| Id |
Subject |
Object |
Predicate |
Lexical cue |
Negation |
Speculation |
| T29 |
18-28 |
Regulation |
denotes |
Regulation |
|
|
| T30 |
32-37 |
Protein |
denotes |
TNF-α |
|
|
| T31 |
38-48 |
Gene_expression |
denotes |
Production |
|
true |
| T32 |
294-321 |
Protein |
denotes |
tumor necrosis factor-alpha |
|
|
| T33 |
323-328 |
Protein |
denotes |
TNF-α |
|
|
| T34 |
330-340 |
Gene_expression |
denotes |
production |
|
|
| T35 |
423-433 |
Gene_expression |
denotes |
production |
|
|
| T36 |
437-442 |
Protein |
denotes |
TNF-α |
|
|
| T37 |
443-452 |
Positive_regulation |
denotes |
following |
|
|
| T38 |
583-589 |
Regulation |
denotes |
alters |
|
|
| T39 |
590-595 |
Protein |
denotes |
TNF-α |
|
|
| T40 |
596-606 |
Gene_expression |
denotes |
production |
|
|
| T41 |
839-853 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T42 |
866-871 |
Protein |
denotes |
I-κBα |
|
|
| T43 |
891-894 |
Protein |
denotes |
p65 |
|
|
| T44 |
1060-1065 |
Protein |
denotes |
TNF-α |
|
|
| T45 |
1280-1286 |
Negative_regulation |
denotes |
reduce |
true |
|
| T46 |
1299-1304 |
Protein |
denotes |
I-κBα |
|
|
| T47 |
1305-1320 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T48 |
1330-1333 |
Protein |
denotes |
p65 |
|
|
| T49 |
1334-1349 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T50 |
1363-1370 |
Binding |
denotes |
binding |
|
|
| T51 |
1416-1424 |
Positive_regulation |
denotes |
enhanced |
|
|
| T52 |
1524-1532 |
Gene_expression |
denotes |
secreted |
|
|
| T53 |
1551-1556 |
Protein |
denotes |
TNF-α |
|
|
| T1103 |
2558-2567 |
Regulation |
denotes |
regulator |
|
|
| T1104 |
2571-2594 |
Protein |
denotes |
tumor necrosis factor-α |
|
|
| T1105 |
2596-2601 |
Protein |
denotes |
TNF-α |
|
|
| T1106 |
2603-2613 |
Gene_expression |
denotes |
production |
|
|
| T1107 |
2616-2621 |
Protein |
denotes |
TNF-α |
|
|
| T1108 |
2724-2729 |
Protein |
denotes |
TNF-α |
|
|
| T1109 |
2730-2739 |
Gene_expression |
denotes |
synthesis |
|
|
| T1110 |
2747-2757 |
Negative_regulation |
denotes |
attenuated |
|
|
| T1111 |
2964-2978 |
Negative_regulation |
denotes |
downregulation |
|
|
| T1112 |
2982-2987 |
Protein |
denotes |
TNF-α |
|
|
| T1113 |
2988-2998 |
Gene_expression |
denotes |
production |
|
|
| T1114 |
4026-4033 |
Negative_regulation |
denotes |
inhibit |
|
|
| T1115 |
4040-4049 |
Regulation |
denotes |
dependent |
|
true |
| T1116 |
4107-4112 |
Protein |
denotes |
TNF-α |
|
|
| T1117 |
4185-4195 |
Negative_regulation |
denotes |
inhibition |
|
|
| T1118 |
4196-4210 |
Negative_regulation |
denotes |
down-regulates |
|
|
| T1119 |
4211-4216 |
Protein |
denotes |
TNF-α |
|
|
| T1120 |
4217-4227 |
Gene_expression |
denotes |
production |
|
|
| T1121 |
4875-4879 |
Regulation |
denotes |
role |
|
|
| T1122 |
4894-4901 |
Positive_regulation |
denotes |
induced |
|
|
| T1123 |
4902-4907 |
Protein |
denotes |
TNF-α |
|
|
| T1124 |
4908-4918 |
Gene_expression |
