
Protein |
denotes |
deubiquitinating enzyme |
| T14031 |
25674-25678 |
Protein |
denotes |
RANK |
| T14032 |
25807-25811 |
Protein |
denotes |
NEMO |
| T14033 |
25813-25818 |
Protein |
denotes |
TRAF2 |
| T14034 |
25820-25825 |
Protein |
denotes |
TRAF6 |
| T14035 |
25827-25832 |
Protein |
denotes |
TRAF7 |
| T14036 |
25834-25838 |
Protein |
denotes |
RIP1 |
| T14037 |
25843-25847 |
Protein |
denotes |
TAK1 |
| T14038 |
25884-25887 |
Protein |
denotes |
A20 |
| T14039 |
25933-25936 |
Protein |
denotes |
A20 |
| T14040 |
25948-25952 |
Protein |
denotes |
CYLD |
| T14041 |
25985-25988 |
Protein |
denotes |
A20 |
| T14059 |
25997-26006 |
Gene_expression |
denotes |
expressed |
| T14042 |
26143-26147 |
Protein |
denotes |
CYLD |
| T14043 |
26290-26294 |
Protein |
denotes |
CYLD |
| T14044 |
26333-26337 |
Protein |
denotes |
RANK |
| T14045 |
26420-26424 |
Protein |
denotes |
CYLD |
| T14046 |
26559-26564 |
Protein |
denotes |
RANKL |
| T14060 |
26593-26600 |
Gene_expression |
denotes |
produce |
| T14047 |
26630-26634 |
Protein |
denotes |
CYLD |
| T14061 |
26635-26645 |
Gene_expression |
denotes |
expression |
| T14048 |
26690-26695 |
Protein |
denotes |
RANKL |
| T14062 |
26696-26703 |
Positive_regulation |
denotes |
induced |
| T14063 |
26730-26739 |
Binding |
denotes |
recruited |
| T14049 |
26757-26762 |
Protein |
denotes |
TRAF6 |
| T14064 |
26763-26766 |
Positive_regulation |
denotes |
via |
| T14050 |
26771-26780 |
Protein |
denotes |
ubiquitin |
| T14051 |
26805-26808 |
Protein |
denotes |
p62 |
| T14052 |
26824-26838 |
Protein |
denotes |
sequestosome 1 |
| T14053 |
26862-26866 |
Protein |
denotes |
CYLD |
| T14054 |
26896-26901 |
Protein |
denotes |
TRAF6 |
| T14055 |
26993-26996 |
Protein |
denotes |
p62 |
| T14056 |
27106-27110 |
Protein |
denotes |
CYLD |
| T14057 |
27135-27139 |
Protein |
denotes |
RANK |
| T14058 |
27244-27248 |
Protein |
denotes |
CYLD |
| T15419 |
27336-27379 |
Protein |
denotes |
Single-immunoglobulin IL-1 receptor-related |
| T15420 |
27388-27431 |
Protein |
denotes |
Single-immunoglobulin IL-1 receptor-related |
| T15421 |
27433-27439 |
Protein |
denotes |
SIGIRR |
| T15422 |
27464-27469 |
Protein |
denotes |
TIR-8 |
| T15436 |
27553-27562 |
Negative_regulation |
denotes |
inhibitor |
| T15423 |
27566-27571 |
Protein |
denotes |
IL-1R |
| T15437 |
27616-27627 |
Binding |
denotes |
interaction |
| T15424 |
27650-27655 |
Protein |
denotes |
MyD88 |
| T15425 |
27657-27662 |
Protein |
denotes |
IRAK1 |
| T15426 |
27666-27671 |
Protein |
denotes |
TRAF6 |
| T15427 |
27717-27722 |
Protein |
denotes |
IL-1R |
| T15428 |
27813-27819 |
Protein |
denotes |
SIGIRR |
| T15429 |
27843-27849 |
Protein |
denotes |
SIGIRR |
| T15438 |
27898-27907 |
Gene_expression |
denotes |
expressed |
| T15430 |
28019-28025 |
Protein |
denotes |
SIGIRR |
| T15431 |
28168-28174 |
Protein |
denotes |
SIGIRR |
| T15432 |
28212-28218 |
Protein |
denotes |
SIGIRR |
| T15439 |
28219-28228 |
Negative_regulation |
denotes |
deficient |
| T15440 |
