| Id |
Subject |
Object |
Predicate |
Lexical cue |
Negation |
Speculation |
| T37 |
0-7 |
Protein |
denotes |
SHARPIN |
|
|
| T38 |
177-186 |
Negative_regulation |
denotes |
mutations |
|
|
| T39 |
194-201 |
Protein |
denotes |
Sharpin |
|
|
| T40 |
203-249 |
Protein |
denotes |
SHANK-associated RH domain-interacting protein |
|
|
| T41 |
266-272 |
Protein |
denotes |
Rbckl1 |
|
|
| T42 |
274-279 |
Protein |
denotes |
Sipl1 |
|
|
| T43 |
627-634 |
Protein |
denotes |
SHARPIN |
|
|
| T44 |
635-644 |
Negative_regulation |
denotes |
deficient |
|
|
| T45 |
749-756 |
Protein |
denotes |
SHARPIN |
|
|
| T46 |
758-768 |
Negative_regulation |
denotes |
deficiency |
|
|
| T47 |
1001-1010 |
Positive_regulation |
denotes |
increases |
|
|
| T48 |
1014-1024 |
Gene_expression |
denotes |
expression |
|
|
| T49 |
1053-1057 |
Protein |
denotes |
CD40 |
|
|
| T50 |
1059-1063 |
Protein |
denotes |
CD80 |
|
|
| T51 |
1069-1073 |
Protein |
denotes |
CD86 |
|
|
| T52 |
1095-1102 |
Protein |
denotes |
SHARPIN |
|
|
| T53 |
1103-1112 |
Negative_regulation |
denotes |
deficient |
|
|
| T54 |
1122-1129 |
Negative_regulation |
denotes |
reduced |
|
|
| T55 |
1130-1143 |
Transcription |
denotes |
transcription |
|
|
| T56 |
1188-1191 |
Protein |
denotes |
IL6 |
|
|
| T57 |
1202-1207 |
Protein |
denotes |
GMCSF |
|
|
| T58 |
1296-1301 |
Protein |
denotes |
MAPK1 |
|
|
| T59 |
1302-1303 |
Protein |
denotes |
3 |
|
|
| T60 |
1305-1309 |
Protein |
denotes |
ERK1 |
|
|
| T61 |
1310-1311 |
Protein |
denotes |
2 |
|
|
| T62 |
1317-1323 |
Protein |
denotes |
MAPK11 |
|
|
| T63 |
1324-1326 |
Protein |
denotes |
12 |
|
|
| T64 |
1327-1329 |
Protein |
denotes |
13 |
|
|
| T65 |
1330-1332 |
Protein |
denotes |
14 |
|
|
| T66 |
1363-1367 |
Protein |
denotes |
TBK1 |
|
|
| T67 |
1592-1596 |
Negative_regulation |
denotes |
loss |
|
|
| T68 |
1600-1607 |
Protein |
denotes |
Sharpin |
|
|
| T925 |
1771-1778 |
Protein |
denotes |
SHARPIN |
|
|
| T926 |
1997-2004 |
Protein |
denotes |
Sharpin |
|
|
| T927 |
2866-2875 |
Negative_regulation |
denotes |
decreased |
|
|
| T928 |
2876-2885 |
Gene_expression |
denotes |
secretion |
|
|
| T929 |
2889-2893 |
Protein |
denotes |
IFNγ |
|
|
| T930 |
3088-3102 |
Negative_regulation |
denotes |
Neutralization |
|
|
| T931 |
3106-3109 |
Protein |
denotes |
IL5 |
|
|
| T932 |
3148-3151 |
Protein |
denotes |
IL5 |
|
|
| T933 |
3152-3161 |
Negative_regulation |
denotes |
deficient |
|
|
| T934 |
3341-3348 |
Protein |
denotes |
SHARPIN |
|
|
| T935 |
3445-3449 |
Protein |
denotes |
TNFα |
|
|
| T936 |
3493-3500 |
Protein |
denotes |
SHARPIN |
|
|
| T937 |
3501-3510 |
Negative_regulation |
denotes |
deficient |
|
|
| T938 |