denotes |
production |
|
|
| T2427 |
5667-5681 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T2428 |
5682-5686 |
Protein |
denotes |
CREB |
|
|
| T2429 |
5688-5698 |
Entity |
denotes |
serine 133 |
|
|
| T2430 |
5701-5715 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T2431 |
5716-5721 |
Protein |
denotes |
I-κBα |
|
|
| T2432 |
5723-5733 |
Entity |
denotes |
serines 32 |
|
|
| T2433 |
5738-5740 |
Entity |
denotes |
36 |
|
|
| T2434 |
5743-5757 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T2435 |
5764-5767 |
Protein |
denotes |
p65 |
|
|
| T2436 |
5784-5787 |
Entity |
denotes |
276 |
|
|
| T2437 |
6012-6017 |
Protein |
denotes |
TNF-α |
|
|
| T3236 |
8166-8173 |
Regulation |
denotes |
effects |
|
|
| T3237 |
8217-8224 |
Positive_regulation |
denotes |
induced |
|
|
| T3238 |
8225-8230 |
Protein |
denotes |
TNF-α |
|
|
| T3239 |
8231-8241 |
Gene_expression |
denotes |
production |
|
|
| T3240 |
8394-8407 |
Positive_regulation |
denotes |
up-regulation |
|
|
| T3241 |
8412-8427 |
Negative_regulation |
denotes |
down-regulation |
|
|
| T3242 |
8431-8436 |
Protein |
denotes |
TNF-α |
|
|
| T3243 |
8437-8447 |
Gene_expression |
denotes |
production |
|
|
| T3959 |
8505-8511 |
Regulation |
denotes |
Effect |
|
|
| T3960 |
8526-8533 |
Positive_regulation |
denotes |
induced |
|
|
| T3961 |
8534-8539 |
Protein |
denotes |
TNF-α |
|
|
| T3962 |
8540-8550 |
Gene_expression |
denotes |
production |
|
|
| T3963 |
8593-8598 |
Protein |
denotes |
TNF-α |
|
|
| T4121 |
8840-8845 |
Protein |
denotes |
I-κBα |
|
|
| T4122 |
8853-8856 |
Protein |
denotes |
p65 |
|
|
| T4123 |
8862-8866 |
Protein |
denotes |
CREB |
|
|
| T4124 |
9829-9843 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T4125 |
9844-9849 |
Protein |
denotes |
I-κBα |
|
|
| T4126 |
9918-9932 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T4127 |
9939-9942 |
Protein |
denotes |
p65 |
|
|
| T5611 |
12547-12554 |
Positive_regulation |
denotes |
induced |
|
|
| T5612 |
12572-12577 |
Protein |
denotes |
TNF-α |
|
|
| T5613 |
12578-12588 |
Gene_expression |
denotes |
production |
|
|
| T5614 |
12605-12609 |
Regulation |
denotes |
role |
|
|
| T5615 |
12620-12625 |
Protein |
denotes |
TNF-α |
|
|
| T5616 |
12626-12636 |
Gene_expression |
denotes |
production |
|
|
| T5617 |
12704-12711 |
Positive_regulation |
denotes |
induced |
|
|
| T5618 |
12712-12717 |
Protein |
denotes |
TNF-α |
|
|
| T5619 |
12718-12728 |
Gene_expression |
denotes |
production |
|
|
| T5620 |
12738-12747 |
Positive_regulation |
denotes |
following |
|
|
| T5621 |
13304-13309 |
Protein |
denotes |
TNF-α |
|
|
| T6219 |
13859-13866 |
Regulation |
denotes |
effects |
|
true |
| T6220 |
13881-13888 |
Positive_regulation |
denotes |
induced |
|
|
| T6221 |
13889-13894 |
Protein |
denotes |
TNF-α |
|
|
| T6222 |
13895-13905 |
Gene_expression |
denotes |
production |
|
|
| T6223 |
13939-13949 |
Negative_regulation |
denotes |
