| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T0 |
0-31 |
DISEASE |
denotes |
Hypophosphatemic osteosclerosis |
| T1 |
33-45 |
DISEASE |
denotes |
hyperostosis |
| T2 |
51-63 |
DISEASE |
denotes |
enthesopathy |
| T3 |
64-74 |
REG |
denotes |
associated |
| T4 |
75-79 |
REG |
denotes |
with |
| T5 |
97-106 |
VAR |
denotes |
mutations |
| T6 |
110-114 |
GENE |
denotes |
DMP1 |
| T7 |
115-123 |
REG |
denotes |
encoding |
| T8 |
124-147 |
GENE |
denotes |
dentin matrix protein 1 |
| T9 |
124-147 |
GENE |
denotes |
dentin matrix protein 1 |
| T10 |
152-156 |
GENE |
denotes |
SPP1 |
| T11 |
157-165 |
REG |
denotes |
encoding |
| T12 |
166-177 |
GENE |
denotes |
osteopontin |
| T13 |
166-177 |
GENE |
denotes |
osteopontin |
| T14 |
197-223 |
DISEASE |
denotes |
SIBLING protein osteopathy |
| T15 |
213-223 |
DISEASE |
denotes |
osteopathy |
| T16 |
229-237 |
DISEASE |
denotes |
SIBLINGs |
| T17 |
261-301 |
GENE |
denotes |
secreted calcium-binding phosphoproteins |
| T18 |
306-314 |
REG |
denotes |
comprise |
| T19 |
326-372 |
GENE |
denotes |
integrin-binding ligand N-linked glycoproteins |
| T20 |
374-397 |
GENE |
denotes |
dentin matrix protein-1 |
| T21 |
399-403 |
GENE |
denotes |
DMP1 |
| T22 |
406-431 |
GENE |
denotes |
secreted phosphoprotein-1 |
| T23 |
433-437 |
GENE |
denotes |
SPP1 |
| T24 |
451-462 |
GENE |
denotes |
osteopontin |
| T25 |
464-467 |
GENE |
denotes |
OPN |
| T26 |
470-499 |
GENE |
denotes |
integrin-binding sialoprotein |
| T27 |
470-499 |
GENE |
denotes |
integrin-binding sialoprotein |
| T28 |
501-505 |
GENE |
denotes |
IBSP |
| T29 |
519-536 |
GENE |
denotes |
bone sialoprotein |
| T30 |
519-536 |
GENE |
denotes |
bone sialoprotein |
| T31 |
538-541 |
GENE |
denotes |
BSP |
| T32 |
544-584 |
GENE |
denotes |
matrix extracellular phosphoglycoprotein |
| T33 |
544-584 |
GENE |
denotes |
matrix extracellular phosphoglycoprotein |
| T34 |
586-590 |
GENE |
denotes |
MEPE |
| T35 |
586-590 |
GENE |
denotes |
MEPE |
| T36 |
597-623 |
GENE |
denotes |
dentin sialophosphoprotein |
| T37 |
597-623 |
GENE |
denotes |
dentin sialophosphoprotein |
| T38 |
625-629 |
GENE |
denotes |
DSPP |
| T39 |
646-649 |
REG |
denotes |
has |
| T40 |
711-716 |
VAR |
denotes |
ASARM |
| T41 |
731-745 |
VAR |
denotes |
Ser-x-Glu/pSer |
| T42 |
766-780 |
VAR |
denotes |
phosphorylated |
| T43 |
781-788 |
POSREG |
denotes |
promote |
| T44 |
789-796 |
INTERACTION |
denotes |
binding |
| T45 |
815-829 |
GENE |
denotes |
hydroxyapatite |
| T46 |
834-844 |
REG |
denotes |
regulation |
| T47 |
848-865 |
MPA |
denotes |
biomineralization |
| T48 |
892-908 |
NEGREG |