3563-3567 |
Protein |
denotes |
TNFα |
|
|
| T939 |
4215-4222 |
Protein |
denotes |
SHARPIN |
|
|
| T940 |
4223-4232 |
Negative_regulation |
denotes |
deficient |
|
|
| T941 |
4276-4280 |
Negative_regulation |
denotes |
lack |
|
|
| T942 |
4284-4291 |
Protein |
denotes |
SHARPIN |
|
|
| T943 |
4569-4576 |
Protein |
denotes |
SHARPIN |
|
|
| T944 |
4668-4675 |
Protein |
denotes |
SHARPIN |
|
|
| T945 |
4676-4685 |
Negative_regulation |
denotes |
deficient |
|
|
| T2184 |
4755-4762 |
Protein |
denotes |
Sharpin |
|
|
| T2185 |
4777-4784 |
Protein |
denotes |
SHARPIN |
|
|
| T2186 |
4936-4943 |
Protein |
denotes |
SHARPIN |
|
|
| T2187 |
5150-5157 |
Protein |
denotes |
SHARPIN |
|
|
| T2188 |
5214-5221 |
Protein |
denotes |
SHARPIN |
|
|
| T2189 |
5307-5314 |
Protein |
denotes |
Sharpin |
|
|
| T2190 |
5524-5534 |
Gene_expression |
denotes |
expression |
|
|
| T2191 |
5538-5545 |
Protein |
denotes |
Sharpin |
|
|
| T2192 |
5678-5685 |
Protein |
denotes |
Sharpin |
|
|
| T2193 |
5825-5834 |
Negative_regulation |
denotes |
reduction |
|
|
| T2194 |
5838-5845 |
Protein |
denotes |
Sharpin |
|
|
| T2195 |
5924-5931 |
Protein |
denotes |
Sharpin |
|
|
| T2196 |
6005-6017 |
Localization |
denotes |
localization |
|
|
| T2197 |
6025-6032 |
Protein |
denotes |
SHARPIN |
|
|
| T12745 |
6129-6136 |
Protein |
denotes |
SHARPIN |
|
true |
| T12746 |
6355-6362 |
Protein |
denotes |
SHARPIN |
|
|
| T12747 |
6716-6726 |
Transcription |
denotes |
mRNA level |
|
|
| T12748 |
6730-6737 |
Protein |
denotes |
Sharpin |
|
|
| T12749 |
6792-6807 |
Transcription |
denotes |
mRNA expression |
|
|
| T12750 |
6982-6992 |
Gene_expression |
denotes |
expression |
|
|
| T12751 |
7007-7014 |
Protein |
denotes |
SHARPIN |
|
|
| T12752 |
7183-7190 |
Protein |
denotes |
SHARPIN |
|
|
| T12753 |
7217-7226 |
Localization |
denotes |
localized |
|
|
| T2835 |
7401-7408 |
Protein |
denotes |
Sharpin |
|
|
| T2836 |
7409-7417 |
Negative_regulation |
denotes |
mutation |
|
|
| T2837 |
7536-7541 |
Protein |
denotes |
CD11c |
|
|
| T2838 |
7542-7546 |
Protein |
denotes |
CD8α |
|
|
| T2839 |
7552-7557 |
Protein |
denotes |
CD11c |
|
|
| T2840 |
7558-7562 |
Protein |
denotes |
CD8α |
|
|
| T2841 |
7596-7601 |
Protein |
denotes |
CD11c |
|
|
| T2842 |
7602-7608 |
Protein |
denotes |
PDCA-1 |
|
|
| T2843 |
7815-7823 |
Regulation |
denotes |
affected |
|
|
| T2844 |
7827-7834 |
Protein |
denotes |
SHARPIN |
|
|
| T2845 |
7835-7845 |
Negative_regulation |
denotes |
deficiency |
|
|
| T2846 |
8162-8169 |
Protein |
denotes |
Sharpin |
|
|
| T2847 |
8170-8178 |
Negative_regulation |
denotes |
mutation |
|
|
| T13259 |
8298-8304 |
Regulation |
denotes |
Effect |