inhibition |
|
|
| T6224 |
13953-13958 |
Protein |
denotes |
TNF-α |
|
|
| T6225 |
13959-13969 |
Gene_expression |
denotes |
production |
|
|
| T6226 |
14090-14096 |
Regulation |
denotes |
effect |
|
|
| T6227 |
14100-14105 |
Protein |
denotes |
TNF-α |
|
|
| T6228 |
14106-14116 |
Gene_expression |
denotes |
production |
|
|
| T6452 |
14232-14243 |
Protein_catabolism |
denotes |
degradation |
|
|
| T6453 |
14247-14252 |
Protein |
denotes |
I-κBα |
|
|
| T6454 |
14268-14275 |
Entity |
denotes |
nuclear |
|
true |
| T6455 |
14276-14289 |
Localization |
denotes |
translocation |
|
|
| T6456 |
14322-14329 |
Regulation |
denotes |
effects |
|
|
| T6457 |
14340-14345 |
Protein |
denotes |
I-κBα |
|
|
| T6458 |
14359-14364 |
Protein |
denotes |
I-κBα |
|
|
| T6459 |
14365-14380 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6460 |
14394-14403 |
Positive_regulation |
denotes |
increased |
|
|
| T6461 |
14404-14413 |
Positive_regulation |
denotes |
following |
|
|
| T6462 |
14522-14535 |
Negative_regulation |
denotes |
downregulated |
|
|
| T6463 |
14540-14547 |
Positive_regulation |
denotes |
induced |
|
|
| T6464 |
14548-14553 |
Protein |
denotes |
I-κBα |
|
|
| T6465 |
14554-14569 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6466 |
14627-14630 |
Protein |
denotes |
p65 |
|
|
| T6467 |
14631-14646 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6468 |
14651-14660 |
Positive_regulation |
denotes |
increased |
|
|
| T6469 |
14661-14670 |
Positive_regulation |
denotes |
following |
|
|
| T6470 |
14734-14743 |
Negative_regulation |
denotes |
decreased |
|
|
| T6471 |
14748-14755 |
Positive_regulation |
denotes |
induced |
|
|
| T6472 |
14762-14765 |
Protein |
denotes |
p65 |
|
|
| T6473 |
14766-14773 |
Entity |
denotes |
nuclear |
|
|
| T6474 |
14774-14789 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6475 |
14955-14962 |
Entity |
denotes |
nuclear |
|
|
| T7077 |
16114-16123 |
Positive_regulation |
denotes |
increased |
|
|
| T7078 |
16124-16128 |
Protein |
denotes |
CREB |
|
|
| T7079 |
16133-16140 |
Binding |
denotes |
binding |
|
|
| T7570 |
16177-16183 |
Regulation |
denotes |
Effect |
|
true |
| T7571 |
16194-16199 |
Protein |
denotes |
TNF-α |
|
|
| T7572 |
16200-16210 |
Gene_expression |
denotes |
production |
|
|
| T7573 |
16268-16275 |
Positive_regulation |
denotes |
induced |
|
|
| T7574 |
16276-16290 |
Negative_regulation |
denotes |
downregulation |
|
|
| T7575 |
16294-16299 |
Protein |
denotes |
TNF-α |
|
|
| T7576 |
16300-16310 |
Gene_expression |
denotes |
production |
|
|
| T7577 |
16489-16497 |
Positive_regulation |
denotes |
resulted |
|
|
| T7578 |
16503-16512 |
Negative_regulation |
denotes |
reduction |
|
|
| T7579 |
16516-16521 |
Protein |
denotes |
TNF-α |
true |
|
| T7580 |
16720-16730 |
Regulation |
denotes |
modulation |
|
|
| T7581 |
16734-16739 |
Protein |
denotes |
TNF-α |
|
|
| T7582 |
16740-16750 |
Gene_expression |