28391-28401 |
Gene_expression |
denotes |
expression |
| T15433 |
28405-28411 |
Protein |
denotes |
SIGIRR |
| T15441 |
28436-28446 |
Gene_expression |
denotes |
expression |
| T15434 |
28510-28516 |
Protein |
denotes |
SIGIRR |
| T15442 |
28574-28584 |
Gene_expression |
denotes |
expression |
| T15435 |
28594-28600 |
Protein |
denotes |
SIGIRR |
| T16285 |
28655-28687 |
Protein |
denotes |
TNF receptor-associated factor 1 |
| T16286 |
28688-28693 |
Protein |
denotes |
TRAF1 |
| T16287 |
28798-28807 |
Protein |
denotes |
ubiquitin |
| T16288 |
28862-28867 |
Protein |
denotes |
TRAF1 |
| T16306 |
29015-29025 |
Gene_expression |
denotes |
Expression |
| T16289 |
29029-29034 |
Protein |
denotes |
TRAF1 |
| T16307 |
29038-29047 |
Positive_regulation |
denotes |
inducible |
| T16290 |
29051-29054 |
Protein |
denotes |
TNF |
| T16308 |
29059-29073 |
Positive_regulation |
denotes |
overexpression |
| T16291 |
29077-29082 |
Protein |
denotes |
TRAF1 |
| T16292 |
29092-29095 |
Protein |
denotes |
TNF |
| T16309 |
29110-29120 |
Positive_regulation |
denotes |
activation |
| T16293 |
29122-29127 |
Protein |
denotes |
TRAF1 |
| T16310 |
29128-29137 |
Negative_regulation |
denotes |
deficient |
| T16294 |
29170-29173 |
Protein |
denotes |
TNF |
| T16295 |
29251-29256 |
Protein |
denotes |
TRAF1 |
| T16296 |
29299-29303 |
Protein |
denotes |
CD40 |
| T16297 |
29330-29335 |
Protein |
denotes |
TRAF1 |
| T16311 |
29336-29345 |
Negative_regulation |
denotes |
deficient |
| T16298 |
29426-29431 |
Protein |
denotes |
TRAF2 |
| T16299 |
29528-29533 |
Protein |
denotes |
TRAF1 |
| T16300 |
29595-29600 |
Protein |
denotes |
TRAF1 |
| T16312 |
29639-29646 |
Binding |
denotes |
binding |
| T16301 |
29708-29713 |
Protein |
denotes |
TRAF1 |
| T16313 |
29720-29727 |
Binding |
denotes |
recruit |
| T16302 |
29728-29731 |
Protein |
denotes |
A20 |
| T16314 |
29761-29769 |
Binding |
denotes |
interact |
| T16303 |
29955-29960 |
Protein |
denotes |
TRAF1 |
| T16304 |
30057-30062 |
Protein |
denotes |
TRAF1 |
| T16305 |
30190-30195 |
Protein |
denotes |
TRAF1 |
| T17346 |
30444-30448 |
Binding |
denotes |
bind |
| T17316 |
30575-30583 |
Protein |
denotes |
miR-146a |
| T17317 |
30584-30585 |
Protein |
denotes |
b |
| T17318 |
30590-30597 |
Protein |
denotes |
miR-155 |
| T17347 |
30689-30696 |
Positive_regulation |
denotes |
induced |
| T17319 |
30729-30734 |
Protein |
denotes |
IL-1β |
| T17320 |
30736-30739 |
Protein |
denotes |
TNF |
| T17321 |
30771-30779 |
Protein |
denotes |
miR-146a |
| T17322 |
30843-30848 |
Protein |
denotes |
IRAK1 |
| T17323 |
30853-30858 |
Protein |
denotes |
TRAF6 |
| T17324 |
30894-30902 |
Protein |
denotes |
miR-146a |
| T17325 |
30931-30938 |
Protein |
denotes |
miR-155 |
| T17348 |
30952-30958 |
Binding |
denotes |
target |
| T17326 |
31006-31010 |
Protein |
denotes |
IKKε |
| T17327 |
31015-31019 |
Protein |
denotes |
RIP1 |
| T17328 |
31055-31062 |
Protein |
denotes |
miR-155 |
| T17349 |
31067-31076 |
Gene_expression |
denotes |