|
|
| T13260 |
8308-8315 |
Protein |
denotes |
Sharpin |
|
|
| T13261 |
8316-8324 |
Negative_regulation |
denotes |
mutation |
|
|
| T2848 |
9763-9768 |
Protein |
denotes |
CD11c |
|
|
| T2849 |
9791-9801 |
Gene_expression |
denotes |
expression |
true |
|
| T2850 |
9830-9834 |
Protein |
denotes |
CD40 |
|
|
| T2851 |
9836-9840 |
Protein |
denotes |
CD80 |
true |
|
| T2852 |
9846-9850 |
Protein |
denotes |
CD86 |
|
|
| T2853 |
9856-9860 |
Protein |
denotes |
TLR3 |
true |
|
| T2854 |
9885-9889 |
Protein |
denotes |
TLR4 |
|
|
| T2855 |
9890-9896 |
Binding |
denotes |
ligand |
|
|
| T2856 |
10056-10064 |
Positive_regulation |
denotes |
resulted |
|
|
| T2857 |
10068-10077 |
Positive_regulation |
denotes |
increased |
|
|
| T2858 |
10078-10088 |
Gene_expression |
denotes |
expression |
|
|
| T2859 |
10092-10096 |
Protein |
denotes |
CD40 |
|
|
| T2860 |
10098-10102 |
Protein |
denotes |
CD80 |
|
|
| T2861 |
10108-10112 |
Protein |
denotes |
CD86 |
|
|
| T2862 |
10239-10246 |
Protein |
denotes |
SHARPIN |
|
|
| T2863 |
10247-10257 |
Negative_regulation |
denotes |
deficiency |
|
|
| T3791 |
10385-10393 |
Negative_regulation |
denotes |
impaired |
|
|
| T3792 |
10426-10434 |
Positive_regulation |
denotes |
resulted |
|
|
| T3793 |
10438-10447 |
Gene_expression |
denotes |
secretion |
|
|
| T3794 |
10451-10454 |
Protein |
denotes |
IL6 |
|
|
| T3795 |
10469-10474 |
Protein |
denotes |
GMCSF |
|
|
| T3796 |
10815-10822 |
Protein |
denotes |
Sharpin |
|
|
| T3797 |
10823-10832 |
Negative_regulation |
denotes |
deficient |
true |
|
| T3798 |
10870-10877 |
Protein |
denotes |
Sharpin |
true |
|
| T3799 |
11083-11087 |
Regulation |
denotes |
role |
|
|
| T3800 |
11091-11098 |
Protein |
denotes |
SHARPIN |
|
|
| T3801 |
11195-11198 |
Protein |
denotes |
Il6 |
|
|
| T3802 |
11200-11207 |
Protein |
denotes |
Il12p40 |
|
|
| T3803 |
11209-11214 |
Protein |
denotes |
Gmcsf |
|
|
| T3804 |
11220-11224 |
Protein |
denotes |
Ifnb |
|
|
| T13798 |
11679-11682 |
Protein |
denotes |
IL6 |
|
|
| T13799 |
11688-11693 |
Protein |
denotes |
GMCSF |
|
|
| T13800 |
11912-11915 |
Protein |
denotes |
IL6 |
|
|
| T13801 |
11981-11988 |
Protein |
denotes |
Sharpin |
|
|
| T14242 |
12673-12680 |
Regulation |
denotes |
measure |
|
true |
| T14243 |
12685-12695 |
Gene_expression |
denotes |
expression |
|
true |
| T14244 |
12699-12706 |
Protein |
denotes |
Il12p40 |
|
true |
| T14245 |
12714-12717 |
Protein |
denotes |
Il6 |
|
true |
| T14246 |
12725-12730 |
Protein |
denotes |
Gmcsf |
|
|
| T14247 |
12742-12746 |
Protein |
denotes |
Ifnb |
|
|
| T4358 |
13365-13369 |
Protein |
denotes |
TLR4 |
|
|
| T4359 |
13394-13398 |
Protein |
denotes |