denotes |
production |
|
|
| T7583 |
16849-16863 |
Negative_regulation |
denotes |
downregulation |
|
|
| T7584 |
16867-16872 |
Protein |
denotes |
TNF-α |
true |
|
| T7585 |
16873-16883 |
Gene_expression |
denotes |
production |
|
|
| T8176 |
17198-17203 |
Protein |
denotes |
TNF-α |
|
|
| T8177 |
17207-17215 |
Localization |
denotes |
released |
|
|
| T8178 |
17227-17236 |
Positive_regulation |
denotes |
following |
|
|
| T8179 |
17428-17437 |
Positive_regulation |
denotes |
increased |
|
|
| T8180 |
17438-17443 |
Protein |
denotes |
TNF-α |
|
|
| T8181 |
17444-17453 |
Gene_expression |
denotes |
synthesis |
|
|
| T8182 |
17673-17683 |
Negative_regulation |
denotes |
decreasing |
|
|
| T8183 |
17684-17689 |
Protein |
denotes |
TNF-α |
|
|
| T8184 |
17716-17726 |
Gene_expression |
denotes |
production |
|
|
| T8185 |
17778-17790 |
Negative_regulation |
denotes |
downregulate |
|
|
| T8186 |
17791-17796 |
Protein |
denotes |
TNF-α |
|
|
| T8187 |
17797-17807 |
Gene_expression |
denotes |
production |
|
|
| T8188 |
17887-17892 |
Protein |
denotes |
TNF-α |
|
|
| T8189 |
18015-18023 |
Negative_regulation |
denotes |
decrease |
|
|
| T8190 |
18024-18029 |
Protein |
denotes |
TNF-α |
|
true |
| T8191 |
18093-18104 |
Negative_regulation |
denotes |
attenuation |
|
|
| T8192 |
18112-18119 |
Positive_regulation |
denotes |
induced |
|
|
| T8193 |
18120-18125 |
Protein |
denotes |
TNF-α |
|
|
| T8194 |
18126-18136 |
Gene_expression |
denotes |
expression |
|
|
| T8195 |
18301-18310 |
Negative_regulation |
denotes |
decreases |
true |
|
| T8196 |
18311-18316 |
Protein |
denotes |
TNF-α |
|
|
| T8197 |
18317-18327 |
Gene_expression |
denotes |
production |
|
|
| T8198 |
18774-18785 |
Negative_regulation |
denotes |
attenuation |
|
|
| T8199 |
18789-18794 |
Protein |
denotes |
TNF-α |
|
|
| T8200 |
18795-18805 |
Gene_expression |
denotes |
production |
|
|
| T8201 |
19305-19312 |
Regulation |
denotes |
effects |
|
|
| T8202 |
19316-19321 |
Protein |
denotes |
TNF-α |
|
|
| T8203 |
19322-19331 |
Gene_expression |
denotes |
synthesis |
|
true |
| T8204 |
19409-19423 |
Negative_regulation |
denotes |
downregulation |
|
|
| T8205 |
19427-19435 |
Protein |
denotes |
TNF-αbut |
|
|
| T8206 |
20038-20041 |
Protein |
denotes |
p50 |
|
|
| T8207 |
20042-20045 |
Protein |
denotes |
p65 |
|
|
| T8208 |
20112-20117 |
Binding |
denotes |
bound |
|
|
| T8209 |
20154-20159 |
Protein |
denotes |
I-κBα |
|
|
| T8210 |
20322-20327 |
Protein |
denotes |
IKK-1 |
|
|
| T8211 |
20332-20337 |
Protein |
denotes |
IKK-2 |
|
|
| T8212 |
20353-20367 |
Phosphorylation |
denotes |
phosphorylates |
|
|
| T8213 |
20372-20377 |
Protein |
denotes |
I-κBα |
|
|
| T8214 |
20387-20402 |
Phosphorylation |
denotes |
Phosphorylation |
|
|
| T8215 |
20435-20446 |
Protein_catabolism |
denotes |
degradation |
|
|
| T8216 |
20450-20455 |
Protein |
denotes |
I-κBα |
|
|
| T8217 |
20473-20480 |
Entity |
denotes |