denotes |
loss-of-function |
| T49 |
939-945 |
REG |
denotes |
encode |
| T50 |
950-958 |
DISEASE |
denotes |
SIBLINGs |
| T51 |
976-980 |
GENE |
denotes |
DSPP |
| T52 |
981-988 |
REG |
denotes |
causing |
| T54 |
997-1026 |
DISEASE |
denotes |
autosomal dominant dysplasias |
| T53 |
997-1036 |
DISEASE |
denotes |
autosomal dominant dysplasias of dentin |
| T55 |
1049-1065 |
DISEASE |
denotes |
skeletal disease |
| T56 |
1071-1075 |
GENE |
denotes |
DMP1 |
| T57 |
1076-1083 |
REG |
denotes |
causing |
| T59 |
1084-1120 |
DISEASE |
denotes |
autosomal recessive hypophosphatemic |
| T58 |
1084-1136 |
DISEASE |
denotes |
autosomal recessive hypophosphatemic rickets, type 1 |
| T60 |
1138-1143 |
DISEASE |
denotes |
ARHR1 |
| T61 |
1168-1176 |
REG |
denotes |
reported |
| T62 |
1182-1198 |
POSREG |
denotes |
gain-of-function |
| T63 |
1214-1218 |
GENE |
denotes |
DSPP |
| T64 |
1222-1226 |
GENE |
denotes |
DMP1 |
| T65 |
1235-1246 |
VAR |
denotes |
alterations |
| T66 |
1250-1254 |
GENE |
denotes |
SPP1 |
| T67 |
1256-1260 |
GENE |
denotes |
IBSP |
| T68 |
1265-1269 |
GENE |
denotes |
MEPE |
| T69 |
1298-1329 |
DISEASE |
denotes |
hypophosphatemic osteosclerosis |
| T70 |
1334-1346 |
DISEASE |
denotes |
hyperostosis |
| T71 |
1347-1357 |
REG |
denotes |
associated |
| T72 |
1363-1381 |
CPA |
denotes |
skeletal deformity |
| T73 |
1363-1381 |
DISEASE |
denotes |
skeletal deformity |
| T74 |
1383-1396 |
CPA |
denotes |
short stature |
| T75 |
1398-1410 |
DISEASE |
denotes |
enthesopathy |
| T76 |
1412-1422 |
CPA |
denotes |
tooth loss |
| T77 |
1412-1422 |
DISEASE |
denotes |
tooth loss |
| T78 |
1428-1432 |
POSREG |
denotes |
high |
| T79 |
1445-1450 |
GENE |
denotes |
FGF23 |
| T80 |
1451-1457 |
MPA |
denotes |
levels |
| T81 |
1552-1558 |
REG |
denotes |
shared |
| T82 |
1576-1585 |
VAR |
denotes |
mutations |
| T83 |
1608-1614 |
REG |
denotes |
encode |
| T84 |
1634-1643 |
VAR |
denotes |
stop-gain |
| T85 |
1646-1654 |
VAR |
denotes |
nonsense |
| T86 |
1657-1661 |
GENE |
denotes |
DMP1 |
| T87 |
1663-1671 |
VAR |
denotes |
c.556G>T |
| T88 |
1674-1683 |
VAR |
denotes |
Glu186Ter |
| T89 |
1689-1697 |
VAR |
denotes |
missense |
| T90 |
1698-1702 |
GENE |
denotes |
SPP1 |
| T91 |
1704-1710 |
VAR |
denotes |
c.769C |
| T92 |
1715-1724 |
VAR |
denotes |
Leu266Phe |
| T93 |
1746-1753 |
REG |
denotes |
carried |
| T94 |
1782-1790 |
VAR |
denotes |
variants |
| T95 |
1824-1833 |
REG |
denotes |
condition |
| T96 |
1834-1853 |
MPA |
denotes |
mineral homeostasis |
| T97 |
1866-1871 |
REG |
denotes |
basis |
| T98 |
1876-1905 |
DISEASE |
denotes |
autosomal recessive disorders |