expressed |
| T17329 |
31220-31228 |
Protein |
denotes |
miR-146a |
| T17350 |
31237-31250 |
Gene_expression |
denotes |
overexpressed |
| T17330 |
31254-31257 |
Protein |
denotes |
CD4 |
| T17331 |
31263-31268 |
Protein |
denotes |
IL-17 |
| T17351 |
31269-31278 |
Gene_expression |
denotes |
producing |
| T17332 |
31364-31372 |
Protein |
denotes |
miR-146a |
| T17333 |
31450-31457 |
Protein |
denotes |
miR-155 |
| T17352 |
31458-31472 |
Positive_regulation |
denotes |
overexpression |
| T17353 |
31509-31516 |
Negative_regulation |
denotes |
prevent |
| T17334 |
31651-31658 |
Protein |
denotes |
miR-155 |
| T17354 |
31672-31679 |
Positive_regulation |
denotes |
promote |
| T17335 |
31680-31683 |
Protein |
denotes |
TNF |
| T17355 |
31684-31694 |
Gene_expression |
denotes |
production |
| T17336 |
31754-31761 |
Protein |
denotes |
miR-155 |
| T17356 |
31934-31944 |
Gene_expression |
denotes |
expression |
| T17337 |
32152-32159 |
Protein |
denotes |
miR-155 |
| T17338 |
32324-32332 |
Protein |
denotes |
miR-124a |
| T17357 |
32341-32350 |
Regulation |
denotes |
regulator |
| T17339 |
32368-32402 |
Protein |
denotes |
monocyte chemoattractant protein 1 |
| T17358 |
32481-32489 |
Positive_regulation |
denotes |
elevated |
| T17340 |
32500-32507 |
Protein |
denotes |
miR-203 |
| T17359 |
32521-32530 |
Positive_regulation |
denotes |
increased |
| T17360 |
32531-32540 |
Localization |
denotes |
secretion |
| T17341 |
32544-32570 |
Protein |
denotes |
matrix metalloproteinase-1 |
| T17342 |
32575-32579 |
Protein |
denotes |
IL-6 |
| T17343 |
32638-32644 |
Protein |
denotes |
miR-16 |
| T17344 |
32646-32653 |
Protein |
denotes |
miR-132 |
| T17345 |
32659-32666 |
Protein |
denotes |
miR-223 |
| T17361 |
32702-32712 |
Gene_expression |
denotes |
expression |
| R10157 |
T15421 |
T15420 |
equivalentTo |
SIGIRR,Single-immunoglobulin IL-1 receptor-related |
| R10158 |
T15423 |
T15436 |
themeOf |
IL-1R,inhibitor |
| R10159 |
T15423 |
T15437 |
themeOf |
IL-1R,interaction |
| R10160 |
T15424 |
T15437 |
themeOf |
MyD88,interaction |
| R10161 |
T15425 |
T15437 |
themeOf |
IRAK1,interaction |
| R10162 |
T15426 |
T15437 |
themeOf |
TRAF6,interaction |
| R10163 |
T15429 |
T15438 |
themeOf |
SIGIRR,expressed |
| R10164 |
T15432 |
T15439 |
themeOf |
SIGIRR,deficient |
| R10165 |
T15433 |
T15440 |
themeOf |
SIGIRR,expression |
| R10166 |
T15435 |
T15442 |
themeOf |
SIGIRR,expression |
| R10748 |
T16289 |
T16306 |
themeOf |
TRAF1,Expression |
| R10749 |
T16290 |
T16307 |
causeOf |
TNF,inducible |
| R10750 |
T16291 |
T16308 |
themeOf |
TRAF1,overexpression |
| R10751 |
T16293 |
T16310 |
themeOf |
TRAF1,deficient |
| R10752 |
T16297 |
T16311 |
themeOf |
TRAF1,deficient |
| R10753 |
T16300 |
T16312 |
themeOf |
TRAF1,binding |
| R10754 |
T16301 |
T16314 |
themeOf |
TRAF1,interact |
| R10755 |
T16301 |
T16313 |
themeOf |
TRAF1,recruit |
| R10756 |
T16302 |
T16313 |
themeOf |
A20,recruit |
| R10757 |
T16302 |
T16314 |
themeOf |
A20,interact |
| R10758 |
T16306 |
