| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T39 |
4-13 |
Regulation |
denotes |
Regulates |
| T29 |
14-18 |
Protein |
denotes |
TNFα |
| T40 |
14-18 |
Protein |
denotes |
TNFα |
| T41 |
19-28 |
Gene_expression |
denotes |
Synthesis |
| T30 |
43-47 |
Protein |
denotes |
RIP1 |
| T42 |
43-47 |
Protein |
denotes |
RIP1 |
| T43 |
404-414 |
Regulation |
denotes |
controlled |
| T44 |
443-473 |
Protein |
denotes |
receptor interacting protein-1 |
| T31 |
443-473 |
Protein |
denotes |
receptor interacting protein-1 |
| T45 |
475-479 |
Protein |
denotes |
RIP1 |
| T32 |
475-479 |
Protein |
denotes |
RIP1 |
| T46 |
580-584 |
Regulation |
denotes |
role |
| T47 |
588-592 |
Protein |
denotes |
TNFα |
| T33 |
588-592 |
Protein |
denotes |
TNFα |
| T48 |
593-603 |
Gene_expression |
denotes |
production |
| T49 |
632-641 |
Positive_regulation |
denotes |
activated |
| T50 |
647-651 |
Protein |
denotes |
RIP1 |
| T34 |
647-651 |
Protein |
denotes |
RIP1 |
| T51 |
682-697 |
Phosphorylation |
denotes |
phosphorylation |
| T52 |
807-811 |
Protein |
denotes |
RIP1 |
| T35 |
807-811 |
Protein |
denotes |
RIP1 |
| T53 |
973-977 |
Protein |
denotes |
RIP1 |
| T36 |
973-977 |
Protein |
denotes |
RIP1 |
| T54 |
1010-1020 |
Gene_expression |
denotes |
production |
| T55 |
1024-1028 |
Protein |
denotes |
TNFα |
| T37 |
1024-1028 |
Protein |
denotes |
TNFα |
| T56 |
1149-1153 |
Protein |
denotes |
TNFα |
| T38 |
1149-1153 |
Protein |
denotes |
TNFα |
| T57 |
1154-1164 |
Gene_expression |
denotes |
production |
| T826 |
2132-2136 |
Protein |
denotes |
RIP1 |
| T845 |
2132-2136 |
Protein |
denotes |
RIP1 |
| T827 |
2141-2145 |
Protein |
denotes |
RIP3 |
| T846 |
2141-2145 |
Protein |
denotes |
RIP3 |
| T828 |
2757-2761 |
Protein |
denotes |
RIP1 |
| T847 |
2757-2761 |
Protein |
denotes |
RIP1 |
| T829 |
2766-2770 |
Protein |
denotes |
RIP3 |
| T848 |
2766-2770 |
Protein |
denotes |
RIP3 |
| T830 |
2964-2968 |
Protein |
denotes |
RIP1 |
| T849 |
2964-2968 |
Protein |
denotes |
RIP1 |
| T831 |
3015-3020 |
Protein |
denotes |
c-Jun |
| T850 |
3015-3020 |
Protein |
denotes |
c-Jun |
| T832 |
3180-3184 |
Protein |
denotes |
TNFα |
| T851 |
3180-3184 |
Protein |
denotes |
TNFα |
| T5186 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T5152 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T833 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T852 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T834 |
3352-3356 |
Protein |
denotes |
TNFα |
| T853 |
3352-3356 |
Protein |
denotes |
TNFα |
| T854 |
3357-3367 |
Gene_expression |
denotes |
production |
| T835 |
3627-3634 |
Protein |
denotes |
insulin |
| T855 |
3627-3634 |
Protein |
denotes |
insulin |
| T856 |
3635-3644 |
Regulation |
denotes |
dependent |
| T857 |
3645-3655 |
Positive_regulation |
denotes |
activation |
| T836 |
4106-4113 |
Protein |
denotes |
insulin |
| T858 |
4106-4113 |
Protein |
denotes |
insulin |
| T859 |
4204-4214 |
Positive_regulation |
denotes |
activation |
| T837 |
4284-4288 |
Protein |
denotes |
RIP1 |
| T860 |
4284-4288 |
Protein |
denotes |
RIP1 |
| T838 |
4472-4476 |
Protein |
denotes |
RIP1 |
| T861 |
4472-4476 |
Protein |
denotes |
RIP1 |
| T862 |
4532-4541 |
Positive_regulation |
denotes |
activated |
| T13624 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T13566 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T839 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T863 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T864 |
4555-4561 |
Negative_regulation |
denotes |
kinase |
| T13625 |
4562-4571 |
Regulation |
denotes |
dependent |
| T865 |
4562-4571 |
Regulation |
denotes |
dependent |
| T13626 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T866 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T840 |
4709-4711 |
Protein |
denotes |
S6 |
| T867 |
4709-4711 |
Protein |
denotes |
S6 |
| T841 |
4761-4765 |
Protein |
denotes |
TNFα |
| T868 |
4761-4765 |
Protein |
denotes |
TNFα |
| T869 |
4766-4776 |
Gene_expression |
denotes |
production |
| T842 |
4842-4846 |
Protein |
denotes |
RIP1 |
| T870 |
4842-4846 |
Protein |
denotes |
RIP1 |
| T871 |
4955-4959 |
Protein |
denotes |
FADD |
| T843 |
4955-4959 |
Protein |
denotes |
FADD |
| T872 |
4960-4969 |
Negative_regulation |
denotes |
deficient |
| T873 |
5076-5080 |
Protein |
denotes |
TNFα |
| T844 |
5076-5080 |
Protein |
denotes |
TNFα |
| T874 |
5081-5091 |
Gene_expression |
denotes |
production |
| T2894 |
5289-5319 |
Protein |
denotes |
Basic Fibroblast Growth Factor |
| T2923 |
5289-5319 |
Protein |
denotes |
Basic Fibroblast Growth Factor |
| T2924 |
5445-5454 |
Positive_regulation |
denotes |
following |
| T2895 |
5472-5476 |
Protein |
denotes |
TNFα |
| T2925 |
5472-5476 |
Protein |
denotes |
TNFα |
| T2896 |
5516-5525 |
Protein |
denotes |
caspase-8 |
| T2926 |
5516-5525 |
Protein |
denotes |
caspase-8 |
| T2897 |
5987-5996 |
Protein |
denotes |
caspase-8 |
| T2927 |
5987-5996 |
Protein |
denotes |
caspase-8 |
| T2898 |
6001-6005 |
Protein |
denotes |
FADD |
| T2928 |
6001-6005 |
Protein |
denotes |
FADD |
| T2899 |
6411-6420 |
Protein |
denotes |
caspase-8 |
| T2929 |
6411-6420 |
Protein |
denotes |
caspase-8 |
| T2900 |
6461-6465 |
Protein |
denotes |
RIP1 |
| T2930 |
6461-6465 |
Protein |
denotes |
RIP1 |
| T2901 |
6481-6500 |
Protein |
denotes |
RIP1 deubiquitinase |
| T2931 |
6481-6500 |
Protein |
denotes |
RIP1 deubiquitinase |
| T2902 |
6501-6505 |
Protein |
denotes |
CYLD |
| T2932 |
6501-6505 |
Protein |
denotes |
CYLD |
| T2903 |
6726-6730 |
Protein |
denotes |
bFGF |
| T2933 |
6726-6730 |
Protein |
denotes |
bFGF |
| T2904 |
6920-6924 |
Protein |
denotes |
bFGF |
| T2934 |
6920-6924 |
Protein |
denotes |
bFGF |
| T2905 |
6929-6934 |
Protein |
denotes |
IGF-1 |
| T2935 |
6929-6934 |
Protein |
denotes |
IGF-1 |
| T2906 |
6944-6947 |
Protein |
denotes |
EGF |
| T2936 |
6944-6947 |
Protein |
denotes |
EGF |
| T2907 |
7081-7085 |
Protein |
denotes |
bFGF |
| T2937 |
7081-7085 |
Protein |
denotes |
bFGF |
| T2908 |
7142-7146 |
Protein |
denotes |
TNFα |
| T2938 |
7142-7146 |
Protein |
denotes |
TNFα |
| T2909 |
7278-7282 |
Protein |
denotes |
TNFα |
| T2939 |
7278-7282 |
Protein |
denotes |
TNFα |
| T28494 |
7377-7381 |
Protein |
denotes |
bFGF |
| T28490 |
7377-7381 |
Protein |
denotes |
bFGF |
| T28495 |
7386-7391 |
Protein |
denotes |
IGF-1 |
| T28491 |
7386-7391 |
Protein |
denotes |
IGF-1 |
| T28496 |
7471-7475 |
Protein |
denotes |
TNFα |
| T28492 |
7471-7475 |
Protein |
denotes |
TNFα |
| T28497 |
8057-8064 |
Positive_regulation |
denotes |
induced |
| T28498 |
8080-8084 |
Protein |
denotes |
TNFα |
| T28493 |
8080-8084 |
Protein |
denotes |
TNFα |
| T2910 |
8307-8311 |
Protein |
denotes |
RIP1 |
| T2940 |
8307-8311 |
Protein |
denotes |
RIP1 |
| T2911 |
8606-8610 |
Protein |
denotes |
TNFα |
| T2941 |
8606-8610 |
Protein |
denotes |
TNFα |
| T2942 |
8611-8618 |
Positive_regulation |
denotes |
induced |
| T2912 |
8707-8711 |
Protein |
denotes |
RIP1 |
| T2943 |
8707-8711 |
Protein |
denotes |
RIP1 |
| T2913 |
8853-8857 |
Protein |
denotes |
RIP1 |
| T2944 |
8853-8857 |
Protein |
denotes |
RIP1 |
| T2945 |
8992-8996 |
Protein |
denotes |
TNFα |
| T2914 |
8992-8996 |
Protein |
denotes |
TNFα |
| T2946 |
9046-9050 |
Protein |
denotes |
bFGF |
| T2915 |
9046-9050 |
Protein |
denotes |
bFGF |
| T2947 |
9091-9095 |
Protein |
denotes |
RIP1 |
| T2916 |
9091-9095 |
Protein |
denotes |
RIP1 |
| T2948 |
9217-9221 |
Protein |
denotes |
bFGF |
| T2917 |
9217-9221 |
Protein |
denotes |
bFGF |
| T2949 |
9319-9348 |
Protein |
denotes |
bFGF receptor tyrosine kinase |
| T2918 |
9319-9348 |
Protein |
denotes |
bFGF receptor tyrosine kinase |
| T2950 |
9419-9423 |
Protein |
denotes |
bFGF |
| T2919 |
9419-9423 |
Protein |
denotes |
bFGF |
| T2951 |
9544-9557 |
Protein |
denotes |
bFGF receptor |
| T2920 |
9544-9557 |
Protein |
denotes |
bFGF receptor |
| T2952 |
9590-9594 |
Protein |
denotes |
TNFα |
| T2921 |
9590-9594 |
Protein |
denotes |
TNFα |
| T2953 |
9595-9602 |
Positive_regulation |
denotes |
induced |
| T2954 |
9740-9749 |
Positive_regulation |
denotes |
induction |
| T2955 |
9780-9788 |
Positive_regulation |
denotes |
promoted |
| T2956 |
9792-9796 |
Protein |
denotes |
bFGF |
| T2922 |
9792-9796 |
Protein |
denotes |
bFGF |
| T5187 |
10127-10137 |
Positive_regulation |
denotes |
Activation |
| T5188 |
10426-10436 |
Negative_regulation |
denotes |
Inhibition |
| T5189 |
10449-10458 |
Negative_regulation |
denotes |
inhibitor |
| T5190 |
10535-10542 |
Positive_regulation |
denotes |
induced |
| T5191 |
10582-10591 |
Positive_regulation |
denotes |
triggered |
| T5192 |
10595-10599 |
Protein |
denotes |
bFGF |
| T5153 |
10595-10599 |
Protein |
denotes |
bFGF |
| T5193 |
10603-10608 |
Protein |
denotes |
IGF-1 |
| T5154 |
10603-10608 |
Protein |
denotes |
IGF-1 |
| T5194 |
10657-10667 |
Negative_regulation |
denotes |
Inhibition |
| T5195 |
10750-10754 |
Protein |
denotes |
TNFα |
| T5155 |
10750-10754 |
Protein |
denotes |
TNFα |
| T5196 |
10870-10874 |
Protein |
denotes |
TNFα |
| T5156 |
10870-10874 |
Protein |
denotes |
TNFα |
| T5197 |
10875-10882 |
Positive_regulation |
denotes |
induced |
| T5198 |
11088-11092 |
Protein |
denotes |
TNFα |
| T5157 |
11088-11092 |
Protein |
denotes |
TNFα |
| T5199 |
11093-11100 |
Positive_regulation |
denotes |
induced |
| T28934 |
11193-11200 |
Positive_regulation |
denotes |
induced |
| T28935 |
11217-11221 |
Protein |
denotes |
TNFα |
| T28928 |
11217-11221 |
Protein |
denotes |
TNFα |
| T28936 |
11268-11272 |
Protein |
denotes |
TNFα |
| T28929 |
11268-11272 |
Protein |
denotes |
TNFα |
| T28937 |
11374-11383 |
Negative_regulation |
denotes |
inhibitor |
| T28938 |
11516-11520 |
Protein |
denotes |
Akt1 |
| T28930 |
11516-11520 |
Protein |
denotes |
Akt1 |
| T28939 |