| T99 |
1907-1914 |
GENE |
denotes |
CYP27B1 |
| T100 |
1915-1925 |
REG |
denotes |
underlying |
| T101 |
1926-1961 |
DISEASE |
denotes |
vitamin D dependent rickets, type 1 |
| T102 |
1967-1972 |
GENE |
denotes |
ABCC6 |
| T103 |
1973-1983 |
REG |
denotes |
underlying |
| T104 |
1989-2042 |
DISEASE |
denotes |
generalized arterial calcification of infancy, type 2 |
| T105 |
2010-2034 |
DISEASE |
denotes |
calcification of infancy |
| T106 |
2047-2071 |
DISEASE |
denotes |
pseudoxanthoma elasticum |
| T107 |
2073-2076 |
DISEASE |
denotes |
PXE |
| T108 |
2108-2117 |
REG |
denotes |
contained |
| T109 |
2118-2122 |
POSREG |
denotes |
high |
| T110 |
2123-2130 |
MPA |
denotes |
amounts |
| T111 |
2134-2137 |
GENE |
denotes |
OPN |
| T112 |
2134-2137 |
GENE |
denotes |
OPN |
| T113 |
2254-2280 |
DISEASE |
denotes |
SIBLING protein osteopathy |
| T114 |
2270-2280 |
DISEASE |
denotes |
osteopathy |
| R0 |
T0 |
T3 |
ThemeOf |
Hypophosphatemic osteosclerosis,associated |
| R1 |
T0 |
T4 |
ThemeOf |
Hypophosphatemic osteosclerosis,with |
| R10 |
T5 |
T3 |
CauseOf |
mutations,associated |
| R100 |
T72 |
T78 |
ThemeOf |
skeletal deformity,high |
| R101 |
T74 |
T71 |
ThemeOf |
short stature,associated |
| R102 |
T74 |
T78 |
ThemeOf |
short stature,high |
| R103 |
T75 |
T71 |
ThemeOf |
enthesopathy,associated |
| R104 |
T75 |
T78 |
ThemeOf |
enthesopathy,high |
| R105 |
T75 |
T80 |
ThemeOf |
enthesopathy,levels |
| R106 |
T76 |
T71 |
ThemeOf |
tooth loss,associated |
| R107 |
T80 |
T78 |
ThemeOf |
levels,high |
| R108 |
T80 |
T71 |
ThemeOf |
levels,associated |
| R109 |
T82 |
T81 |
CauseOf |
mutations,shared |
| R11 |
T7 |
T5 |
ThemeOf |
encoding,mutations |
| R110 |
T83 |
T81 |
ThemeOf |
encode,shared |
| R111 |
T86 |
T81 |
ThemeOf |
DMP1,shared |
| R112 |
T86 |
T82 |
ThemeOf |
DMP1,mutations |
| R113 |
T86 |
T83 |
ThemeOf |
DMP1,encode |
| R114 |
T86 |
T84 |
ThemeOf |
DMP1,stop-gain |
| R115 |
T86 |
T85 |
ThemeOf |
DMP1,nonsense |
| R116 |
T86 |
T87 |
ThemeOf |
DMP1,c.556G>T |
| R117 |
T86 |
T88 |
ThemeOf |
DMP1,Glu186Ter |
| R118 |
T86 |
T89 |
ThemeOf |
DMP1,missense |
| R119 |
T86 |
T91 |
ThemeOf |
DMP1,c.769C |
| R12 |
T6 |
T5 |
ThemeOf |
DMP1,mutations |
| R120 |
T86 |
T92 |
ThemeOf |
DMP1,Leu266Phe |
| R121 |
T87 |
T88 |
ThemeOf |
c.556G>T,Glu186Ter |
| R122 |
T87 |
T89 |
ThemeOf |
c.556G>T,missense |
| R123 |
T91 |
T89 |
ThemeOf |
c.769C,missense |
| R124 |
T90 |
T82 |
ThemeOf |
SPP1,mutations |
| R125 |
T90 |
T83 |
ThemeOf |
SPP1,encode |
| R126 |
T90 |
T84 |
ThemeOf |
SPP1,stop-gain |
| R127 |
T90 |
T85 |
ThemeOf |
SPP1,nonsense |
| R128 |
T90 |
T87 |
ThemeOf |