T16307 |
themeOf |
Expression,inducible |
| R11370 |
T17316 |
T17347 |
themeOf |
miR-146a,induced |
| R11371 |
T17318 |
T17347 |
themeOf |
miR-155,induced |
| R11372 |
T17319 |
T17347 |
causeOf |
IL-1β,induced |
| R11373 |
T17320 |
T17347 |
causeOf |
TNF,induced |
| R11374 |
T17325 |
T17348 |
themeOf |
miR-155,target |
| R11375 |
T17326 |
T17348 |
themeOf |
IKKε,target |
| R11376 |
T17327 |
T17348 |
themeOf |
RIP1,target |
| R11377 |
T17328 |
T17349 |
themeOf |
miR-155,expressed |
| R11378 |
T17329 |
T17350 |
themeOf |
miR-146a,overexpressed |
| R11379 |
T17331 |
T17351 |
themeOf |
IL-17,producing |
| R11380 |
T17333 |
T17352 |
themeOf |
miR-155,overexpression |
| R11381 |
T17334 |
T17354 |
causeOf |
miR-155,promote |
| R11382 |
T17335 |
T17355 |
themeOf |
TNF,production |
| R11383 |
T17338 |
T17357 |
causeOf |
miR-124a,regulator |
| R11384 |
T17339 |
T17357 |
themeOf |
monocyte chemoattractant protein 1,regulator |
| R11385 |
T17341 |
T17360 |
themeOf |
matrix metalloproteinase-1,secretion |
| R11386 |
T17342 |
T17360 |
themeOf |
IL-6,secretion |
| R11387 |
T17343 |
T17361 |
themeOf |
miR-16,expression |
| R11388 |
T17344 |
T17361 |
themeOf |
miR-132,expression |
| R11389 |
T17345 |
T17361 |
themeOf |
miR-223,expression |
| R11390 |
T17355 |
T17354 |
themeOf |
production,promote |
| R11391 |
T17360 |
T17359 |
themeOf |
secretion,increased |
| R1266 |
T1644 |
T1643 |
equivalentTo |
RANK,receptor activator of NF-κB |
| R1267 |
T1646 |
T1670 |
themeOf |
CD40,expressed |
| R1268 |
T1647 |
T1670 |
themeOf |
TNF receptor family member,expressed |
| R1269 |
T1648 |
T1671 |
causeOf |
TNF,upregulated |
| R1270 |
T1649 |
T1672 |
themeOf |
CD40 ligand,Binding |
| R1271 |
T1649 |
T1673 |
themeOf |
CD40 ligand,expressed |
| R1272 |
T1650 |
T1649 |
equivalentTo |
CD154,CD40 ligand |
| R1273 |
T1653 |
T1675 |
themeOf |
B-cell activating factor,expression |
| R1274 |
T1654 |
T1653 |
equivalentTo |
BAFF,B-cell activating factor |
| R12749 |
T19260 |
T19316 |
themeOf |
TNFR1,engagement |
| R1275 |
T1657 |
T1659 |
themeOf |
High mobility group box chromosomal protein 1,chromatin component |
| R12750 |
T19261 |
T19316 |
themeOf |
CD40,engagement |
| R12751 |
T19262 |
T19316 |
themeOf |
RANK,engagement |
| R12752 |
T19263 |
T19317 |
causeOf |
TLR4,trigger |
| R12753 |
T19263 |
T19316 |
themeOf |
TLR4,engagement |
| R12754 |
T19264 |
T19318 |
themeOf |
TNF receptor 1-associated death domain protein,recruitment |
| R12755 |
T19266 |
T19318 |
themeOf |
MyD88,recruitment |
| R12756 |
T19267 |
T19318 |
themeOf |
MAL,recruitment |
| R12757 |
T19268 |
T19318 |
themeOf |
TIR domain-containing adaptor-inducing IFNβ,recruitment |
| R12758 |
T19269 |
T19268 |
equivalentTo |
TRIF,TIR domain-containing adaptor-inducing IFNβ |
| R12759 |
T19270 |
T19268 |
equivalentTo |
RIP1,TIR domain-containing adaptor-inducing IFNβ |
| R1276 |
T1657 |
T1678 |
themeOf |
High mobility group box chromosomal protein 1,released |
| R12760 |
T19271 |
T19318 |
themeOf |
IRAK1,recruitment |
| R12761 |
