| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T0 |
25-34 |
MPA |
denotes |
signaling |
| T1 |
38-63 |
DISEASE |
denotes |
polycystic kidney disease |
| T2 |
65-109 |
DISEASE |
denotes |
Autosomal dominant polycystic kidney disease |
| T3 |
111-116 |
DISEASE |
denotes |
ADPKD |
| T4 |
123-152 |
DISEASE |
denotes |
signalopathy of renal tubular |
| T5 |
139-169 |
CPA |
denotes |
renal tubular epithelial cells |
| T6 |
170-176 |
REG |
denotes |
caused |
| T7 |
177-179 |
REG |
denotes |
by |
| T8 |
190-199 |
REG |
denotes |
occurring |
| T9 |
200-209 |
VAR |
denotes |
mutations |
| T11 |
233-258 |
DISEASE |
denotes |
polycystic kidney disease |
| T10 |
233-260 |
GENE |
denotes |
polycystic kidney disease 1 |
| T12 |
262-266 |
GENE |
denotes |
PKD1 |
| T13 |
275-279 |
GENE |
denotes |
PKD2 |
| T14 |
290-298 |
VAR |
denotes |
variants |
| T15 |
302-306 |
GENE |
denotes |
PKD1 |
| T16 |
314-321 |
MPA |
denotes |
encodes |
| T17 |
326-338 |
GENE |
denotes |
polycystin-1 |
| T18 |
326-338 |
GENE |
denotes |
polycystin-1 |
| T19 |
340-344 |
GENE |
denotes |
PC-1 |
| T20 |
340-344 |
GENE |
denotes |
PC-1 |
| T21 |
355-361 |
REG |
denotes |
remain |
| T22 |
366-377 |
REG |
denotes |
predominant |
| T23 |
385-395 |
REG |
denotes |
associated |
| T24 |
405-417 |
CPA |
denotes |
pathogenesis |
| T25 |
455-464 |
REG |
denotes |
diagnosed |
| T26 |
470-473 |
DISEASE |
denotes |
PKD |
| T27 |
470-473 |
GENE |
denotes |
PKD |
| T28 |
488-500 |
REG |
denotes |
relationship |
| T29 |
509-518 |
VAR |
denotes |
defective |
| T30 |
519-523 |
GENE |
denotes |
PC-1 |
| T31 |
519-523 |
GENE |
denotes |
PC-1 |
| T32 |
529-549 |
DISEASE |
denotes |
renal cystic disease |
| T33 |
529-560 |
DISEASE |
denotes |
renal cystic disease initiation |
| T34 |
565-576 |
CPA |
denotes |
progression |
| T35 |
655-662 |
REG |
denotes |
focused |
| T36 |
672-679 |
REG |
denotes |
control |
| T37 |
735-745 |
REG |
denotes |
regulation |
| T38 |
755-764 |
REG |
denotes |
regulator |
| T39 |
772-788 |
MPA |
denotes |
activation state |
| T40 |
822-849 |
GENE |
denotes |
G protein-coupled receptors |
| T41 |
869-876 |
REG |
denotes |
defined |
| T42 |
924-928 |
GENE |
denotes |
PC-1 |
| T43 |
924-928 |
GENE |
denotes |
PC-1 |
| T44 |
952-960 |
REG |
denotes |
function |
| T45 |
1016-1020 |
GENE |
denotes |
PC-1 |
| T46 |
1016-1020 |
GENE |
denotes |
PC-1 |
| T47 |
1021-1029 |
REG |
denotes |
controls |
| T48 |
1030-1047 |
MPA |
denotes |
signal processing |
| T49 |
1049-1058 |
MPA |
denotes |
magnitude |
| T50 |
1063-1074 |
MPA |
denotes |
trafficking |
| T51 |
1153-1187 |
MPA |
denotes |
heterotrimeric G protein signaling |
| T52 |
1191-1194 |
DISEASE |
denotes |
PKD |
| T53 |
1191-1194 |
GENE |
denotes |
PKD |
| T54 |
1206-1217 |
REG |
denotes |
complicated |
| T55 |
1225-1233 |
REG |
denotes |
presence |
| T56 |
1294-1302 |
REG |