nuclear |
|
|
| T8218 |
20481-20494 |
Localization |
denotes |
translocation |
true |
|
| T8219 |
20536-20540 |
Binding |
denotes |
bind |
|
|
| T8220 |
20553-20560 |
Entity |
denotes |
regions |
|
|
| T8221 |
20716-20721 |
Protein |
denotes |
TNF-α |
|
|
| T8222 |
20788-20796 |
Regulation |
denotes |
involved |
true |
|
| T8223 |
20800-20805 |
Protein |
denotes |
TNF-α |
|
|
| T8224 |
20811-20821 |
Gene_expression |
denotes |
expression |
|
|
| T8225 |
20834-20843 |
Gene_expression |
denotes |
synthesis |
|
|
| T8226 |
20903-20916 |
Negative_regulation |
denotes |
downregulates |
|
|
| T8227 |
20929-20934 |
Protein |
denotes |
I-κBα |
|
|
| T8228 |
20935-20950 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T8229 |
20966-20969 |
Protein |
denotes |
p65 |
|
|
| T8230 |
20970-20985 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T8231 |
20986-20999 |
Localization |
denotes |
translocation |
|
|
| T8232 |
21022-21029 |
Binding |
denotes |
binding |
true |
|
| T8233 |
21124-21129 |
Protein |
denotes |
I-κBα |
|
|
| T8234 |
21130-21145 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T8235 |
21223-21228 |
Protein |
denotes |
I-κBα |
|
|
| T8236 |
21341-21348 |
Regulation |
denotes |
effects |
|
|
| T8237 |
21359-21364 |
Protein |
denotes |
I-κBα |
|
|
| T8238 |
21493-21504 |
Binding |
denotes |
interaction |
|
|
| T8239 |
21513-21518 |
Protein |
denotes |
I-κBα |
|
|
| T8240 |
21609-21619 |
Regulation |
denotes |
difference |
|
|
| T8241 |
21623-21628 |
Protein |
denotes |
I-κBα |
|
|
| T8242 |
21629-21640 |
Protein_catabolism |
denotes |
degradation |
|
|
| T8243 |
21884-21891 |
Positive_regulation |
denotes |
induced |
|
|
| T8244 |
21892-21900 |
Negative_regulation |
denotes |
decrease |
|
|
| T8245 |
21904-21907 |
Protein |
denotes |
p65 |
|
|
| T8246 |
21908-21923 |
Transcription |
denotes |
transcriptional |
|
|
| T8247 |
22428-22439 |
Negative_regulation |
denotes |
attenuation |
|
|
| T8248 |
22447-22454 |
Positive_regulation |
denotes |
induced |
|
|
| T8249 |
22455-22460 |
Protein |
denotes |
TNF-α |
|
|
| T8250 |
22461-22471 |
Gene_expression |
denotes |
production |
|
|
| T8251 |
22980-22987 |
Binding |
denotes |
binding |
|
|
| T8252 |
23471-23482 |
Binding |
denotes |
recruitment |
|
|
| T8253 |
23503-23506 |
Protein |
denotes |
CBP |
|
|
| T8254 |
23525-23531 |
Protein |
denotes |
p30034 |
|
|
| T8255 |
23717-23724 |
Regulation |
denotes |
effects |
|
|
| T8256 |
23778-23783 |
Protein |
denotes |
c-fos |
|
|
| T8257 |
23789-23794 |
Protein |
denotes |
c-jun |
|
|
| T8258 |
23836-23846 |
Positive_regulation |
denotes |
Activation |
|
|
| T8259 |
23875-23880 |
Protein |
denotes |
c-fos |
|
|
| T8260 |
23885-23890 |
Protein |
denotes |
c-jun |
|
|
| T8261 |
23950-23960 |
Regulation |
denotes |
implicated |
|
|
| T8262 |
23964-23969 |
Protein |
denotes |
TNF-α |
|
|
| T8263 |
23970-23980 |
Gene_expression |
denotes |
expression |
|
|