CD14 |
|
|
| T4360 |
13403-13435 |
Protein |
denotes |
myeloid differentiation factor 2 |
|
|
| T4361 |
13437-13440 |
Protein |
denotes |
MD2 |
|
true |
| T4362 |
13441-13445 |
Protein |
denotes |
LY96 |
true |
|
| T4363 |
13493-13503 |
Gene_expression |
denotes |
expression |
|
|
| T4364 |
13514-13518 |
Protein |
denotes |
CD14 |
|
|
| T4365 |
13523-13527 |
Protein |
denotes |
TLR4 |
|
|
| T4366 |
13528-13531 |
Protein |
denotes |
MD2 |
|
|
| T4367 |
13643-13647 |
Protein |
denotes |
IL10 |
true |
|
| T4368 |
13802-13806 |
Protein |
denotes |
IL10 |
|
|
| T4369 |
13858-13862 |
Protein |
denotes |
IL10 |
|
|
| T4370 |
14002-14005 |
Protein |
denotes |
A20 |
|
|
| T4371 |
14062-14072 |
Transcription |
denotes |
transcript |
|
|
| T4372 |
14082-14085 |
Protein |
denotes |
A20 |
|
|
| T4373 |
14170-14184 |
Positive_regulation |
denotes |
overexpression |
|
|
| T4374 |
14188-14191 |
Protein |
denotes |
A20 |
|
|
| T14554 |
14291-14295 |
Protein |
denotes |
TLR4 |
true |
|
| T14555 |
14300-14303 |
Protein |
denotes |
MD2 |
|
|
| T14556 |
14304-14314 |
Gene_expression |
denotes |
expression |
true |
|
| T14557 |
14319-14328 |
Negative_regulation |
denotes |
decreased |
|
|
| T14558 |
14329-14333 |
Protein |
denotes |
IL10 |
|
|
| T14559 |
14334-14343 |
Localization |
denotes |
secretion |
|
|
| T14560 |
14348-14351 |
Protein |
denotes |
A20 |
|
|
| T14561 |
14352-14362 |
Gene_expression |
denotes |
expression |
|
|
| T14562 |
14764-14768 |
Protein |
denotes |
IL10 |
|
true |
| T14563 |
14992-15002 |
Gene_expression |
denotes |
production |
|
|
| T14564 |
15006-15009 |
Protein |
denotes |
A20 |
|
|
| T4375 |
15035-15039 |
Protein |
denotes |
TLR3 |
|
|
| T4376 |
15040-15041 |
Protein |
denotes |
4 |
|
|
| T4377 |
15091-15100 |
Regulation |
denotes |
regulated |
|
|
| T4378 |
15154-15158 |
Protein |
denotes |
TBK1 |
|
|
| T4379 |
15159-15163 |
Protein |
denotes |
IRF3 |
|
|
| T4380 |
15224-15228 |
Protein |
denotes |
TBK1 |
|
|
| T4381 |
15229-15233 |
Protein |
denotes |
IRF3 |
|
|
| T4382 |
15319-15326 |
Protein |
denotes |
Sharpin |
|
|
| T4383 |
15327-15336 |
Negative_regulation |
denotes |
deficient |
|
|
| T4384 |
15395-15399 |
Protein |
denotes |
IKK1 |
|
|
| T4385 |
15400-15401 |
Protein |
denotes |
2 |
|
|
| T4386 |
15453-15468 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T4387 |
15493-15504 |
Protein_catabolism |
denotes |
degradation |
|
|
| T4388 |
15528-15532 |
Protein |
denotes |
IκBα |
|
|
| T4389 |
15536-15543 |
Localization |
denotes |
release |
|
|
| T4390 |
15608-15622 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T4391 |
15623-15627 |
Protein |
denotes |
IKK1 |
|
|
| T4392 |
15628-15629 |