SPP1,c.556G>T |
| R129 |
T90 |
T88 |
ThemeOf |
SPP1,Glu186Ter |
| R13 |
T6 |
T7 |
ThemeOf |
DMP1,encoding |
| R130 |
T90 |
T89 |
ThemeOf |
SPP1,missense |
| R131 |
T90 |
T91 |
ThemeOf |
SPP1,c.769C |
| R132 |
T90 |
T92 |
ThemeOf |
SPP1,Leu266Phe |
| R133 |
T91 |
T92 |
ThemeOf |
c.769C,Leu266Phe |
| R134 |
T92 |
T89 |
ThemeOf |
Leu266Phe,missense |
| R135 |
T94 |
T95 |
CauseOf |
variants,condition |
| R136 |
T94 |
T96 |
CauseOf |
variants,mineral homeostasis |
| R137 |
T94 |
T97 |
CauseOf |
variants,basis |
| R138 |
T94 |
T100 |
CauseOf |
variants,underlying |
| R139 |
T94 |
T103 |
CauseOf |
variants,underlying |
| R14 |
T6 |
T11 |
ThemeOf |
DMP1,encoding |
| R140 |
T96 |
T93 |
ThemeOf |
mineral homeostasis,carried |
| R141 |
T96 |
T95 |
ThemeOf |
mineral homeostasis,condition |
| R142 |
T96 |
T97 |
ThemeOf |
mineral homeostasis,basis |
| R143 |
T99 |
T94 |
ThemeOf |
CYP27B1,variants |
| R144 |
T101 |
T93 |
ThemeOf |
"vitamin D dependent rickets, type 1",carried |
| R145 |
T101 |
T95 |
ThemeOf |
"vitamin D dependent rickets, type 1",condition |
| R146 |
T101 |
T97 |
ThemeOf |
"vitamin D dependent rickets, type 1",basis |
| R147 |
T101 |
T100 |
ThemeOf |
"vitamin D dependent rickets, type 1",underlying |
| R148 |
T101 |
T103 |
ThemeOf |
"vitamin D dependent rickets, type 1",underlying |
| R149 |
T104 |
T93 |
ThemeOf |
"generalized arterial calcification of infancy, type 2",carried |
| R15 |
T8 |
T5 |
ThemeOf |
dentin matrix protein 1,mutations |
| R150 |
T104 |
T97 |
ThemeOf |
"generalized arterial calcification of infancy, type 2",basis |
| R151 |
T104 |
T100 |
ThemeOf |
"generalized arterial calcification of infancy, type 2",underlying |
| R152 |
T104 |
T103 |
ThemeOf |
"generalized arterial calcification of infancy, type 2",underlying |
| R153 |
T106 |
T93 |
ThemeOf |
pseudoxanthoma elasticum,carried |
| R154 |
T106 |
T95 |
ThemeOf |
pseudoxanthoma elasticum,condition |
| R155 |
T106 |
T97 |
ThemeOf |
pseudoxanthoma elasticum,basis |
| R156 |
T106 |
T100 |
ThemeOf |
pseudoxanthoma elasticum,underlying |
| R157 |
T106 |
T103 |
ThemeOf |
pseudoxanthoma elasticum,underlying |
| R158 |
T107 |
T93 |
ThemeOf |
PXE,carried |
| R159 |
T107 |
T97 |
ThemeOf |
PXE,basis |
| R16 |
T8 |
T7 |
ThemeOf |
dentin matrix protein 1,encoding |
| R160 |
T107 |
T100 |
ThemeOf |
PXE,underlying |
| R161 |
T107 |
T103 |
ThemeOf |
PXE,underlying |
| R162 |
T109 |
T108 |
ThemeOf |
high,contained |
| R163 |
T110 |
T108 |
ThemeOf |
amounts,contained |
| R164 |
T110 |
T109 |
ThemeOf |
amounts,high |
| R165 |
T111 |
T108 |
ThemeOf |
OPN,contained |
| R166 |
T111 |
T109 |
ThemeOf |
OPN,high |