denotes |
modulate |
| T57 |
1307-1323 |
MPA |
denotes |
functional state |
| T58 |
1380-1384 |
GENE |
denotes |
PC-1 |
| T59 |
1385-1398 |
VAR |
denotes |
abnormalities |
| T60 |
1407-1414 |
REG |
denotes |
changes |
| T61 |
1418-1434 |
MPA |
denotes |
hormonal systems |
| T62 |
1451-1459 |
INTERACTION |
denotes |
interact |
| T63 |
1474-1479 |
GENE |
denotes |
GPCRs |
| T64 |
1509-1516 |
POSREG |
denotes |
amplify |
| T65 |
1520-1530 |
NEGREG |
denotes |
antagonize |
| T66 |
1531-1547 |
MPA |
denotes |
signaling output |
| T67 |
1553-1557 |
GENE |
denotes |
PC-1 |
| T68 |
1553-1557 |
GENE |
denotes |
PC-1 |
| T69 |
1605-1636 |
PATHWAY |
denotes |
noncanonical signaling pathways |
| T70 |
1652-1661 |
REG |
denotes |
described |
| T71 |
1665-1668 |
DISEASE |
denotes |
PKD |
| T72 |
1665-1668 |
GENE |
denotes |
PKD |
| T73 |
1731-1739 |
REG |
denotes |
involved |
| T74 |
1760-1774 |
REG |
denotes |
reorganization |
| T75 |
1782-1818 |
CPA |
denotes |
tubular epithelial cell architecture |
| T76 |
1822-1832 |
POSREG |
denotes |
exacerbate |
| T77 |
1833-1858 |
PATHWAY |
denotes |
renal cystogenic pathways |
| R0 |
T1 |
T0 |
ThemeOf |
polycystic kidney disease,signaling |
| R1 |
T2 |
T5 |
ThemeOf |
Autosomal dominant polycystic kidney disease,renal tubular epithelial cells |
| R10 |
T5 |
T6 |
ThemeOf |
renal tubular epithelial cells,caused |
| R100 |
T52 |
T54 |
ThemeOf |
PKD,complicated |
| R101 |
T52 |
T55 |
ThemeOf |
PKD,presence |
| R102 |
T52 |
T56 |
ThemeOf |
PKD,modulate |
| R103 |
T55 |
T54 |
CauseOf |
presence,complicated |
| R104 |
T55 |
T56 |
CauseOf |
presence,modulate |
| R105 |
T57 |
T56 |
ThemeOf |
functional state,modulate |
| R106 |
T57 |
T55 |
ThemeOf |
functional state,presence |
| R107 |
T58 |
T59 |
ThemeOf |
PC-1,abnormalities |
| R108 |
T59 |
T60 |
CauseOf |
abnormalities,changes |
| R109 |
T59 |
T64 |
CauseOf |
abnormalities,amplify |
| R11 |
T7 |
T5 |
CauseOf |
by,renal tubular epithelial cells |
| R110 |
T59 |
T65 |
CauseOf |
abnormalities,antagonize |
| R111 |
T61 |
T60 |
ThemeOf |
hormonal systems,changes |
| R112 |
T60 |
T62 |
ThemeOf |
changes,interact |
| R113 |
T61 |
T62 |
ThemeOf |
hormonal systems,interact |
| R114 |
T63 |
T62 |
ThemeOf |
GPCRs,interact |
| R115 |
T63 |
T60 |
ThemeOf |
GPCRs,changes |
| R116 |
T63 |
T61 |
ThemeOf |
GPCRs,hormonal systems |
| R117 |
T63 |
T64 |
ThemeOf |
GPCRs,amplify |
| R118 |
T65 |
T64 |
ThemeOf |
antagonize,amplify |
| R119 |
T66 |
T65 |
ThemeOf |
signaling output,antagonize |
| R12 |
T7 |
T6 |
CauseOf |
by,caused |
| R120 |
T66 |
T62 |
ThemeOf |
signaling output,interact |
| R121 |
T66 |
T64 |
ThemeOf |
signaling output,amplify |
| R122 |
T67 |
T62 |
ThemeOf |
PC-1,interact |
| R123 |
T67 |
T65 |
ThemeOf |
PC-1,antagonize |
| R124 |
T67 |
T66 |
ThemeOf |
PC-1,signaling output |
| R125 |
T69 |
T70 |
ThemeOf |
noncanonical signaling pathways,described |