Protein |
denotes |
2 |
|
|
| T4393 |
15633-15637 |
Protein |
denotes |
IKK1 |
|
|
| T4394 |
15638-15639 |
Protein |
denotes |
2 |
|
|
| T4395 |
15645-15649 |
Protein |
denotes |
IκBα |
|
|
| T4396 |
15653-15657 |
Protein |
denotes |
IκBα |
|
|
| T4397 |
15659-15668 |
Positive_regulation |
denotes |
following |
|
|
| T4398 |
15714-15723 |
Negative_regulation |
denotes |
decreased |
|
|
| T4399 |
15818-15822 |
Protein |
denotes |
TBK1 |
|
|
| T4400 |
15824-15828 |
Protein |
denotes |
ERK1 |
|
|
| T4401 |
15829-15830 |
Protein |
denotes |
2 |
|
|
| T4402 |
15840-15855 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T4403 |
15919-15926 |
Negative_regulation |
denotes |
absence |
|
|
| T4404 |
15941-15948 |
Protein |
denotes |
SHARPIN |
|
|
| T4405 |
15988-15994 |
Regulation |
denotes |
affect |
|
|
| T4406 |
15995-15999 |
Protein |
denotes |
TBK1 |
|
|
| T4407 |
16000-16004 |
Protein |
denotes |
IRF3 |
|
|
| T4408 |
16006-16010 |
Protein |
denotes |
ERK1 |
|
|
| T4409 |
16011-16012 |
Protein |
denotes |
2 |
|
|
| T14977 |
16393-16397 |
Protein |
denotes |
TBK1 |
|
|
| T14978 |
16398-16402 |
Protein |
denotes |
IRF3 |
|
|
| T14979 |
16404-16408 |
Protein |
denotes |
ERK1 |
|
|
| T14980 |
16409-16410 |
Protein |
denotes |
2 |
|
|
| T14981 |
16440-16450 |
Protein |
denotes |
Beta-actin |
|
|
| T14982 |
16505-16509 |
Protein |
denotes |
IKK1 |
|
|
| T14983 |
16510-16511 |
Protein |
denotes |
2 |
|
|
| T14984 |
16518-16522 |
Protein |
denotes |
IκBα |
|
|
| T5763 |
16851-16858 |
Negative_regulation |
denotes |
absence |
|
|
| T5764 |
16862-16869 |
Protein |
denotes |
SHARPIN |
|
|
| T5765 |
17046-17054 |
Positive_regulation |
denotes |
elicited |
|
|
| T5766 |
17062-17066 |
Protein |
denotes |
IFNγ |
|
|
| T5767 |
17067-17077 |
Gene_expression |
denotes |
production |
true |
|
| T5768 |
17091-17104 |
Gene_expression |
denotes |
concentration |
|
|
| T5769 |
17108-17112 |
Protein |
denotes |
IFNγ |
|
|
| T5770 |
17273-17277 |
Protein |
denotes |
TLR3 |
|
|
| T5771 |
17278-17279 |
Protein |
denotes |
4 |
|
|
| T5772 |
17294-17298 |
Protein |
denotes |
TLR2 |
|
|
| T5773 |
17299-17305 |
Binding |
denotes |
ligand |
|
|
| T5774 |
17306-17313 |
Protein |
denotes |
Pam3CYS |
|
|
| T5775 |
17395-17402 |
Protein |
denotes |
Pam3CYS |
|
|
| T5776 |
17419-17426 |
Positive_regulation |
denotes |
induced |
|
|
| T5777 |
17434-17438 |
Protein |
denotes |
IFNγ |
|
|
| T5778 |
17439-17449 |
Gene_expression |
denotes |
production |
|
|
| T5779 |
17550-17557 |
Protein |
denotes |
Pam3CYS |
|
|
| T5780 |
17656-17665 |
Positive_regulation |
denotes |
following |
|
|
| T5781 |
17666-17670 |
Protein |
denotes |
TLR2 |
|
|
| T5782 |