11522-11526 |
Protein |
denotes |
Akt2 |
| T28931 |
11522-11526 |
Protein |
denotes |
Akt2 |
| T28940 |
11532-11543 |
Protein |
denotes |
Akt3 siRNAs |
| T28932 |
11532-11543 |
Protein |
denotes |
Akt3 siRNAs |
| T28941 |
11585-11589 |
Protein |
denotes |
TNFα |
| T28933 |
11585-11589 |
Protein |
denotes |
TNFα |
| T28942 |
11624-11634 |
Gene_expression |
denotes |
expression |
| T5200 |
11829-11839 |
Negative_regulation |
denotes |
inhibitors |
| T5201 |
11951-11964 |
Localization |
denotes |
translocation |
| T5202 |
12035-12044 |
Negative_regulation |
denotes |
knockdown |
| T5203 |
12061-12065 |
Protein |
denotes |
Akt1 |
| T5158 |
12061-12065 |
Protein |
denotes |
Akt1 |
| T5204 |
12070-12074 |
Protein |
denotes |
Akt2 |
| T5159 |
12070-12074 |
Protein |
denotes |
Akt2 |
| T5205 |
12121-12128 |
Positive_regulation |
denotes |
induced |
| T5206 |
12150-12154 |
Protein |
denotes |
TNFα |
| T5160 |
12150-12154 |
Protein |
denotes |
TNFα |
| T5207 |
12169-12179 |
Gene_expression |
denotes |
expression |
| T5208 |
12183-12187 |
Protein |
denotes |
Akt3 |
| T5161 |
12183-12187 |
Protein |
denotes |
Akt3 |
| T5209 |
12241-12251 |
Protein |
denotes |
Akt3 siRNA |
| T5162 |
12241-12251 |
Protein |
denotes |
Akt3 siRNA |
| T5210 |
12417-12427 |
Positive_regulation |
denotes |
activation |
| T5211 |
12489-12496 |
Regulation |
denotes |
changes |
| T5212 |
12512-12527 |
Phosphorylation |
denotes |
phosphorylation |
| T5213 |
12555-12559 |
Protein |
denotes |
TNFα |
| T5163 |
12555-12559 |
Protein |
denotes |
TNFα |
| T5214 |
12725-12729 |
Protein |
denotes |
TNFα |
| T5164 |
12725-12729 |
Protein |
denotes |
TNFα |
| T5215 |
12751-12759 |
Positive_regulation |
denotes |
increase |
| T5216 |
12767-12782 |
Phosphorylation |
denotes |
phosphorylation |
| T5217 |
12881-12896 |
Phosphorylation |
denotes |
phosphorylation |
| T5218 |
12925-12935 |
Positive_regulation |
denotes |
activation |
| T5219 |
12977-12985 |
Positive_regulation |
denotes |
increase |
| T5220 |
12993-13008 |
Phosphorylation |
denotes |
phosphorylation |
| T5221 |
13021-13024 |
Protein |
denotes |
p46 |
| T5165 |
13021-13024 |
Protein |
denotes |
p46 |
| T5222 |
13029-13032 |
Protein |
denotes |
p54 |
| T5166 |
13029-13032 |
Protein |
denotes |
p54 |
| T5223 |
13073-13078 |
Protein |
denotes |
c-Jun |
| T5167 |
13073-13078 |
Protein |
denotes |
c-Jun |
| T29394 |
13220-13224 |
Protein |
denotes |
RIP1 |
| T29389 |
13220-13224 |
Protein |
denotes |
RIP1 |
| T29395 |
13242-13257 |
Phosphorylation |
denotes |
phosphorylation |
| T29396 |
13338-13342 |
Protein |
denotes |
TNFα |
| T29390 |
13338-13342 |
Protein |
denotes |
TNFα |
| T29397 |
13460-13464 |
Protein |
denotes |
bFGF |
| T29391 |
13460-13464 |
Protein |
denotes |
bFGF |
| T29398 |
13624-13628 |
Protein |
denotes |
bFGF |
| T29392 |
13624-13628 |
Protein |
denotes |
bFGF |
| T29393 |
13632-13636 |
Protein |
denotes |
bFGF |
| T29399 |
13632-13636 |
Protein |
denotes |
bFGF |
| T5224 |
13745-13749 |
Protein |
denotes |
RIP1 |
| T5168 |
13745-13749 |
Protein |
denotes |
RIP1 |
| T5225 |
13757-13766 |
Negative_regulation |
denotes |
inhibitor |
| T5226 |
13786-13795 |
Negative_regulation |
denotes |
prevented |
| T5227 |
13800-13808 |
Positive_regulation |
denotes |
increase |
| T5228 |
13819-13822 |
Protein |
denotes |
Akt |
| T5169 |
13819-13822 |
Protein |
denotes |
Akt |
| T5229 |
13823-13838 |
Phosphorylation |
denotes |
phosphorylation |
| T5230 |
13988-13995 |
Negative_regulation |
denotes |
reduced |
| T5231 |
14014-14018 |
Protein |
denotes |
TNFα |
| T5170 |
14014-14018 |
Protein |
denotes |
TNFα |
| T5232 |
14089-14094 |
Protein |
denotes |
c-Jun |
| T5171 |
14089-14094 |
Protein |
denotes |
c-Jun |
| T5233 |
14167-14174 |
Positive_regulation |
denotes |
induced |
| T5234 |
14175-14183 |
Positive_regulation |
denotes |
increase |
| T5235 |
14187-14192 |
Protein |
denotes |
c-Jun |
| T5172 |
14187-14192 |
Protein |
denotes |
c-Jun |
| T5236 |
14204-14214 |
Negative_regulation |
denotes |
attenuated |
| T5237 |
14252-14257 |
Regulation |
denotes |
alter |
| T5238 |
14268-14283 |
Phosphorylation |
denotes |
phosphorylation |
| T5239 |
14364-14379 |
Phosphorylation |
denotes |
phosphorylation |
| T5240 |
14402-14406 |
Protein |
denotes |
RIP1 |
| T5173 |
14402-14406 |
Protein |
denotes |
RIP1 |
| T5241 |
14407-14416 |
Regulation |
denotes |
dependent |
| T5242 |
14456-14471 |
Phosphorylation |
denotes |
phosphorylation |
| T5243 |
14515-14524 |
Positive_regulation |
denotes |
following |
| T5244 |
14698-14702 |
Protein |
denotes |
RIP1 |
| T5174 |
14698-14702 |
Protein |
denotes |
RIP1 |
| T5245 |
14725-14735 |
Regulation |
denotes |
regulation |
| T5246 |
14786-14801 |
Phosphorylation |
denotes |
phosphorylation |
| T5247 |
14869-14873 |
Protein |
denotes |
bFGF |
| T5175 |
14869-14873 |
Protein |
denotes |
bFGF |
| T5248 |
14953-14961 |
Positive_regulation |
denotes |
increase |
| T5249 |
14988-15003 |
Phosphorylation |
denotes |
phosphorylation |
| T5250 |
15030-15035 |
Protein |
denotes |
c-Jun |
| T5176 |
15030-15035 |
Protein |
denotes |
c-Jun |
| T5251 |
15158-15162 |
Protein |
denotes |
bFGF |
| T5177 |
15158-15162 |
Protein |
denotes |
bFGF |
| T5252 |
15181-15185 |
Protein |
denotes |
bFGF |
| T5178 |
15181-15185 |
Protein |
denotes |
bFGF |
| T5253 |
15231-15239 |
Positive_regulation |
denotes |
increase |
| T5254 |
15247-15262 |
Phosphorylation |
denotes |
phosphorylation |
| T5255 |
15318-15326 |
Positive_regulation |
denotes |
increase |
| T5256 |
15404-15410 |
Regulation |
denotes |
effect |
| T5257 |
15424-15432 |
Positive_regulation |
denotes |
increase |
| T5258 |
15453-15458 |
Protein |
denotes |
c-Jun |
| T5179 |
15453-15458 |
Protein |
denotes |
c-Jun |
| T5259 |
15459-15474 |
Phosphorylation |
denotes |
phosphorylation |
| T5260 |
15475-15484 |
Positive_regulation |
denotes |
triggered |
| T5261 |
15493-15497 |
Protein |
denotes |
bFGF |
| T5180 |
15493-15497 |
Protein |
denotes |
bFGF |
| T5262 |
15502-15506 |
Protein |
denotes |
bFGF |
| T5181 |
15502-15506 |
Protein |
denotes |
bFGF |
| T5263 |
15597-15601 |
Protein |
denotes |
bFGF |
| T5182 |
15597-15601 |
Protein |
denotes |
bFGF |
| T5264 |
15607-15615 |
Positive_regulation |
denotes |
increase |
| T5265 |
15670-15680 |
Positive_regulation |
denotes |
activation |
| T5266 |
15741-15745 |
Protein |
denotes |
RIP1 |
| T5183 |
15741-15745 |
Protein |
denotes |
RIP1 |
| T5267 |
15863-15871 |
Positive_regulation |
denotes |
increase |
| T5268 |
15882-15897 |
Phosphorylation |
denotes |
phosphorylation |
| T5269 |
15956-15964 |
Positive_regulation |
denotes |
increase |
| T5270 |
15968-15983 |
Phosphorylation |
denotes |
phosphorylation |
| T5271 |
16165-16169 |
Protein |
denotes |
RIP1 |
| T5184 |
16165-16169 |
Protein |
denotes |
RIP1 |
| T5272 |
16170-16179 |
Regulation |
denotes |
dependent |
| T5273 |
16180-16188 |
Positive_regulation |
denotes |
increase |
| T5274 |
16203-16218 |
Phosphorylation |
denotes |
phosphorylation |
| T5275 |
16299-16308 |
Positive_regulation |
denotes |
increases |
| T5276 |
16449-16453 |
Protein |
denotes |
RIP1 |
| T5185 |
16449-16453 |
Protein |
denotes |
RIP1 |
| T7388 |
16463-16467 |
Protein |
denotes |
TNFα |
| T7377 |
16463-16467 |
Protein |
denotes |
TNFα |
| T7389 |
16468-16475 |
Positive_regulation |
denotes |
Induces |
| T7390 |
16495-16510 |
Phosphorylation |
denotes |
Phosphorylation |
| T7391 |
16584-16588 |
Protein |
denotes |
TNFα |
| T7378 |
16584-16588 |
Protein |
denotes |
TNFα |
| T7392 |
16687-16691 |
Protein |
denotes |
TNFα |
| T7379 |
16687-16691 |
Protein |
denotes |
TNFα |
| T7393 |
16692-16699 |
Positive_regulation |
denotes |
induced |
| T7394 |
16700-16707 |
Regulation |
denotes |
changes |
| T7395 |
16722-16737 |
Phosphorylation |
denotes |
phosphorylation |
| T7396 |
16843-16847 |
Protein |
denotes |
TNFα |
| T7380 |
16843-16847 |
Protein |
denotes |
TNFα |
| T7397 |
16871-16881 |
Positive_regulation |
denotes |
activation |
| T7398 |
16976-16980 |
Protein |
denotes |
TNFα |
| T7381 |
16976-16980 |
Protein |
denotes |
TNFα |
| T7399 |
17069-17073 |
Protein |
denotes |
TNFα |
| T7382 |
17069-17073 |
Protein |
denotes |
TNFα |
| T7400 |
17133-17137 |
Protein |
denotes |
TNFα |
| T7383 |
17133-17137 |
Protein |
denotes |
TNFα |
| T7401 |
17175-17183 |
Positive_regulation |
denotes |
increase |
| T7402 |
17191-17206 |
Phosphorylation |
denotes |
phosphorylation |
| T7403 |
17218-17223 |
Protein |
denotes |
c-Jun |
| T7384 |
17218-17223 |
Protein |
denotes |
c-Jun |
| T7404 |
17279-17286 |
Negative_regulation |
denotes |
reduced |
| T7405 |
17377-17381 |
Protein |
denotes |
RIP1 |
| T7385 |
17377-17381 |
Protein |
denotes |
RIP1 |
| T7406 |
17476-17480 |
Protein |
denotes |
Ask1 |
| T7386 |
17476-17480 |
Protein |
denotes |
Ask1 |
| T7407 |
17517-17521 |
Protein |
denotes |
RIP1 |
| T7387 |
17517-17521 |
Protein |
denotes |
RIP1 |
| T8117 |
17568-17576 |
Positive_regulation |
denotes |
Increase |
| T8118 |
17591-17606 |
Phosphorylation |
denotes |
Phosphorylation |
| T8119 |
17698-17702 |
Protein |
denotes |
RIP1 |
| T8112 |
17698-17702 |
Protein |
denotes |
RIP1 |
| T8120 |
17720-17728 |
Positive_regulation |
denotes |
increase |
| T8121 |
17743-17758 |
Phosphorylation |
denotes |
phosphorylation |
| T8122 |
17941-17956 |
Phosphorylation |
denotes |
phosphorylation |
| T8123 |
18051-18066 |
Phosphorylation |
denotes |
phosphorylation |
| T8124 |
18141-18150 |
Negative_regulation |
denotes |
inhibitor |
| T8125 |
18244-18248 |
Protein |
denotes |
TNFα |
| T8113 |
18244-18248 |
Protein |
denotes |
TNFα |
| T8126 |
18252-18256 |
Protein |
denotes |
bFGF |
| T8114 |
18252-18256 |
Protein |
denotes |
bFGF |
| T8127 |
18306-18315 |
Negative_regulation |
denotes |
inhibitor |
| T8128 |
18418-18433 |
Phosphorylation |