| T8264 |
24077-24082 |
Protein |
denotes |
TNF-α |
|
|
| T8265 |
24254-24264 |
Negative_regulation |
denotes |
inhibiting |
|
|
| T8266 |
24265-24270 |
Protein |
denotes |
TNF-α |
|
|
| T8267 |
24276-24289 |
Transcription |
denotes |
transcription |
|
|
| T8268 |
24652-24665 |
Positive_regulation |
denotes |
downregulates |
|
|
| T8269 |
24666-24671 |
Protein |
denotes |
TNF-α |
|
|
| T8270 |
24672-24682 |
Gene_expression |
denotes |
production |
|
|
| T8271 |
25018-25023 |
Protein |
denotes |
TNF-α |
|
|
| T8272 |
25024-25034 |
Gene_expression |
denotes |
production |
|
|
| R18 |
T30 |
T31 |
themeOf |
TNF-α,Production |
| R1877 |
T2429 |
T2428 |
partOf |
serine 133,CREB |
| R1878 |
T2429 |
T2427 |
themeOf |
serine 133,phosphorylated |
| R1879 |
T2432 |
T2430 |
themeOf |
serines 32,phosphorylated |
| R1880 |
T2432 |
T2431 |
partOf |
serines 32,I-κBα |
| R1881 |
T2433 |
T2431 |
partOf |
36,I-κBα |
| R1882 |
T2433 |
T2430 |
themeOf |
36,phosphorylated |
| R19 |
T31 |
T29 |
themeOf |
Production,Regulation |
| R20 |
T32 |
T34 |
themeOf |
tumor necrosis factor-alpha,production |
| R21 |
T35 |
T37 |
themeOf |
production,following |
| R22 |
T36 |
T35 |
themeOf |
TNF-α,production |
| R23 |
T39 |
T40 |
themeOf |
TNF-α,production |
| R24 |
T40 |
T38 |
themeOf |
production,alters |
| R25 |
T42 |
T41 |
themeOf |
I-κBα,phosphorylated |
| R2590 |
T3238 |
T3239 |
themeOf |
TNF-α,production |
| R2591 |
T3239 |
T3237 |
themeOf |
production,induced |
| R2592 |
T3242 |
T3243 |
themeOf |
TNF-α,production |
| R2593 |
T3243 |
T3241 |
themeOf |
production,down-regulation |
| R2594 |
T3243 |
T3240 |
themeOf |
production,up-regulation |
| R26 |
T46 |
T47 |
themeOf |
I-κBα,phosphorylation |
| R27 |
T47 |
T45 |
themeOf |
phosphorylation,reduce |
| R28 |
T48 |
T49 |
themeOf |
p65,phosphorylation |
| R29 |
T48 |
T50 |
themeOf |
p65,binding |
| R30 |
T49 |
T45 |
themeOf |
phosphorylation,reduce |
| R31 |
T50 |
T45 |
themeOf |
binding,reduce |
| R32 |
T53 |
T52 |
themeOf |
TNF-α,secreted |
| R3246 |
T3961 |
T3962 |
themeOf |
TNF-α,production |
| R3247 |
T3962 |
T3960 |
themeOf |
production,induced |
| R3369 |
T4125 |
T4124 |
themeOf |
I-κBα,phosphorylated |
| R3370 |
T4127 |
T4126 |
themeOf |
p65,phosphorylated |
| R4660 |
T5612 |
T5613 |
themeOf |
TNF-α,production |
| R4661 |
T5613 |
T5611 |
themeOf |
production,induced |
| R4662 |
T5615 |
T5616 |
themeOf |
TNF-α,production |
| R4663 |
T5617 |
T5620 |
themeOf |
induced,following |
| R4664 |
T5618 |
T5619 |
themeOf |
TNF-α,production |
| R4665 |
T5619 |
T5620 |
themeOf |
production,following |
| R4666 |
T5619 |
T5617 |
themeOf |
production,induced |
| R5173 |
T6221 |
T6222 |
themeOf |
TNF-α,production |
| R5174 |
T6222 |
T6220 |
themeOf |
production,induced |
| R5175 |
T6224 |
T6225 |
themeOf |
TNF-α,production |
| R5176 |
T6225 |
T6223 |
themeOf |
production,inhibition |
| R5177 |
T6227 |
T6228 |
themeOf |
TNF-α,production |
| R5178 |
T6228 |