T19272 |
T19318 |
themeOf |
IRAK4,recruitment |
| R12762 |
T19273 |
T19268 |
equivalentTo |
TRAF2,TIR domain-containing adaptor-inducing IFNβ |
| R12763 |
T19274 |
T19318 |
themeOf |
TRAF6,recruitment |
| R12764 |
T19275 |
T19318 |
themeOf |
cIAP1,recruitment |
| R12765 |
T19276 |
T19318 |
themeOf |
cIAP2,recruitment |
| R12766 |
T19283 |
T19321 |
themeOf |
IKK2,degradation |
| R12767 |
T19284 |
T19320 |
themeOf |
IκBα,phosphorylates |
| R12768 |
T19285 |
T19322 |
themeOf |
p65,translocate |
| R12769 |
T19286 |
T19322 |
themeOf |
p50,translocate |
| R1277 |
T1657 |
T1677 |
themeOf |
High mobility group box chromosomal protein 1,secreted |
| R12770 |
T19290 |
T19324 |
themeOf |
RIP1,recruited |
| R12771 |
T19291 |
T19324 |
themeOf |
TRAF6,recruited |
| R12772 |
T19292 |
T19324 |
themeOf |
ABIN-1,recruited |
| R12773 |
T19293 |
T19324 |
themeOf |
p62,recruited |
| R12774 |
T19294 |
T19327 |
themeOf |
IRAK1,expression |
| R12775 |
T19295 |
T19327 |
themeOf |
TRAF6,expression |
| R12776 |
T19296 |
T19328 |
causeOf |
SIGIRR,inhibited |
| R12777 |
T19297 |
T19330 |
themeOf |
TLR4,binding |
| R12778 |
T19298 |
T19330 |
themeOf |
IRAK1,binding |
| R12779 |
T19299 |
T19330 |
themeOf |
TRAF6,binding |
| R1278 |
T1658 |
T1657 |
equivalentTo |
HMGB1,High mobility group box chromosomal protein 1 |
| R12780 |
T19304 |
T19331 |
themeOf |
MyD88,inhibitor |
| R12781 |
T19305 |
T19331 |
themeOf |
myeloid differentiation primary response gene 88,inhibitor |
| R12782 |
T19306 |
T19331 |
themeOf |
NEMO,inhibitor |
| R12783 |
T19307 |
T19331 |
themeOf |
NF-κB essential modulator,inhibitor |
| R12784 |
T19308 |
T19331 |
themeOf |
RANK,inhibitor |
| R12785 |
T19309 |
T19331 |
themeOf |
receptor activator of NF-κB,inhibitor |
| R12786 |
T19309 |
T19308 |
themeOf |
receptor activator of NF-κB,RANK |
| R12787 |
T19310 |
T19331 |
themeOf |
RIP1,inhibitor |
| R12788 |
T19311 |
T19331 |
themeOf |
receptor interacting protein 1,inhibitor |
| R12789 |
T19312 |
T19331 |
themeOf |
SIGIRR,inhibitor |
| R1279 |
T1659 |
T1677 |
themeOf |
chromatin component,secreted |
| R12790 |
T19313 |
T19331 |
themeOf |
single-immunoglobulinIL-1 receptor-related,inhibitor |
| R12791 |
T19314 |
T19308 |
themeOf |
TNF,RANK |
| R12792 |
T19314 |
T19331 |
themeOf |
TNF,inhibitor |
| R12793 |
T19315 |
T19331 |
themeOf |
tumour necrosis factor,inhibitor |
| R12794 |
T19318 |
T19317 |
themeOf |
recruitment,trigger |
| R12795 |
T19319 |
T19317 |
themeOf |
inducing,trigger |
| R12796 |
T19323 |
T19322 |
locationOf |
nucleus,translocate |
| R12797 |
T19327 |
T19326 |
themeOf |
expression,inhibiting |
| R12798 |
T19330 |
T19329 |
themeOf |
binding,compete |
| R1280 |
T1661 |
T1679 |
themeOf |
HMGB1,increased |
| R1281 |
T1670 |
T1671 |
themeOf |
expressed,upregulated |
| R13906 |
T21285 |
T21317 |
themeOf |
NF-κB inducing kinase,expression |
| R13907 |
T21286 |
T21285 |
equivalentTo |
NIK,NF-κB inducing kinase |
| R13908 |
T21292 |
T21318 |
themeOf |
NIK,degradation |
| R13909 |
T21294 |
T21319 |