| R167 |
T111 |
T110 |
ThemeOf |
OPN,amounts |
| R17 |
T8 |
T11 |
ThemeOf |
dentin matrix protein 1,encoding |
| R18 |
T10 |
T5 |
ThemeOf |
SPP1,mutations |
| R19 |
T10 |
T7 |
ThemeOf |
SPP1,encoding |
| R2 |
T0 |
T18 |
ThemeOf |
Hypophosphatemic osteosclerosis,comprise |
| R20 |
T10 |
T11 |
ThemeOf |
SPP1,encoding |
| R21 |
T12 |
T5 |
ThemeOf |
osteopontin,mutations |
| R22 |
T12 |
T7 |
ThemeOf |
osteopontin,encoding |
| R23 |
T12 |
T11 |
ThemeOf |
osteopontin,encoding |
| R24 |
T12 |
T18 |
ThemeOf |
osteopontin,comprise |
| R25 |
T15 |
T3 |
ThemeOf |
osteopathy,associated |
| R26 |
T15 |
T4 |
ThemeOf |
osteopathy,with |
| R27 |
T15 |
T7 |
ThemeOf |
osteopathy,encoding |
| R28 |
T15 |
T11 |
ThemeOf |
osteopathy,encoding |
| R29 |
T15 |
T18 |
ThemeOf |
osteopathy,comprise |
| R3 |
T1 |
T3 |
ThemeOf |
hyperostosis,associated |
| R30 |
T17 |
T18 |
ThemeOf |
secreted calcium-binding phosphoproteins,comprise |
| R31 |
T19 |
T18 |
ThemeOf |
integrin-binding ligand N-linked glycoproteins,comprise |
| R32 |
T20 |
T5 |
ThemeOf |
dentin matrix protein-1,mutations |
| R33 |
T20 |
T18 |
ThemeOf |
dentin matrix protein-1,comprise |
| R34 |
T21 |
T5 |
ThemeOf |
DMP1,mutations |
| R35 |
T21 |
T18 |
ThemeOf |
DMP1,comprise |
| R36 |
T22 |
T5 |
ThemeOf |
secreted phosphoprotein-1,mutations |
| R37 |
T22 |
T18 |
ThemeOf |
secreted phosphoprotein-1,comprise |
| R38 |
T23 |
T5 |
ThemeOf |
SPP1,mutations |
| R39 |
T23 |
T18 |
ThemeOf |
SPP1,comprise |
| R4 |
T1 |
T4 |
ThemeOf |
hyperostosis,with |
| R40 |
T24 |
T5 |
ThemeOf |
osteopontin,mutations |
| R41 |
T24 |
T18 |
ThemeOf |
osteopontin,comprise |
| R42 |
T25 |
T5 |
ThemeOf |
OPN,mutations |
| R43 |
T25 |
T18 |
ThemeOf |
OPN,comprise |
| R44 |
T26 |
T5 |
ThemeOf |
integrin-binding sialoprotein,mutations |
| R45 |
T26 |
T18 |
ThemeOf |
integrin-binding sialoprotein,comprise |
| R46 |
T28 |
T5 |
ThemeOf |
IBSP,mutations |
| R47 |
T28 |
T18 |
ThemeOf |
IBSP,comprise |
| R48 |
T29 |
T5 |
ThemeOf |
bone sialoprotein,mutations |
| R49 |
T29 |
T18 |
ThemeOf |
bone sialoprotein,comprise |
| R5 |
T2 |
T3 |
ThemeOf |
enthesopathy,associated |
| R50 |
T31 |
T5 |
ThemeOf |
BSP,mutations |
| R51 |
T31 |
T18 |
ThemeOf |
BSP,comprise |
| R52 |
T32 |
T5 |
ThemeOf |
matrix extracellular phosphoglycoprotein,mutations |
| R53 |
T32 |
T18 |
ThemeOf |
matrix extracellular phosphoglycoprotein,comprise |
| R54 |
T34 |
T18 |
ThemeOf |
MEPE,comprise |
| R55 |
T36 |
T18 |
ThemeOf |
dentin sialophosphoprotein,comprise |
| R56 |
T38 |
T18 |
ThemeOf |
DSPP,comprise |
| R57 |
T40 |
T39 |
ThemeOf |
ASARM,has |
| R58 |
T40 |
T42 |
ThemeOf |
ASARM,phosphorylated |