denotes |
phosphorylation |
| T8129 |
18462-18466 |
Protein |
denotes |
bFGF |
| T8115 |
18462-18466 |
Protein |
denotes |
bFGF |
| T8130 |
18501-18505 |
Protein |
denotes |
bFGF |
| T8116 |
18501-18505 |
Protein |
denotes |
bFGF |
| T8131 |
18571-18581 |
Positive_regulation |
denotes |
activation |
| T8132 |
18787-18797 |
Positive_regulation |
denotes |
activation |
| T8133 |
18902-18912 |
Positive_regulation |
denotes |
activation |
| T29742 |
19020-19035 |
Phosphorylation |
denotes |
phosphorylation |
| T29743 |
19117-19121 |
Protein |
denotes |
bFGF |
| T29737 |
19117-19121 |
Protein |
denotes |
bFGF |
| T29744 |
19237-19241 |
Protein |
denotes |
TNFα |
| T29738 |
19237-19241 |
Protein |
denotes |
TNFα |
| T29745 |
19249-19253 |
Protein |
denotes |
bFGF |
| T29739 |
19249-19253 |
Protein |
denotes |
bFGF |
| T29746 |
19503-19507 |
Protein |
denotes |
bFGF |
| T29740 |
19503-19507 |
Protein |
denotes |
bFGF |
| T29747 |
19738-19742 |
Protein |
denotes |
bFGF |
| T29741 |
19738-19742 |
Protein |
denotes |
bFGF |
| T9006 |
19961-19969 |
Positive_regulation |
denotes |
increase |
| T9007 |
19980-19995 |
Phosphorylation |
denotes |
phosphorylation |
| T9008 |
20088-20096 |
Positive_regulation |
denotes |
increase |
| T9009 |
20104-20119 |
Phosphorylation |
denotes |
phosphorylation |
| T9010 |
20216-20231 |
Protein |
denotes |
double minute 2 |
| T8964 |
20216-20231 |
Protein |
denotes |
double minute 2 |
| T8965 |
20233-20237 |
Protein |
denotes |
MDM2 |
| T9011 |
20233-20237 |
Protein |
denotes |
MDM2 |
| T8966 |
20273-20304 |
Protein |
denotes |
p70 ribosomal protein S6 Kinase |
| T9012 |
20273-20304 |
Protein |
denotes |
p70 ribosomal protein S6 Kinase |
| T8967 |
20306-20312 |
Protein |
denotes |
p70S6K |
| T9013 |
20306-20312 |
Protein |
denotes |
p70S6K |
| T8968 |
20315-20317 |
Protein |
denotes |
S6 |
| T9014 |
20315-20317 |
Protein |
denotes |
S6 |
| T8969 |
20345-20350 |
Protein |
denotes |
FoxO1 |
| T9015 |
20345-20350 |
Protein |
denotes |
FoxO1 |
| T8970 |
20352-20357 |
Protein |
denotes |
FoxO4 |
| T9016 |
20352-20357 |
Protein |
denotes |
FoxO4 |
| T8971 |
20359-20363 |
Protein |
denotes |
MDM2 |
| T9017 |
20359-20363 |
Protein |
denotes |
MDM2 |
| T8972 |
20414-20420 |
Protein |
denotes |
FoxO3a |
| T9018 |
20414-20420 |
Protein |
denotes |
FoxO3a |
| T8973 |
20422-20428 |
Protein |
denotes |
GSK-3α |
| T9019 |
20422-20428 |
Protein |
denotes |
GSK-3α |
| T8974 |
20429-20430 |
Protein |
denotes |
β |
| T9020 |
20429-20430 |
Protein |
denotes |
β |
| T8975 |
20432-20438 |
Protein |
denotes |
p70S6K |
| T9021 |
20432-20438 |
Protein |
denotes |
p70S6K |
| T8976 |
20457-20459 |
Protein |
denotes |
S6 |
| T9022 |
20457-20459 |
Protein |
denotes |
S6 |
| T9023 |
20563-20571 |
Positive_regulation |
denotes |
increase |
| T9024 |
20579-20594 |
Phosphorylation |
denotes |
phosphorylation |
| T8977 |
20629-20635 |
Protein |
denotes |
pFoxO1 |
| T9025 |
20629-20635 |
Protein |
denotes |
pFoxO1 |
| T9026 |
20929-20938 |
Negative_regulation |
denotes |
abrogated |
| T8978 |
21124-21128 |
Protein |
denotes |
RIP1 |
| T9027 |
21124-21128 |
Protein |
denotes |
RIP1 |
| T30226 |
21290-21294 |
Protein |
denotes |
TNFα |
| T30221 |
21290-21294 |
Protein |
denotes |
TNFα |
| T30227 |
21390-21394 |
Protein |
denotes |
bFGF |
| T30222 |
21390-21394 |
Protein |
denotes |
bFGF |
| T30228 |
21398-21402 |
Protein |
denotes |
bFGF |
| T30223 |
21398-21402 |
Protein |
denotes |
bFGF |
| T30229 |
21528-21535 |
Positive_regulation |
denotes |
induced |
| T30230 |
21551-21555 |
Protein |
denotes |
TNFα |
| T30224 |
21551-21555 |
Protein |
denotes |
TNFα |
| T30231 |
21588-21598 |
Negative_regulation |
denotes |
inhibitors |
| T30232 |
21764-21768 |
Protein |
denotes |
TNFα |
| T30225 |
21764-21768 |
Protein |
denotes |
TNFα |
| T9028 |
22209-22218 |
Negative_regulation |
denotes |
inhibitor |
| T8979 |
22241-22247 |
Protein |
denotes |
Raptor |
| T9029 |
22241-22247 |
Protein |
denotes |
Raptor |
| T9030 |
22332-22341 |
Negative_regulation |
denotes |
inhibitor |
| T9031 |
22377-22386 |
Negative_regulation |
denotes |
inhibitor |
| T9032 |
22416-22425 |
Negative_regulation |
denotes |
inhibited |
| T9033 |
22449-22458 |
Negative_regulation |
denotes |
Knockdown |
| T8980 |
22616-22620 |
Protein |
denotes |
TNFα |
| T9034 |
22616-22620 |
Protein |
denotes |
TNFα |
| T9035 |
22621-22628 |
Positive_regulation |
denotes |
induced |
| T8981 |
22697-22709 |
Protein |
denotes |
p70S6 kinase |
| T9036 |
22697-22709 |
Protein |
denotes |
p70S6 kinase |
| T8982 |
22747-22749 |
Protein |
denotes |
S6 |
| T9037 |
22747-22749 |
Protein |
denotes |
S6 |
| T8983 |
22925-22931 |
Protein |
denotes |
p70S6K |
| T9038 |
22925-22931 |
Protein |
denotes |
p70S6K |
| T8984 |
23011-23013 |
Protein |
denotes |
S6 |
| T9039 |
23011-23013 |
Protein |
denotes |
S6 |
| T9040 |
23014-23029 |
Phosphorylation |
denotes |
phosphorylation |
| T8985 |
23072-23074 |
Protein |
denotes |
S6 |
| T9041 |
23072-23074 |
Protein |
denotes |
S6 |
| T8986 |
23167-23173 |
Protein |
denotes |
p70S6K |
| T9042 |
23167-23173 |
Protein |
denotes |
p70S6K |
| T8987 |
23174-23176 |
Protein |
denotes |
S6 |
| T9043 |
23174-23176 |
Protein |
denotes |
S6 |
| T8988 |
23422-23426 |
Protein |
denotes |
RIP1 |
| T9044 |
23422-23426 |
Protein |
denotes |
RIP1 |
| T9045 |
23467-23479 |
Positive_regulation |
denotes |
upregulation |
| T8989 |
23483-23487 |
Protein |
denotes |
TNFα |
| T9046 |
23483-23487 |
Protein |
denotes |
TNFα |
| T9047 |
23635-23644 |
Positive_regulation |
denotes |
increased |
| T9048 |
23645-23654 |
Gene_expression |
denotes |
synthesis |
| T8990 |
23658-23662 |
Protein |
denotes |
TNFα |
| T9049 |
23658-23662 |
Protein |
denotes |
TNFα |
| T9050 |
23747-23757 |
Positive_regulation |
denotes |
contribute |
| T8991 |
23761-23765 |
Protein |
denotes |
TNFα |
| T9051 |
23761-23765 |
Protein |
denotes |
TNFα |
| T9052 |
23766-23775 |
Gene_expression |
denotes |
synthesis |
| T8992 |
23795-23799 |
Protein |
denotes |
RIP1 |
| T9053 |
23795-23799 |
Protein |
denotes |
RIP1 |
| T9054 |
23800-23809 |
Regulation |
denotes |
dependent |
| T9055 |
23810-23818 |
Positive_regulation |
denotes |
increase |
| T8993 |
23822-23826 |
Protein |
denotes |
TNFα |
| T9056 |
23822-23826 |
Protein |
denotes |
TNFα |
| T8994 |
23864-23868 |
Protein |
denotes |
TNFα |
| T9057 |
23864-23868 |
Protein |
denotes |
TNFα |
| T8995 |
23929-23933 |
Protein |
denotes |
RIP1 |
| T9058 |
23929-23933 |
Protein |
denotes |
RIP1 |
| T8996 |
23974-23978 |
Protein |
denotes |
bFGF |
| T9059 |
23974-23978 |
Protein |
denotes |
bFGF |
| T9060 |
23985-23994 |
Positive_regulation |
denotes |
triggered |
| T9061 |
24000-24009 |
Positive_regulation |
denotes |
induction |
| T8997 |
24013-24017 |
Protein |
denotes |
TNFα |
| T9062 |
24013-24017 |
Protein |
denotes |
TNFα |
| T9063 |
24113-24121 |
Positive_regulation |
denotes |
increase |
| T9064 |
24150-24156 |
Positive_regulation |
denotes |
caused |
| T9065 |
24166-24178 |
Positive_regulation |
denotes |
upregulation |
| T8998 |
24182-24186 |
Protein |
denotes |
TNFα |
| T9066 |
24182-24186 |
Protein |
denotes |
TNFα |
| T9067 |
24215-24224 |
Positive_regulation |
denotes |
increased |
| T8999 |
24371-24375 |
Protein |
denotes |
TNFα |
| T9068 |
24371-24375 |
Protein |
denotes |
TNFα |
| T9069 |
24376-24385 |
Gene_expression |
denotes |
synthesis |
| T30660 |
24464-24468 |
Protein |
denotes |
TNFα |
| T30652 |
24464-24468 |
Protein |
denotes |
TNFα |
| T30661 |
24574-24578 |
Protein |
denotes |
bFGF |
| T30653 |
24574-24578 |
Protein |
denotes |
bFGF |
| T30662 |
24654-24659 |
Protein |
denotes |
mTNFα |
| T30654 |
24654-24659 |
Protein |
denotes |
mTNFα |
| T30663 |
24690-24693 |
Protein |
denotes |
18S |
| T30655 |
24690-24693 |
Protein |
denotes |
18S |
| T30664 |
24742-24746 |
Protein |
denotes |
TNFα |
| T30656 |
24742-24746 |
Protein |
denotes |
TNFα |
| T30665 |
24848-24852 |
Protein |
denotes |
TNFα |
| T30657 |
24848-24852 |
Protein |
denotes |
TNFα |
| T30666 |
24894-24903 |
Negative_regulation |
denotes |
knockdown |
| T30667 |
24973-24977 |
Protein |
denotes |
TNFα |
| T30658 |
24973-24977 |
Protein |
denotes |
TNFα |
| T30668 |
25020-25025 |
Protein |
denotes |
mTNFα |
| T30659 |
25020-25025 |
Protein |
denotes |
mTNFα |
| T9070 |
25146-25156 |
Positive_regulation |
denotes |
contribute |
| T9071 |
25164-25176 |
Positive_regulation |
denotes |
upregulation |
| T9000 |
25180-25184 |
Protein |
denotes |
TNFα |
| T9072 |
25180-25184 |
Protein |
denotes |
TNFα |
| T9073 |
25253-25262 |
Negative_regulation |
denotes |
knockdown |
| T9074 |
25279-25286 |
Negative_regulation |
denotes |
reduced |
| T9001 |
25287-25291 |
Protein |
denotes |
TNFα |
| T9075 |
25287-25291 |
Protein |
denotes |
TNFα |
| T9002 |
25349-25353 |
Protein |
denotes |
RIP1 |
| T9076 |
25349-25353 |
Protein |
denotes |
RIP1 |
| T9077 |
25362-25372 |
Negative_regulation |
denotes |
inhibitors |
| T9078 |
25380-25386 |
Regulation |
denotes |
effect |
| T9003 |
25404-25408 |
Protein |
denotes |
TNFα |
| T9079 |
25404-25408 |
Protein |
denotes |
TNFα |
| T9004 |
25463-25467 |
Protein |
denotes |
bFGF |
| T9080 |
25463-25467 |
Protein |
denotes |
bFGF |
| T9081 |
25570-25578 |
Positive_regulation |
denotes |
increase |
| T9005 |
25582-25586 |
Protein |
denotes |
TNFα |
| T9082 |
25582-25586 |
Protein |
denotes |
TNFα |
| T9083 |
25587-25596 |
Gene_expression |
denotes |
synthesis |
| T11824 |
25702-25706 |
Protein |
denotes |
TNFα |
| T11812 |
25702-25706 |
Protein |
denotes |
TNFα |
| T11825 |
25707-25716 |
Gene_expression |
denotes |
synthesis |
| T11826 |
25806-25816 |
Negative_regulation |
denotes |
inhibitors |
| T11827 |
25820-25825 |
Negative_regulation |
denotes |
block |
| T11828 |
25830-25838 |
Positive_regulation |
denotes |