| R126 |
T71 |
T69 |
ThemeOf |
PKD,noncanonical signaling pathways |
| R127 |
T71 |
T70 |
ThemeOf |
PKD,described |
| R128 |
T71 |
T73 |
ThemeOf |
PKD,involved |
| R129 |
T74 |
T73 |
ThemeOf |
reorganization,involved |
| R13 |
T8 |
T6 |
CauseOf |
occurring,caused |
| R130 |
T75 |
T74 |
ThemeOf |
tubular epithelial cell architecture,reorganization |
| R131 |
T75 |
T73 |
ThemeOf |
tubular epithelial cell architecture,involved |
| R132 |
T77 |
T73 |
ThemeOf |
renal cystogenic pathways,involved |
| R133 |
T77 |
T76 |
ThemeOf |
renal cystogenic pathways,exacerbate |
| R14 |
T9 |
T5 |
CauseOf |
mutations,renal tubular epithelial cells |
| R15 |
T9 |
T6 |
CauseOf |
mutations,caused |
| R16 |
T9 |
T7 |
CauseOf |
mutations,by |
| R17 |
T9 |
T8 |
CauseOf |
mutations,occurring |
| R18 |
T10 |
T9 |
ThemeOf |
polycystic kidney disease 1,mutations |
| R19 |
T10 |
T7 |
ThemeOf |
polycystic kidney disease 1,by |
| R2 |
T2 |
T6 |
ThemeOf |
Autosomal dominant polycystic kidney disease,caused |
| R20 |
T10 |
T8 |
ThemeOf |
polycystic kidney disease 1,occurring |
| R21 |
T12 |
T8 |
ThemeOf |
PKD1,occurring |
| R22 |
T12 |
T9 |
ThemeOf |
PKD1,mutations |
| R23 |
T13 |
T8 |
ThemeOf |
PKD2,occurring |
| R24 |
T13 |
T9 |
ThemeOf |
PKD2,mutations |
| R25 |
T14 |
T6 |
CauseOf |
variants,caused |
| R26 |
T14 |
T16 |
CauseOf |
variants,encodes |
| R27 |
T14 |
T21 |
CauseOf |
variants,remain |
| R28 |
T14 |
T22 |
CauseOf |
variants,predominant |
| R29 |
T14 |
T23 |
CauseOf |
variants,associated |
| R3 |
T2 |
T7 |
ThemeOf |
Autosomal dominant polycystic kidney disease,by |
| R30 |
T14 |
T24 |
CauseOf |
variants,pathogenesis |
| R31 |
T14 |
T25 |
CauseOf |
variants,diagnosed |
| R32 |
T15 |
T14 |
ThemeOf |
PKD1,variants |
| R33 |
T15 |
T16 |
ThemeOf |
PKD1,encodes |
| R34 |
T15 |
T21 |
ThemeOf |
PKD1,remain |
| R35 |
T15 |
T22 |
ThemeOf |
PKD1,predominant |
| R36 |
T17 |
T16 |
ThemeOf |
polycystin-1,encodes |
| R37 |
T16 |
T21 |
ThemeOf |
encodes,remain |
| R38 |
T16 |
T22 |
ThemeOf |
encodes,predominant |
| R39 |
T17 |
T14 |
ThemeOf |
polycystin-1,variants |
| R4 |
T2 |
T8 |
ThemeOf |
Autosomal dominant polycystic kidney disease,occurring |
| R40 |
T17 |
T21 |
ThemeOf |
polycystin-1,remain |
| R41 |
T17 |
T22 |
ThemeOf |
polycystin-1,predominant |
| R42 |
T17 |
T23 |
ThemeOf |
polycystin-1,associated |
| R43 |
T19 |
T14 |
ThemeOf |
PC-1,variants |
| R44 |
T19 |
T16 |
ThemeOf |
PC-1,encodes |
| R45 |
T19 |
T21 |
ThemeOf |
PC-1,remain |
| R46 |
T19 |
T22 |
ThemeOf |
PC-1,predominant |
| R47 |
T22 |
T21 |
ThemeOf |
predominant,remain |
| R48 |
T24 |
T21 |
ThemeOf |
pathogenesis,remain |
| R49 |
T23 |
T22 |
ThemeOf |
associated,predominant |
| R5 |
T3 |
T5 |
ThemeOf |
ADPKD,renal tubular epithelial cells |
| R50 |
T24 |
T22 |
ThemeOf |
pathogenesis,predominant |
| R51 |
T24 |
T23 |
ThemeOf |
pathogenesis,associated |