T6226 |
themeOf |
production,effect |
| R5349 |
T6453 |
T6452 |
themeOf |
I-κBα,degradation |
| R5350 |
T6454 |
T6455 |
locationOf |
nuclear,translocation |
| R5351 |
T6457 |
T6456 |
themeOf |
I-κBα,effects |
| R5352 |
T6458 |
T6459 |
themeOf |
I-κBα,phosphorylation |
| R5353 |
T6459 |
T6460 |
themeOf |
phosphorylation,increased |
| R5354 |
T6460 |
T6461 |
themeOf |
increased,following |
| R5355 |
T6463 |
T6462 |
themeOf |
induced,downregulated |
| R5356 |
T6464 |
T6465 |
themeOf |
I-κBα,phosphorylation |
| R5357 |
T6465 |
T6463 |
themeOf |
phosphorylation,induced |
| R5358 |
T6466 |
T6467 |
themeOf |
p65,phosphorylation |
| R5359 |
T6467 |
T6468 |
themeOf |
phosphorylation,increased |
| R5360 |
T6468 |
T6469 |
themeOf |
increased,following |
| R5361 |
T6471 |
T6470 |
themeOf |
induced,decreased |
| R5362 |
T6472 |
T6474 |
themeOf |
p65,phosphorylation |
| R5363 |
T6473 |
T6474 |
locationOf |
nuclear,phosphorylation |
| R5364 |
T6474 |
T6471 |
themeOf |
phosphorylation,induced |
| R5872 |
T7078 |
T7079 |
themeOf |
CREB,binding |
| R5873 |
T7079 |
T7077 |
themeOf |
binding,increased |
| R6247 |
T7571 |
T7572 |
themeOf |
TNF-α,production |
| R6248 |
T7572 |
T7570 |
themeOf |
production,Effect |
| R6249 |
T7574 |
T7573 |
themeOf |
downregulation,induced |
| R6250 |
T7575 |
T7576 |
themeOf |
TNF-α,production |
| R6251 |
T7576 |
T7574 |
themeOf |
production,downregulation |
| R6252 |
T7578 |
T7577 |
themeOf |
reduction,resulted |
| R6253 |
T7579 |
T7578 |
themeOf |
TNF-α,reduction |
| R6254 |
T7581 |
T7582 |
themeOf |
TNF-α,production |
| R6255 |
T7582 |
T7580 |
themeOf |
production,modulation |
| R6256 |
T7584 |
T7585 |
themeOf |
TNF-α,production |
| R6257 |
T7585 |
T7583 |
themeOf |
production,downregulation |
| R6714 |
T8176 |
T8177 |
themeOf |
TNF-α,released |
| R6715 |
T8180 |
T8181 |
themeOf |
TNF-α,synthesis |
| R6716 |
T8181 |
T8179 |
themeOf |
synthesis,increased |
| R6717 |
T8183 |
T8182 |
themeOf |
TNF-α,decreasing |
| R6718 |
T8183 |
T8184 |
themeOf |
TNF-α,production |
| R6719 |
T8186 |
T8187 |
themeOf |
TNF-α,production |
| R6720 |
T8187 |
T8185 |
themeOf |
production,downregulate |
| R6721 |
T8190 |
T8189 |
themeOf |
TNF-α,decrease |
| R6722 |
T8192 |
T8191 |
themeOf |
induced,attenuation |
| R6723 |
T8193 |
T8194 |
themeOf |
TNF-α,expression |
| R6724 |
T8194 |
T8192 |
themeOf |
expression,induced |
| R6725 |
T8196 |
T8197 |
themeOf |
TNF-α,production |
| R6726 |
T8197 |
T8195 |
themeOf |
production,decreases |
| R6727 |
T8199 |
T8200 |
themeOf |
TNF-α,production |
| R6728 |
T8200 |
T8198 |
themeOf |
production,attenuation |
| R6729 |
T8202 |
T8203 |
themeOf |
TNF-α,synthesis |
| R6730 |
T8203 |
T8201 |
themeOf |
synthesis,effects |
| R6731 |
T8205 |
T8204 |
themeOf |
TNF-αbut,downregulation |
| R6732 |
T8206 |
T8208 |
themeOf |
p50,bound |
| R6733 |
T8209 |
T8208 |
themeOf |
I-κBα,bound |
| R6734 |
T8213 |
T8212 |
themeOf |
I-κBα,phosphorylates |