17720-17723 |
Protein |
denotes |
IL4 |
|
|
| T5783 |
17861-17871 |
Gene_expression |
denotes |
production |
|
|
| T5784 |
17898-17903 |
Protein |
denotes |
IL17A |
|
|
| T5785 |
17904-17913 |
Positive_regulation |
denotes |
following |
|
|
| T5786 |
18134-18137 |
Protein |
denotes |
IL2 |
|
|
| T5787 |
18138-18148 |
Gene_expression |
denotes |
production |
|
|
| T5788 |
18237-18240 |
Protein |
denotes |
IL2 |
|
|
| T9627 |
26835-26842 |
Protein |
denotes |
Sharpin |
|
|
| T9946 |
27233-27240 |
Protein |
denotes |
Sharpin |
|
|
| T9947 |
27433-27440 |
Protein |
denotes |
Sharpin |
|
true |
| T9948 |
27546-27553 |
Gene_expression |
denotes |
express |
|
|
| T9949 |
27566-27573 |
Protein |
denotes |
SHARPIN |
|
|
| T9950 |
27705-27712 |
Protein |
denotes |
SHARPIN |
|
|
| T9951 |
27896-27903 |
Protein |
denotes |
SHARPIN |
|
|
| T9952 |
27904-27914 |
Gene_expression |
denotes |
expression |
|
|
| T11321 |
30218-30228 |
Transcription |
denotes |
expression |
|
true |
| T11322 |
30489-30499 |
Gene_expression |
denotes |
expression |
|
true |
| T11323 |
30503-30506 |
Protein |
denotes |
Il6 |
|
true |
| T11324 |
30508-30515 |
Protein |
denotes |
Il12p40 |
|
true |
| T11325 |
30517-30522 |
Protein |
denotes |
Gmcsf |
|
|
| T11326 |
30528-30535 |
Protein |
denotes |
Sharpin |
|
|
| T11327 |
30856-30883 |
Protein |
denotes |
M-MLV Reverse Transcriptase |
|
|
| T11328 |
31218-31222 |
Protein |
denotes |
Actb |
|
|
| T11329 |
31224-31227 |
Protein |
denotes |
IL6 |
|
|
| T11330 |
31229-31236 |
Protein |
denotes |
IL12p40 |
|
|
| T11331 |
31238-31242 |
Protein |
denotes |
Ifnβ |
|
|
| T11332 |
31244-31249 |
Protein |
denotes |
Gmcsf |
|
|
| T11333 |
31255-31262 |
Protein |
denotes |
Sharpin |
|
|
| T11334 |
31370-31377 |
Protein |
denotes |
β-actin |
|
|
| T12081 |
31933-31940 |
Protein |
denotes |
SHARPIN |
|
|
| T12362 |
32776-32780 |
Protein |
denotes |
IKK1 |
|
|
| T12363 |
32781-32782 |
Protein |
denotes |
2 |
|
|
| T12364 |
32793-32797 |
Protein |
denotes |
IκBα |
|
|
| T12365 |
32807-32811 |
Protein |
denotes |
IκBα |
|
|
| T12366 |
32823-32827 |
Protein |
denotes |
TBK1 |
|
|
| T12367 |
32866-32870 |
Protein |
denotes |
ERK1 |
|
|
| T12368 |
32871-32872 |
Protein |
denotes |
2 |
|
|
| T12369 |
32886-32890 |
Protein |
denotes |
ERK1 |
|
|
| T12370 |
32891-32892 |
Protein |
denotes |
2 |
|
|
| T12371 |
32902-32912 |
Protein |
denotes |
Beta-actin |
|
|
| R10552 |
T12748 |
T12749 |
themeOf |
Sharpin,mRNA expression |
| R10553 |
T12748 |
T12747 |
themeOf |
Sharpin,mRNA level |
| R10554 |
T12752 |
T12753 |
themeOf |
SHARPIN,localized |
| R11005 |
T13260 |
T13261 |
themeOf |
Sharpin,mutation |
| R11894 |
T14243 |
T14242 |