increase |
| T11829 |
25842-25846 |
Protein |
denotes |
TNFα |
| T11813 |
25842-25846 |
Protein |
denotes |
TNFα |
| T11830 |
25927-25936 |
Negative_regulation |
denotes |
Knockdown |
| T11831 |
25953-25957 |
Protein |
denotes |
Akt1 |
| T11814 |
25953-25957 |
Protein |
denotes |
Akt1 |
| T11832 |
25962-25966 |
Protein |
denotes |
Akt2 |
| T11815 |
25962-25966 |
Protein |
denotes |
Akt2 |
| T11833 |
25970-25980 |
Negative_regulation |
denotes |
inhibition |
| T11834 |
26037-26045 |
Positive_regulation |
denotes |
increase |
| T11835 |
26057-26062 |
Protein |
denotes |
c-Jun |
| T11816 |
26057-26062 |
Protein |
denotes |
c-Jun |
| T11836 |
26063-26078 |
Phosphorylation |
denotes |
phosphorylation |
| T11837 |
26143-26147 |
Protein |
denotes |
RIP1 |
| T11817 |
26143-26147 |
Protein |
denotes |
RIP1 |
| T11838 |
26181-26191 |
Negative_regulation |
denotes |
inhibition |
| T11839 |
26204-26213 |
Negative_regulation |
denotes |
inhibited |
| T11840 |
26258-26262 |
Protein |
denotes |
bFGF |
| T11818 |
26258-26262 |
Protein |
denotes |
bFGF |
| T11841 |
26272-26279 |
Positive_regulation |
denotes |
induced |
| T11842 |
26288-26293 |
Protein |
denotes |
c-Jun |
| T11819 |
26288-26293 |
Protein |
denotes |
c-Jun |
| T11843 |
26294-26309 |
Phosphorylation |
denotes |
phosphorylation |
| T11844 |
26322-26331 |
Negative_regulation |
denotes |
Knockdown |
| T11845 |
26359-26365 |
Protein |
denotes |
p70S6K |
| T11820 |
26359-26365 |
Protein |
denotes |
p70S6K |
| T11846 |
26392-26402 |
Negative_regulation |
denotes |
attenuated |
| T11847 |
26430-26438 |
Positive_regulation |
denotes |
increase |
| T11848 |
26450-26455 |
Protein |
denotes |
c-Jun |
| T11821 |
26450-26455 |
Protein |
denotes |
c-Jun |
| T11849 |
26456-26471 |
Phosphorylation |
denotes |
phosphorylation |
| T11850 |
26550-26553 |
Protein |
denotes |
S6K |
| T11822 |
26550-26553 |
Protein |
denotes |
S6K |
| T11851 |
26583-26587 |
Protein |
denotes |
RIP1 |
| T11823 |
26583-26587 |
Protein |
denotes |
RIP1 |
| T12724 |
26691-26695 |
Protein |
denotes |
PDK1 |
| T12717 |
26691-26695 |
Protein |
denotes |
PDK1 |
| T12725 |
26708-26716 |
Positive_regulation |
denotes |
Increase |
| T12726 |
26731-26746 |
Phosphorylation |
denotes |
Phosphorylation |
| T12727 |
26784-26794 |
Regulation |
denotes |
regulation |
| T12728 |
26833-26844 |
Binding |
denotes |
recruitment |
| T12729 |
26878-26886 |
Positive_regulation |
denotes |
mediated |
| T12730 |
26894-26901 |
Binding |
denotes |
binding |
| T12731 |
26909-26928 |
Entity |
denotes |
pleckstrin homology |
| T12732 |
26930-26940 |
Entity |
denotes |
PH) domain |
| T12733 |
27044-27058 |
Phosphorylation |
denotes |
phosphorylated |
| T12734 |
27083-27128 |
Protein |
denotes |
3-phosphoinositide dependent protein kinase-1 |
| T12718 |
27083-27128 |
Protein |
denotes |
3-phosphoinositide dependent protein kinase-1 |
| T12735 |
27130-27134 |
Protein |
denotes |
PDK1 |
| T12719 |
27130-27134 |
Protein |
denotes |
PDK1 |
| T12736 |
27225-27240 |
Phosphorylation |
denotes |
phosphorylation |
| T12737 |
27244-27253 |
Positive_regulation |
denotes |
increased |
| T12738 |
27311-27320 |
Regulation |
denotes |
dependent |
| T12739 |
27333-27337 |
Protein |
denotes |
PDK1 |
| T12720 |
27333-27337 |
Protein |
denotes |
PDK1 |
| T12740 |
27362-27366 |
Protein |
denotes |
PDK1 |
| T12721 |
27362-27366 |
Protein |
denotes |
PDK1 |
| T12741 |
27487-27502 |
Phosphorylation |
denotes |
phosphorylation |
| T12742 |
27546-27550 |
Protein |
denotes |
PDK1 |
| T12722 |
27546-27550 |
Protein |
denotes |
PDK1 |
| T12743 |
27582-27591 |
Negative_regulation |
denotes |
inhibited |
| T12744 |
27603-27618 |
Phosphorylation |
denotes |
phosphorylation |
| T12745 |
27652-27656 |
Protein |
denotes |
PDK1 |
| T12723 |
27652-27656 |
Protein |
denotes |
PDK1 |
| T12746 |
27706-27716 |
Positive_regulation |
denotes |
activation |
| T13595 |
27738-27748 |
Gene_expression |
denotes |
Expression |
| T13596 |
27767-27773 |
Positive_regulation |
denotes |
Active |
| T13597 |
27853-27863 |
Gene_expression |
denotes |
expressing |
| T13598 |
27896-27900 |
Protein |
denotes |
Akt1 |
| T13552 |
27896-27900 |
Protein |
denotes |
Akt1 |
| T13599 |
27902-27909 |
Protein |
denotes |
Myr-Akt |
| T13553 |
27902-27909 |
Protein |
denotes |
Myr-Akt |
| T13600 |
27948-27953 |
Protein |
denotes |
K179M |
| T13554 |
27948-27953 |
Protein |
denotes |
K179M |
| T13601 |
28024-28028 |
Protein |
denotes |
RIP1 |
| T13555 |
28024-28028 |
Protein |
denotes |
RIP1 |
| T13602 |
28043-28053 |
Positive_regulation |
denotes |
activation |
| T13603 |
28096-28100 |
Protein |
denotes |
Akt1 |
| T13556 |
28096-28100 |
Protein |
denotes |
Akt1 |
| T13604 |
28102-28109 |
Protein |
denotes |
Myr-Akt |
| T13557 |
28102-28109 |
Protein |
denotes |
Myr-Akt |
| T13605 |
28324-28333 |
Positive_regulation |
denotes |
resulting |
| T13606 |
28416-28426 |
Gene_expression |
denotes |
expressing |
| T13607 |
28427-28434 |
Protein |
denotes |
Myr-Akt |
| T13558 |
28427-28434 |
Protein |
denotes |
Myr-Akt |
| T13608 |
28713-28720 |
Protein |
denotes |
Myr-Akt |
| T13559 |
28713-28720 |
Protein |
denotes |
Myr-Akt |
| T13609 |
28734-28739 |
Protein |
denotes |
K179M |
| T13560 |
28734-28739 |
Protein |
denotes |
K179M |
| T13610 |
28826-28833 |
Protein |
denotes |
Myr-Akt |
| T13561 |
28826-28833 |
Protein |
denotes |
Myr-Akt |
| T13611 |
28892-28900 |
Positive_regulation |
denotes |
increase |
| T13612 |
28915-28930 |
Phosphorylation |
denotes |
phosphorylation |
| T13613 |
29030-29035 |
Protein |
denotes |
c-Jun |
| T13562 |
29030-29035 |
Protein |
denotes |
c-Jun |
| T13614 |
29036-29051 |
Phosphorylation |
denotes |
phosphorylation |
| T13615 |
29066-29078 |
Positive_regulation |
denotes |
upregulation |
| T13616 |
29082-29086 |
Protein |
denotes |
TNFα |
| T13563 |
29082-29086 |
Protein |
denotes |
TNFα |
| T13617 |
29164-29168 |
Regulation |
denotes |
role |
| T13618 |
29324-29334 |
Positive_regulation |
denotes |
activation |
| T13619 |
29384-29388 |
Protein |
denotes |
RIP1 |
| T13564 |
29384-29388 |
Protein |
denotes |
RIP1 |
| T13620 |
29414-29422 |
Regulation |
denotes |
regulate |
| T13621 |
29427-29437 |
Positive_regulation |
denotes |
activation |
| T13622 |
29493-29497 |
Protein |
denotes |
RIP1 |
| T13565 |
29493-29497 |
Protein |
denotes |
RIP1 |
| T13623 |
29536-29544 |
Positive_regulation |
denotes |
required |
| T31172 |
29874-29881 |
Positive_regulation |
denotes |
induced |
| T31173 |
30397-30401 |
Protein |
denotes |
TNFα |
| T31169 |
30397-30401 |
Protein |
denotes |
TNFα |
| T31174 |
30468-30471 |
Protein |
denotes |
18S |
| T31170 |
30468-30471 |
Protein |
denotes |
18S |
| T31175 |
30494-30504 |
Gene_expression |
denotes |
expressing |
| T31176 |
30699-30703 |
Protein |
denotes |
TNFα |
| T31171 |
30699-30703 |
Protein |
denotes |
TNFα |
| T13627 |
30828-30835 |
Protein |
denotes |
Myr-Akt |
| T13567 |
30828-30835 |
Protein |
denotes |
Myr-Akt |
| T13628 |
30855-30864 |
Positive_regulation |
denotes |
increased |
| T13629 |
30865-30872 |
Protein |
denotes |
Myr-Akt |
| T13568 |
30865-30872 |
Protein |
denotes |
Myr-Akt |
| T13630 |
30986-30995 |
Positive_regulation |
denotes |
increased |
| T13631 |
31005-31015 |
Gene_expression |
denotes |
expression |
| T13632 |
31019-31026 |
Protein |
denotes |
Myr-Akt |
| T13569 |
31019-31026 |
Protein |
denotes |
Myr-Akt |
| T13633 |
31040-31045 |
Protein |
denotes |
K179M |
| T13570 |
31040-31045 |
Protein |
denotes |
K179M |
| T13634 |
31204-31213 |
Positive_regulation |
denotes |
increased |
| T13635 |
31232-31239 |
Protein |
denotes |
Myr-Akt |
| T13571 |
31232-31239 |
Protein |
denotes |
Myr-Akt |
| T13636 |
31268-31274 |
Protein |
denotes |
p70S6K |
| T13572 |
31268-31274 |
Protein |
denotes |
p70S6K |
| T13637 |
31276-31278 |
Protein |
denotes |
S6 |
| T13573 |
31276-31278 |
Protein |
denotes |
S6 |
| T13638 |
31290-31295 |
Protein |
denotes |
FoxO4 |
| T13574 |
31290-31295 |
Protein |
denotes |
FoxO4 |
| T13639 |
31308-31322 |
Phosphorylation |
denotes |
phosphorylated |
| T13640 |
31335-31342 |
Negative_regulation |
denotes |
absence |
| T13641 |
31375-31390 |
Phosphorylation |
denotes |
phosphorylation |
| T13642 |
31394-31399 |
Protein |
denotes |
FoxO1 |
| T13575 |
31394-31399 |
Protein |
denotes |
FoxO1 |
| T13643 |
31404-31408 |
Protein |
denotes |
MDM2 |
| T13576 |
31404-31408 |
Protein |
denotes |
MDM2 |
| T13644 |
31427-31436 |
Positive_regulation |
denotes |
increased |
| T13645 |
31501-31516 |
Phosphorylation |
denotes |
phosphorylation |
| T13646 |
31520-31527 |
Protein |
denotes |
Myr-Akt |
| T13577 |
31520-31527 |
Protein |
denotes |
Myr-Akt |
| T13647 |
31653-31657 |
Protein |
denotes |
TNFα |
| T13578 |
31653-31657 |
Protein |
denotes |
TNFα |
| T13648 |
31658-31668 |
Gene_expression |
denotes |
production |
| T13649 |
31675-31684 |
Regulation |
denotes |
dependent |
| T13650 |
31697-31706 |
Gene_expression |
denotes |
expressed |
| T13651 |
31707-31714 |
Protein |
denotes |
Myr-Akt |
| T13579 |
31707-31714 |
Protein |
denotes |
Myr-Akt |
| T13652 |
31824-31836 |
Localization |
denotes |
localization |
| T13653 |
31847-31855 |
Positive_regulation |
denotes |
required |
| T13654 |
31885-31892 |
Negative_regulation |
denotes |
lacking |
| T13655 |
31976-31985 |
Positive_regulation |
denotes |
increased |
| T13656 |
31993-32008 |
Phosphorylation |
denotes |
phosphorylation |
| T13657 |
32120-32124 |
Regulation |
denotes |
role |
| T13658 |
32136-32151 |
Phosphorylation |
denotes |
phosphorylation |
| T13659 |
32159-32169 |
Regulation |
denotes |
regulation |
| T13660 |
32276-32285 |
Negative_regulation |
denotes |
reduction |
| T13661 |
32315-32318 |
Protein |
denotes |
Akt |
| T13580 |
32315-32318 |
Protein |
denotes |
Akt |
| T13662 |
32771-32783 |
Protein |
denotes |