| R52 |
T24 |
T25 |
ThemeOf |
pathogenesis,diagnosed |
| R53 |
T25 |
T22 |
ThemeOf |
diagnosed,predominant |
| R54 |
T25 |
T23 |
ThemeOf |
diagnosed,associated |
| R55 |
T26 |
T21 |
ThemeOf |
PKD,remain |
| R56 |
T26 |
T22 |
ThemeOf |
PKD,predominant |
| R57 |
T26 |
T23 |
ThemeOf |
PKD,associated |
| R58 |
T26 |
T24 |
ThemeOf |
PKD,pathogenesis |
| R59 |
T26 |
T25 |
ThemeOf |
PKD,diagnosed |
| R6 |
T3 |
T6 |
ThemeOf |
ADPKD,caused |
| R60 |
T26 |
T28 |
ThemeOf |
PKD,relationship |
| R61 |
T32 |
T29 |
ThemeOf |
renal cystic disease,defective |
| R62 |
T29 |
T34 |
CauseOf |
defective,progression |
| R63 |
T30 |
T28 |
ThemeOf |
PC-1,relationship |
| R64 |
T30 |
T29 |
ThemeOf |
PC-1,defective |
| R65 |
T32 |
T28 |
ThemeOf |
renal cystic disease,relationship |
| R66 |
T32 |
T34 |
ThemeOf |
renal cystic disease,progression |
| R67 |
T32 |
T35 |
ThemeOf |
renal cystic disease,focused |
| R68 |
T32 |
T36 |
ThemeOf |
renal cystic disease,control |
| R69 |
T34 |
T28 |
ThemeOf |
progression,relationship |
| R7 |
T3 |
T7 |
ThemeOf |
ADPKD,by |
| R70 |
T34 |
T35 |
ThemeOf |
progression,focused |
| R71 |
T34 |
T36 |
ThemeOf |
progression,control |
| R72 |
T36 |
T35 |
ThemeOf |
control,focused |
| R73 |
T37 |
T36 |
ThemeOf |
regulation,control |
| R74 |
T37 |
T35 |
ThemeOf |
regulation,focused |
| R75 |
T39 |
T38 |
ThemeOf |
activation state,regulator |
| R76 |
T41 |
T38 |
ThemeOf |
defined,regulator |
| R77 |
T39 |
T41 |
ThemeOf |
activation state,defined |
| R78 |
T40 |
T38 |
ThemeOf |
G protein-coupled receptors,regulator |
| R79 |
T40 |
T39 |
ThemeOf |
G protein-coupled receptors,activation state |
| R8 |
T3 |
T8 |
ThemeOf |
ADPKD,occurring |
| R80 |
T40 |
T41 |
ThemeOf |
G protein-coupled receptors,defined |
| R81 |
T42 |
T44 |
ThemeOf |
PC-1,function |
| R82 |
T42 |
T48 |
ThemeOf |
PC-1,signal processing |
| R83 |
T42 |
T50 |
ThemeOf |
PC-1,trafficking |
| R84 |
T45 |
T44 |
ThemeOf |
PC-1,function |
| R85 |
T45 |
T48 |
ThemeOf |
PC-1,signal processing |
| R86 |
T45 |
T49 |
ThemeOf |
PC-1,magnitude |
| R87 |
T45 |
T50 |
ThemeOf |
PC-1,trafficking |
| R88 |
T48 |
T47 |
ThemeOf |
signal processing,controls |
| R89 |
T49 |
T47 |
ThemeOf |
magnitude,controls |
| R9 |
T9 |
T3 |
CauseOf |
mutations,ADPKD |
| R90 |
T48 |
T44 |
ThemeOf |
signal processing,function |
| R91 |
T49 |
T48 |
ThemeOf |
magnitude,signal processing |
| R92 |
T50 |
T48 |
ThemeOf |
trafficking,signal processing |
| R93 |
T49 |
T44 |
ThemeOf |
magnitude,function |
| R94 |
T50 |
T49 |
ThemeOf |
trafficking,magnitude |
| R95 |
T50 |
T44 |
ThemeOf |
trafficking,function |
| R96 |
T50 |
T47 |
ThemeOf |
trafficking,controls |
| R97 |
T51 |
T54 |
ThemeOf |
heterotrimeric G protein signaling,complicated |
| R98 |
T51 |
T55 |
ThemeOf |
heterotrimeric G protein signaling,presence |
| R99 |
T52 |
T51 |
ThemeOf |
PKD,heterotrimeric G protein signaling |