| R6735 |
T8216 |
T8215 |
themeOf |
I-κBα,degradation |
| R6736 |
T8216 |
T8214 |
themeOf |
I-κBα,Phosphorylation |
| R6737 |
T8217 |
T8218 |
locationOf |
nuclear,translocation |
| R6738 |
T8223 |
T8224 |
themeOf |
TNF-α,expression |
| R6739 |
T8224 |
T8222 |
themeOf |
expression,involved |
| R6740 |
T8227 |
T8228 |
themeOf |
I-κBα,phosphorylation |
| R6741 |
T8228 |
T8226 |
themeOf |
phosphorylation,downregulates |
| R6742 |
T8229 |
T8232 |
themeOf |
p65,binding |
| R6743 |
T8229 |
T8231 |
themeOf |
p65,translocation |
| R6744 |
T8229 |
T8230 |
themeOf |
p65,phosphorylation |
| R6745 |
T8230 |
T8226 |
themeOf |
phosphorylation,downregulates |
| R6746 |
T8231 |
T8226 |
themeOf |
translocation,downregulates |
| R6747 |
T8232 |
T8226 |
themeOf |
binding,downregulates |
| R6748 |
T8233 |
T8234 |
themeOf |
I-κBα,phosphorylation |
| R6749 |
T8237 |
T8236 |
themeOf |
I-κBα,effects |
| R6750 |
T8239 |
T8238 |
themeOf |
I-κBα,interaction |
| R6751 |
T8241 |
T8242 |
themeOf |
I-κBα,degradation |
| R6752 |
T8242 |
T8240 |
themeOf |
degradation,difference |
| R6753 |
T8244 |
T8243 |
themeOf |
decrease,induced |
| R6754 |
T8245 |
T8246 |
themeOf |
p65,transcriptional |
| R6755 |
T8246 |
T8244 |
themeOf |
transcriptional,decrease |
| R6756 |
T8248 |
T8247 |
themeOf |
induced,attenuation |
| R6757 |
T8249 |
T8250 |
themeOf |
TNF-α,production |
| R6758 |
T8250 |
T8248 |
themeOf |
production,induced |
| R6759 |
T8253 |
T8252 |
themeOf |
CBP,recruitment |
| R6760 |
T8254 |
T8252 |
themeOf |
p30034,recruitment |
| R6761 |
T8256 |
T8255 |
themeOf |
c-fos,effects |
| R6762 |
T8257 |
T8255 |
themeOf |
c-jun,effects |
| R6763 |
T8258 |
T8261 |
causeOf |
Activation,implicated |
| R6764 |
T8259 |
T8258 |
themeOf |
c-fos,Activation |
| R6765 |
T8260 |
T8258 |
themeOf |
c-jun,Activation |
| R6766 |
T8262 |
T8263 |
themeOf |
TNF-α,expression |
| R6767 |
T8263 |
T8261 |
themeOf |
expression,implicated |
| R6768 |
T8266 |
T8267 |
themeOf |
TNF-α,transcription |
| R6769 |
T8267 |
T8265 |
themeOf |
transcription,inhibiting |
| R6770 |
T8269 |
T8270 |
themeOf |
TNF-α,production |
| R6771 |
T8270 |
T8268 |
themeOf |
production,downregulates |
| R6772 |
T8271 |
T8272 |
themeOf |
TNF-α,production |
| R820 |
T1104 |
T1106 |
themeOf |
tumor necrosis factor-α,production |
| R821 |
T1105 |
T1104 |
equivalentTo |
TNF-α,tumor necrosis factor-α |
| R822 |
T1106 |
T1103 |
themeOf |
production,regulator |
| R823 |
T1108 |
T1109 |
themeOf |
TNF-α,synthesis |
| R824 |
T1109 |
T1110 |
themeOf |
synthesis,attenuated |
| R825 |
T1112 |
T1113 |
themeOf |
TNF-α,production |
| R826 |
T1113 |
T1111 |
themeOf |
production,downregulation |
| R827 |
T1115 |
T1114 |
themeOf |
dependent,inhibit |
| R828 |
T1119 |
T1120 |
themeOf |
TNF-α,production |
| R829 |
T1120 |
T1118 |
themeOf |
production,down-regulates |
| R830 |
T1123 |
T1124 |
themeOf |
TNF-α,production |
| R831 |
T1124 |
T1122 |
themeOf |
production,induced |