S473D mutant |
| T13581 |
32771-32783 |
Protein |
denotes |
S473D mutant |
| T13663 |
32795-32809 |
Phosphorylation |
denotes |
phosphorylated |
| T13664 |
32872-32879 |
Negative_regulation |
denotes |
reduced |
| T13665 |
32896-32901 |
Protein |
denotes |
S473A |
| T13582 |
32896-32901 |
Protein |
denotes |
S473A |
| T13666 |
32963-32968 |
Protein |
denotes |
S473A |
| T13583 |
32963-32968 |
Protein |
denotes |
S473A |
| T13667 |
32998-33012 |
Phosphorylation |
denotes |
phosphorylated |
| T13668 |
33076-33080 |
Entity |
denotes |
site |
| T13669 |
33087-33101 |
Phosphorylation |
denotes |
phosphorylated |
| T13670 |
33133-33137 |
Protein |
denotes |
PDK1 |
| T13584 |
33133-33137 |
Protein |
denotes |
PDK1 |
| T13671 |
33141-33154 |
Phosphorylation |
denotes |
phosphorylate |
| T13672 |
33271-33286 |
Phosphorylation |
denotes |
phosphorylation |
| T13673 |
33298-33303 |
Protein |
denotes |
c-Jun |
| T13585 |
33298-33303 |
Protein |
denotes |
c-Jun |
| T13674 |
33309-33313 |
Protein |
denotes |
TNFα |
| T13586 |
33309-33313 |
Protein |
denotes |
TNFα |
| T13675 |
33339-33344 |
Protein |
denotes |
T308D |
| T13587 |
33339-33344 |
Protein |
denotes |
T308D |
| T13676 |
33367-33373 |
Positive_regulation |
denotes |
active |
| T13677 |
33583-33588 |
Protein |
denotes |
T308D |
| T13588 |
33583-33588 |
Protein |
denotes |
T308D |
| T13678 |
33668-33682 |
Phosphorylation |
denotes |
phosphorylated |
| T13679 |
33690-33697 |
Protein |
denotes |
Myr-Akt |
| T13589 |
33690-33697 |
Protein |
denotes |
Myr-Akt |
| T13680 |
33742-33747 |
Protein |
denotes |
FoxO1 |
| T13590 |
33742-33747 |
Protein |
denotes |
FoxO1 |
| T13681 |
33749-33754 |
Protein |
denotes |
Foxo4 |
| T13591 |
33749-33754 |
Protein |
denotes |
Foxo4 |
| T13682 |
33756-33760 |
Protein |
denotes |
MDM2 |
| T13592 |
33756-33760 |
Protein |
denotes |
MDM2 |
| T13683 |
33766-33772 |
Protein |
denotes |
p70S6K |
| T13593 |
33766-33772 |
Protein |
denotes |
p70S6K |
| T13684 |
33943-33951 |
Positive_regulation |
denotes |
allowing |
| T13685 |
33959-33972 |
Phosphorylation |
denotes |
phosphorylate |
| T13686 |
34004-34011 |
Positive_regulation |
denotes |
promote |
| T13687 |
34012-34016 |
Protein |
denotes |
TNFα |
| T13594 |
34012-34016 |
Protein |
denotes |
TNFα |
| T13688 |
34017-34026 |
Gene_expression |
denotes |
synthesis |
| T16782 |
34073-34081 |
Regulation |
denotes |
Controls |
| T16783 |
34082-34086 |
Protein |
denotes |
TNFα |
| T16763 |
34082-34086 |
Protein |
denotes |
TNFα |
| T16784 |
34087-34097 |
Gene_expression |
denotes |
Production |
| T16785 |
34149-34153 |
Protein |
denotes |
RIP1 |
| T16764 |
34149-34153 |
Protein |
denotes |
RIP1 |
| T16786 |
34303-34343 |
Protein |
denotes |
Fas-associated protein with death domain |
| T16765 |
34303-34343 |
Protein |
denotes |
Fas-associated protein with death domain |
| T16787 |
34345-34349 |
Protein |
denotes |
FADD |
| T16766 |
34345-34349 |
Protein |
denotes |
FADD |
| T16788 |
34481-34488 |
Positive_regulation |
denotes |
induced |
| T16789 |
34509-34513 |
Protein |
denotes |
TNFα |
| T16767 |
34509-34513 |
Protein |
denotes |
TNFα |
| T16790 |
34571-34575 |
Protein |
denotes |
RIP1 |
| T16768 |
34571-34575 |
Protein |
denotes |
RIP1 |
| T16791 |
34583-34592 |
Regulation |
denotes |
dependent |
| T16792 |
34593-34601 |
Positive_regulation |
denotes |
increase |
| T16793 |
34609-34624 |
Phosphorylation |
denotes |
phosphorylation |
| T16794 |
34718-34722 |
Protein |
denotes |
TNFα |
| T16769 |
34718-34722 |
Protein |
denotes |
TNFα |
| T16795 |
34813-34822 |
Negative_regulation |
denotes |
inhibited |
| T16796 |
34831-34835 |
Protein |
denotes |
RIP1 |
| T16770 |
34831-34835 |
Protein |
denotes |
RIP1 |
| T16797 |
34844-34854 |
Negative_regulation |
denotes |
inhibitors |
| T16798 |
34879-34889 |
Negative_regulation |
denotes |
inhibition |
| T16799 |
34980-34990 |
Regulation |
denotes |
regulation |
| T16800 |
35004-35008 |
Protein |
denotes |
TNFα |
| T16771 |
35004-35008 |
Protein |
denotes |
TNFα |
| T16801 |
35117-35127 |
Positive_regulation |
denotes |
activation |
| T16802 |
35131-35135 |
Protein |
denotes |
RIP1 |
| T16772 |
35131-35135 |
Protein |
denotes |
RIP1 |
| T31826 |
35293-35297 |
Protein |
denotes |
TNFα |
| T31814 |
35293-35297 |
Protein |
denotes |
TNFα |
| T31827 |
35298-35308 |
Gene_expression |
denotes |
production |
| T31828 |
35333-35337 |
Protein |
denotes |
FADD |
| T31815 |
35333-35337 |
Protein |
denotes |
FADD |
| T31829 |
35338-35347 |
Negative_regulation |
denotes |
deficient |
| T31830 |
35379-35383 |
Protein |
denotes |
TNFα |
| T31816 |
35379-35383 |
Protein |
denotes |
TNFα |
| T31831 |
35421-35425 |
Protein |
denotes |
TNFα |
| T31817 |
35421-35425 |
Protein |
denotes |
TNFα |
| T31832 |
35476-35479 |
Protein |
denotes |
18S |
| T31818 |
35476-35479 |
Protein |
denotes |
18S |
| T31833 |
35631-35635 |
Protein |
denotes |
TNFα |
| T31819 |
35631-35635 |
Protein |
denotes |
TNFα |
| T31834 |
35726-35736 |
Gene_expression |
denotes |
expressing |
| T31835 |
35785-35789 |
Protein |
denotes |
TNFα |
| T31820 |
35785-35789 |
Protein |
denotes |
TNFα |
| T31836 |
35790-35798 |
Positive_regulation |
denotes |
followed |
| T31837 |
35817-35821 |
Protein |
denotes |
TNFα |
| T31821 |
35817-35821 |
Protein |
denotes |
TNFα |
| T31838 |
35881-35891 |
Gene_expression |
denotes |
expressing |
| T31839 |
35908-35912 |
Protein |
denotes |
Akt1 |
| T31822 |
35908-35912 |
Protein |
denotes |
Akt1 |
| T31840 |
35916-35920 |
Protein |
denotes |
Akt2 |
| T31823 |
35916-35920 |
Protein |
denotes |
Akt2 |
| T31841 |
35952-35956 |
Protein |
denotes |
TNFα |
| T31824 |
35952-35956 |
Protein |
denotes |
TNFα |
| T31842 |
35957-35965 |
Positive_regulation |
denotes |
followed |
| T31843 |
35984-35988 |
Protein |
denotes |
TNFα |
| T31825 |
35984-35988 |
Protein |
denotes |
TNFα |
| T16803 |
36147-36155 |
Negative_regulation |
denotes |
deletion |
| T16804 |
36216-36223 |
Positive_regulation |
denotes |
induced |
| T16805 |
36243-36247 |
Protein |
denotes |
TNFα |
| T16773 |
36243-36247 |
Protein |
denotes |
TNFα |
| T16806 |
36290-36296 |
Positive_regulation |
denotes |
active |
| T16807 |
36335-36339 |
Protein |
denotes |
TNFα |
| T16774 |
36335-36339 |
Protein |
denotes |
TNFα |
| T16808 |
36340-36355 |
Transcription |
denotes |
mRNA production |
| T16809 |
36356-36370 |
Positive_regulation |
denotes |
in response to |
| T16810 |
36371-36375 |
Protein |
denotes |
TNFα |
| T16775 |
36371-36375 |
Protein |
denotes |
TNFα |
| T16811 |
36478-36487 |
Negative_regulation |
denotes |
knockdown |
| T16812 |
36511-36521 |
Gene_expression |
denotes |
expressing |
| T16813 |
36533-36537 |
Protein |
denotes |
Akt1 |
| T16776 |
36533-36537 |
Protein |
denotes |
Akt1 |
| T16814 |
36541-36545 |
Protein |
denotes |
Akt2 |
| T16777 |
36541-36545 |
Protein |
denotes |
Akt2 |
| T16815 |
36551-36565 |
Phosphorylation |
denotes |
phosphorylated |
| T16816 |
36591-36595 |
Protein |
denotes |
TNFα |
| T16778 |
36591-36595 |
Protein |
denotes |
TNFα |
| T16817 |
36645-36649 |
Protein |
denotes |
RIP1 |
| T16779 |
36645-36649 |
Protein |
denotes |
RIP1 |
| T16818 |
36650-36659 |
Regulation |
denotes |
dependent |
| T16819 |
36660-36664 |
Protein |
denotes |
TNFα |
| T16780 |
36660-36664 |
Protein |
denotes |
TNFα |
| T16820 |
36670-36682 |
Positive_regulation |
denotes |
upregulation |
| T16821 |
36804-36813 |
Regulation |
denotes |
autocrine |
| T16822 |
36814-36818 |
Protein |
denotes |
TNFα |
| T16781 |
36814-36818 |
Protein |
denotes |
TNFα |
| T16823 |
36819-36828 |
Gene_expression |
denotes |
synthesis |
| T18246 |
37024-37028 |
Protein |
denotes |
RIP1 |
| T18220 |
37024-37028 |
Protein |
denotes |
RIP1 |
| T18247 |
37118-37122 |
Protein |
denotes |
RIP1 |
| T18221 |
37118-37122 |
Protein |
denotes |
RIP1 |
| T18248 |
37374-37378 |
Protein |
denotes |
RIP1 |
| T18222 |
37374-37378 |
Protein |
denotes |
RIP1 |
| T18249 |
37414-37422 |
Positive_regulation |
denotes |
increase |
| T18250 |
37430-37445 |
Phosphorylation |
denotes |
phosphorylation |
| T18251 |
37529-37544 |
Phosphorylation |
denotes |
phosphorylation |
| T18252 |
37665-37677 |
Localization |
denotes |
localization |
| T18253 |
37686-37696 |
Gene_expression |
denotes |
Expression |
| T18254 |
37750-37757 |
Protein |
denotes |
Myr-Akt |
| T18223 |
37750-37757 |
Protein |
denotes |
Myr-Akt |
| T18255 |
37823-37833 |
Gene_expression |
denotes |
expression |
| T18256 |
37837-37844 |
Protein |
denotes |
Myr-Akt |
| T18224 |
37837-37844 |
Protein |
denotes |
Myr-Akt |
| T18257 |
37913-37917 |
Protein |
denotes |
RIP1 |
| T18225 |
37913-37917 |
Protein |
denotes |
RIP1 |
| T18258 |
37944-37952 |
Positive_regulation |
denotes |
required |
| T18259 |
37964-37979 |
Phosphorylation |
denotes |
phosphorylation |
| T32293 |
38138-38142 |
Protein |
denotes |
RIP1 |
| T32290 |
38138-38142 |
Protein |
denotes |
RIP1 |
| T32294 |
38207-38222 |
Phosphorylation |
denotes |
phosphorylation |
| T32295 |
38297-38301 |
Protein |
denotes |
RIP1 |
| T32291 |
38297-38301 |
Protein |
denotes |
RIP1 |
| T32296 |
38355-38359 |
Protein |
denotes |
TNFα |
| T32292 |
38355-38359 |
Protein |
denotes |
TNFα |
| T32297 |
38360-38369 |
Gene_expression |
denotes |
synthesis |
| T32298 |
38371-38381 |
Positive_regulation |
denotes |
Activation |
| T32299 |
38413-38418 |
Positive_regulation |
denotes |
leads |
| T32300 |
38423-38438 |
Phosphorylation |
denotes |
phosphorylation |
| T18260 |
38566-38576 |
Negative_regulation |
denotes |
inhibitors |
| T18261 |
38578-38587 |
Negative_regulation |
denotes |
knockdown |
| T18262 |
38613-38623 |
Gene_expression |
denotes |
expression |
| T18263 |
38667-38677 |
Positive_regulation |
denotes |
activation |
| T18264 |
38882-38897 |
Phosphorylation |
denotes |
phosphorylation |
| T18265 |