themeOf |
TRAF3,recruited |
| R13910 |
T21304 |
T21320 |
themeOf |
NIK,increased |
| R13911 |
T21305 |
T21321 |
themeOf |
NIK,phosphorylates |
| R13912 |
T21306 |
T21321 |
themeOf |
IKK1,phosphorylates |
| R13913 |
T21306 |
T21322 |
causeOf |
IKK1,mediates |
| R13914 |
T21307 |
T21323 |
themeOf |
p100,phosphorylation |
| R13915 |
T21308 |
T21324 |
themeOf |
p100,degradation |
| R13916 |
T21309 |
T21324 |
themeOf |
p52,degradation |
| R13917 |
T21323 |
T21322 |
themeOf |
phosphorylation,mediates |
| R206 |
T261 |
T278 |
causeOf |
p105,regulate |
| R207 |
T264 |
T278 |
causeOf |
RelA,regulate |
| R208 |
T265 |
T278 |
causeOf |
RelB,regulate |
| R209 |
T266 |
T278 |
causeOf |
c-Rel,regulate |
| R210 |
T267 |
T279 |
themeOf |
TNF,expression |
| R211 |
T268 |
T279 |
themeOf |
IL-6,expression |
| R212 |
T269 |
T279 |
themeOf |
cyclo-oxygenase-2,expression |
| R213 |
T270 |
T279 |
themeOf |
inducible nitric oxide synthase,expression |
| R214 |
T273 |
T272 |
equivalentTo |
RANKL,receptor activator of NF-κB ligand |
| R215 |
T274 |
T280 |
themeOf |
CD40,association |
| R216 |
T275 |
T280 |
themeOf |
TRAF1,association |
| R217 |
T276 |
T280 |
themeOf |
TNFAIP3,association |
| R218 |
T277 |
T280 |
themeOf |
c-REL,association |
| R219 |
T279 |
T278 |
themeOf |
expression,regulate |
| R2776 |
T3847 |
T3954 |
themeOf |
IκBξ,inhibitors |
| R2777 |
T3848 |
T3954 |
themeOf |
Bcl-3,inhibitors |
| R2778 |
T3867 |
T3957 |
themeOf |
TNF receptor-1-associated death domain,recruitment |
| R2779 |
T3868 |
T3867 |
equivalentTo |
TRADD,TNF receptor-1-associated death domain |
| R2780 |
T3869 |
T3957 |
themeOf |
receptor interacting protein 1,recruitment |
| R2781 |
T3870 |
T3867 |
equivalentTo |
RIP1,TNF receptor-1-associated death domain |
| R2782 |
T3870 |
T3869 |
equivalentTo |
RIP1,receptor interacting protein 1 |
| R2783 |
T3871 |
T3958 |
themeOf |
TNF receptor-associated factor (TRAF) 2,bind |
| R2784 |
T3872 |
T3958 |
themeOf |
TRAF5,bind |
| R2785 |
T3873 |
T3958 |
themeOf |
cellular inhibitor of apoptosis (cIAP) 1,bind |
| R2786 |
T3874 |
T3958 |
themeOf |
cIAP2,bind |
| R2787 |
T3876 |
T3959 |
themeOf |
RIP1,bound |
| R2788 |
T3883 |
T3960 |
themeOf |
TAK1,recruit |
| R2789 |
T3890 |
T3963 |
causeOf |
TLR4,induces |
| R2790 |
T3891 |
T3964 |
themeOf |
Toll/IL-1 receptor adaptor protein,recruitment |
| R2791 |
T3893 |
T3964 |
themeOf |
TRIF-related adaptor molecule,recruitment |
| R2792 |
T3894 |
T3893 |
equivalentTo |
TRAM,TRIF-related adaptor molecule |
| R2793 |
T3896 |
T3895 |
equivalentTo |
MyD88,myeloid differentiation primary response gene 88 |
| R2794 |
T3898 |
T3897 |
equivalentTo |
TRIF,TIR domain-containing adaptor-inducing IFNβ |
| R2795 |
T3901 |
T3966 |
themeOf |
TRAF6,selfubiquitination |
| R2796 |
T3902 |
T3968 |
themeOf |
TRIF,interaction |
| R2797 |
T3902 |
T3967 |
themeOf |
TRIF,recruits |
| R2798 |
T3903 |
T3968 |
themeOf |
TRAF6,interaction |
| R2799 |
T3903 |
T3967 |
themeOf |
TRAF6,recruits |
| R2800 |
T3904 |
T3968 |
themeOf |