| R59 |
T40 |
T43 |
CauseOf |
ASARM,promote |
| R6 |
T2 |
T4 |
ThemeOf |
enthesopathy,with |
| R60 |
T41 |
T39 |
ThemeOf |
Ser-x-Glu/pSer,has |
| R61 |
T41 |
T42 |
ThemeOf |
Ser-x-Glu/pSer,phosphorylated |
| R62 |
T41 |
T43 |
CauseOf |
Ser-x-Glu/pSer,promote |
| R63 |
T41 |
T46 |
CauseOf |
Ser-x-Glu/pSer,regulation |
| R64 |
T42 |
T43 |
CauseOf |
phosphorylated,promote |
| R65 |
T42 |
T46 |
CauseOf |
phosphorylated,regulation |
| R66 |
T44 |
T43 |
ThemeOf |
binding,promote |
| R67 |
T44 |
T46 |
ThemeOf |
binding,regulation |
| R68 |
T45 |
T44 |
ThemeOf |
hydroxyapatite,binding |
| R69 |
T47 |
T46 |
ThemeOf |
biomineralization,regulation |
| R7 |
T5 |
T2 |
CauseOf |
mutations,enthesopathy |
| R70 |
T51 |
T49 |
ThemeOf |
DSPP,encode |
| R71 |
T53 |
T49 |
ThemeOf |
autosomal dominant dysplasias of dentin,encode |
| R72 |
T53 |
T52 |
ThemeOf |
autosomal dominant dysplasias of dentin,causing |
| R73 |
T53 |
T57 |
ThemeOf |
autosomal dominant dysplasias of dentin,causing |
| R74 |
T55 |
T49 |
ThemeOf |
skeletal disease,encode |
| R75 |
T55 |
T52 |
ThemeOf |
skeletal disease,causing |
| R76 |
T55 |
T57 |
ThemeOf |
skeletal disease,causing |
| R77 |
T58 |
T49 |
ThemeOf |
"autosomal recessive hypophosphatemic rickets, type 1",encode |
| R78 |
T58 |
T52 |
ThemeOf |
"autosomal recessive hypophosphatemic rickets, type 1",causing |
| R79 |
T58 |
T57 |
ThemeOf |
"autosomal recessive hypophosphatemic rickets, type 1",causing |
| R8 |
T2 |
T18 |
ThemeOf |
enthesopathy,comprise |
| R80 |
T60 |
T49 |
ThemeOf |
ARHR1,encode |
| R81 |
T60 |
T52 |
ThemeOf |
ARHR1,causing |
| R82 |
T60 |
T57 |
ThemeOf |
ARHR1,causing |
| R83 |
T63 |
T62 |
ThemeOf |
DSPP,gain-of-function |
| R84 |
T63 |
T65 |
ThemeOf |
DSPP,alterations |
| R85 |
T64 |
T62 |
ThemeOf |
DMP1,gain-of-function |
| R86 |
T64 |
T65 |
ThemeOf |
DMP1,alterations |
| R87 |
T65 |
T61 |
CauseOf |
alterations,reported |
| R88 |
T65 |
T62 |
CauseOf |
alterations,gain-of-function |
| R89 |
T66 |
T62 |
ThemeOf |
SPP1,gain-of-function |
| R9 |
T5 |
T4 |
CauseOf |
mutations,with |
| R90 |
T66 |
T65 |
ThemeOf |
SPP1,alterations |
| R91 |
T67 |
T62 |
ThemeOf |
IBSP,gain-of-function |
| R92 |
T67 |
T65 |
ThemeOf |
IBSP,alterations |
| R93 |
T68 |
T62 |
ThemeOf |
MEPE,gain-of-function |
| R94 |
T68 |
T65 |
ThemeOf |
MEPE,alterations |
| R95 |
T69 |
T71 |
ThemeOf |
hypophosphatemic osteosclerosis,associated |
| R96 |
T69 |
T78 |
ThemeOf |
hypophosphatemic osteosclerosis,high |
| R97 |
T70 |
T71 |
ThemeOf |
hyperostosis,associated |
| R98 |
T70 |
T78 |
ThemeOf |
hyperostosis,high |
| R99 |
T72 |
T71 |
ThemeOf |
skeletal deformity,associated |