39170-39174 |
Protein |
denotes |
RIP1 |
| T18226 |
39170-39174 |
Protein |
denotes |
RIP1 |
| T18266 |
39287-39296 |
Regulation |
denotes |
autocrine |
| T18267 |
39297-39301 |
Protein |
denotes |
TNFα |
| T18227 |
39297-39301 |
Protein |
denotes |
TNFα |
| T18268 |
39302-39311 |
Gene_expression |
denotes |
synthesis |
| T18269 |
39417-39432 |
Phosphorylation |
denotes |
phosphorylation |
| T18270 |
39569-39578 |
Negative_regulation |
denotes |
inhibited |
| T18271 |
39579-39583 |
Protein |
denotes |
TNFα |
| T18228 |
39579-39583 |
Protein |
denotes |
TNFα |
| T18272 |
39584-39594 |
Gene_expression |
denotes |
production |
| T18273 |
39617-39626 |
Negative_regulation |
denotes |
inhibited |
| T18274 |
39657-39672 |
Phosphorylation |
denotes |
phosphorylation |
| T18275 |
39820-39833 |
Protein |
denotes |
p110δ subunit |
| T18229 |
39820-39833 |
Protein |
denotes |
p110δ subunit |
| T18276 |
39851-39855 |
Protein |
denotes |
PDK1 |
| T18230 |
39851-39855 |
Protein |
denotes |
PDK1 |
| T18277 |
39901-39908 |
Negative_regulation |
denotes |
inhibit |
| T18278 |
39919-39934 |
Phosphorylation |
denotes |
phosphorylation |
| T18279 |
40119-40123 |
Protein |
denotes |
JNK1 |
| T18231 |
40119-40123 |
Protein |
denotes |
JNK1 |
| T18280 |
40128-40132 |
Protein |
denotes |
JNK2 |
| T18232 |
40128-40132 |
Protein |
denotes |
JNK2 |
| T18281 |
40184-40193 |
Negative_regulation |
denotes |
knockdown |
| T18282 |
40197-40201 |
Protein |
denotes |
JNK1 |
| T18233 |
40197-40201 |
Protein |
denotes |
JNK1 |
| T18283 |
40202-40203 |
Protein |
denotes |
2 |
| T18234 |
40202-40203 |
Protein |
denotes |
2 |
| T18284 |
40212-40227 |
Phosphorylation |
denotes |
phosphorylation |
| T18285 |
40251-40261 |
Negative_regulation |
denotes |
inhibiting |
| T18286 |
40266-40281 |
Phosphorylation |
denotes |
phosphorylation |
| T18287 |
40285-40290 |
Protein |
denotes |
c-Jun |
| T18235 |
40285-40290 |
Protein |
denotes |
c-Jun |
| T18288 |
40371-40380 |
Negative_regulation |
denotes |
reduction |
| T18289 |
40384-40388 |
Protein |
denotes |
TNFα |
| T18236 |
40384-40388 |
Protein |
denotes |
TNFα |
| T18290 |
40389-40399 |
Gene_expression |
denotes |
production |
| T18291 |
40627-40632 |
Protein |
denotes |
c-Jun |
| T18237 |
40627-40632 |
Protein |
denotes |
c-Jun |
| T18292 |
40662-40666 |
Protein |
denotes |
TNFα |
| T18238 |
40662-40666 |
Protein |
denotes |
TNFα |
| T18293 |
40667-40676 |
Gene_expression |
denotes |
synthesis |
| T18294 |
40735-40740 |
Protein |
denotes |
c-Jun |
| T18239 |
40735-40740 |
Protein |
denotes |
c-Jun |
| T18295 |
40747-40756 |
Negative_regulation |
denotes |
knockdown |
| T18296 |
40802-40817 |
Phosphorylation |
denotes |
phosphorylation |
| T18297 |
40822-40829 |
Negative_regulation |
denotes |
reduced |
| T18298 |
40872-40881 |
Regulation |
denotes |
autocrine |
| T18299 |
40882-40886 |
Protein |
denotes |
TNFα |
| T18240 |
40882-40886 |
Protein |
denotes |
TNFα |
| T18300 |
40887-40897 |
Gene_expression |
denotes |
production |
| T18301 |
40899-40908 |
Regulation |
denotes |
dependent |
| T18302 |
40912-40917 |
Protein |
denotes |
c-Jun |
| T18241 |
40912-40917 |
Protein |
denotes |
c-Jun |
| T18303 |
40951-40962 |
Positive_regulation |
denotes |
contributes |
| T18304 |
40978-40988 |
Positive_regulation |
denotes |
activation |
| T18305 |
41054-41062 |
Positive_regulation |
denotes |
increase |
| T18306 |
41087-41092 |
Protein |
denotes |
c-Jun |
| T18242 |
41087-41092 |
Protein |
denotes |
c-Jun |
| T18307 |
41140-41144 |
Protein |
denotes |
TNFα |
| T18243 |
41140-41144 |
Protein |
denotes |
TNFα |
| T18308 |
41174-41183 |
Regulation |
denotes |
dependent |
| T18309 |
41267-41272 |
Protein |
denotes |
c-Jun |
| T18244 |
41267-41272 |
Protein |
denotes |
c-Jun |
| T18310 |
41407-41422 |
Phosphorylation |
denotes |
phosphorylation |
| T18311 |
41426-41431 |
Protein |
denotes |
c-Jun |
| T18245 |
41426-41431 |
Protein |
denotes |
c-Jun |
| T20848 |
41723-41727 |
Protein |
denotes |
RIP1 |
| T20807 |
41723-41727 |
Protein |
denotes |
RIP1 |
| T20849 |
41770-41779 |
Positive_regulation |
denotes |
promoting |
| T20850 |
41792-41800 |
Positive_regulation |
denotes |
increase |
| T20851 |
41808-41823 |
Phosphorylation |
denotes |
phosphorylation |
| T20852 |
41867-41871 |
Protein |
denotes |
RIP1 |
| T20808 |
41867-41871 |
Protein |
denotes |
RIP1 |
| T20853 |
41994-41998 |
Protein |
denotes |
TNFα |
| T20809 |
41994-41998 |
Protein |
denotes |
TNFα |
| T20854 |
41999-42008 |
Gene_expression |
denotes |
synthesis |
| T20855 |
42058-42073 |
Phosphorylation |
denotes |
phosphorylation |
| T20856 |
42194-42206 |
Localization |
denotes |
localization |
| T20857 |
42269-42276 |
Protein |
denotes |
Myr-Akt |
| T20810 |
42269-42276 |
Protein |
denotes |
Myr-Akt |
| T20858 |
42323-42333 |
Gene_expression |
denotes |
expression |
| T20859 |
42337-42344 |
Protein |
denotes |
Myr-Akt |
| T20811 |
42337-42344 |
Protein |
denotes |
Myr-Akt |
| T20860 |
42431-42435 |
Protein |
denotes |
TNFα |
| T20812 |
42431-42435 |
Protein |
denotes |
TNFα |
| T20861 |
42436-42445 |
Gene_expression |
denotes |
synthesis |
| T20862 |
42457-42461 |
Protein |
denotes |
RIP1 |
| T20813 |
42457-42461 |
Protein |
denotes |
RIP1 |
| T20863 |
42488-42496 |
Positive_regulation |
denotes |
required |
| T20864 |
42508-42523 |
Phosphorylation |
denotes |
phosphorylation |
| T20865 |
42597-42612 |
Phosphorylation |
denotes |
phosphorylation |
| T20866 |
42962-42972 |
Regulation |
denotes |
regulation |
| T20867 |
43036-43040 |
Protein |
denotes |
RIP1 |
| T20814 |
43036-43040 |
Protein |
denotes |
RIP1 |
| T20868 |
43041-43050 |
Regulation |
denotes |
dependent |
| T20869 |
43051-43059 |
Positive_regulation |
denotes |
increase |
| T20870 |
43074-43089 |
Phosphorylation |
denotes |
phosphorylation |
| T20871 |
43115-43119 |
Protein |
denotes |
RIP1 |
| T20815 |
43115-43119 |
Protein |
denotes |
RIP1 |
| T20872 |
43362-43377 |
Phosphorylation |
denotes |
phosphorylation |
| T20873 |
43486-43490 |
Protein |
denotes |
RIP1 |
| T20816 |
43486-43490 |
Protein |
denotes |
RIP1 |
| T20874 |
43508-43512 |
Protein |
denotes |
PDK1 |
| T20817 |
43508-43512 |
Protein |
denotes |
PDK1 |
| T20875 |
43607-43622 |
Phosphorylation |
denotes |
phosphorylation |
| T20876 |
43645-43649 |
Protein |
denotes |
RIP1 |
| T20818 |
43645-43649 |
Protein |
denotes |
RIP1 |
| T20877 |
43762-43769 |
Protein |
denotes |
Myr-Akt |
| T20819 |
43762-43769 |
Protein |
denotes |
Myr-Akt |
| T20878 |
43864-43879 |
Phosphorylation |
denotes |
phosphorylation |
| T20879 |
44068-44083 |
Phosphorylation |
denotes |
phosphorylation |
| T20880 |
44094-44098 |
Protein |
denotes |
RIP1 |
| T20820 |
44094-44098 |
Protein |
denotes |
RIP1 |
| T20881 |
44170-44180 |
Regulation |
denotes |
regulation |
| T20882 |
44257-44261 |
Protein |
denotes |
TNFα |
| T20821 |
44257-44261 |
Protein |
denotes |
TNFα |
| T20883 |
44262-44271 |
Gene_expression |
denotes |
synthesis |
| T20884 |
44983-44987 |
Protein |
denotes |
TNFα |
| T20822 |
44983-44987 |
Protein |
denotes |
TNFα |
| T20885 |
45096-45107 |
Positive_regulation |
denotes |
contributes |
| T20886 |
45130-45134 |
Protein |
denotes |
TNFα |
| T20823 |
45130-45134 |
Protein |
denotes |
TNFα |
| T20887 |
45435-45445 |
Regulation |
denotes |
regulation |
| T20888 |
45456-45460 |
Protein |
denotes |
RIP1 |
| T20824 |
45456-45460 |
Protein |
denotes |
RIP1 |
| T20889 |
45529-45536 |
Binding |
denotes |
targets |
| T20890 |
45556-45566 |
Regulation |
denotes |
regulation |
| T20891 |
45617-45624 |
Binding |
denotes |
targets |
| T20892 |
45667-45672 |
Protein |
denotes |
FoxO1 |
| T20825 |
45667-45672 |
Protein |
denotes |
FoxO1 |
| T20893 |
45673-45674 |
Protein |
denotes |
4 |
| T20826 |
45673-45674 |
Protein |
denotes |
4 |
| T20894 |
45680-45684 |
Protein |
denotes |
MDM2 |
| T20827 |
45680-45684 |
Protein |
denotes |
MDM2 |
| T20895 |
45737-45747 |
Positive_regulation |
denotes |
activation |
| T20896 |
46185-46189 |
Protein |
denotes |
RIP1 |
| T20828 |
46185-46189 |
Protein |
denotes |
RIP1 |
| T20897 |
46456-46466 |
Positive_regulation |
denotes |
activation |
| T20898 |
46691-46698 |
Positive_regulation |
denotes |
induced |
| T20899 |
46851-46855 |
Protein |
denotes |
TNFα |
| T20829 |
46851-46855 |
Protein |
denotes |
TNFα |
| T20900 |
46968-46975 |
Positive_regulation |
denotes |
induced |
| T20901 |
46979-46983 |
Protein |
denotes |
TNFα |
| T20830 |
46979-46983 |
Protein |
denotes |
TNFα |
| T20902 |
47343-47347 |
Protein |
denotes |
RIP1 |
| T20831 |
47343-47347 |
Protein |
denotes |
RIP1 |
| T20903 |
47593-47597 |
Protein |
denotes |
FADD |
| T20832 |
47593-47597 |
Protein |
denotes |
FADD |
| T20904 |
47598-47607 |
Negative_regulation |
denotes |
deficient |
| T20905 |
47688-47696 |
Positive_regulation |
denotes |
increase |
| T20906 |
47700-47704 |
Protein |
denotes |
TNFα |
| T20833 |
47700-47704 |
Protein |
denotes |
TNFα |
| T20907 |
47705-47714 |
Gene_expression |
denotes |
synthesis |
| T20908 |
47861-47865 |
Protein |
denotes |
RIP1 |
| T20834 |
47861-47865 |
Protein |
denotes |
RIP1 |
| T20909 |
47885-47889 |
Regulation |
denotes |
role |
| T20910 |
47893-47902 |
Positive_regulation |
denotes |
mediating |
| T20911 |
47907-47917 |
Gene_expression |
denotes |
production |
| T20912 |
47921-47925 |
Protein |
denotes |
TNFα |
| T20835 |
47921-47925 |
Protein |
denotes |
TNFα |
| T20913 |
48673-48683 |
Positive_regulation |
denotes |
activation |
| T20914 |
48687-48691 |
Protein |
denotes |
TNFα |
| T20836 |
48687-48691 |
Protein |
denotes |
TNFα |
| T20915 |
48692-48701 |
Gene_expression |
denotes |
synthesis |
| T20916 |
48705-48709 |
Protein |
denotes |
RIP1 |
| T20837 |
48705-48709 |
Protein |
denotes |
RIP1 |
| T20917 |
48949-48953 |
Protein |
denotes |
RIP1 |
| T20838 |