RIP1,interaction |
| R2801 |
T3904 |
T3967 |
themeOf |
RIP1,recruits |
| R2802 |
T3905 |
T3969 |
themeOf |
TAK1,activate |
| R2803 |
T3911 |
T3970 |
themeOf |
p100,phosphorylation |
| R2804 |
T3915 |
T3970 |
causeOf |
NF-κB inducing kinase,phosphorylation |
| R2805 |
T3916 |
T3915 |
equivalentTo |
NIK,NF-κB inducing kinase |
| R2806 |
T3918 |
T3973 |
themeOf |
NIK,degradation |
| R2807 |
T3919 |
T3973 |
themeOf |
TRAF2,degradation |
| R2808 |
T3920 |
T3973 |
themeOf |
TRAF3,degradation |
| R2809 |
T3921 |
T3973 |
themeOf |
cIAP1,degradation |
| R2810 |
T3922 |
T3973 |
themeOf |
2,degradation |
| R2811 |
T3923 |
T3973 |
themeOf |
NIK,degradation |
| R2812 |
T3928 |
T3974 |
themeOf |
TRAF3,degradation |
| R2813 |
T3931 |
T3976 |
themeOf |
IKK1,phosphorylation |
| R2814 |
T3935 |
T3978 |
themeOf |
CD40,interact |
| R2815 |
T3935 |
T3977 |
themeOf |
CD40,binding |
| R2816 |
T3936 |
T3978 |
themeOf |
RANK,interact |
| R2817 |
T3937 |
T3978 |
themeOf |
TRAF1,interact |
| R2818 |
T3938 |
T3977 |
themeOf |
TRAF2,binding |
| R2819 |
T3938 |
T3978 |
themeOf |
TRAF2,interact |
| R2820 |
T3939 |
T3977 |
themeOf |
TRAF3,binding |
| R2821 |
T3939 |
T3978 |
themeOf |
TRAF3,interact |
| R2822 |
T3940 |
T3978 |
themeOf |
TRAF5,interact |
| R2823 |
T3940 |
T3977 |
themeOf |
TRAF5,binding |
| R2824 |
T3941 |
T3977 |
themeOf |
TRAF6,binding |
| R2825 |
T3941 |
T3978 |
themeOf |
TRAF6,interact |
| R2826 |
T3942 |
T3980 |
themeOf |
TRAF2,proteolysis |
| R2827 |
T3943 |
T3980 |
themeOf |
TRAF3,proteolysis |
| R2828 |
T3945 |
T3981 |
causeOf |
TRAF6,required |
| R2829 |
T3946 |
T3982 |
causeOf |
CD40,mediated |
| R2830 |
T3947 |
T3983 |
themeOf |
IL-6,production |
| R2831 |
T3952 |
T3953 |
locationOf |
nuclear,translocation |
| R2832 |
T3953 |
T3951 |
themeOf |
translocation,prevent |
| R2833 |
T3961 |
T3962 |
themeOf |
ubiquitin-,binding |
| R2834 |
T3964 |
T3963 |
themeOf |
recruitment,induces |
| R2835 |
T3972 |
T3971 |
themeOf |
-translational,regulated |
| R2836 |
T3977 |
T3979 |
causeOf |
binding,leads |
| R2837 |
T3978 |
T3979 |
causeOf |
interact,leads |
| R2838 |
T3980 |
T3979 |
themeOf |
proteolysis,leads |
| R2839 |
T3982 |
T3981 |
themeOf |
mediated,required |
| R2840 |
T3983 |
T3982 |
themeOf |
production,mediated |
| R5567 |
T8335 |
T8344 |
themeOf |
IKK1,deficient |
| R5568 |
T8336 |
T8345 |
themeOf |
IKK1,expressing |
| R5569 |
T8338 |
T8347 |
themeOf |
IκBα,degradation |
| R5570 |
T8347 |
T8346 |
themeOf |
degradation,enhanced |
| R6327 |
T9421 |
T9477 |
causeOf |
A20,disrupts |
| R6328 |
T9423 |
T9477 |
causeOf |
RIP2,disrupts |
| R6329 |
T9424 |
T9477 |
causeOf |
TRAF6,disrupts |
| R6330 |
T9425 |
T9477 |
causeOf |
MALT1,disrupts |
| R6331 |
T9427 |
T9480 |
themeOf |
Ubc5hc,interactions |
| R6332 |
T9429 |
T9480 |
themeOf |
TRAF2,interactions |
| R6333 |
T9430 |
T9480 |
themeOf |
cIAP1,interactions |
| R6334 |
T9431 |
T9480 |
themeOf |
2,interactions |
| R6335 |
T9433 |
T9481 |
themeOf |
A20,association |
| R6336 |
T9435 |
T9482 |
themeOf |