themeOf |
expression,measure |
| R11895 |
T14244 |
T14243 |
themeOf |
Il12p40,expression |
| R11896 |
T14245 |
T14243 |
themeOf |
Il6,expression |
| R11897 |
T14246 |
T14243 |
themeOf |
Gmcsf,expression |
| R11898 |
T14247 |
T14243 |
themeOf |
Ifnb,expression |
| R12172 |
T14554 |
T14556 |
themeOf |
TLR4,expression |
| R12173 |
T14555 |
T14556 |
themeOf |
MD2,expression |
| R12174 |
T14558 |
T14559 |
themeOf |
IL10,secretion |
| R12175 |
T14559 |
T14557 |
themeOf |
secretion,decreased |
| R12176 |
T14560 |
T14561 |
themeOf |
A20,expression |
| R12177 |
T14561 |
T14557 |
themeOf |
expression,decreased |
| R12178 |
T14564 |
T14563 |
themeOf |
A20,production |
| R1796 |
T2191 |
T2190 |
themeOf |
Sharpin,expression |
| R1797 |
T2194 |
T2193 |
themeOf |
Sharpin,reduction |
| R1798 |
T2197 |
T2196 |
themeOf |
SHARPIN,localization |
| R23 |
T50 |
T48 |
themeOf |
CD80,expression |
| R2318 |
T2835 |
T2836 |
themeOf |
Sharpin,mutation |
| R2319 |
T2844 |
T2845 |
themeOf |
SHARPIN,deficiency |
| R2320 |
T2845 |
T2843 |
causeOf |
deficiency,affected |
| R2321 |
T2846 |
T2847 |
themeOf |
Sharpin,mutation |
| R2322 |
T2853 |
T2855 |
themeOf |
TLR3,ligand |
| R2323 |
T2854 |
T2855 |
themeOf |
TLR4,ligand |
| R2324 |
T2857 |
T2856 |
themeOf |
increased,resulted |
| R2325 |
T2858 |
T2857 |
themeOf |
expression,increased |
| R2326 |
T2859 |
T2858 |
themeOf |
CD40,expression |
| R2327 |
T2860 |
T2858 |
themeOf |
CD80,expression |
| R2328 |
T2861 |
T2858 |
themeOf |
CD86,expression |
| R2329 |
T2862 |
T2863 |
themeOf |
SHARPIN,deficiency |
| R24 |
T51 |
T48 |
themeOf |
CD86,expression |
| R25 |
T52 |
T53 |
themeOf |
SHARPIN,deficient |
| R26 |
T53 |
T54 |
causeOf |
deficient,reduced |
| R27 |
T55 |
T54 |
themeOf |
transcription,reduced |
| R28 |
T56 |
T55 |
themeOf |
IL6,transcription |
| R29 |
T57 |
T55 |
themeOf |
GMCSF,transcription |
| R30 |
T60 |
T58 |
equivalentTo |
ERK1,MAPK1 |
| R31 |
T60 |
T59 |
equivalentTo |
ERK1,3 |
| R3122 |
T3793 |
T3792 |
themeOf |
secretion,resulted |
| R3123 |
T3794 |
T3793 |
themeOf |
IL6,secretion |
| R3124 |
T3795 |
T3793 |
themeOf |
GMCSF,secretion |
| R3125 |
T3796 |
T3797 |
themeOf |
Sharpin,deficient |
| R32 |
T61 |
T59 |
equivalentTo |
2,3 |
| R33 |
T61 |
T58 |
equivalentTo |
2,MAPK1 |
| R34 |
T68 |
T67 |
themeOf |
Sharpin,loss |
| R3576 |
T4361 |
T4360 |
equivalentTo |
MD2,myeloid differentiation factor 2 |
| R3577 |
T4362 |
T4360 |
equivalentTo |
LY96,myeloid differentiation factor 2 |
| R3578 |
T4364 |
T4363 |
themeOf |
CD14,expression |
| R3579 |
T4365 |
T4363 |
themeOf |
TLR4,expression |
| R3580 |
T4366 |
T4363 |
themeOf |
MD2,expression |
| R3581 |
T4372 |
T4371 |
themeOf |