48949-48953 |
Protein |
denotes |
RIP1 |
| T20918 |
48954-48958 |
Protein |
denotes |
RIP3 |
| T20839 |
48954-48958 |
Protein |
denotes |
RIP3 |
| T20919 |
48980-48984 |
Protein |
denotes |
FADD |
| T20840 |
48980-48984 |
Protein |
denotes |
FADD |
| T20920 |
48989-48998 |
Protein |
denotes |
caspase-8 |
| T20841 |
48989-48998 |
Protein |
denotes |
caspase-8 |
| T20921 |
49069-49073 |
Protein |
denotes |
TNFα |
| T20842 |
49069-49073 |
Protein |
denotes |
TNFα |
| T20922 |
49074-49084 |
Gene_expression |
denotes |
production |
| T20923 |
49213-49222 |
Positive_regulation |
denotes |
increased |
| T20924 |
49223-49233 |
Gene_expression |
denotes |
production |
| T20925 |
49237-49241 |
Protein |
denotes |
TNFα |
| T20843 |
49237-49241 |
Protein |
denotes |
TNFα |
| T20926 |
49582-49586 |
Protein |
denotes |
RIP1 |
| T20844 |
49582-49586 |
Protein |
denotes |
RIP1 |
| T20927 |
49591-49595 |
Protein |
denotes |
RIP3 |
| T20845 |
49591-49595 |
Protein |
denotes |
RIP3 |
| T20928 |
49642-49649 |
Positive_regulation |
denotes |
induced |
| T20929 |
49672-49676 |
Protein |
denotes |
RIP1 |
| T20846 |
49672-49676 |
Protein |
denotes |
RIP1 |
| T20930 |
49785-49789 |
Protein |
denotes |
RIP1 |
| T20847 |
49785-49789 |
Protein |
denotes |
RIP1 |
| T25124 |
50120-50129 |
Negative_regulation |
denotes |
inhibitor |
| T25125 |
50802-50806 |
Protein |
denotes |
TNFα |
| T25120 |
50802-50806 |
Protein |
denotes |
TNFα |
| T25126 |
50825-50829 |
Protein |
denotes |
bFGF |
| T25121 |
50825-50829 |
Protein |
denotes |
bFGF |
| T25127 |
50842-50845 |
Protein |
denotes |
EGF |
| T25122 |
50842-50845 |
Protein |
denotes |
EGF |
| T25128 |
50882-50887 |
Protein |
denotes |
IGF-1 |
| T25123 |
50882-50887 |
Protein |
denotes |
IGF-1 |
| T25583 |
50989-50997 |
Protein |
denotes |
Myr-Akt1 |
| T25580 |
50989-50997 |
Protein |
denotes |
Myr-Akt1 |
| T25584 |
51056-51069 |
Protein |
denotes |
Myr-Akt1-FLAG |
| T25581 |
51056-51069 |
Protein |
denotes |
Myr-Akt1-FLAG |
| T25585 |
51201-51209 |
Protein |
denotes |
Myr-Akt1 |
| T25582 |
51201-51209 |
Protein |
denotes |
Myr-Akt1 |
| T25983 |
52217-52221 |
Protein |
denotes |
TNFα |
| T25977 |
52217-52221 |
Protein |
denotes |
TNFα |
| T25984 |
52302-52305 |
Protein |
denotes |
18S |
| T25978 |
52302-52305 |
Protein |
denotes |
18S |
| T25985 |
52392-52396 |
Protein |
denotes |
TNFα |
| T25979 |
52392-52396 |
Protein |
denotes |
TNFα |
| T25986 |
52443-52447 |
Protein |
denotes |
TNFα |
| T25980 |
52443-52447 |
Protein |
denotes |
TNFα |
| T25987 |
52493-52496 |
Protein |
denotes |
18S |
| T25981 |
52493-52496 |
Protein |
denotes |
18S |
| T25988 |
52541-52544 |
Protein |
denotes |
18S |
| T25982 |
52541-52544 |
Protein |
denotes |
18S |
| T26186 |
52603-52607 |
Protein |
denotes |
FADD |
| T26185 |
52603-52607 |
Protein |
denotes |
FADD |
| T26187 |
52608-52617 |
Negative_regulation |
denotes |
deficient |
| T26713 |
54009-54013 |
Protein |
denotes |
Akt1 |
| T26706 |
54009-54013 |
Protein |
denotes |
Akt1 |
| T26714 |
54035-54039 |
Protein |
denotes |
Akt2 |
| T26707 |
54035-54039 |
Protein |
denotes |
Akt2 |
| T26715 |
54061-54065 |
Protein |
denotes |
Akt3 |
| T26708 |
54061-54065 |
Protein |
denotes |
Akt3 |
| T26716 |
54113-54117 |
Protein |
denotes |
PDK1 |
| T26709 |
54113-54117 |
Protein |
denotes |
PDK1 |
| T26717 |
54176-54181 |
Protein |
denotes |
Mapk8 |
| T26710 |
54176-54181 |
Protein |
denotes |
Mapk8 |
| T26718 |
54203-54208 |
Protein |
denotes |
Mapk9 |
| T26711 |
54203-54208 |
Protein |
denotes |
Mapk9 |
| T26719 |
54402-54406 |
Protein |
denotes |
TNFα |
| T26712 |
54402-54406 |
Protein |
denotes |
TNFα |
| T27057 |
54647-54651 |
Protein |
denotes |
TNFα |
| T27055 |
54647-54651 |
Protein |
denotes |
TNFα |
| T27058 |
54806-54810 |
Protein |
denotes |
TNFα |
| T27056 |
54806-54810 |
Protein |
denotes |
TNFα |
| T27773 |
56096-56104 |
Protein |
denotes |
Myr-Akt1 |
| T28167 |
57079-57083 |
Protein |
denotes |
TNFα |
| T28165 |
57079-57083 |
Protein |
denotes |
TNFα |
| T28168 |
57096-57100 |
Protein |
denotes |
TNFα |
| T28166 |
57096-57100 |
Protein |
denotes |
TNFα |
| T28278 |
57427-57434 |
Protein |
denotes |
Myr-Akt |
| T28277 |
57427-57434 |
Protein |
denotes |
Myr-Akt |
| R10 |
T47 |
T48 |
themeOf |
TNFα,production |
| R11 |
T48 |
T46 |
themeOf |
production,role |
| R11149 |
T16783 |
T16784 |
themeOf |
TNFα,Production |
| R11150 |
T16784 |
T16782 |
themeOf |
Production,Controls |
| R11151 |
T16786 |
T16788 |
themeOf |
Fas-associated protein with death domain,induced |
| R11152 |
T16787 |
T16786 |
equivalentTo |
FADD,Fas-associated protein with death domain |
| R11153 |
T16792 |
T16791 |
themeOf |
increase,dependent |
| R11154 |
T16793 |
T16792 |
themeOf |
phosphorylation,increase |
| R11155 |
T16794 |
T16795 |
themeOf |
TNFα,inhibited |
| R11156 |
T16796 |
T16797 |
themeOf |
RIP1,inhibitors |
| R11157 |
T16797 |
T16795 |
themeOf |
inhibitors,inhibited |
| R11158 |
T16803 |
T16804 |
themeOf |
deletion,induced |
| R11159 |
T16807 |
T16808 |
themeOf |
TNFα,mRNA production |
| R11160 |
T16808 |
T16809 |
themeOf |
mRNA production,in response to |
| R11161 |
T16810 |
T16809 |
causeOf |
TNFα,in response to |
| R11162 |
T16813 |
T16815 |
themeOf |
Akt1,phosphorylated |
| R11163 |
T16813 |
T16812 |
themeOf |
Akt1,expressing |
| R11164 |
T16814 |
T16815 |
themeOf |
Akt2,phosphorylated |
| R11165 |
T16814 |
T16812 |
themeOf |
Akt2,expressing |
| R11166 |
T16817 |
T16818 |
causeOf |
RIP1,dependent |
| R11167 |
T16819 |
T16820 |
themeOf |
TNFα,upregulation |
| R11168 |
T16820 |
T16818 |
themeOf |
upregulation,dependent |
| R11169 |
T16822 |
T16823 |
themeOf |
TNFα,synthesis |
| R11170 |
T16823 |
T16821 |
themeOf |
synthesis,autocrine |
| R12 |
T50 |
T49 |
themeOf |
RIP1,activated |
| R12106 |
T18250 |
T18249 |
themeOf |
phosphorylation,increase |
| R12107 |
T18254 |
T18253 |
themeOf |
Myr-Akt,Expression |
| R12108 |
T18256 |
T18255 |
themeOf |
Myr-Akt,expression |
| R12109 |
T18259 |
T18258 |
themeOf |
phosphorylation,required |
| R12110 |
T18267 |
T18268 |
themeOf |
TNFα,synthesis |
| R12111 |
T18268 |
T18266 |
themeOf |
synthesis,autocrine |
| R12112 |
T18271 |
T18272 |
themeOf |
TNFα,production |
| R12113 |
T18272 |
T18270 |
themeOf |
production,inhibited |
| R12114 |
T18274 |
T18273 |
themeOf |
phosphorylation,inhibited |
| R12115 |
T18278 |
T18277 |
themeOf |
phosphorylation,inhibit |
| R12116 |
T18282 |
T18281 |
themeOf |
JNK1,knockdown |
| R12117 |
T18283 |
T18281 |
themeOf |
2,knockdown |
| R12118 |
T18286 |
T18285 |
themeOf |
phosphorylation,inhibiting |
| R12119 |
T18287 |
T18286 |
themeOf |
c-Jun,phosphorylation |
| R12120 |
T18289 |
T18290 |
themeOf |
TNFα,production |
| R12121 |
T18290 |
T18288 |
themeOf |
production,reduction |
| R12122 |
T18292 |
T18293 |
themeOf |
TNFα,synthesis |
| R12123 |
T18294 |
T18295 |
themeOf |
c-Jun,knockdown |
| R12124 |
T18296 |
T18297 |
themeOf |
phosphorylation,reduced |
| R12125 |
T18298 |
T18301 |
themeOf |
autocrine,dependent |
| R12126 |
T18299 |
T18300 |
themeOf |
TNFα,production |
| R12127 |
T18300 |
T18298 |
themeOf |
production,autocrine |
| R12128 |
T18300 |
T18301 |
themeOf |
production,dependent |
| R12129 |
T18302 |
T18301 |
causeOf |
c-Jun,dependent |
| R12130 |
T18306 |
T18305 |
themeOf |
c-Jun,increase |
| R12131 |
T18307 |
T18305 |
themeOf |
TNFα,increase |
| R12132 |
T18311 |
T18310 |
themeOf |
c-Jun,phosphorylation |
| R13 |
T55 |
T54 |
themeOf |
TNFα,production |
| R13935 |
T20850 |
T20849 |
themeOf |
increase,promoting |
| R13936 |
T20851 |
T20850 |
themeOf |
phosphorylation,increase |
| R13937 |
T20853 |
T20854 |
themeOf |
TNFα,synthesis |
| R13938 |
T20859 |
T20858 |
themeOf |
Myr-Akt,expression |
| R13939 |
T20860 |
T20861 |
themeOf |
TNFα,synthesis |
| R13940 |
T20864 |
T20863 |
themeOf |
phosphorylation,required |
| R13941 |
T20867 |
T20868 |
causeOf |
RIP1,dependent |
| R13942 |
T20867 |
T20869 |
causeOf |
RIP1,increase |
| R13943 |
T20869 |
T20868 |
themeOf |
increase,dependent |
| R13944 |
T20870 |
T20869 |
themeOf |
phosphorylation,increase |
| R13945 |
T20882 |
T20883 |
themeOf |
TNFα,synthesis |
| R13946 |
T20894 |
T20891 |
themeOf |
MDM2,targets |
| R13947 |
T20901 |
T20900 |
causeOf |
TNFα,induced |
| R13948 |
T20903 |
T20904 |
themeOf |
FADD,deficient |
| R13949 |
T20906 |
T20907 |
themeOf |
TNFα,synthesis |
| R13950 |
T20907 |
T20905 |
themeOf |
synthesis,increase |
| R13951 |
T20908 |
T20909 |
causeOf |
RIP1,role |
| R13952 |
T20911 |
T20910 |
themeOf |
production,mediating |
| R13953 |
T20912 |
T20911 |
themeOf |
TNFα,production |
| R13954 |
T20914 |
T20915 |
themeOf |
TNFα,synthesis |
| R13955 |
T20915 |
T20913 |
themeOf |
synthesis,activation |
| R13956 |
T20921 |
T20922 |
themeOf |
TNFα,production |
| R13957 |
T20924 |
T20923 |
themeOf |
production,increased |
| R13958 |
T20925 |
T20924 |
themeOf |
TNFα,production |
| R14 |
T56 |
T57 |
themeOf |
TNFα,production |
| R17902 |
T26186 |
T26187 |
themeOf |
FADD,deficient |
| R1991 |
T2954 |
T2955 |
themeOf |
induction,promoted |
| R1992 |
T2956 |
T2955 |
causeOf |
bFGF,promoted |
| R20933 |
T30231 |
T30229 |
causeOf |
inhibitors,induced |
| R21208 |
T30667 |
T30666 |
themeOf |
TNFα,knockdown |
| R22002 |
T31826 |
T31827 |
themeOf |
TNFα,production |
| R22003 |
T31828 |
T31829 |
themeOf |
FADD,deficient |
| R22004 |
T31830 |
T31829 |
themeOf |
TNFα,deficient |
| R22005 |
T31835 |
T31834 |
themeOf |
TNFα,expressing |
| R22006 |
T31839 |
T31838 |
themeOf |
Akt1,expressing |
| R22007 |
T31840 |
T31838 |
themeOf |
Akt2,expressing |
| R22008 |
T31841 |
T31838 |
themeOf |
TNFα,expressing |
| R22254 |
T32296 |
T32297 |
themeOf |
TNFα,synthesis |
| R22255 |
T32298 |
T32299 |
causeOf |
Activation,leads |
| R22256 |
T32300 |
T32299 |
themeOf |
phosphorylation,leads |
| R3538 |
T5188 |
T5190 |
themeOf |
Inhibition,induced |