Tax1-binding protein 1,inhibitor |
| R6337 |
T9438 |
T9483 |
themeOf |
A20,deficient |
| R6338 |
T9439 |
T9484 |
themeOf |
A20,deficient |
| R6339 |
T9441 |
T9485 |
themeOf |
A20,lacking |
| R6340 |
T9444 |
T9486 |
themeOf |
A20,lacking |
| R6341 |
T9445 |
T9487 |
themeOf |
A20,expression |
| R6342 |
T9446 |
T9488 |
themeOf |
A20,expression |
| R6343 |
T9447 |
T9489 |
causeOf |
A20,regulated |
| R6344 |
T9448 |
T9490 |
themeOf |
A20,expressing |
| R6345 |
T9449 |
T9491 |
themeOf |
A20,expression |
| R6346 |
T9450 |
T9492 |
themeOf |
TNF,decreased |
| R6347 |
T9451 |
T9492 |
themeOf |
IL-1β,decreased |
| R6348 |
T9452 |
T9492 |
themeOf |
IL-6,decreased |
| R6349 |
T9453 |
T9492 |
themeOf |
RANKL,decreased |
| R6350 |
T9454 |
T9492 |
themeOf |
monocyte chemo-attractant protein 1,decreased |
| R6351 |
T9456 |
T9493 |
causeOf |
TNF,mediate |
| R6352 |
T9457 |
T9493 |
causeOf |
IL-1β,mediate |
| R6353 |
T9458 |
T9494 |
themeOf |
TNF,decreased |
| R6354 |
T9459 |
T9494 |
themeOf |
IL-1β,decreased |
| R6355 |
T9463 |
T9495 |
themeOf |
A20,lack |
| R6356 |
T9478 |
T9477 |
themeOf |
interactions,disrupts |
| R6357 |
T9480 |
T9479 |
themeOf |
interactions,disruption |
| R6358 |
T9488 |
T9489 |
themeOf |
expression,regulated |
| R8292 |
T12514 |
T12545 |
causeOf |
ABIN-1,inhibit |
| R8293 |
T12514 |
T12544 |
themeOf |
ABIN-1,expressed |
| R8294 |
T12514 |
T12547 |
themeOf |
ABIN-1,overexpression |
| R8295 |
T12515 |
T12544 |
themeOf |
ABIN-2,expressed |
| R8296 |
T12516 |
T12544 |
themeOf |
ABIN-3,expressed |
| R8297 |
T12517 |
T12544 |
themeOf |
TNIP-1,expressed |
| R8298 |
T12518 |
T12544 |
themeOf |
TNIP-2,expressed |
| R8299 |
T12520 |
T12544 |
themeOf |
A20,expressed |
| R8300 |
T12521 |
T12546 |
causeOf |
TNF,activation |
| R8301 |
T12522 |
T12548 |
themeOf |
A20,target |
| R8302 |
T12523 |
T12549 |
themeOf |
A20,expression |
| R8303 |
T12524 |
T12549 |
themeOf |
ABIN-1,expression |
| R8304 |
T12525 |
T12549 |
themeOf |
ABIN-3,expression |
| R8305 |
T12527 |
T12551 |
themeOf |
ABIN-1,deficient |
| R8306 |
T12527 |
T12552 |
themeOf |
ABIN-1,deficient |
| R8307 |
T12528 |
T12552 |
themeOf |
ABIN-2,deficient |
| R8308 |
T12529 |
T12554 |
themeOf |
ABIN-3,express |
| R8309 |
T12529 |
T12553 |
themeOf |
ABIN-3,expressed |
| R8310 |
T12532 |
T12556 |
causeOf |
ABIN-1,inhibits |
| R8311 |
T12534 |
T12557 |
themeOf |
ABIN-1,deficient |
| R8312 |
T12537 |
T12558 |
causeOf |
TNF,induced |
| R8313 |
T12541 |
T12562 |
themeOf |
ABIN-3,expression |
| R8314 |
T12542 |
T12562 |
themeOf |
A20,expression |
| R8315 |
T12546 |
T12545 |
themeOf |
activation,inhibit |
| R9294 |
T14027 |
T14026 |
equivalentTo |
CYLD,Cylindromatosis |
| R9295 |
T14041 |
T14059 |
themeOf |
A20,expressed |
| R9296 |
T14047 |
T14061 |
themeOf |
CYLD,expression |
| R9297 |
T14049 |
T14063 |
themeOf |
TRAF6,recruited |
| R9298 |
T14052 |
T14063 |
themeOf |
sequestosome 1,recruited |
| R9299 |
T14052 |
T14064 |
causeOf |
sequestosome 1,via |
| R9300 |
T14063 |
T14064 |
themeOf |
recruited,via |