A20,transcript |
| R3582 |
T4374 |
T4373 |
themeOf |
A20,overexpression |
| R3583 |
T4382 |
T4383 |
themeOf |
Sharpin,deficient |
| R3584 |
T4388 |
T4386 |
themeOf |
IκBα,phosphorylation |
| R3585 |
T4388 |
T4389 |
themeOf |
IκBα,release |
| R3586 |
T4388 |
T4387 |
themeOf |
IκBα,degradation |
| R3587 |
T4391 |
T4390 |
themeOf |
IKK1,phosphorylated |
| R3588 |
T4392 |
T4390 |
themeOf |
2,phosphorylated |
| R3589 |
T4395 |
T4390 |
themeOf |
IκBα,phosphorylated |
| R3590 |
T4399 |
T4402 |
themeOf |
TBK1,phosphorylation |
| R3591 |
T4400 |
T4402 |
themeOf |
ERK1,phosphorylation |
| R3592 |
T4401 |
T4402 |
themeOf |
2,phosphorylation |
| R3593 |
T4403 |
T4405 |
causeOf |
absence,affect |
| R3594 |
T4404 |
T4403 |
themeOf |
SHARPIN,absence |
| R4621 |
T5764 |
T5763 |
themeOf |
SHARPIN,absence |
| R4622 |
T5766 |
T5767 |
themeOf |
IFNγ,production |
| R4623 |
T5767 |
T5765 |
themeOf |
production,elicited |
| R4624 |
T5769 |
T5768 |
themeOf |
IFNγ,concentration |
| R4625 |
T5772 |
T5773 |
themeOf |
TLR2,ligand |
| R4626 |
T5774 |
T5773 |
themeOf |
Pam3CYS,ligand |
| R4627 |
T5775 |
T5776 |
causeOf |
Pam3CYS,induced |
| R4628 |
T5777 |
T5778 |
themeOf |
IFNγ,production |
| R4629 |
T5778 |
T5776 |
themeOf |
production,induced |
| R4630 |
T5783 |
T5785 |
themeOf |
production,following |
| R4631 |
T5784 |
T5783 |
themeOf |
IL17A,production |
| R4632 |
T5786 |
T5787 |
themeOf |
IL2,production |
| R662 |
T39 |
T38 |
themeOf |
Sharpin,mutations |
| R663 |
T40 |
T39 |
equivalentTo |
SHANK-associated RH domain-interacting protein,Sharpin |
| R664 |
T41 |
T39 |
equivalentTo |
Rbckl1,Sharpin |
| R665 |
T42 |
T38 |
themeOf |
Sipl1,mutations |
| R666 |
T42 |
T39 |
equivalentTo |
Sipl1,Sharpin |
| R667 |
T43 |
T44 |
themeOf |
SHARPIN,deficient |
| R668 |
T45 |
T46 |
themeOf |
SHARPIN,deficiency |
| R669 |
T48 |
T47 |
themeOf |
expression,increases |
| R670 |
T49 |
T48 |
themeOf |
CD40,expression |
| R732 |
T928 |
T927 |
themeOf |
secretion,decreased |
| R733 |
T929 |
T928 |
themeOf |
IFNγ,secretion |
| R734 |
T931 |
T930 |
themeOf |
IL5,Neutralization |
| R735 |
T932 |
T933 |
themeOf |
IL5,deficient |
| R736 |
T936 |
T937 |
themeOf |
SHARPIN,deficient |
| R737 |
T939 |
T940 |
themeOf |
SHARPIN,deficient |
| R738 |
T942 |
T941 |
themeOf |
SHARPIN,lack |
| R739 |
T944 |
T945 |
themeOf |
SHARPIN,deficient |
| R8180 |
T9949 |
T9948 |
themeOf |
SHARPIN,express |
| R8181 |
T9951 |
T9952 |
themeOf |
SHARPIN,expression |
| R9388 |
T11323 |
T11322 |
themeOf |
Il6,expression |
| R9389 |
T11324 |
T11322 |
themeOf |
Il12p40,expression |
| R9390 |
T11325 |
T11322 |
themeOf |
Gmcsf,expression |
| R9391 |
T11326 |
T11322 |
themeOf |
Sharpin,expression |