| R3539 |
T5188 |
T5191 |
themeOf |
Inhibition,triggered |
| R3540 |
T5193 |
T5191 |
causeOf |
IGF-1,triggered |
| R3541 |
T5202 |
T5205 |
themeOf |
knockdown,induced |
| R3542 |
T5203 |
T5202 |
themeOf |
Akt1,knockdown |
| R3543 |
T5204 |
T5202 |
themeOf |
Akt2,knockdown |
| R3544 |
T5206 |
T5205 |
causeOf |
TNFα,induced |
| R3545 |
T5208 |
T5207 |
themeOf |
Akt3,expression |
| R3546 |
T5216 |
T5215 |
themeOf |
phosphorylation,increase |
| R3547 |
T5220 |
T5219 |
themeOf |
phosphorylation,increase |
| R3548 |
T5221 |
T5220 |
themeOf |
p46,phosphorylation |
| R3549 |
T5222 |
T5220 |
themeOf |
p54,phosphorylation |
| R3550 |
T5223 |
T5220 |
themeOf |
c-Jun,phosphorylation |
| R3551 |
T5224 |
T5225 |
themeOf |
RIP1,inhibitor |
| R3552 |
T5225 |
T5227 |
causeOf |
inhibitor,increase |
| R3553 |
T5225 |
T5226 |
causeOf |
inhibitor,prevented |
| R3554 |
T5227 |
T5226 |
themeOf |
increase,prevented |
| R3555 |
T5228 |
T5229 |
themeOf |
Akt,phosphorylation |
| R3556 |
T5229 |
T5227 |
themeOf |
phosphorylation,increase |
| R3557 |
T5233 |
T5236 |
themeOf |
induced,attenuated |
| R3558 |
T5234 |
T5233 |
themeOf |
increase,induced |
| R3559 |
T5235 |
T5234 |
themeOf |
c-Jun,increase |
| R3560 |
T5235 |
T5236 |
themeOf |
c-Jun,attenuated |
| R3561 |
T5238 |
T5237 |
themeOf |
phosphorylation,alter |
| R3562 |
T5239 |
T5241 |
themeOf |
phosphorylation,dependent |
| R3563 |
T5240 |
T5239 |
themeOf |
RIP1,phosphorylation |
| R3564 |
T5242 |
T5243 |
themeOf |
phosphorylation,following |
| R3565 |
T5249 |
T5248 |
themeOf |
phosphorylation,increase |
| R3566 |
T5250 |
T5249 |
themeOf |
c-Jun,phosphorylation |
| R3567 |
T5252 |
T5253 |
causeOf |
bFGF,increase |
| R3568 |
T5254 |
T5253 |
themeOf |
phosphorylation,increase |
| R3569 |
T5258 |
T5259 |
themeOf |
c-Jun,phosphorylation |
| R3570 |
T5259 |
T5257 |
themeOf |
phosphorylation,increase |
| R3571 |
T5260 |
T5257 |
themeOf |
triggered,increase |
| R3572 |
T5261 |
T5260 |
causeOf |
bFGF,triggered |
| R3573 |
T5262 |
T5260 |
causeOf |
bFGF,triggered |
| R3574 |
T5263 |
T5264 |
causeOf |
bFGF,increase |
| R3575 |
T5268 |
T5267 |
themeOf |
phosphorylation,increase |
| R3576 |
T5270 |
T5269 |
themeOf |
phosphorylation,increase |
| R3577 |
T5271 |
T5272 |
causeOf |
RIP1,dependent |
| R3578 |
T5273 |
T5272 |
themeOf |
increase,dependent |
| R3579 |
T5274 |
T5273 |
themeOf |
phosphorylation,increase |
| R4788 |
T7388 |
T7389 |
causeOf |
TNFα,Induces |
| R4789 |
T7392 |
T7393 |
causeOf |
TNFα,induced |
| R4790 |
T7394 |
T7393 |
themeOf |
changes,induced |
| R4791 |
T7395 |
T7394 |
themeOf |
phosphorylation,changes |
| R4792 |
T7400 |
T7401 |
causeOf |
TNFα,increase |
| R4793 |
T7402 |
T7401 |
themeOf |
phosphorylation,increase |
| R4794 |
T7403 |
T7402 |
themeOf |
c-Jun,phosphorylation |
| R505 |
T853 |
T854 |
themeOf |
TNFα,production |
| R506 |
T855 |
T856 |
causeOf |
insulin,dependent |
| R507 |
T857 |
T856 |
themeOf |
activation,dependent |
| R508 |
T863 |
T865 |
causeOf |
RIP1,dependent |
| R509 |
T866 |
T865 |
themeOf |
phosphorylation,dependent |
| R510 |
T868 |
T869 |
themeOf |
TNFα,production |
| R511 |
T871 |
T872 |
themeOf |
FADD,deficient |
| R512 |
T873 |
T874 |
themeOf |
TNFα,production |
| R5255 |
T8118 |
T8117 |
themeOf |
Phosphorylation,Increase |
| R5256 |
T8121 |
T8120 |
themeOf |
phosphorylation,increase |
| R5257 |
T8129 |
T8130 |
themeOf |
bFGF,bFGF |
| R5825 |
T9007 |
T9006 |
themeOf |
phosphorylation,increase |
| R5826 |
T9009 |
T9008 |
themeOf |
phosphorylation,increase |
| R5827 |
T9010 |
T9009 |
themeOf |
double minute 2,phosphorylation |
| R5828 |
T9011 |
T9010 |
equivalentTo |
MDM2,double minute 2 |
| R5829 |
T9012 |
T9010 |
equivalentTo |
p70 ribosomal protein S6 Kinase,double minute 2 |
| R5830 |
T9013 |
T9010 |
equivalentTo |
p70S6K,double minute 2 |
| R5831 |
T9013 |
T9012 |
equivalentTo |
p70S6K,p70 ribosomal protein S6 Kinase |
| R5832 |
T9014 |
T9009 |
themeOf |
S6,phosphorylation |
| R5833 |
T9024 |
T9023 |
themeOf |
phosphorylation,increase |
| R5834 |
T9029 |
T9028 |
themeOf |
Raptor,inhibitor |
| R5835 |
T9039 |
T9040 |
themeOf |
S6,phosphorylation |
| R5836 |
T9046 |
T9045 |
themeOf |
TNFα,upregulation |
| R5837 |
T9048 |
T9047 |
themeOf |
synthesis,increased |
| R5838 |
T9049 |
T9048 |
themeOf |
TNFα,synthesis |
| R5839 |
T9051 |
T9052 |
themeOf |
TNFα,synthesis |
| R5840 |
T9052 |
T9050 |
themeOf |
synthesis,contribute |
| R5841 |
T9053 |
T9055 |
causeOf |
RIP1,increase |
| R5842 |
T9053 |
T9054 |
causeOf |
RIP1,dependent |
| R5843 |
T9055 |
T9054 |
themeOf |
increase,dependent |
| R5844 |
T9056 |
T9055 |
themeOf |
TNFα,increase |
| R5845 |
T9059 |
T9060 |
causeOf |
bFGF,triggered |
| R5846 |
T9061 |
T9063 |
themeOf |
induction,increase |
| R5847 |
T9061 |
T9060 |
themeOf |
induction,triggered |
| R5848 |
T9062 |
T9061 |
themeOf |
TNFα,induction |
| R5849 |
T9065 |
T9064 |
themeOf |
upregulation,caused |
| R5850 |
T9065 |
T9067 |
themeOf |
upregulation,increased |
| R5851 |
T9066 |
T9065 |
themeOf |
TNFα,upregulation |
| R5852 |
T9068 |
T9069 |
themeOf |
TNFα,synthesis |
| R5853 |
T9071 |
T9070 |
themeOf |
upregulation,contribute |
| R5854 |
T9072 |
T9071 |
themeOf |
TNFα,upregulation |
| R5855 |
T9073 |
T9074 |
causeOf |
knockdown,reduced |
| R5856 |
T9076 |
T9077 |
themeOf |
RIP1,inhibitors |
| R5857 |
T9077 |
T9078 |
causeOf |
inhibitors,effect |
| R5858 |
T9080 |
T9078 |
causeOf |
bFGF,effect |
| R5859 |
T9082 |
T9083 |
themeOf |
TNFα,synthesis |
| R5860 |
T9083 |
T9081 |
themeOf |
synthesis,increase |
| R6 |
T40 |
T41 |
themeOf |
TNFα,Synthesis |
| R7 |
T41 |
T39 |
themeOf |
Synthesis,Regulates |
| R7778 |
T11824 |
T11825 |
themeOf |
TNFα,synthesis |
| R7779 |
T11828 |
T11827 |
themeOf |
increase,block |
| R7780 |
T11829 |
T11828 |
themeOf |
TNFα,increase |
| R7781 |
T11831 |
T11830 |
themeOf |
Akt1,Knockdown |
| R7782 |
T11832 |
T11830 |
themeOf |
Akt2,Knockdown |
| R7783 |
T11835 |
T11836 |
themeOf |
c-Jun,phosphorylation |
| R7784 |
T11836 |
T11834 |
themeOf |
phosphorylation,increase |
| R7785 |
T11838 |
T11841 |
causeOf |
inhibition,induced |
| R7786 |
T11842 |
T11843 |
themeOf |
c-Jun,phosphorylation |
| R7787 |
T11843 |
T11841 |
themeOf |
phosphorylation,induced |
| R7788 |
T11844 |
T11846 |
causeOf |
Knockdown,attenuated |
| R7789 |
T11847 |
T11846 |
themeOf |
increase,attenuated |
| R7790 |
T11848 |
T11849 |
themeOf |
c-Jun,phosphorylation |
| R7791 |
T11849 |
T11847 |
themeOf |
phosphorylation,increase |
| R7792 |
T11849 |
T11846 |
themeOf |
phosphorylation,attenuated |
| R8 |
T44 |
T43 |
causeOf |
receptor interacting protein-1,controlled |
| R8406 |
T12724 |
T12725 |
causeOf |
PDK1,Increase |
| R8407 |
T12726 |
T12725 |
themeOf |
Phosphorylation,Increase |
| R8408 |
T12728 |
T12729 |
themeOf |
recruitment,mediated |
| R8409 |
T12731 |
T12730 |
themeOf |
pleckstrin homology,binding |
| R8410 |
T12734 |
T12733 |
causeOf |
3-phosphoinositide dependent protein kinase-1,phosphorylated |
| R8411 |
T12735 |
T12734 |
equivalentTo |
PDK1,3-phosphoinositide dependent protein kinase-1 |
| R8412 |
T12736 |
T12737 |
themeOf |
phosphorylation,increased |
| R8413 |
T12736 |
T12738 |
themeOf |
phosphorylation,dependent |
| R8414 |
T12737 |
T12738 |
themeOf |
increased,dependent |
| R8415 |
T12739 |
T12738 |
causeOf |
PDK1,dependent |
| R8416 |
T12744 |
T12743 |
themeOf |
phosphorylation,inhibited |
| R8927 |
T13598 |
T13597 |
themeOf |
Akt1,expressing |
| R8928 |
T13599 |
T13598 |
equivalentTo |
Myr-Akt,Akt1 |
| R8929 |
T13604 |
T13603 |
equivalentTo |
Myr-Akt,Akt1 |
| R8930 |
T13607 |
T13606 |
themeOf |
Myr-Akt,expressing |
| R8931 |
T13612 |
T13611 |
themeOf |
phosphorylation,increase |
| R8932 |
T13613 |
T13614 |
themeOf |
c-Jun,phosphorylation |
| R8933 |
T13616 |
T13615 |
themeOf |
TNFα,upregulation |
| R8934 |
T13621 |
T13620 |
themeOf |
activation,regulate |
| R8935 |
T13624 |
T13625 |
causeOf |
RIP1,dependent |
| R8936 |
T13626 |
T13625 |
themeOf |
phosphorylation,dependent |
| R8937 |
T13627 |
T13626 |
themeOf |
Myr-Akt,phosphorylation |
| R8938 |
T13629 |
T13628 |
themeOf |
Myr-Akt,increased |
| R8939 |
T13632 |
T13631 |
themeOf |
Myr-Akt,expression |
| R8940 |
T13633 |
T13631 |
themeOf |
K179M,expression |
| R8941 |
T13636 |
T13639 |
themeOf |
p70S6K,phosphorylated |
| R8942 |
T13637 |
T13639 |
themeOf |
S6,phosphorylated |
| R8943 |
T13638 |
T13639 |
themeOf |
FoxO4,phosphorylated |
| R8944 |
T13641 |
T13644 |
themeOf |
phosphorylation,increased |
| R8945 |
T13642 |
T13641 |
themeOf |
FoxO1,phosphorylation |
| R8946 |
T13643 |
T13641 |
themeOf |
MDM2,phosphorylation |
| R8947 |
T13646 |
T13645 |
themeOf |
Myr-Akt,phosphorylation |
| R8948 |
T13647 |
T13648 |
themeOf |
TNFα,production |
| R8949 |
T13648 |
T13649 |
themeOf |
production,dependent |
| R8950 |
T13650 |
T13649 |
themeOf |
expressed,dependent |
| R8951 |
T13651 |
T13650 |
themeOf |
Myr-Akt,expressed |
| R8952 |
T13652 |
T13653 |
themeOf |
localization,required |
| R8953 |
T13656 |
T13655 |
themeOf |
phosphorylation,increased |
| R8954 |
T13658 |
T13657 |
themeOf |
phosphorylation,role |
| R8955 |
T13662 |
T13663 |
themeOf |
S473D mutant,phosphorylated |
| R8956 |
T13663 |
T13664 |
themeOf |
phosphorylated,reduced |
| R8957 |
T13666 |
T13667 |
themeOf |
S473A,phosphorylated |
| R8958 |
T13673 |
T13672 |
themeOf |
c-Jun,phosphorylation |
| R8959 |
T13674 |
T13672 |
themeOf |
TNFα,phosphorylation |
| R8960 |
T13677 |
T13678 |
themeOf |
T308D,phosphorylated |
| R8961 |
T13679 |
T13678 |
themeOf |
Myr-Akt,phosphorylated |
| R8962 |
T13685 |
T13684 |
themeOf |
phosphorylate,allowing |
| R8963 |
T13685 |
T13686 |
causeOf |
phosphorylate,promote |
| R8964 |
T13687 |
T13688 |
themeOf |
TNFα,synthesis |
| R8965 |
T13688 |
T13686 |
themeOf |
synthesis,promote |
| R9 |
T45 |
T44 |
equivalentTo |
RIP1,receptor interacting protein-1 |
